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Dr. Bijo Mathew

Associate Professor

Dr. Bijo Mathew is an Associate Professor at the Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Kochi, India.

Bio

Dr. Bijo Mathew is Associate Professor of Pharmaceutical Chemistry at the Amrita School of Pharmacy, Kochi, India. Dr. Bijo Mathew obtained his M.Pharm in Pharmaceutical Chemistry from The Tamilnadu Dr. M.G.R. Medical University, Tamilnadu, India in 2008 and Ph.D. in Pharmaceutical Sciences from Jawaharlal Nehru Technological University, Hyderabad, India in 2016. Mathew’s primary areas of focus are in drug discovery of neurodegenerative disorders, cancer and molecular modelling. His main research interest is on the design of enzyme inhibitors, and especially MAOs, ChEs and BACE1. He has published 157 papers, [h-index = 31; the number of citations: 2517 in Google scholar; h-index = 31; the number of citations: 2128 in Scopus [August 2021]. With 13 years of teaching and research experience, Mathew authored 1 book, 1 edited book, 5 book chapters and 26 invited talk in national and international level. Dr. B. Mathew is serving as a chief executive guest editor of the journals of Molecules, Current Topics in Medicinal Chemistry, and Current Drug Targets. He is serving in the editorial board of Combinatorial Chemistry and High Throughput Screening. He received Amrita Vishwa Vidyapeetham Chancellor’s Publication Award in 2021. He received one patent from Korean Intellectual Property of Office in the topic of protective or therapeutic compositions of neurological disorders containing furano chalcones as effective agents.

Education

  • 2010-2016: Ph. D. (Pharmaceutical Science)
    Jawaharlal Nehru Technological University, Hyderabad, India.
    Title: Synthesis, Characterisation, and Pharmacological Evaluation of Some Heterocyclic Derivatives under the supervision of Dr. A. Jerad Suresh (Professor & Principal, Department of Pharmaceutical Chemistry, College of Pharmacy, Madras Medical College, Chennai, India.)
  • 2006-2008: M. Pharm. (Pharmaceutical Chemistry)
    The Tamilnadu Dr. M. G. R. Medical University, Chennai, India.
  • 2001-2005: B. Pharm.
    The Tamilnadu Dr. M. G. R. Medical University, Chennai, India.
  • 1999-2001: Pre-degree
    Mahatma Gandhi University, Kottayam, India.

Area of Interest

  • Chemistry and biological exploration of various class of chalcones.
  • Synthesis of and pharmacological exploration of heterocyclic nucleus such as benzimidazole, thiadiazole, pyrimidine, furan, pyrazoline and thiazole etc.
  • CNS depressant, anticonvulsant, anticancer, antioxidant,antitubercular activity.
  • Design of MAO, Acetylcholinesterase and Hsp90 inhibitors.
  • Microwave assisted synthesis.
  • Structural elucidation of organic molecules by IR, NMR and MASS (mass fragmentation pattern) technique.
  • Molecular docking, Dynamics, Pharmacophore mapping, 3D-QSAR studies.
  • Isolation of natural secondary metabolites from medicinal plant and their insilico studies.

Expert in Drug Design Softwares

  • AutoDock4.2, Molegrow, Arguslab, Hex, LigandScout, Open-Babel, Accelery Discovery, Chem-3D.

Section Editor

  • Coronaviruses [BenthamScience]

Editorial Member

  • Combinatorial Chemistry & High Throughput Screening [BenthamScience]

Chief Executive Guest Editor

  1. Molecules [MDPI] [Impact Factor®:4.4].
    Title of the thematic issue: Recent drug design strategy of the design of molecules against Alzheimer’s disease and Parkinson’s diseases . [Issue under Preparation].
  2. Current Topics in Medicinal Chemistry [Bentham Science] [Impact Factor®:3.3].
    Title of the thematic issue: SAR analysis of various heterocyclic compounds in medicinal chemistry: Recent Updates. [Issue under Preparation].
  3. Current Drug Targets [BenthamScience] [Impact Factor®:2.64].
    Title of the Thematic Issue: Mitochondrial dysfunction and traffic jams in neurodegenerative disorders. [BenthamScience] [Issue under Preparation].
  4. Combinatorial Chemistry & High Throughput Screening [BenthamScience] [Impact Factor®:1.56].
    Title of the Thematic Issue: Inhibitors of Monoamine Oxidase and Acetylcholinesterase as a front runner in CNS drug discovery [Issue under preparation-2020].
  5. Combinatorial Chemistry & High Throughput Screening [BenthamScience] [Impact Factor®:1.56].
    Title of the Thematic Issue: Computational chemistry andsynthetic strategy of the design of novel Monoamine oxidase inhibitors. [2017, 20, 459-578]
  6. Central Nervous System Agents in Medicinal Chemistry [BenthamScience]
    Title of the Thematic Issue: Rational approaches for the design of Monoamine Oxidase Inhibitors [2016, volume 16, Issue 2- Page no: 73-164]

