Year : 2021
SAR Analysis of Various Heterocyclic Compounds in Medicinal Chemistry: Recent Updates-Part-I
Cite this Research Publication : Mathew, B., SAR Analysis of Various Heterocyclic Compounds in Medicinal Chemistry: Recent Updates-Part-I, Current Topics in Medicinal Chemistry, 2021, 21(30), pp. 2694, doi: 10.2174/156802662130211210151841.
Publisher : Current Topics in Medicinal Chemistry
Year : 2021
Replacement of chalcone-ethers with chalcone-thioethers as potent and highly selective monoamine oxidase-b inhibitors and their protein-ligand interactions
Cite this Research Publication : Mathew, B., Oh, J.M., Khames, A., Mathew, G.E., Kim, H. Replacement of chalcone-ethers with chalcone-thioethers as potent and highly selective monoamine oxidase-b inhibitors and their protein-ligand interactions, Pharmaceuticals, 2021, 14(11),1148, DOI: 10.3390/ph14111148
Publisher : Pharmaceuticals
Year : 2021
Synthesis of new 1-aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone oxime ether derivatives and investigation of their cytotoxic effects
Cite this Research Publication : Alagöz, M.A., Karakurt, A., Hepokur, C, Kim, H., Mathew, B. Synthesis of new 1-aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone oxime ether derivatives and investigation of their cytotoxic effects, Processes, 2021, 9(11), 2019; https://doi.org/10.3390/pr9112019
Publisher : Processes
Year : 2021
Selected Class of Enamides Bearing Nitro Functionality as Dual-Acting with Highly Selective Monoamine Oxidase-B and BACE1 Inhibitors
Cite this Research Publication : Venkidath, A., Oh, J.M., Dev, S., (...), Kim, H., Mathew, B. Selected class of enamides bearing nitro functionality as dual-acting with highly selective monoamine oxidase-b and bace1 inhibitors, Molecules, Volume 26, Issue 19, 10.3390/molecules26196004
Publisher : Molecules
Year : 2021
An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.
Cite this Research Publication : Bijo Mathew, Harilal, S., Musa, A., Kumar, R., Parambi, D. Grace Thom, Jose, J., Uddin, M. Sahab, Shah, M. Ajmal, Behl, T., and Unnikrishnan, M. Kesavan, “An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.”, Current Drug Targets, vol. 22, no. 7, pp. 823 - 834, 2021.
Publisher : Current Drug Targets
Year : 2021
A Comprehensive Overview of Colon Cancer- A Grim Reaper of the 21st Century
Cite this Research Publication : R. Kumar, Harilal, S., Carradori, S., and Bijo Mathew, “A Comprehensive Overview of Colon Cancer- A Grim Reaper of the 21st Century”, Current Medicinal Chemistry, Volume 28, (14), pp. 2657-2696, (2021)
Publisher : Current Medicinal Chemistry
Year : 2021
Revealing the role of fluorine pharmacophore in chalcone scaffold for shifting the MAO-B selectivity: investigation of a detailed molecular dynamics and quantum chemical study.
Cite this Research Publication : F. A. Olotu, Joy, M., Abdelgawad, M. A., Narayanan, S. E., Soliman, M. E., and Bijo Mathew, “Revealing the role of fluorine pharmacophore in chalcone scaffold for shifting the MAO-B selectivity: investigation of a detailed molecular dynamics and quantum chemical study.”, Journal of Biomolecular Structure and Dynamics 2021, 39(16), pp. 6126-6139
Publisher : Journal of Biomolecular Structure and Dynamics
Year : 2021
Development of methylthiosemicarbazones as new reversible monoamine oxidase-B inhibitors for the treatment of Parkinson’s disease.
Cite this Research Publication : G. Elizabeth Mathew, Oh, J. Min, Mohan, K., Tengli, A., Bijo Mathew, and Kim, H., “Development of methylthiosemicarbazones as new reversible monoamine oxidase-B inhibitors for the treatment of Parkinson's disease.”, Journal of Biomolecular Structure and Dynamics, 2021, 39(13), pp. 4786-4794.
Publisher : Journal of Biomolecular Structure and Dynamics
Year : 2021
Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations.
Cite this Research Publication : R. Sasidharan, Eom, B. Hyun, Heo, J. Hyun, Park, J. Eun, Abdelgawad, M. A., Musa, A., Gambacorta, N., Nicolotti, O., Manju, S. Leelabaiam, Bijo Mathew, and Kim, H., “Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations.”, Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 36, no. 1, pp. 188-197, 2021.
Publisher : Journal of Enzyme Inhibition and Medicinal Chemistry
Year : 2021
An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.
Cite this Research Publication : Bijo Mathew, Harilal, S., Musa, A., Kumar, R., Parambi, D. Grace Thom, Jose, J., Uddin, M. Sahab, Shah, M. Ajmal, Behl, T., and Unnikrishnan, M. Kesavan, “An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.”, Current Drug Targets, vol. 22, no. 7, pp. 823 - 834, 2021.
Publisher : Current Drug Targets
Year : 2021
COVID-19 and domestic animals: Exploring the species barrier crossing, zoonotic and reverse zoonotic transmission of SARS-CoV-2.
Cite this Research Publication : R. Kumar, Harilal, S., Al-Sehemi, A. G., Paninipara, M., Behl, T., Mathew, G. Elizabeth, and Bijo Mathew, “COVID-19 and domestic animals: Exploring the species barrier crossing, zoonotic and reverse zoonotic transmission of SARS-CoV-2.”, Current Pharmaceutical Design, Volume 27, Issue 9, pp. 1194-1201, (2021)
Publisher : Curr Pharm Des
Year : 2021
The Chronicle of COVID-19 and Possible Strategies to Curb the Pandemic
Cite this Research Publication : R. Kumar, Harilal, S., Al-Sehemi, A. G., Mathew, G. Elizabeth, Carradori, S., and Bijo Mathew, “The Chronicle of COVID-19 and Possible Strategies to Curb the Pandemic”, Current Medicinal Chemistry, 2021, 28(15), pp. 2852-2886
Publisher : Curr Med Chem,
Year : 2021
Dysregulation of the Gut-Brain Axis, Dysbiosis and Influence of Numerous Factors on Gut Microbiota Associated Parkinson’s Disease
Cite this Research Publication : G. Kaur, Behl, T., Bungau, S., Kumar, A., Uddin, M. Sahab, Mehta, V., Zengin, G., Bijo Mathew, Shah, M. Ajmal, and Arora, S., “Dysregulation of the Gut-Brain Axis, Dysbiosis and Influence of Numerous Factors on Gut Microbiota Associated Parkinson's Disease.”, Curr Neuropharmacol, vol. 19, no. 2, pp. 233-247, 2021.
Publisher : Curr Neuropharmacol
Year : 2021
New Aspects of Monoamine Oxidase B Inhibitors: The Key Role of Halogens to Open the Golden Door.
Cite this Research Publication : Bijo Mathew, Carradori, S., Guglielmi, P., Uddin, M. Sahab, and Kim, H., “New Aspects of Monoamine Oxidase B Inhibitors: The Key Role of Halogens to Open the Golden Door.”, Current Medicinal Chemistry, 2021, 28(2), pp. 266-283
Publisher : Current Medicinal Chemistry
Year : 2021
Navigating into the chemical space of monoamine oxidase inhibitors by artificial intelligence and chemoinformatics approach
Cite this Research Publication : Kumar S, Nair AS, Bhaskar V, Sudevan TS, Vishal PK, Khames A, Abdelgawad MA, and Bijo Mathew, “Navigating into the chemical space of monoamine oxidase inhibitors by artificial intelligence and chemoinformatics approach”, ACS OMEGA [Accepted], 2021.
Publisher : ACS OMEGA
Year : 2021
Ameliorative effect of ethoxylated chalcone based MAO-B inhibitor on behavioural predictors of Haloperidol-induced Parkinsonism in mice: Evidence of its anti-oxidative role against Parkinson’s diseases
Cite this Research Publication : Maliyakkal N, Saleem U, Anwar F, Shah FA, Ahmad B, Umer F, Almoyad MAA, DGT, P., Beeran AP, Nath LR, Aleya L, and Bijo Mathew, “Ameliorative effect of ethoxylated chalcone based MAO-B inhibitor on behavioural predictors of Haloperidol-induced Parkinsonism in mice: Evidence of its anti-oxidative role against Parkinson’s diseases”, Environmental Science and Pollution Research. [Accepted], 2021.
Publisher : Environmental Science and Pollution Research
Year : 2021
Recent updates on pyrazolines derivatives as promising candidates for neuropsychiartic and neurodegenerative disorders
Cite this Research Publication : Rangarajan TM and Bijo Mathew, “Recent updates on pyrazolines derivatives as promising candidates for neuropsychiartic and neurodegenerative disorders”, Current Topics in Medicinal Chemistry, 2021;21(30):2695-2714, DOI: 10.2174/1568026621999210902123132
Publisher : Current Topics in Medicinal Chemistry
Year : 2021
Insights into an Immunotherapeutic Approach to Combat Multidrug Resistance in Hepatocellular Carcinoma
Cite this Research Publication : Devan AR, Kumar AR, Nair B, Anto NP, Muraleedharan A, Bijo Mathew, Kim H, and Nath LR, “Insights into an Immunotherapeutic Approach to Combat Multidrug Resistance in Hepatocellular Carcinoma”, Pharmaceuticals, vol. 14, no. 7, p. 656, 2021.
Publisher : Pharmaceuticals
Year : 2021
Deciphering the detailed structure – activity relationship of coumarins as Monoamine oxidase enzyme inhibitors – An updated review.
Cite this Research Publication : V. Payyalot Koyiparambath, Pr, K., RangarajanT, M., Al-Sehemi, A., Pannipara, M., Bhaskar, V., Nair, A. Sujathan, Sudevan, S. Thazhathuv, Kumar, S., and Bijo Mathew, “Deciphering the detailed structure-activity relationship of coumarins as Monoamine oxidase enzyme inhibitors-An updated review.”, Chemical Biology and Drug Design, Wiley-VCH (2021), 98(4), pp. 655-673
Publisher : Wiley-VCH
Year : 2021
Current Progress in Quinazoline Derivatives as Acetylcholinesterase and Monoamine Oxidase Inhibitors
Cite this Research Publication : N. Abdul Rehuman, Al-Sehemi, A. G., Parambi, D. Grace Thom, Rangarajan, T. M., Nicolotti, O., Kim, H., and Bijo Mathew, “Current Progress in Quinazoline Derivatives as Acetylcholinesterase and Monoamine Oxidase Inhibitors”, ChemistrySelect, vol. 6, no. 28, pp. 7162-7182, 2021. DOI: https://doi.org/10.1002/slct.202101077
Publisher : ChemistrySelect
Year : 2021
Development of 2D, 3D-QSAR and pharmacophore modeling of chalcones for the inhibition of monoamine oxidase B.
Cite this Research Publication : Bijo Mathew, Acevedo, C. H., Sc, D., Rangarajan TM, MS, K., NP, N. Punnoth Po, L, S., and MT., S., “Development of 2D, 3D-QSAR and pharmacophore modeling of chalcones for the inhibition of monoamine oxidase B. ”, Combinatorial Chemistry and High Throughput Screening. (Accepted), 2021.