Projects under Supervision

  • B. Pharm. level – 11
  • M. Pharm. level – 1
  • Ph. D.- 4 (ongoing)
Publications

Journal Article

Year : 2021

Replacement of chalcone-ethers with chalcone-thioethers as potent and highly selective monoamine oxidase-b inhibitors and their protein-ligand interactions

Authors : Dr. Bijo Mathew, Jong Min Oh, Ahmed Khames, Mohamed A Abdelgawad, T M Rangarajan, Lekshmi R Nath, Clement Agoni, Mahmoud E S Soliman, Githa Elizabeth Mathew, Hoon Kim

Publisher : Pharmaceuticals

Mathew, B., Oh, J.M., Khames, A., Mathew, G.E., Kim, H. Replacement of chalcone-ethers with chalcone-thioethers as potent and highly selective monoamine oxidase-b inhibitors and their protein-ligand interactions, Pharmaceuticals, 2021, 14(11),1148, DOI: 10.3390/ph14111148

Year : 2021

SAR Analysis of Various Heterocyclic Compounds in Medicinal Chemistry: Recent Updates-Part-I

Authors : Dr. Bijo Mathew

Publisher : Current Topics in Medicinal Chemistry

Mathew, B., SAR Analysis of Various Heterocyclic Compounds in Medicinal Chemistry: Recent Updates-Part-I, Current Topics in Medicinal Chemistry, 2021, 21(30), pp. 2694, doi: 10.2174/156802662130211210151841.

Year : 2021

Synthesis of new 1-aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone oxime ether derivatives and investigation of their cytotoxic effects

Authors : Dr. Bijo Mathew, Mehmet Abdullah Alagöz, Arzu Karakurt, Ceylan Hepokur, Emine Şalva, Tijen Önkol, Mohammed M. Ghoneim, Mohamed A. Abdelgawad, Ahmed Khames, Hoon Kim

Publisher : Processes

Alagöz, M.A., Karakurt, A., Hepokur, C, Kim, H., Mathew, B. Synthesis of new 1-aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone oxime ether derivatives and investigation of their cytotoxic effects, Processes, 2021, 9(11), 2019; https://doi.org/10.3390/pr9112019

Year : 2021

Selected Class of Enamides Bearing Nitro Functionality as Dual-Acting with Highly Selective Monoamine Oxidase-B and BACE1 Inhibitors

Authors : Dr. Bijo Mathew, Anusree Venkidath, Jong Min Oh, Sanal Dev, Elham Amin, Shebina P. Rasheed, Ajeesh Vengamthodi, Nicola Gambacorta, Ahmed Khames, Mohamed A. Abdelgawad, Ginson George, Orazio Nicolotti, Hoon Kim

Publisher : Molecules

Venkidath, A., Oh, J.M., Dev, S., (...), Kim, H., Mathew, B. Selected class of enamides bearing nitro functionality as dual-acting with highly selective monoamine oxidase-b and bace1 inhibitors, Molecules, Volume 26, Issue 19, 10.3390/molecules26196004

Year : 2021

An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.

Authors : Dr. Bijo Mathew, Harilal, Seetha; Musa, Arafa; Kumar, Rajesh; Parambi, Della Grace Thomas; Jose, Jobin; Uddin, Md Sahab; Shah, Muhammad Ajmal; Behl, Tapan; Unnikrishnan, Mazhuvancherry Kesavan

Publisher : Current Drug Targets

Bijo Mathew, Harilal, S., Musa, A., Kumar, R., Parambi, D. Grace Thom, Jose, J., Uddin, M. Sahab, Shah, M. Ajmal, Behl, T., and Unnikrishnan, M. Kesavan, “An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.”, Current Drug Targets, vol. 22, no. 7, pp. 823 - 834, 2021.

Year : 2021

A Comprehensive Overview of Colon Cancer- A Grim Reaper of the 21st Century

Authors : Dr. Bijo Mathew, Kumar, Rajesh; Harilal, Seetha; Carradori, Simone

Publisher : Current Medicinal Chemistry

R. Kumar, Harilal, S., Carradori, S., and Bijo Mathew, “A Comprehensive Overview of Colon Cancer- A Grim Reaper of the 21st Century”, Current Medicinal Chemistry, Volume 28, (14), pp. 2657-2696, (2021)

Year : 2021

Revealing the role of fluorine pharmacophore in chalcone scaffold for shifting the MAO-B selectivity: investigation of a detailed molecular dynamics and quantum chemical study.

Authors : Dr. Bijo Mathew, Olotu, Fisayo A; Joy, Monu; Abdelgawad, Mohamed A; Narayanan, Siju E; Soliman, Mahmoud E; Bijo Mathew

Publisher : Journal of Biomolecular Structure and Dynamics

F. A. Olotu, Joy, M., Abdelgawad, M. A., Narayanan, S. E., Soliman, M. E., and Bijo Mathew, “Revealing the role of fluorine pharmacophore in chalcone scaffold for shifting the MAO-B selectivity: investigation of a detailed molecular dynamics and quantum chemical study.”, Journal of Biomolecular Structure and Dynamics 2021, 39(16), pp. 6126-6139

Year : 2021

Development of methylthiosemicarbazones as new reversible monoamine oxidase-B inhibitors for the treatment of Parkinson’s disease.

Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Oh, Jong Min; Mohan, Kumar; Tengli, Anandkumar; Bijo Mathew; Kim, Hoon

Publisher : Journal of Biomolecular Structure and Dynamics

G. Elizabeth Mathew, Oh, J. Min, Mohan, K., Tengli, A., Bijo Mathew, and Kim, H., “Development of methylthiosemicarbazones as new reversible monoamine oxidase-B inhibitors for the treatment of Parkinson's disease.”, Journal of Biomolecular Structure and Dynamics, 2021, 39(13), pp. 4786-4794.

Year : 2021

Navigating into the chemical space of monoamine oxidase inhibitors by artificial intelligence and chemoinformatics approach

Authors : Dr. Bijo Mathew, Kumar S, Nair AS, Bhaskar V, Sudevan TS, Vishal PK, Khames A, Abdelgawad MA

Publisher : ACS OMEGA

Kumar S, Nair AS, Bhaskar V, Sudevan TS, Vishal PK, Khames A, Abdelgawad MA, and Bijo Mathew, “Navigating into the chemical space of monoamine oxidase inhibitors by artificial intelligence and chemoinformatics approach”, ACS OMEGA [Accepted], 2021.

Year : 2021

An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.

Authors : Dr. Bijo Mathew, Harilal, Seetha; Musa, Arafa; Kumar, Rajesh; Parambi, Della Grace Thomas; Jose, Jobin; Uddin, Md Sahab; Shah, Muhammad Ajmal; Behl, Tapan; Unnikrishnan, Mazhuvancherry Kesavan

Publisher : Current Drug Targets

Bijo Mathew, Harilal, S., Musa, A., Kumar, R., Parambi, D. Grace Thom, Jose, J., Uddin, M. Sahab, Shah, M. Ajmal, Behl, T., and Unnikrishnan, M. Kesavan, “An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.”, Current Drug Targets, vol. 22, no. 7, pp. 823 - 834, 2021.

Year : 2021

Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations.

Authors : Dr. Bijo Mathew, Sasidharan, Rani; Eom, Bo Hyun; Heo, Jeong Hyun; Park, Jong Eun; Abdelgawad, Mohamed A; Musa, Arafa; Gambacorta, Nicola; Nicolotti, Orazio; Manju, Sreedharannair Leelabaiamma; Kim, Hoon

Publisher : Journal of Enzyme Inhibition and Medicinal Chemistry

R. Sasidharan, Eom, B. Hyun, Heo, J. Hyun, Park, J. Eun, Abdelgawad, M. A., Musa, A., Gambacorta, N., Nicolotti, O., Manju, S. Leelabaiam, Bijo Mathew, and Kim, H., “Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations.”, Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 36, no. 1, pp. 188-197, 2021.