Publisher : Combinatorial Chemistry and High Throughput Screening
Year : 2021
Current perspective of COVID-19 on neurology: A mechanistic insight.
Cite this Research Publication : R. Kumar, Harilal, S., Pappachan, L. K., and Bijo Mathew, “Current perspective of COVID-19 on neurology: A mechanistic insight.”, Combinatorial Chemistry and High Throughput Screening (Accepted), 2021.
Publisher : Bentham Science
Year : 2021
Synthesis of N ′-(4-/3-/2-/Non-substituted benzylidene)-4-[(4-methylphenyl)sulfonyloxy] Benzohydrazides and Evaluation of Their Inhibitory Activities against Monoamine Oxidases and β-Secretase.
Cite this Research Publication : H. Erdinç Sellitepe, Oh, J. Min, Doğan, İ. Selin, Yildirim, S., Aksel, A. Buğra, Jeong, G. Seok, Khames, A., Abdelgawad, M. A., Gambacorta, N., Nicolotti, O., Bijo Mathew, and Kim, H., “Synthesis of N ′-(4-/3-/2-/Non-substituted benzylidene)-4-[(4-methylphenyl)sulfonyloxy] Benzohydrazides and Evaluation of Their Inhibitory Activities against Monoamine Oxidases and β-Secretase.”, Applied Sciences (2076-3417) , vol. 11, no. 13, pp. 5830-5830, 2021.
Publisher : Applied Sciences
Year : 2021
Trimethoxylated Halogenated Chalcones as Dual Inhibitors of MAO-B and BACE-1 for the Treatment of Neurodegenerative Disorders.
Cite this Research Publication : P. Koyiparamb Vishal, Oh, J. Min, Khames, A., Abdelgawad, M. A., Nair, A. Sujathan, Nath, L. R., Gambacorta, N., Ciriaco, F., Nicolotti, O., Kim, H., and Bijo Mathew, “Trimethoxylated Halogenated Chalcones as Dual Inhibitors of MAO-B and BACE-1 for the Treatment of Neurodegenerative Disorders.”, Pharmaceutics, vol. 13, no. 6, 2021.
Publisher : Pharmaceutics
Year : 2021
Targeting cellular batteries for the therapy of neurological diseases
Cite this Research Publication : A. Arora, Behl, T., Sehgal, A., Singh, S., Sharma, N., Bijo Mathew, and Bungau, S., “Targeting cellular batteries for the therapy of neurological diseases”, vol. 28, no. 31, pp. 41517 - 41532, 2021.
Publisher : Springer Nature
Year : 2021
Neuroprotective Effects of Ellagic Acid in Alzheimer’s Disease: Focus on Underlying Molecular Mechanisms of Therapeutic Potential.
Cite this Research Publication : N. Javaid, Shah, M. Ajmal, Rasul, A., Chauhdary, Z., Saleem, U., Khan, H., Ahmed, N., Uddin, M. Sahab, Bijo Mathew, Behl, T., and Blundell, R., “Neuroprotective Effects of Ellagic Acid in Alzheimer's Disease: Focus on Underlying Molecular Mechanisms of Therapeutic Potential.”, Current Pharmaceutical Design, Bentham Science Publishers, 2021, 27(34), pp. 3591-3601
Publisher : Bentham Science Publishers
Year : 2021
An Update of Synthetic Approaches and Structure-Activity Relationships of Various Classes of Human MAO-B Inhibitors
Cite this Research Publication : P. Sharma, Singh, D. Manjinder, and Bijo Mathew, “An Update of Synthetic Approaches and Structure-Activity Relationships of Various Classes of Human MAO-B Inhibitors”, ChemistrySelect, vol. 6, no. 7, pp. 1404-1429, 2021.
Publisher : ChemistrySelect
Year : 2021
Trimethoxy Crown Chalcones as Multifunctional Class of Monoamine Oxidase Enzyme Inhibitors.
Cite this Research Publication : N. Maliyakkal, Baysal, I., Tengli, A., Ucar, G., Almoyad, M. Ali Abdull, Parambi, D. Grace Thom, Gambacorta, N., Nicolotti, O., Beeran, A. Appadath, and Bijo Mathew, “Trimethoxy Crown Chalcones as Multifunctional Class of Monoamine Oxidase Enzyme Inhibitors.”, Combinatorial Chemistry and High Throughput Screening, 2021.
Publisher : Bentham Science
Year : 2021
Synthesis, Cytotoxicity and Anti-Proliferative Activity Against AGS Cells of New 3(2)-Pyridazinone Derivatives Endowed with a Piperazinyl Linker.
Cite this Research Publication : M. Abdullah Alagöz, Özdemir, Z., Uysal, M., Carradori, S., Gallorini, M., Ricci, A., Zara, S., and Bijo Mathew, “Synthesis, Cytotoxicity and Anti-Proliferative Activity Against AGS Cells of New 3(2)-Pyridazinone Derivatives Endowed with a Piperazinyl Linker.”, Pharmaceuticals (Basel), Volume 14, Issue 3, 183, pp. 1-27 (2021)
Publisher : Basel
Year : 2021
Piperazine-substituted chalcones: a new class of MAO-B, AChE, and BACE-1 inhibitors for the treatment of neurological disorders
Cite this Research Publication : Bijo Mathew, Oh, J. Min, Baty, R. S., Batiha, G. El- Saber, Parambi, D. Grace Thom, Gambacorta, N., Nicolotti, O., and Kim, H., “Piperazine-substituted chalcones: a new class of MAO-B, AChE, and BACE-1 inhibitors for the treatment of neurological disorders”, Environmental Science and Pollution Research, 2021, 28(29), pp. 38855-38866.
Publisher : Environmental Science and Pollution Research
Year : 2021
Nanotechnology-Based Approaches and Investigational Therapeutics against COVID-19.
Cite this Research Publication : M. Mominur Rahman, Ahmed, M., Islam, M. Touhidul, Khan, M. Robin, Sultana, S., Maeesa, S. Kabir, Hasan, S., Hossain, M. Abid, Ferdous, K. Sayma, Bijo Mathew, Rauf, A., and Uddin, M. Sahab, “Nanotechnology-Based Approaches and Investigational Therapeutics against COVID-19.”, Current Pharmaceutical Design, 2021.
Publisher : Current Pharmaceutical Design
Year : 2021
Therapeutic Potential of Polyphenols in the Management of Diabetic Neuropathy.
Cite this Research Publication : M. Tanvir Kabir, Tabassum, N., Uddin, M. Sahab, Aziz, F., Behl, T., Bijo Mathew, Rahman, M. Habibur, Akter, R., Rauf, A., and Aleya, L., “Therapeutic Potential of Polyphenols in the Management of Diabetic Neuropathy.”, Evidence based Complementary and Alternative Medicine, vol. 2021, p. 9940169, 2021.
Publisher : Evidence based Complementary and Alternative Medicine
Year : 2021
Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach.
Cite this Research Publication : A. Sujathan Nair, Oh, J. - M., Koyiparambath, V. Payyalot, Sunil Kumar, Sudevan, S. Thazhathuv, Soremekun, O., Soliman, M. E., Khames, A., Abdelgawad, M. A., Pappachen, L. K., Bijo Mathew, and Kim, H., “Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach.”, Molecules, vol. 26, no. 11, 2021.
Publisher : Molecules
Year : 2021
Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development.
Cite this Research Publication : B. Meduri, Pujar, G. Veeranna, T Kumar, D. Ananda, Akshatha, H. S., Sethu, A. Kumar, Singh, M., Kanagarla, A., and Bijo Mathew, “Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development.”, Eur J Med Chem, vol. 222, p. 113574, 2021.
Publisher : ELSEVIER
Year : 2020
Design, Synthesis, and Biological Evaluation of Pyridazinones Containing the (2-Fluorophenyl) Piperazine Moiety as Selective MAO-B Inhibitors
Cite this Research Publication : M. Çeçen, Oh, J. Min, Özdemir, Z., Büyüktuncel, S. Ebru, Uysal, M., Abdelgawad, M. A., Musa, A., Gambacorta, N., Nicolotti, O., Mathew, B., and Kim, H., “Design, Synthesis, and Biological Evaluation of Pyridazinones Containing the (2-Fluorophenyl) Piperazine Moiety as Selective MAO-B Inhibitors.”, Molecules, vol. 25, no. 22, p. 5371, 2020.
Publisher : Molecules, Volume 25, Issue 22
Year : 2020
Natural Products Database Screening for the Discovery of Naturally Occurring SARS-Cov-2 Spike Glycoprotein Blockers
Cite this Research Publication : A. G. Al-Sehemi, Olotu, F. A., Dev, S., Pannipara, M., Soliman, M. E., Carradori, S., and Bijo Mathew, “Natural Products Database Screening for the Discovery of Naturally Occurring SARS-Cov-2 Spike Glycoprotein Blockers”, ChemistrySelect, vol. 5, pp. 13309-13317, 2020.
Publisher : ChemistrySelect
Year : 2020
(Hetero-)(arylidene)arylhydrazides as Multitarget-Directed Monoamine Oxidase Inhibitors
Cite this Research Publication : A. Palakkathondi, Oh, J. Min, Dev, S., Rangarajan, T. M., Kaipakasseri, S., Kavully, F. Sahla, Gambacorta, N., Nicolotti, O., Kim, H., and Bijo Mathew, “(Hetero-)(arylidene)arylhydrazides as Multitarget-Directed Monoamine Oxidase Inhibitors”, ACS Combinatorial ScienceACS Combinatorial Science, vol. 22, no. 11, pp. 592 - 599, 2020.
Publisher : American Chemical Society
Year : 2020
Chalcones: Unearthing their therapeutic possibility as monoamine oxidase B inhibitors
Cite this Research Publication : P. Guglielmi, Bijo Mathew, Secci, D., and Carradori, S., “Chalcones: Unearthing their therapeutic possibility as monoamine oxidase B inhibitors”, European Journal of Medicinal Chemistry, vol. 205, p. 112650, 2020.
Publisher : European Journal of Medicinal Chemistry
Year : 2020
Exploring the Therapeutic Potentials of Highly Selective Oxygenated Chalcone Based MAO-B Inhibitors in a Haloperidol-Induced Murine Model of Parkinson’s Disease
Cite this Research Publication : D. Grace Thom Parambi, Saleem, U., Shah, M. Ajmal, Anwar, F., Ahmad, B., Manzar, A., Itzaz, A., Harilal, S., Uddin, M. Sahab, Kim, H., and Bijo Mathew, “Exploring the Therapeutic Potentials of Highly Selective Oxygenated Chalcone Based MAO-B Inhibitors in a Haloperidol-Induced Murine Model of Parkinson’s Disease”, Neurochemical Research, vol. 45, no. 11, pp. 2786 - 2799, 2020.
Publisher : Neurochemical Research
Year : 2020
Natural compounds from Leeamacrophyllaenhance phagocytosis and promote osteoblastsdifferentiationbyAlp, Type 1 collagen and Osteocalcin gene expression.
Cite this Research Publication : S. Raiyan, Rahman, A., Mamun, A. Al, Asim, M. Haque, Makki, A., Hajjar, D., Alelwani, W., Tangpong, J., and Bijo Mathew, “Natural compounds from Leeamacrophyllaenhance phagocytosis and promote osteoblastsdifferentiationbyAlp, Type 1 collagen and Osteocalcin gene expression.”, Journal of Biomedical Materials Research Part A, 2020.