Year : 2021

Recent updates on pyrazolines derivatives as promising candidates for neuropsychiartic and neurodegenerative disorders

Authors : Dr. Bijo Mathew, Rangarajan TM

Publisher : Current Topics in Medicinal Chemistry

Rangarajan TM and Bijo Mathew, “Recent updates on pyrazolines derivatives as promising candidates for neuropsychiartic and neurodegenerative disorders”, Current Topics in Medicinal Chemistry, 2021;21(30):2695-2714, DOI: 10.2174/1568026621999210902123132

Year : 2021

COVID-19 and domestic animals: Exploring the species barrier crossing, zoonotic and reverse zoonotic transmission of SARS-CoV-2.

Authors : Dr. Bijo Mathew, Kumar, Rajesh; Harilal, Seetha; Al-Sehemi, Abdullah G; Paninipara, Mehboobali; Behl, Tapan; Mathew, Githa Elizabeth

Publisher : Curr Pharm Des

R. Kumar, Harilal, S., Al-Sehemi, A. G., Paninipara, M., Behl, T., Mathew, G. Elizabeth, and Bijo Mathew, “COVID-19 and domestic animals: Exploring the species barrier crossing, zoonotic and reverse zoonotic transmission of SARS-CoV-2.”, Current Pharmaceutical Design, Volume 27, Issue 9, pp. 1194-1201, (2021)

Year : 2021

Ameliorative effect of ethoxylated chalcone based MAO-B inhibitor on behavioural predictors of Haloperidol-induced Parkinsonism in mice: Evidence of its anti-oxidative role against Parkinson’s diseases

Authors : Dr. Bijo Mathew, Maliyakkal N, Saleem U, Anwar F, Shah FA, Ahmad B, Umer F, Almoyad MAA, DGT, P., Beeran AP, Nath LR, Aleya L

Publisher : Environmental Science and Pollution Research

Maliyakkal N, Saleem U, Anwar F, Shah FA, Ahmad B, Umer F, Almoyad MAA, DGT, P., Beeran AP, Nath LR, Aleya L, and Bijo Mathew, “Ameliorative effect of ethoxylated chalcone based MAO-B inhibitor on behavioural predictors of Haloperidol-induced Parkinsonism in mice: Evidence of its anti-oxidative role against Parkinson’s diseases”, Environmental Science and Pollution Research. [Accepted], 2021.

Year : 2021

Dysregulation of the Gut-Brain Axis, Dysbiosis and Influence of Numerous Factors on Gut Microbiota Associated Parkinson’s Disease

Authors : Dr. Bijo Mathew, Kaur, Gagandeep; Behl, Tapan; Bungau, Simona; Kumar, Arun; Uddin, Md Sahab; Mehta, Vineet; Zengin, Gokhan; Bijo Mathew; Shah, Muhammad Ajmal; Arora, Sandeep

Publisher : Curr Neuropharmacol

G. Kaur, Behl, T., Bungau, S., Kumar, A., Uddin, M. Sahab, Mehta, V., Zengin, G., Bijo Mathew, Shah, M. Ajmal, and Arora, S., “Dysregulation of the Gut-Brain Axis, Dysbiosis and Influence of Numerous Factors on Gut Microbiota Associated Parkinson's Disease.”, Curr Neuropharmacol, vol. 19, no. 2, pp. 233-247, 2021.