Publisher : Journal of Biomedical Materials Research Part A
Year : 2020
Selected 1,3-Benzodioxine-Containing Chalcones as Multipotent Oxidase and Acetylcholinesterase Inhibitors.
Cite this Research Publication : G. Seok Jeong, Kaipakasseri, S., Lee, S. Ryong, Marraiki, N., Batiha, G. El- Saber, Dev, S., Palakkathondi, A., Kavully, F. Sahla, Gambacorta, N., Nicolotti, O., Bijo Mathew, and Kim, H., “Selected 1,3-Benzodioxine-Containing Chalcones as Multipotent Oxidase and Acetylcholinesterase Inhibitors.”, ChemMedChem, vol. 15, pp. 2257-2263, 2020.
Publisher : ChemMedChem
Year : 2020
A New Potent and Selective Monoamine Oxidase-B Inhibitor with Extended Conjugation in a Chalcone Framework: 1-[4-(Morpholin-4-yl)phenyl]-5-phenylpenta-2,4-dien-1-one.
Cite this Research Publication : N. Maliyakkal, Eom, B. Hyun, Heo, J. Hyun, Almoyad, M. Ali Abdull, Parambi, D. Grace Thom, Gambacorta, N., Nicolotti, O., Beeran, A. Appadath, Kim, H., and Bijo Mathew, “A New Potent and Selective Monoamine Oxidase-B Inhibitor with Extended Conjugation in a Chalcone Framework: 1-[4-(Morpholin-4-yl)phenyl]-5-phenylpenta-2,4-dien-1-one.”, ChemMedChem, vol. 15, no. 17, pp. 1629-1633, 2020.
Publisher : ChemMedChem
Year : 2020
Molecular mechanism of zinc neurotoxicity in Alzheimer’s disease
Cite this Research Publication : S. Ellickal Narayanan, Rehuman, N. Abdul, Harilal, S., Vincent, A., Rajamma, R. Ganesan, Behl, T., Uddin, M. Sahab, Ashraf, G. Md, and Bijo Mathew, “Molecular mechanism of zinc neurotoxicity in Alzheimer’s disease”, Environ Sci Pollut Res, vol. 27, no. 35, pp. 43542 - 43552, 2020.
Publisher : Environ Sci Pollut Res
Year : 2020
Privileged Pharmacophore of FDA Approved Drugs in Combination with Chalcone Framework: A New Hope for Alzheimer’s Treatment.
Cite this Research Publication : Bijo Mathew, “Privileged Pharmacophore of FDA Approved Drugs in Combination with Chalcone Framework: A New Hope for Alzheimer's Treatment.”, Comb Chem High Throughput Screen, vol. 23, no. 9, pp. 842-846, 2020.
Publisher : Comb Chem High Throughput Screen
Year : 2020
Revisiting the role of brain and peripheral Aβ in the pathogenesis of Alzheimer’s disease
Cite this Research Publication : M. Sahab Uddin, Kabir, M. Tanvir, Tewari, D., Mamun, A. Al, Bijo Mathew, Aleya, L., Barreto, G. E., Bin-Jumah, M. N., Abdel-Daim, M. M., and Ashraf, G. Md, “Revisiting the role of brain and peripheral Aβ in the pathogenesis of Alzheimer's disease”, Journal of the Neurological Sciences, vol. 416, p. 116974, 2020.
Publisher : Journal of the Neurological Sciences
Year : 2020
Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer’s disease
Cite this Research Publication : M. Sahab Uddin, Rahman, M. Ataur, Kabir, M. Tanvir, Behl, T., Bijo Mathew, Perveen, A., Barreto, G. E., Bin-Jumah, M. N., Abdel-Daim, M. M., and Ashraf, G. Md, “Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer's disease.”, IUBMB Life, vol. 72, no. 9, pp. 1843-1855, 2020.
Publisher : IUBMB Life
Year : 2020
Synthesis and biological evaluation of new 3(2)-pyridazinone derivatives as non-toxic anti-proliferative compounds against human colon carcinoma HCT116 cells.
Cite this Research Publication : Z. Özdemir, Utku, S., Bijo Mathew, Carradori, S., Orlando, G., Di Simone, S., Alagöz, M. Abdullah, Özçelik, A. Berna, Uysal, M., and Ferrante, C., “Synthesis and biological evaluation of new 3(2)-pyridazinone derivatives as non-toxic anti-proliferative compounds against human colon carcinoma HCT116 cells.”, J Enzyme Inhib Med Chem, vol. 35, no. 1, pp. 1100-1109, 2020.
Publisher : J Enzyme Inhib Med Chem
Year : 2020
Inhibitions of monoamine oxidases and acetylcholinesterase by 1-methyl, 5-phenyl substituted thiosemicarbazones: Synthesis, biochemical, and computational investigations
Cite this Research Publication : G. Elizabeth Mathew, Oh, J. Min, Mohan, K., Kumudhavalli, M. V., Jayanthi, S., Kim, H., and Bijo Mathew, “Inhibitions of monoamine oxidases and acetylcholinesterase by 1-methyl, 5-phenyl substituted thiosemicarbazones: Synthesis, biochemical, and computational investigations”, Process Biochemistry, vol. 99, pp. 246-253, 2020.
Publisher : Process Biochemistry
Year : 2020
Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors.
Cite this Research Publication : J. Min Oh, Rangarajan, T. M., Chaudhary, R., Singh, R. Pal, Singh, M., Singh, R. Pal, Tondo, A. Rita, Gambacorta, N., Nicolotti, O., Bijo Mathew, and Kim, H., “Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors.”, Molecules, vol. 25, no. 10, 2020.
Publisher : Molecules
Year : 2020
Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules
Cite this Research Publication : S. Harilal, Jose, J., Parambi, D. Grace Thom, Kumar, R., Unnikrishnan, M. Kesavan, Uddin, M. Sahab, Mathew, G. Elizabeth, Pratap, R., Marathakam, A., and Bijo Mathew, “Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules”, Brain Research Bulletin, vol. 160, pp. 121-140, 2020.
Publisher : Brain Research Bulletin
Year : 2020
Novel Anti-Alzheimer’s Therapeutic Molecules Targeting Amyloid Precursor Protein Processing.
Cite this Research Publication : M. Sahab Uddin, Kabir, M. Tanvir, Jeandet, P., Bijo Mathew, Ashraf, G. Md, Perveen, A., Bin-Jumah, M. N., Mousa, S. A., and Abdel-Daim, M. M., “Novel Anti-Alzheimer's Therapeutic Molecules Targeting Amyloid Precursor Protein Processing.”, Oxid Med Cell Longev, vol. 2020, p. 7039138, 2020.
Publisher : Oxid Med Cell Longev
Year : 2020
Molecular Insight into the Therapeutic Promise of Targeting for Alzheimer’s Disease.
Cite this Research Publication : A. Al Mamun, Uddin, M. Sahab, Bin Bashar, M. Fahim, Zaman, S., Begum, Y., Bulbul, I. Jahan, Islam, M. Siddiqul, Sarwar, M. Shahid, Bijo Mathew, Amran, M. Shah, Ashraf, G. Md, Bin-Jumah, M. N., Mousa, S. A., and Abdel-Daim, M. M., “Molecular Insight into the Therapeutic Promise of Targeting for Alzheimer's Disease.”, Oxid Med Cell Longev, vol. 2020, p. 5086250, 2020.
Publisher : Oxid Med Cell Longev
Year : 2020
Design of enamides as new selective monoamine oxidase-B inhibitors
Cite this Research Publication : F. Sahla Kavully, Oh, J. Min, Dev, S., Kaipakasseri, S., Palakkathondi, A., Vengamthodi, A., Azeez, R. Fathima Ab, Tondo, A. Rita, Nicolotti, O., Kim, H., and Bijo Mathew, “Design of enamides as new selective monoamine oxidase-B inhibitors”, Journal of Pharmacy and Pharmacology, vol. 72, pp. 916-926, 2020.
Publisher : Journal of Pharmacy and Pharmacology
Year : 2020
Fascinating chemo preventive story of wogonin: A chance to hit on the head in cancer treatment.
Cite this Research Publication : R. Kumar, Harilal, S., Parambi, D. Grace Thom, Narayanan, S. E., Uddin, M. Sahab, Marathakam, A., Jose, J., Mathew, G. Elizabeth, and Bijo Mathew, “Fascinating chemo preventive story of wogonin: A chance to hit on the head in cancer treatment.”, Curr Pharm Des, 2020.
Publisher : Curr Pharm Des
Year : 2020
Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer’s Disease.
Cite this Research Publication : S. Ellickal Narayanan, Sekhar, N., Rajamma, R. Ganesan, Marathakam, A., Mamun, A. Al, Uddin, M. Sahab, and Bijo Mathew, “Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer's Disease.”, Curr Protein Pept Sci, vol. 21, no. 12, pp. 1164-1173, 2020.
Publisher : Curr Protein Pept Sci
Year : 2020
Combination Drug Therapy for the Management of Alzheimer’s Disease.
Cite this Research Publication : M. Tanvir Kabir, Uddin, M. Sahab, Mamun, A. Al, Jeandet, P., Aleya, L., Mansouri, R. A., Ashraf, G. Md, Bijo Mathew, Bin-Jumah, M. N., and Abdel-Daim, M. M., “Combination Drug Therapy for the Management of Alzheimer's Disease.”, Int J Mol Sci, vol. 21, no. 9, 2020.
Publisher : Int J Mol Sci
Year : 2020
Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer’s Disease.
Cite this Research Publication : M. Sahab Uddin, Kabir, M. Tanvir, Niaz, K., Jeandet, P., Clément, C., Bijo Mathew, Rauf, A., Rengasamy, K. R. R., Sobarzo-Sánchez, E., Ashraf, G. Md, and Aleya, L., “Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer's Disease.”, Molecules, vol. 25, no. 6, 2020.
Publisher : Molecules
Year : 2020
Emerging Promise of Immunotherapy for Alzheimer’s Disease: A New Hope for the Development of Alzheimer’s Vaccine.
Cite this Research Publication : M. Tanvir Kabir, Uddin, M. Sahab, Bijo Mathew, Das, P. Kumar, Perveen, A., and Ashraf, G. Md, “Emerging Promise of Immunotherapy for Alzheimer's Disease: A New Hope for the Development of Alzheimer's Vaccine.”, Curr Top Med Chem, vol. 20, no. 13, pp. 1214-1234, 2020.
Publisher : Curr Top Med Chem
Year : 2020
Estrogen Signaling in Alzheimer’s Disease: Molecular Insights and Therapeutic Targets for Alzheimer’s Dementia.
Cite this Research Publication : M. Sahab Uddin, Rahman, M. Motiar, Jakaria, M., Rahman, M. Sohanur, Hossain, M. Sarwar, Islam, A., Ahmed, M., Bijo Mathew, Omar, U. Mohammed, Barreto, G. E., and Ashraf, G. Md, “Estrogen Signaling in Alzheimer's Disease: Molecular Insights and Therapeutic Targets for Alzheimer's Dementia.”, Mol Neurobiol, vol. 57, no. 6, pp. 2654-2670, 2020.