Year : 2021

The Chronicle of COVID-19 and Possible Strategies to Curb the Pandemic

Authors : Dr. Bijo Mathew, Kumar, Rajesh; Harilal, Seetha; Al-Sehemi, Abdullah G; Mathew, Githa Elizabeth; Carradori, Simone

Publisher : Curr Med Chem,

R. Kumar, Harilal, S., Al-Sehemi, A. G., Mathew, G. Elizabeth, Carradori, S., and Bijo Mathew, “The Chronicle of COVID-19 and Possible Strategies to Curb the Pandemic”, Current Medicinal Chemistry, 2021, 28(15), pp. 2852-2886

Year : 2021

Insights into an Immunotherapeutic Approach to Combat Multidrug Resistance in Hepatocellular Carcinoma

Authors : Dr. Bijo Mathew, Devan AR; Kumar AR; Nair B; Anto NP; Muraleedharan A; Bijo Mathew; Kim H; Nath LR

Publisher : Pharmaceuticals

Devan AR, Kumar AR, Nair B, Anto NP, Muraleedharan A, Bijo Mathew, Kim H, and Nath LR, “Insights into an Immunotherapeutic Approach to Combat Multidrug Resistance in Hepatocellular Carcinoma”, Pharmaceuticals, vol. 14, no. 7, p. 656, 2021.

Year : 2021

New Aspects of Monoamine Oxidase B Inhibitors: The Key Role of Halogens to Open the Golden Door.

Authors : Dr. Bijo Mathew, Carradori, Simone; Guglielmi, Paolo; Uddin, Md Sahab; Kim, Hoon

Publisher : Current Medicinal Chemistry

Bijo Mathew, Carradori, S., Guglielmi, P., Uddin, M. Sahab, and Kim, H., “New Aspects of Monoamine Oxidase B Inhibitors: The Key Role of Halogens to Open the Golden Door.”, Current Medicinal Chemistry, 2021, 28(2), pp. 266-283

Year : 2021

Current Progress in Quinazoline Derivatives as Acetylcholinesterase and Monoamine Oxidase Inhibitors

Authors : Dr. Bijo Mathew, Rehuman, Nisha Abdul; Al-Sehemi, Abdullah G.; Parambi, Della Grace Thomas; Rangarajan, T. M.; Nicolotti, Orazio; Kim, Hoon

Publisher : ChemistrySelect

N. Abdul Rehuman, Al-Sehemi, A. G., Parambi, D. Grace Thom, Rangarajan, T. M., Nicolotti, O., Kim, H., and Bijo Mathew, “Current Progress in Quinazoline Derivatives as Acetylcholinesterase and Monoamine Oxidase Inhibitors”, ChemistrySelect, vol. 6, no. 28, pp. 7162-7182, 2021. DOI: https://doi.org/10.1002/slct.202101077

Year : 2021

Deciphering the detailed structure – activity relationship of coumarins as Monoamine oxidase enzyme inhibitors – An updated review.

Authors : Dr. Bijo Mathew, Vishal Payyalot Koyiparambath; Krishnendu Pr; M RangarajanT; A. Al-Sehemi; M. Pannipara; Vaishnav Bhaskar; Aathira Sujathan Nair; Sachithra Thazhathuveedu Sudevan; Sunil Kumar

Publisher : Wiley-VCH

V. Payyalot Koyiparambath, Pr, K., RangarajanT, M., Al-Sehemi, A., Pannipara, M., Bhaskar, V., Nair, A. Sujathan, Sudevan, S. Thazhathuv, Kumar, S., and Bijo Mathew, “Deciphering the detailed structure-activity relationship of coumarins as Monoamine oxidase enzyme inhibitors-An updated review.”, Chemical Biology and Drug Design, Wiley-VCH (2021), 98(4), pp. 655-673

Year : 2021

Synthesis of N ′-(4-/3-/2-/Non-substituted benzylidene)-4-[(4-methylphenyl)sulfonyloxy] Benzohydrazides and Evaluation of Their Inhibitory Activities against Monoamine Oxidases and β-Secretase.

Authors : Dr. Bijo Mathew, H. Erdinç Sellitepe, Oh, J. Min, Doğan, İ. Selin, Yildirim, S., Aksel, A. Buğra, Jeong, G. Seok, Khames, A., Abdelgawad, M. A., Gambacorta, N., Nicolotti, O., Bijo Mathew, and Kim, H.

Publisher : Applied Sciences

H. Erdinç Sellitepe, Oh, J. Min, Doğan, İ. Selin, Yildirim, S., Aksel, A. Buğra, Jeong, G. Seok, Khames, A., Abdelgawad, M. A., Gambacorta, N., Nicolotti, O., Bijo Mathew, and Kim, H., “Synthesis of N ′-(4-/3-/2-/Non-substituted benzylidene)-4-[(4-methylphenyl)sulfonyloxy] Benzohydrazides and Evaluation of Their Inhibitory Activities against Monoamine Oxidases and β-Secretase.”, Applied Sciences (2076-3417) , vol. 11, no. 13, pp. 5830-5830, 2021.