Publisher : Mol Neurobiol
Year : 2020
Exploring the Multifunctional Neuroprotective Promise of Rasagiline Derivatives for Multi-Dysfunctional Alzheimer’s Disease.
Cite this Research Publication : M. Sahab Uddin, Kabir, M. Tanvir, Rahman, M. Habibur, Alim, M. Abdul, Rahman, M. Motiar, Khatkar, A., Mamun, A. Al, Rauf, A., Bijo Mathew, and Ashraf, G. Md, “Exploring the Multifunctional Neuroprotective Promise of Rasagiline Derivatives for Multi-Dysfunctional Alzheimer's Disease.”, Curr Pharm Des, vol. 26, no. 37, pp. 4690-4698, 2020.
Publisher : Curr Pharm Des
Year : 2020
Exploring the Promise of Targeting Ubiquitin-Proteasome System to Combat Alzheimer’s Disease.
Cite this Research Publication : A. Al Mamun, Uddin, M. Sahab, Kabir, M. Tanvir, Khanum, S., Sarwar, M. Shahid, Bijo Mathew, Rauf, A., Ahmed, M., and Ashraf, G. Md, “Exploring the Promise of Targeting Ubiquitin-Proteasome System to Combat Alzheimer's Disease.”, Neurotox Res, vol. 38, no. 1, pp. 8-17, 2020.
Publisher : Neurotox Res
Year : 2020
TV 3326 for Alzheimer’s dementia: a novel multimodal ChE and MAO inhibitors to mitigate Alzheimer’s-like neuropathology
Cite this Research Publication : M. Sahab Uddin, Kabir, M. Tanvir, Rahman, M. Motiar, Bijo Mathew, Shah, M. Ajmal, and Ashraf, G. Md, “TV 3326 for Alzheimer’s dementia: a novel multimodal ChE and MAO inhibitors to mitigate Alzheimer’s-like neuropathology”, Journal of Pharmacy and Pharmacology, vol. 72, pp. 1001-1012, 2020.
Publisher : Journal of Pharmacy and Pharmacology
Year : 2020
Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety.
Cite this Research Publication : M. M. Al-Sanea, Gotina, L., Mohamed, M. Fa, Parambi, D. Grace Thom, Gomaa, H. A. M., Bijo Mathew, Youssif, B. G. M., Alharbi, K. Saad, Elsayed, Z. M., Abdelgawad, M. A., and Eldehna, W. M., “Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety.”, Drug Des Devel Ther, vol. 14, pp. 497-508, 2020.
Publisher : Drug Des Devel Ther
Year : 2020
A Comprehensive Review of Monoamine Oxidase-A Inhibitors in their Syntheses and Potencies.
Cite this Research Publication : N. A. Rehuman, Bijo Mathew, Jat, R. K., Nicolotti, O., and Kim, H., “A Comprehensive Review of Monoamine Oxidase-A Inhibitors in their Syntheses and Potencies.”, Comb Chem High Throughput Screen, vol. 23, no. 9, pp. 898-914, 2020.
Publisher : Comb Chem High Throughput Screen
Year : 2020
Magnetic nanoparticles for hyperthermia in cancer treatment: an emerging tool.
Cite this Research Publication : J. Jose, Kumar, R., Harilal, S., Mathew, G. Elizabeth, Parambi, D. Grace Thom, Prabhu, A., Uddin, M. Sahab, Aleya, L., Kim, H., and Bijo Mathew, “Magnetic nanoparticles for hyperthermia in cancer treatment: an emerging tool.”, Environ Sci Pollut Res Int, vol. 27, no. 16, pp. 19214-19225, 2020.
Publisher : Environ Sci Pollut Res Int
Year : 2020
Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer’s disease.
Cite this Research Publication : M. Sahab Uddin, Kabir, M. Tanvir, Tewari, D., Bijo Mathew, and Aleya, L., “Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer's disease.”, Sci Total Environ, vol. 700, p. 134836, 2020.
Publisher : Sci Total Environ
Year : 2020
Toxic tau: structural origins of tau aggregation in Alzheimer’s disease.
Cite this Research Publication : A. Al Mamun, Uddin, M. Sahab, Bijo Mathew, and Ashraf, G. Md, “Toxic tau: structural origins of tau aggregation in Alzheimer's disease.”, Neural Regen Res, vol. 15, no. 8, pp. 1417-1420, 2020.
Publisher : Neural Regen Res
Year : 2020
Emerging promise of sulforaphane-mediated Nrf2 signaling cascade against neurological disorders.
Cite this Research Publication : M. Sahab Uddin, Mamun, A. Al, Jakaria, M., Thangapandiyan, S., Ahmad, J., Rahman, M. Ataur, Bijo Mathew, Abdel-Daim, M. M., and Aleya, L., “Emerging promise of sulforaphane-mediated Nrf2 signaling cascade against neurological disorders.”, Sci Total Environ, vol. 707, p. 135624, 2020.
Publisher : Sci Total Environ
Year : 2020
Studies on the interaction between HSA and new halogenated metformin derivatives: influence of lipophilic groups in the binding ability.
Cite this Research Publication : O. Augusto Chaves, Bijo Mathew, Parambi, D. Grace Thom, de Oliveira, C. Henrique C., Cesarin-Sobrinho, D., Lakshminarayanan, B., Najeeb, S., Nafna, E. K., Marathakam, A., Uddin, M. Sahab, Joy, M., and Netto-Ferreira, J. Carlos, “Studies on the interaction between HSA and new halogenated metformin derivatives: influence of lipophilic groups in the binding ability.”, J Biomol Struct Dyn, vol. 38, no. 7, pp. 2128-2140, 2020.
Publisher : J Biomol Struct Dyn
Year : 2020
Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery.
Cite this Research Publication : N. Zahin, Anwar, R., Tewari, D., Kabir, M. Tanvir, Sajid, A., Bijo Mathew, Uddin, M. Sahab, Aleya, L., and Abdel-Daim, M. M., “Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery.”, Environ Sci Pollut Res Int, vol. 27, no. 16, pp. 19151-19168, 2020.
Publisher : Environ Sci Pollut Res Int
Year : 2020
An Environment-friendly Synthesis of Piperonal Chalcones and Their Cytotoxic and Antioxidant Evaluation
Cite this Research Publication : S. Dev, Parambi, D. Grace Thom, Baby, B., Mathew, G. Elizabeth, Magdy, H. Omnia, Joy, M., Sudev, S., and Bijo Mathew, “An Environment-friendly Synthesis of Piperonal Chalcones and Their Cytotoxic and Antioxidant Evaluation”, Letters in Drug Design & Discovery, vol. 17, pp. 138-144, 2020.
Publisher : Letters in Drug Design & Discovery
Year : 2020
Inhibitors of Monoamine Oxidase and Acetylcholinesterase as a Front Runner in CNS Drug Discovery
Cite this Research Publication : Bijo Mathew and Kim, H., “Inhibitors of Monoamine Oxidase and Acetylcholinesterase as a Front Runner in CNS Drug Discovery.”, Comb Chem High Throughput Screen, vol. 23, no. 9, pp. 834-835, 2020.
Publisher : Comb Chem High Throughput Screen
Year : 2019
Design, synthesis and biological evaluation of oxygenated chalcones as potent and selective MAO-B inhibitors.
Cite this Research Publication : D. Grace Thom Parambi, Oh, J. Min, Baek, S. Cheol, Lee, J. Pil, Tondo, A. Rita, Nicolotti, O., Kim, H., and Bijo Mathew, “Design, synthesis and biological evaluation of oxygenated chalcones as potent and selective MAO-B inhibitors.”, Bioorg Chem, vol. 93, p. 103335, 2019.
Publisher : Bioorg Chem
Year : 2019
Exploring the new horizons of drug repurposing: A vital tool for turning hard work into smart work.
Cite this Research Publication : R. Kumar, Harilal, S., Gupta, S. Varghese, Jose, J., Parambi, D. Grace Thom, Uddin, M. Sahab, Shah, M. Ajmal, and Bijo Mathew, “Exploring the new horizons of drug repurposing: A vital tool for turning hard work into smart work.”, Eur J Med Chem, vol. 182, p. 111602, 2019.
Publisher : Eur J Med Chem
Year : 2019
Anti-inflammatory effect of synthesized indole-based chalcone (2E)-3-(4-bromophenyl)-1-(1-indol-3-yl) prop-2-en-1-one: an and studies.
Cite this Research Publication : R. Sasidharan, Leelabaiamma, M. Sreedharan, Mohanan, R., Jose, S. P., Bijo Mathew, and Sukumaran, S., “Anti-inflammatory effect of synthesized indole-based chalcone (2E)-3-(4-bromophenyl)-1-(1-indol-3-yl) prop-2-en-1-one: an and studies.”, Immunopharmacol Immunotoxicol, vol. 41, no. 6, pp. 568-576, 2019.
Publisher : Immunopharmacol Immunotoxicol
Year : 2019
Emerging therapeutic potentials of dual-acting MAO and AChE inhibitors in Alzheimer’s and Parkinson’s diseases.
Cite this Research Publication : Bijo Mathew, Parambi, D. G. T., Mathew, G. E., Uddin, M. Sahab, Inasu, S. T., Kim, H., Marathakam, A., Unnikrishnan, M. Kesavan, and Carradori, S., “Emerging therapeutic potentials of dual-acting MAO and AChE inhibitors in Alzheimer's and Parkinson's diseases.”, Arch Pharm (Weinheim), vol. 352, no. 11, p. e1900177, 2019.
Publisher : Arch Pharm (Weinheim)
Year : 2019
Ethyl Acetohydroxamate Incorporated Chalcones: Unveiling a Novel Class of Chalcones for Multitarget Monoamine Oxidase-B Inhibitors Against Alzheimer’s Disease.
Cite this Research Publication : S. Cheol Baek, Lee, J. Pil, Rangarajan, T. M., Singh, R. Pal, Singh, M., Mangiatordi, G. Felice, Nicolotti, O., Kim, H., and Bijo Mathew, “Ethyl Acetohydroxamate Incorporated Chalcones: Unveiling a Novel Class of Chalcones for Multitarget Monoamine Oxidase-B Inhibitors Against Alzheimer's Disease.”, CNS Neurol Disord Drug Targets, vol. 18, no. 8, pp. 643-654, 2019.
Publisher : CNS Neurol Disord Drug Targets
Year : 2019
NMDA Receptor Antagonists: Repositioning of Memantine as a Multitargeting Agent for Alzheimer’s Therapy.
Cite this Research Publication : M. Tanvir Kabir, Sufian, M. A., Uddin, M. Sahab, Begum, M. Marium, Akhter, S., Islam, A., Bijo Mathew, Islam, M. Siddiqul, Amran, M. Shah, and Ashraf, G. Md, “NMDA Receptor Antagonists: Repositioning of Memantine as a Multitargeting Agent for Alzheimer's Therapy.”, Curr Pharm Des, vol. 25, no. 33, pp. 3506-3518, 2019.
Publisher : Curr Pharm Des
Year : 2019
Cholinesterase Inhibitors for Alzheimer’s Disease: Multitargeting Strategy Based on Anti-Alzheimer’s Drugs Repositioning.
Cite this Research Publication : M. Tanvir Kabir, Uddin, M. Sahab, Begum, M. Marium, Thangapandiyan, S., Rahman, M. Sohanur, Aleya, L., Bijo Mathew, Ahmed, M., Barreto, G. E., and Ashraf, G. Md, “Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning.”, Curr Pharm Des, vol. 25, no. 33, pp. 3519-3535, 2019.
Publisher : Curr Pharm Des
Year : 2019
Aptamers in Drug Design: An Emerging Weapon to Fight a Losing Battle.
Cite this Research Publication : J. Jose, Thomas, A. Mathew, Mendonsa, D., Al-Sanea, M. M., Uddin, M. Sahab, Parambi, D. Grace Thom, R Charyulu, N., and Bijo Mathew, “Aptamers in Drug Design: An Emerging Weapon to Fight a Losing Battle.”, Curr Drug Targets, vol. 20, no. 16, pp. 1624-1635, 2019.
Publisher : Curr Drug Targets
Year : 2019
Advancements in nanotherapeutics for Alzheimer’s disease: current perspectives.
Cite this Research Publication : S. Harilal, Jose, J., Parambi, D. Grace Thom, Kumar, R., Mathew, G. Elizabeth, Uddin, M. Sahab, Kim, H., and Bijo Mathew, “Advancements in nanotherapeutics for Alzheimer's disease: current perspectives.”, J Pharm Pharmacol, vol. 71, no. 9, pp. 1370-1383, 2019.
Publisher : J Pharm Pharmacol
Year : 2019
Melatonin in Alzheimer’s Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer’s Neuropathology
Cite this Research Publication : M. Farhad Hossain, Uddin, M. Sahab, Uddin, G. M. Sala, Sumsuzzman, D. Md, Islam, M. Siddiqul, Barreto, G. E., Bijo Mathew, and Ashraf, G. Md, “Melatonin in Alzheimer's Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer's Neuropathology.”, Mol Neurobiol, vol. 56, no. 12, pp. 8255-8276, 2019.
Publisher : Mol Neurobiol
Year : 2019
Natural inhibitors on airway mucin: Molecular insight into the therapeutic potential targeting MUC5AC expression and production.
Cite this Research Publication : M. Samsuzzaman, Uddin, M. Sahab, Shah, M. Ajmal, and Bijo Mathew, “Natural inhibitors on airway mucin: Molecular insight into the therapeutic potential targeting MUC5AC expression and production.”, Life Sci, vol. 231, p. 116485, 2019.
Publisher : Life Sci
Year : 2019
Ethoxylated Head of Chalcones as a New Class of Multi-Targeted MAO Inhibitors
Cite this Research Publication : B. Lakshminarayanan, Baek, S. Cheol, Lee, J. Pil, Kannappan, N., Mangiatordi, G. Felice, Nicolotti, O., Subburaju, T., Kim, H., and Bijo Mathew, “Ethoxylated Head of Chalcones as a New Class of Multi-Targeted MAO Inhibitors”, ChemistrySelect, vol. 4, pp. 6614-6619, 2019.
Publisher : ChemistrySelect
Year : 2019
Perspective Design of Chalcones for the Management of CNS Disorders: A Mini-Review.
Cite this Research Publication : Bijo Mathew, Parambi, D. Grace Thom, Sivasankarapillai, V. Sankar, Uddin, M. Sahab, Suresh, J., Mathew, G. Elizabeth, Joy, M., Marathakam, A., and Gupta, S. Varghese, “Perspective Design of Chalcones for the Management of CNS Disorders: A Mini-Review.”, CNS Neurol Disord Drug Targets, vol. 18, no. 6, pp. 432-445, 2019.
Publisher : CNS Neurol Disord Drug Targets
Year : 2019
Silicon Quantum Dots: Promising Theranostic Probes for the Future.
Cite this Research Publication : V. Sankar Sivasankarapillai, Jose, J., Shanavas, M. Salman, Marathakam, A., Uddin, M. Sahab, and Bijo Mathew, “Silicon Quantum Dots: Promising Theranostic Probes for the Future.”, Curr Drug Targets, vol. 20, no. 12, pp. 1255-1263, 2019.
Publisher : Curr Drug Targets
Year : 2019
In Vitro Study of the Interaction Between HSA and 4-Bromoindolylchalcone, a Potent Human MAO-B Inhibitor: Spectroscopic and Molecular Modeling Studies
Cite this Research Publication : O. Augusto Chaves, Sasidharan, R., de Oliveira, C. H. C. dos, Manju, S. Leelabaiam, Joy, M., Bijo Mathew, and Netto-Ferreira, J. Carlos, “In Vitro Study of the Interaction Between HSA and 4-Bromoindolylchalcone, a Potent Human MAO-B Inhibitor: Spectroscopic and Molecular Modeling Studies”, ChemistrySelect, vol. 4, pp. 1007-1014, 2019.
Publisher : ChemistrySelect
Year : 2019
Potent and highly selective dual-targeting monoamine oxidase-B inhibitors: Fluorinated chalcones of morpholine versus imidazole
Cite this Research Publication : Bijo Mathew, Baek, S. C., Parambi, D. G. Thomas, Lee, J. P., Mathew, G. E., Jayanthi, S., Vinod, D., Rapheal, C., Devikrishna, V., Kondarath, S. Shad, Uddin, M. Sahab, and Kim, H., “Potent and highly selective dual-targeting monoamine oxidase-B inhibitors: Fluorinated chalcones of morpholine versus imidazole.”, Arch Pharm (Weinheim), vol. 352, no. 4, p. e1800309, 2019.
Publisher : Arch Pharm (Weinheim)
Year : 2019
Fe O nanoparticles mediated synthesis of novel spirooxindole-dihydropyrimidinone molecules as Hsp90 inhibitors.
Cite this Research Publication : S. Maddela, Makula, A., Galigniana, M. D., Parambi, D. G. T., Federicci, F., Mazaira, G., Hendawy, O. M., Dev, S., Mathew, G. E., and Bijo Mathew, “Fe O nanoparticles mediated synthesis of novel spirooxindole-dihydropyrimidinone molecules as Hsp90 inhibitors.”, Arch Pharm (Weinheim), vol. 352, no. 1, p. e1800174, 2019.
Publisher : Arch Pharm (Weinheim)
Year : 2019
Cholinesterase Inhibitory Activities of Selected Halogenated Thiophene Chalcones.
Cite this Research Publication : D. G. T. Parambi, Aljoufi, F., Murugaiyah, V., Mathew, G. E., Dev, S., Lakshminarayanan, B., Hendawy, O. M., and Bijo Mathew, “Cholinesterase Inhibitory Activities of Selected Halogenated Thiophene Chalcones.”, Cent Nerv Syst Agents Med Chem, vol. 19, no. 1, pp. 67-71, 2019.
Publisher : Cent Nerv Syst Agents Med Chem
Year : 2019
Unraveling the Structural Requirements of Chalcone Chemistry Towards Monoamine Oxidase Inhibition.
Cite this Research Publication :
Publisher : Cent Nerv Syst Agents Med Chem
Year : 2019
Nootropic and Anti-Alzheimer’s Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer’s Neuropathology
Cite this Research Publication : M. Sahab Uddin, Mamun, A. Al, Kabir, M. Tanvir, Jakaria, M., Bijo Mathew, Barreto, G. E., and Ashraf, G. Md, “Nootropic and Anti-Alzheimer's Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer's Neuropathology.”, Mol Neurobiol, vol. 56, no. 7, pp. 4925-4944, 2019.
Publisher : Mol Neurobiol
Year : 2018
Dual acting Isatin-Heterocyclic Hybrids: Recent Highlights as Promising Pharmacological Agents
Cite this Research Publication : Bijo Mathew, “Dual acting Isatin-Heterocyclic Hybrids: Recent Highlights as Promising Pharmacological Agents”, vol. 15, 2018.
Publisher : Volume 15
Year : 2018
Selected aryl thiosemicarbazones as a new class of multi-targeted monoamine oxidase inhibitors.
Cite this Research Publication : Bijo Mathew, Baek, S. Cheol, Parambi, D. Grace Thom, Lee, J. Pil, Joy, M., Rilda, P. R. Annie, Randev, R. V., Nithyamol, P., Vijayan, V., Inasu, S. T., Mathew, G. Elizabeth, Lohidakshan, K. K., Krishnan, G. Kumar, and Kim, H., “Selected aryl thiosemicarbazones as a new class of multi-targeted monoamine oxidase inhibitors.”, Medchemcomm, vol. 9, no. 11, pp. 1871-1881, 2018.
Publisher : Medchemcomm
Year : 2018
Imidazole bearing chalcones as a new class of monoamine oxidase inhibitors.
Cite this Research Publication : R. Sasidharan, Baek, S. Cheol, Leelabaiamma, M. Sreedharan, Kim, H., and Bijo Mathew, “Imidazole bearing chalcones as a new class of monoamine oxidase inhibitors.”, Biomed Pharmacother, vol. 106, pp. 8-13, 2018.
Publisher : Biomed Pharmacothe
Year : 2018
Structural and optical profile of a multifunctionalized 2-pyridone derivative in a crystal engineering perspective.
Cite this Research Publication : M. Joy, Anabha, E. R., Gopi, S., Bijo Mathew, S, A. Kumar, and Mathews, A., “Structural and optical profile of a multifunctionalized 2-pyridone derivative in a crystal engineering perspective.”, Acta Crystallogr C Struct Chem, vol. 74, no. Pt 7, pp. 807-815, 2018.
Publisher : Acta Crystallogr C Struct Chem
Year : 2018
Introduction of fluorinated environment on metformin. Evaluation of its serum-albumin interaction with molecular modeling studies
Cite this Research Publication : O. Augusto Chaves, Bijo Mathew, Joy, M., Lohidakshan, K. K., Marathakam, A., and Netto-Ferreira, J. Carlos, “Introduction of fluorinated environment on metformin. Evaluation of its serum-albumin interaction with molecular modeling studies”, Journal of Molecular Liquids, vol. 260, pp. 186-194, 2018.
Publisher : Journal of Molecular Liquids
Year : 2018
Discovery of potent and reversible MAO-B inhibitors as furanochalcones
Cite this Research Publication : J. Suresh, Baek, S. Cheol, Ramakrishnan, S. Parakkot, Kim, H., and Bijo Mathew, “Discovery of potent and reversible MAO-B inhibitors as furanochalcones”, International Journal of Biological Macromolecules, vol. 108, pp. 660-664, 2018.
Publisher : International Journal of Biological Macromolecules
Year : 2018
Discovery of new class of methoxy carrying isoxazole derivatives as COX-II inhibitors: Investigation of a detailed molecular dynamics study
Cite this Research Publication : M. Joy, Elrashedy, A. A., Bijo Mathew, Pillay, A. Singh, Mathews, A., Dev, S., Soliman, M. E. S., and Sudarsanakumar, C., “Discovery of new class of methoxy carrying isoxazole derivatives as COX-II inhibitors: Investigation of a detailed molecular dynamics study”, Journal of Molecular Structure, vol. 1157, pp. 19-28, 2018.
Publisher : Journal of Molecular Structure
Year : 2018
Virtual combinatorial library design, synthesis and in vitro anticancer assessment of -2-amino-3-cyanopyridine derivatives
Cite this Research Publication : D. S., ,, and Bijo Mathew, “Virtual combinatorial library design, synthesis and in vitro anticancer assessment of -2-amino-3-cyanopyridine derivatives”, Combinatorial Chemistry and High Throughput Screening. [Bentham Science], vol. 21, pp. 138-148, 2018.
Publisher : Combinatorial Chemistry and High Throughput Screening. [Bentham Science]
Year : 2018
Structural features of Safinamide: A combined Hirshfeld surface analysis & quantum chemical treatment
Cite this Research Publication : M. Joy, Bijo Mathew, and Sudarsanakumar, C., “Structural features of Safinamide: A combined Hirshfeld surface analysis & quantum chemical treatment”, Chemical Data Collections, vol. 17-18, pp. 404-414, 2018.
Publisher : Chemical Data Collections
Year : 2017
Pharmacophore-Based 3D-QSAR Analysis of Thienyl Chalcones as a New Class of Human MAO-B Inhibitors: Investigation of Combined Quantum Chemical and Molecular Dynamics Approach.
Cite this Research Publication : Bijo Mathew, Adeniyi, A. A., Dev, S., Joy, M., Ucar, G., Mathew, G. Elizabeth, Singh-Pillay, A., and Soliman, M. E. S., “Pharmacophore-Based 3D-QSAR Analysis of Thienyl Chalcones as a New Class of Human MAO-B Inhibitors: Investigation of Combined Quantum Chemical and Molecular Dynamics Approach.”, J Phys Chem B, vol. 121, no. 6, pp. 1186-1203, 2017.
Publisher : J Phys Chem B
Year : 2017
Spectroscopic, zeta potential and molecular docking analysis on the interaction between human serum albumin and halogenated thienyl chalcones
Cite this Research Publication : O. Augusto Chaves, Bijo Mathew, Cesarin-Sobrinho, D., Lakshminarayanan, B., Joy, M., Mathew, G. Elizabeth, Suresh, J., and Netto-Ferreira, J. Carlos, “Spectroscopic, zeta potential and molecular docking analysis on the interaction between human serum albumin and halogenated thienyl chalcones”, Journal of Molecular Liquids, vol. 242, pp. 1018-1026, 2017.
Publisher : Journal of Molecular Liquids
Year : 2017
Monoamine oxidase inhibitory activity of methoxy-substituted chalcones.
Cite this Research Publication : Bijo Mathew, Mathew, G. Elizabeth, Ucar, G., Joy, M., Nafna, E. K., Lohidakshan, K. K., and Suresh, J., “Monoamine oxidase inhibitory activity of methoxy-substituted chalcones.”, Int J Biol Macromol, vol. 104, no. Pt A, pp. 1321-1329, 2017.
Publisher : Int J Biol Macromol
Year : 2017
Synthetic Approaches to Various Class of Topoisomerase II Inhibitors
Cite this Research Publication : S. Dev, Gabhe, N., Dhaneshwar, S. R., Joy, M., and Bijo Mathew, “Synthetic Approaches to Various Class of Topoisomerase II Inhibitors”, Mini-Reviews in Organic Chemistry, vol. 14, pp. 357-374, 2017.
Publisher : Mini-Reviews in Organic Chemistry
Year : 2017
Molecular modeling of drug-pathophysiological Mtb protein targets: Synthesis of some 2-thioxo-1, 3-thiazolidin-4-one derivatives as anti-tubercular agents
Cite this Research Publication : K. M. Noorulla, Suresh, A. Jerad, Devaraji, V., Bijo Mathew, and Umesh, D., “Molecular modeling of drug-pathophysiological Mtb protein targets: Synthesis of some 2-thioxo-1, 3-thiazolidin-4-one derivatives as anti-tubercular agents”, Journal of Molecular Structure, vol. 1147, pp. 682-696, 2017.
Publisher : Journal of Molecular Structure
Year : 2017
Anti-oxidant behavior of functionalized chalcone-a combined quantum chemical and crystallographic structural investigation
Cite this Research Publication : Bijo Mathew, Adeniyi, A. A., Joy, M., Mathew, G. Elizabeth, Singh-Pillay, A., Sudarsanakumar, C., Soliman, M. E. S., and Suresh, J., “Anti-oxidant behavior of functionalized chalcone-a combined quantum chemical and crystallographic structural investigation”, Journal of Molecular Structure, vol. 1146, pp. 301-308, 2017.
Publisher : Journal of Molecular Structure
Year : 2017
Probing mechanism of α-formylketene dithioacetal towards the facile formation of functionalized pyrimidines: A structural approach
Cite this Research Publication : M. Joy, Adeniyi, A. A., Mathews, A., Bijo Mathew, Prasanth, S., Soliman, M. E. S., Malayan, J. J., and Anabha, E. R., “Probing mechanism of α-formylketene dithioacetal towards the facile formation of functionalized pyrimidines: A structural approach”, Journal of Molecular Structure, vol. 1127, pp. 498-510, 2017.
Publisher : Journal of Molecular Structure
Year : 2017
Structural Exploration of Synthetic Chromones as Selective MAO-B Inhibitors: A Mini Review.
Cite this Research Publication : Bijo Mathew, Mathew, G. Elizabeth, Petzer, J. P., and Petzer, A., “Structural Exploration of Synthetic Chromones as Selective MAO-B Inhibitors: A Mini Review.”, Comb Chem High Throughput Screen, vol. 20, no. 6, pp. 522-532, 2017.
Publisher : Comb Chem High Throughput Screen
Year : 2017
Molecular Docking, Synthesis and CNS Activity of Some Novel 1, 4-Benzodiazepine Derivatives
Cite this Research Publication : S. S. Menghani*, Chikhale, R., Pant, A., Bijo Mathew, and Khedekar, P., “Molecular Docking, Synthesis and CNS Activity of Some Novel 1, 4-Benzodiazepine Derivatives”, 2017.
Year : 2017
Characterization of Thienylchalcones as hMAO-B Inhibitors: Synthesis, Biochemistry and Molecular Dynamics Studies
Cite this Research Publication : Bijo Mathew, Ucar, G., Rapheal, C., Mathew, G. E., Joy, M., Machaba, K. E., and Soliman, M. E. S., “Characterization of Thienylchalcones as hMAO-B Inhibitors: Synthesis, Biochemistry and Molecular Dynamics Studies”, ChemistrySelect, vol. 2, pp. 11113-11119, 2017.
Publisher : ChemistrySelect, Volume 2
Year : 2017
Refining the Structural Features of Chromones as Selective MAO-B Inhibitors: Exploration of Combined Pharmacophore-Based 3D-QSAR and Quantum Chemical Studies
Cite this Research Publication : Bijo Mathew, Dev, S., Joy, M., Mathew, G. E., Marathakam, A., and Krishnan, G. K., “Refining the Structural Features of Chromones as Selective MAO-B Inhibitors: Exploration of Combined Pharmacophore-Based 3D-QSAR and Quantum Chemical Studies”, ChemistrySelectChemistrySelectChemistrySelect, vol. 2, no. 35, pp. 11645 - 11652, 2017.
Publisher : John Wiley & Sons, Ltd
Year : 2016
Ligand based drug design of new heterocyclic imines of GABA analogues: A molecular docking approach for the discovery of new GABA-AT inhibitors.
Cite this Research Publication : Bijo Mathew, Mathew, G. Elizabeth, Suresh, J., Usman, D., Subramanyan, P. Natarajan, and Safna, K. Fathima, “Ligand based drug design of new heterocyclic imines of GABA analogues: A molecular docking approach for the discovery of new GABA-AT inhibitors.”, Cent Nerv Syst Agents Med Chem, 2016.
Publisher : Cent Nerv Syst Agents Med Chem
Year : 2016
Monoamine Oxidase Inhibitory Activity: Methyl- versus Chlorochalcone Derivatives.
Cite this Research Publication : Bijo Mathew, Ucar, G., Mathew, G. Elizabeth, Mathew, S., Purapurath, P. Kalatharak, Moolayil, F., Mohan, S., and Gupta, S. Varghese, “Monoamine Oxidase Inhibitory Activity: Methyl- versus Chlorochalcone Derivatives.”, ChemMedChem, vol. 11, no. 24, pp. 2649-2655, 2016.
Publisher : ChemMedChem
Year : 2016
Discovery of Camptothecin Based Topoisomerase I Inhibitors: Identification Using an Atom Based 3D-QSAR, Pharmacophore Modeling, Virtual Screening and Molecular Docking Approach.
Cite this Research Publication : S. Dev, Dhaneshwar, S. R., and Bijo Mathew, “Discovery of Camptothecin Based Topoisomerase I Inhibitors: Identification Using an Atom Based 3D-QSAR, Pharmacophore Modeling, Virtual Screening and Molecular Docking Approach.”, Comb Chem High Throughput Screen, vol. 19, no. 9, pp. 752-763, 2016.
Publisher : Comb Chem High Throughput Screen
Year : 2016
Identification of Indole-Based Chalcones: Discovery of a Potent, Selective, and Reversible Class of MAO-B Inhibitors.
Cite this Research Publication : R. Sasidharan, Manju, S. Leelabaiam, Ucar, G., Baysal, I., and Bijo Mathew, “Identification of Indole-Based Chalcones: Discovery of a Potent, Selective, and Reversible Class of MAO-B Inhibitors.”, Arch Pharm (Weinheim), vol. 349, no. 8, pp. 627-37, 2016.
Publisher : Arch Pharm (Weinheim)
Year : 2016
Exploration of chlorinated thienyl chalcones: A new class of monoamine oxidase-B inhibitors.
Cite this Research Publication : Bijo Mathew, Haridas, A., Ucar, G., Baysal, I., Adeniyi, A. A., Soliman, M. E. S., Joy, M., Mathew, G. Elizabeth, Lakshmanan, B., and Jayaprakash, V., “Exploration of chlorinated thienyl chalcones: A new class of monoamine oxidase-B inhibitors.”, Int J Biol Macromol, vol. 91, pp. 680-95, 2016.
Publisher : Int J Biol Macromol
Year : 2016
Synthesis, Biochemistry, and Computational Studies of Brominated Thienyl Chalcones: A New Class of Reversible MAO-B Inhibitors.
Cite this Research Publication : Bijo Mathew, Haridas, A., Ucar, G., Baysal, I., Joy, M., Mathew, G. E., Lakshmanan, B., and Jayaprakash, V., “Synthesis, Biochemistry, and Computational Studies of Brominated Thienyl Chalcones: A New Class of Reversible MAO-B Inhibitors.”, ChemMedChem, vol. 11, no. 11, pp. 1161-71, 2016.
Publisher : ChemMedChem
Year : 2016
Potent and Selective Monoamine Oxidase-B Inhibitory Activity: Fluoro- vs. Trifluoromethyl-4-hydroxylated Chalcone Derivatives.
Cite this Research Publication : Bijo Mathew, Mathew, G. Elizabeth, Ucar, G., Baysal, I., Suresh, J., Mathew, S., Haridas, A., and Jayaprakash, V., “Potent and Selective Monoamine Oxidase-B Inhibitory Activity: Fluoro- vs. Trifluoromethyl-4-hydroxylated Chalcone Derivatives.”, Chem Biodivers, vol. 13, no. 8, pp. 1046-52, 2016.
Publisher : Chem Biodivers
Year : 2016
Discovery of some novel imines of 2-amino, 5-thio, 1,3,4-thiadiazole as mucomembranous protector. Synthesis, anti-oxidant activity and in silico PASS approach
Cite this Research Publication : Bijo Mathew, Suresh, J., Anbazhagan, S., and Chidambaranathan, N., “Discovery of some novel imines of 2-amino, 5-thio, 1,3,4-thiadiazole as mucomembranous protector. Synthesis, anti-oxidant activity and in silico PASS approach”, Journal of Saudi Chemical Society, vol. 20, pp. S426-S432, 2016.
Publisher : Journal of Saudi Chemical Society
Year : 2016
Development of novel (1-H) benzimidazole bearing pyrimidine-trione based MAO-A inhibitors: Synthesis, docking studies and antidepressant activity
Cite this Research Publication : Bijo Mathew, Suresh, J., and Anbazhagan, S., “Development of novel (1-H) benzimidazole bearing pyrimidine-trione based MAO-A inhibitors: Synthesis, docking studies and antidepressant activity”, Journal of Saudi Chemical Society, vol. 20, pp. S132-S139, 2016.
Publisher : Journal of Saudi Chemical Society
Year : 2016
Monoamine Oxidase Inhibitors: Perspective Design for the Treatment of Depression and Neurological Disorders
Cite this Research Publication : Bijo Mathew, Mathew, G. E., Suresh, J., Ucar, G., Sasidharan, R., Anbazhagan, S., and Jayaprakash, J. K. Vilapur, “Monoamine Oxidase Inhibitors: Perspective Design for the Treatment of Depression and Neurological Disorders”, 2016.
Year : 2016
Monoamine Oxidase Inhibitory Action of Chalcones: A Mini Review.
Cite this Research Publication : Bijo Mathew, Haridas, A., Suresh, J., Mathew, G. E., Ucar, G., and Jayaprakash, V., “Monoamine Oxidase Inhibitory Action of Chalcones: A Mini Review.”, Cent Nerv Syst Agents Med Chem, vol. 16, no. 2, pp. 120-36, 2016.
Publisher : Cent Nerv Syst Agents Med Chem
Year : 2016
Pharmacophore Modeling, 3D-QSAR and Molecular Docking of Furanochalcones as Inhibitors of Monoamine Oxidase-B.
Cite this Research Publication : Bijo Mathew, Dev, S., Suresh, J., Mathew, G. E., Lakshmanan, B., Haridas, A., Fathima, F., and Krishnan, G. K., “Pharmacophore Modeling, 3D-QSAR and Molecular Docking of Furanochalcones as Inhibitors of Monoamine Oxidase-B.”, Cent Nerv Syst Agents Med Chem, vol. 16, no. 2, pp. 105-11, 2016.
Publisher : Cent Nerv Syst Agents Med Chem
Year : 2016
Molecular Docking Studies of Some Novel Antidepressant 5-Substituted Phenyl-3-(Thiophen-2-yl)-4, 5-Dihydro-1h-Pyrazole-1-Carboxamides Against Monoamine Oxidase Isoforms.
Cite this Research Publication : Bijo Mathew, Suresh, J., Anbazhagan, S., and Dev, S., “Molecular Docking Studies of Some Novel Antidepressant 5-Substituted Phenyl-3-(Thiophen-2-yl)-4, 5-Dihydro-1h-Pyrazole-1-Carboxamides Against Monoamine Oxidase Isoforms.”, Cent Nerv Syst Agents Med Chem, vol. 16, no. 2, pp. 75-80, 2016.
Publisher : Cent Nerv Syst Agents Med Chem
Year : 2016
Synthesis, ADME studies, toxicity estimation, and exploration of molecular recognition of thiophene based chalcones towards monoamine oxidase-A and B
Cite this Research Publication : Bijo Mathew, Suresh, J., Mathew, G. Elizabeth, Haridas, A., Suresh, G., and Sabreena, P., “Synthesis, ADME studies, toxicity estimation, and exploration of molecular recognition of thiophene based chalcones towards monoamine oxidase-A and B”, vol. 5, no. 4, pp. 396 - 401, 2016.
Publisher : Volume 5, Issue 4, p.396 - 401 (2016)
Year : 2015
Psychomotor Seizure Screening and in vitro Neuroprotection Assay of Hydrazones Derived from 2-Acetyl Thiophene.
Cite this Research Publication : Bijo Mathew, Mathew, G. E., Suresh, J., Jaseel, M., Usman, D., Subramanyan, P. N. Shiva, Safna, K. F., and Vilapurathu, J. K., “Psychomotor Seizure Screening and in vitro Neuroprotection Assay of Hydrazones Derived from 2-Acetyl Thiophene.”, Cent Nerv Syst Agents Med Chem, 2015.
Publisher : Cent Nerv Syst Agents Med Chem
Year : 2015
Development of Fluorinated Thienylchalcones as Monoamine Oxidase-B Inhibitors: Design, Synthesis, Biological Evaluation and Molecular Docking Studies
Cite this Research Publication : Bijo Mathew, Ucar, G., Yabanogclu-Ciftci, S., Baysal, I., Suresh, J., Mathew, G. Elizabeth, Vilapurathu, J. Kunjumon, Nadeena, A. M., Nabeela, P., Lakshmi, V., and Fathima, A. Haridas an, “Development of Fluorinated Thienylchalcones as Monoamine Oxidase-B Inhibitors: Design, Synthesis, Biological Evaluation and Molecular Docking Studies”, 2015.
Year : 2015
Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies.
Cite this Research Publication : Bijo Mathew, Mathew, G. Elizabeth, Ucar, G., Baysal, I., Suresh, J., Vilapurathu, J. Kunjumon, Prakasan, A., Suresh, J. Kuruppath, and Thomas, A., “Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies.”, Bioorg Chem, vol. 62, pp. 22-9, 2015.
Publisher : Bioorg Chem
Year : 2015
Flavonoids: An Outstanding Structural Core for the Inhibition of Xanthine Oxidase Enzyme
Cite this Research Publication : Bijo Mathew, Suresh, J., Mathew, G. E., Rasheed, S. A., and Jayaraj, J. K. Vilapur, “Flavonoids: An Outstanding Structural Core for the Inhibition of Xanthine Oxidase Enzyme”, 2015.
Year : 2015
Hydrazones as a privileged structural linker in antitubercular agents: a review.
Cite this Research Publication : Bijo Mathew, Suresh, J., Ahsan, M. J., Mathew, G. E., Usman, D., Subramanyan, P. N. S., Safna, K. F., and Maddela, S., “Hydrazones as a privileged structural linker in antitubercular agents: a review.”, Infect Disord Drug Targets, vol. 15, no. 2, pp. 76-88, 2015.
Publisher : Infect Disord Drug Targets
Year : 2015
Determination of in vitro free radical scavenging and antiproliferative effect of Pennisetum alopecuroides on cultured A549 human lung cancer cells.
Cite this Research Publication : G. Elizabeth Mathew, Bijo Mathew, Gokul, S., Krishna, R., and Farisa, M. P., “Determination of in vitro free radical scavenging and antiproliferative effect of Pennisetum alopecuroides on cultured A549 human lung cancer cells.”, Anc Sci Life, vol. 34, no. 3, pp. 175-8, 2015.
Publisher : Anc Sci Life
Year : 2015
Molecular Hybridization and Preclinical Evaluation of Imines From Para-substituted 4-phenyl 2-amino Thiazole Incorporated with Isatin Analogues as Antitubercular Agents
Cite this Research Publication : N. Joy and Bijo Mathew, “Molecular Hybridization and Preclinical Evaluation of Imines From Para-substituted 4-phenyl 2-amino Thiazole Incorporated with Isatin Analogues as Antitubercular Agents”, Anti-Infective Agents, 13 vol., no. 1, 2015.
Publisher : Anti-Infective Agents
Year : 2014
Design, Synthesis, Toxicity Estimation and Molecular Docking Studies of N-(furan-2-yl)-1-(5-substituted) phenyl-1,3,4-oxadiazol-2-yl) methanimine as Antitubercular Agents.
Cite this Research Publication : Bijo Mathew, Suresh, J., Mathew, G. E., Sonia, G., and Krishnan, G. K., “Design, Synthesis, Toxicity Estimation and Molecular Docking Studies of N-(furan-2-yl)-1-(5-substituted) phenyl-1,3,4-oxadiazol-2-yl) methanimine as Antitubercular Agents.”, Indian J Pharm Sci, vol. 76, no. 5, pp. 401-6, 2014.
Publisher : Indian J Pharm Sci
Year : 2014
Synthesis, preclinical evaluation and antidepressant activity of 5-substituted phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides.
Cite this Research Publication : Bijo Mathew, Suresh, J., and Anbazhagan, S., “Synthesis, preclinical evaluation and antidepressant activity of 5-substituted phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides.”, EXCLI J, vol. 13, pp. 437-45, 2014.
Publisher : EXCLI J
Year : 2014
Molecular Recognisation of 3a, 4-Dihydro-3-H-Indeno [1, 2-C] Pyrazole-2- Carboxamide/Carbothioamide Anticonvulsant Analogues Towards GABA-Aminotransferase- An in Silico Approach
Cite this Research Publication : Bijo Mathew and Ahsan, M., “Molecular Recognisation of 3a, 4-Dihydro-3-H-Indeno [1, 2-C] Pyrazole-2- Carboxamide/Carbothioamide Anticonvulsant Analogues Towards GABA-Aminotransferase- An in Silico Approach”, Central Nervous System Agents in Medicinal Chemistry, vol. 14, 2014.
Publisher : Central Nervous System Agents in Medicinal Chemistry
Year : 2014
Synthesis, in silico preclinical evaluation, antidepressant potential of 5-substituted phenyl-3-(thiophen-2-yl)-4,5-dihydro-1h-pyrazole-1-carboxamides
Cite this Research Publication : Bijo Mathew, Suresh, J., and Anbazhagan, S., “Synthesis, in silico preclinical evaluation, antidepressant potential of 5-substituted phenyl-3-(thiophen-2-yl)-4,5-dihydro-1h-pyrazole-1-carboxamides”, Biomedicine & Aging Pathology, vol. 4, pp. 327-333, 2014.
Publisher : Biomedicine & Aging Pathology
Year : 2014
Proposed interaction of some novel antidepressant pyrazolines against monoamine oxidase isoforms. Molecular docking studies and PASS assisted in silico approach
Cite this Research Publication : Bijo Mathew, Suresh, J., Anbazhagan, S., and Dev, S., “Proposed interaction of some novel antidepressant pyrazolines against monoamine oxidase isoforms. Molecular docking studies and PASS assisted in silico approach”, Biomedicine & Aging Pathology, vol. 4, pp. 297-301, 2014.
Publisher : Biomedicine & Aging Pathology
Year : 2014
Isolation of a bioactive flavonoid from Spilanthes calva D.C. in vitro xanthine oxidase assay and in silico study
Cite this Research Publication : P. Jayaraj, Bijo Mathew, Parimaladevi, B., V. Ramani, A., and Govindarajan, R., “Isolation of a bioactive flavonoid from Spilanthes calva D.C. in vitro xanthine oxidase assay and in silico study”, Biomedicine & Preventive Nutrition, vol. 4, pp. 481-484, 2014.
Publisher : Biomedicine & Preventive Nutrition
Year : 2014
Isolation of chemical constituents from Spilanthes calva DC: Toxicity, anthelmintic efficacy and in silico studies
Cite this Research Publication : P. Jayaraj, Bijo Mathew, Mani, C., and Govindarajan, R., “Isolation of chemical constituents from Spilanthes calva DC: Toxicity, anthelmintic efficacy and in silico studies”, Biomedicine & Preventive Nutrition, vol. 4, pp. 417-423, 2014.
Publisher : Biomedicine & Preventive Nutrition
Year : 2014
Heteroaryl chalcones: Mini review about their therapeutic voyage
Cite this Research Publication : Bijo Mathew, Suresh, J., Anbazghagan, S., Paulraj, J., and Krishnan, G. K., “Heteroaryl chalcones: Mini review about their therapeutic voyage”, Biomedicine & Preventive Nutrition, vol. 4, pp. 451-458, 2014.
Publisher : Biomedicine & Preventive Nutrition
Year : 2014
Isolation and molecular recognization of 6-prenyl apigenin towards MAO-A as the active principle of seeds of Achyranthes aspera
Cite this Research Publication : S. Janet Beula, V. Raj, B. Anada, and Bijo Mathew, “Isolation and molecular recognization of 6-prenyl apigenin towards MAO-A as the active principle of seeds of Achyranthes aspera”, Biomedicine & Preventive Nutrition, vol. 4, pp. 379-382, 2014.
Publisher : Biomedicine & Preventive Nutrition
Year : 2014
Plant secondary metabolites- potent inhibitors of monoamine oxidase isoforms.
Cite this Research Publication : Bijo Mathew, Suresh, J., Mathew, G. E., Parasuraman, R., and Abdulla, N., “Plant secondary metabolites- potent inhibitors of monoamine oxidase isoforms.”, Cent Nerv Syst Agents Med Chem, vol. 14, no. 1, pp. 28-33, 2014.
Publisher : Cent Nerv Syst Agents Med Chem
Year : 2013
Design of 1-(furan-2-yl)-N-(5-substituted phenyl-1, 3, 4-thiadiazol-2-yl) methanimine derivatives as Enoyl-ACP reductase inhibitors: Synthesis, molecular docking studies and anti-tubercular activity
Cite this Research Publication : Bijo Mathew, Mathew, G., Sonia, G., Kumar, A., Charles, N., and Kumar, P., “Design of 1-(furan-2-yl)-N-(5-substituted phenyl-1, 3, 4-thiadiazol-2-yl) methanimine derivatives as Enoyl-ACP reductase inhibitors: Synthesis, molecular docking studies and anti-tubercular activity”, Bangladesh Journal of Pharmacology, vol. 8, 2013.
Publisher : Bangladesh Journal of Pharmacology
Year : 2013
Antitumour activity of 5-[(2E)-1-(1H-benzimidazol-2-yl)-3-substituted phenylprop-2-en-1-ylidene] pyrimidine-2,4,6(1H,3H,5H)-triones against Dalton’s ascitic lymphoma in mice
Cite this Research Publication : Bijo Mathew, Suresh, J., and Vinod, D., “Antitumour activity of 5-[(2E)-1-(1H-benzimidazol-2-yl)-3-substituted phenylprop-2-en-1-ylidene] pyrimidine-2,4,6(1H,3H,5H)-triones against Dalton’s ascitic lymphoma in mice”, Medicinal Chemistry Research, vol. 22, no. 8, pp. 3911 - 3917, 2013.
Publisher : Medicinal Chemistry Research
Year : 2013
Synthesis and in silico design of some novel imines of 5- amino-1,3,4-thiadiazole-2-thiol linked to (1h-benzimidazole-2-yl) 3-substituted phenyl prop-2-enes
Cite this Research Publication : Bijo Mathew, Suresh, J., and Anbazhagan, S., “Synthesis and in silico design of some novel imines of 5- amino-1,3,4-thiadiazole-2-thiol linked to (1h-benzimidazole-2-yl) 3-substituted phenyl prop-2-enes”, Indian. J. Heterocycl. Chem, vol. 22, pp. 337-340, 2013.
Publisher : Indian. J. Heterocycl. Chem
Year : 2013
Hypnotic profile of imines from benzimidazole chalcones: mechanism of synthesis, DFT studies and in silico screening.
Cite this Research Publication : Bijo Mathew, Suresh, J., Anbazhagan, S., and Devaraji, V., “Hypnotic profile of imines from benzimidazole chalcones: mechanism of synthesis, DFT studies and in silico screening.”, Cent Nerv Syst Agents Med Chem, vol. 13, no. 3, pp. 207-16, 2013.
Publisher : Cent Nerv Syst Agents Med Chem
Year : 2013
Pyrazoline: a promising scaffold for the inhibition of monoamine oxidase.
Cite this Research Publication : Bijo Mathew, Suresh, J., Anbazhagan, S., and Mathew, G. Elizabeth, “Pyrazoline: a promising scaffold for the inhibition of monoamine oxidase.”, Cent Nerv Syst Agents Med Chem, vol. 13, no. 3, pp. 195-206, 2013.
Publisher : Cent Nerv Syst Agents Med Chem
Year : 2013
Synthesis and PASS-assisted in silico approach of some novel 2-substituted benzimidazole bearing a pyrimidine-2, 4, 6(trione) system as mucomembranous protector.
Cite this Research Publication : Bijo Mathew, Suresh, J., and Anbazhagan, S., “Synthesis and PASS-assisted in silico approach of some novel 2-substituted benzimidazole bearing a pyrimidine-2, 4, 6(trione) system as mucomembranous protector.”, J Pharm Bioallied Sci, vol. 5, no. 1, pp. 39-43, 2013.
Publisher : J Pharm Bioallied Sci
Year : 2012
Microwave Assisted Synthesis, Physico-chemical Properties and Antioxidant Activity of alpha,beta-Unsaturated Benzimidazole Derivatives Incorporated with Baritone Moiety
Cite this Research Publication : Bijo Mathew, Suresh, J., and Anbazhagan, S., “Microwave Assisted Synthesis, Physico-chemical Properties and Antioxidant Activity of alpha,beta-Unsaturated Benzimidazole Derivatives Incorporated with Baritone Moiety”, ASIAN JOURNAL OF CHEMISTRY, vol. 25, pp. 1853-1856, 2012.
Publisher : ASIAN JOURNAL OF CHEMISTRY
Year : 2012
Isolation, in silico design and anti-inflammatory activity of spirosolenol from the roots of Solanum anguvi
Cite this Research Publication : Bijo Mathew, Mathew, G. E., George, S., Shamnas, M., and Raj, V. B. A., “Isolation, in silico design and anti-inflammatory activity of spirosolenol from the roots of Solanum anguvi”, Chemical Sciences Journal, 2012.
Publisher : Chemical Sciences Journal
Year : 2012
A Green route approach of α, β unsaturated ketone having a benzimidazole tail and their virtual screening on the molecular descriptors for predicting the CNS-drug likeness
Cite this Research Publication : Bijo Mathew, Mathew, G. Elizebeth, ,, C., M. Musthafa, and P., F., “A Green route approach of α, β unsaturated ketone having a benzimidazole tail and their virtual screening on the molecular descriptors for predicting the CNS-drug likeness”, Asian J. Research Chem., vol. 5, no. 1, pp. 65-68, 2012.
Publisher : Asian J. Research Chem
Year : 2011
Synthesis of some thiazolidinone derivatives from indole-2 carboxylic acid and evaluation of its xanthine oxidase inhibitory and antioxidant activity
Cite this Research Publication : B. C, B., M., A., M., and M., S., “Synthesis of some thiazolidinone derivatives from indole-2 carboxylic acid and evaluation of its xanthine oxidase inhibitory and antioxidant activity”, International Journal of ChemTech Research, vol. 3, no. 2, pp. 671-675, 2011.
Publisher : International Journal of ChemTech Research
Year : 2011
Diuretic activity of leaves of garcinia cambogia in rats.
Cite this Research Publication : G. E. Mathew, Bijo Mathew, Shaneeb, M. M., and Nyanthara, B., “Diuretic activity of leaves of garcinia cambogia in rats.”, Indian J Pharm Sci, vol. 73, no. 2, pp. 228-30, 2011.
Publisher : Indian J Pharm Sci
Year : 2011
Phytochemical evaluation and lipid lowering property of leaves of Vitex negun- do linn. in hyper cholestremic rats
Cite this Research Publication : E. Githa, Mathew,, and Bijo Mathew, “Phytochemical evaluation and lipid lowering property of leaves of Vitex negun- do linn. in hyper cholestremic rats”, IJPSRR, vol. 2, 2011.
Publisher : IJPSRR
Year : 2011
Anthelmintic activity of leaves of garcinia cambogia
Cite this Research Publication : G. E. Mathew, Bijo Mathew, Sheneeb, M., Nyanthara, N., and Haribabu, Y., “Anthelmintic activity of leaves of garcinia cambogia”, International Journal of Research in Pharmaceutical Sciences, vol. 2, pp. 63-65, 2011.
Publisher : International Journal of Research in Pharmaceutical Sciences
Year : 2011
Synthesis, characterization and antimicrobial screening of some 2-amino, 5(phenyl substituted) 1, 3, 4-thiadiazole derivatives
Cite this Research Publication : Bijo Mathew, AJ, J., GE, M., S, S., and SS, K., “Synthesis, characterization and antimicrobial screening of some 2-amino, 5(phenyl substituted) 1, 3, 4-thiadiazole derivatives”, International Journal of ChemTech Research, vol. 1, no. 3, pp. 364-368, 2011.
Publisher : International Journal of ChemTech Research
Year : 2010
Synthesis, molecular properties and anthelmintic activity of some schiff bases of 1, 3, 4 thiadiazole derivatives
Cite this Research Publication : B. Mathew, Vakketh, S. S., and Kumar, S. S., “Synthesis, molecular properties and anthelmintic activity of some schiff bases of 1, 3, 4 thiadiazole derivatives”, Der pharma chemica, vol. 2, pp. 337-343, 2010.
Publisher : Der pharma chemica
Year : 2010
Phytochemical evaluation and anticancer screening of rhizomes of Kaempferia galanga
Cite this Research Publication : Bijo Mathew, M, V., GE, M., and KM, T., “Phytochemical evaluation and anticancer screening of rhizomes of Kaempferia galanga”, InternationalResearch Journal of Pharmaceutical Sciences, vol. 1, no. 1, pp. 11-15, 2010.
Publisher : InternationalResearch Journal of Pharmaceutical Sciences
Year : 2010
Synthesis, Characterisation of some 2-azetidinone derivatives from 2-aminopyridine and evaluation of their antimicrobial activity
Cite this Research Publication : Bijo Mathew, Mathew, G. Elizebeth, Mathew, N., and Vijayabaskaran, M., “Synthesis, Characterisation of some 2-azetidinone derivatives from 2-aminopyridine and evaluation of their antimicrobial activity”, Der Pharma Chemica, vol. 2, no. 6, pp. 238-242, 2010.
Publisher : Der Pharma Chemica