Year : 2021

Current perspective of COVID-19 on neurology: A mechanistic insight.

Authors : Dr. Bijo Mathew, Kumar, Rajesh; Harilal, Seetha; Pappachan, Leena K;

Publisher : Bentham Science

R. Kumar, Harilal, S., Pappachan, L. K., and Bijo Mathew, “Current perspective of COVID-19 on neurology: A mechanistic insight.”, Combinatorial Chemistry and High Throughput Screening (Accepted), 2021.

Year : 2021

Development of 2D, 3D-QSAR and pharmacophore modeling of chalcones for the inhibition of monoamine oxidase B.

Authors : Dr. Bijo Mathew, Acevedo, C. H., Sc, D., Rangarajan TM, MS, K., NP, N. Punnoth Po, L, S., and MT., S

Publisher : Combinatorial Chemistry and High Throughput Screening

Bijo Mathew, Acevedo, C. H., Sc, D., Rangarajan TM, MS, K., NP, N. Punnoth Po, L, S., and MT., S., “Development of 2D, 3D-QSAR and pharmacophore modeling of chalcones for the inhibition of monoamine oxidase B. ”, Combinatorial Chemistry and High Throughput Screening. (Accepted), 2021.

Year : 2021

Trimethoxylated Halogenated Chalcones as Dual Inhibitors of MAO-B and BACE-1 for the Treatment of Neurodegenerative Disorders.

Authors : Dr. Bijo Mathew, Dr Lekshmi.R.Nath, Vishal, Payyalot Koyiparambath; Oh, Jong Min; Khames, Ahmed; Abdelgawad, Mohamed A; Nair, Aathira Sujathan; Gambacorta, Nicola; Ciriaco, Fulvio; Nicolotti, Orazio; Kim, Hoon

Publisher : Pharmaceutics

P. Koyiparamb Vishal, Oh, J. Min, Khames, A., Abdelgawad, M. A., Nair, A. Sujathan, Nath, L. R., Gambacorta, N., Ciriaco, F., Nicolotti, O., Kim, H., and Bijo Mathew, “Trimethoxylated Halogenated Chalcones as Dual Inhibitors of MAO-B and BACE-1 for the Treatment of Neurodegenerative Disorders.”, Pharmaceutics, vol. 13, no. 6, 2021.

Year : 2021

Targeting cellular batteries for the therapy of neurological diseases

Authors : Dr. Bijo Mathew, Arpita Arora, Tapan Behl, Aayush Sehgal, Sukhbir Singh, Neelam Sharma & Simona Bungau

Publisher : Springer Nature

A. Arora, Behl, T., Sehgal, A., Singh, S., Sharma, N., Bijo Mathew, and Bungau, S., “Targeting cellular batteries for the therapy of neurological diseases”, vol. 28, no. 31, pp. 41517 - 41532, 2021.

Year : 2021

Trimethoxy Crown Chalcones as Multifunctional Class of Monoamine Oxidase Enzyme Inhibitors.

Authors : Dr. Bijo Mathew, Maliyakkal, Naseer; Baysal, Ipek; Tengli, Anandkumar; Ucar, Gülberk; Almoyad, Mohammad Ali Abdullah; Parambi, Della Grace Thomas; Gambacorta, Nicola; Nicolotti, Orazio; Beeran, Asmy Appadath

Publisher : Bentham Science

N. Maliyakkal, Baysal, I., Tengli, A., Ucar, G., Almoyad, M. Ali Abdull, Parambi, D. Grace Thom, Gambacorta, N., Nicolotti, O., Beeran, A. Appadath, and Bijo Mathew, “Trimethoxy Crown Chalcones as Multifunctional Class of Monoamine Oxidase Enzyme Inhibitors.”, Combinatorial Chemistry and High Throughput Screening, 2021.

Year : 2021

An Update of Synthetic Approaches and Structure-Activity Relationships of Various Classes of Human MAO-B Inhibitors

Authors : Dr. Bijo Mathew, Pratibha Sharma; Dr. Manjinder Singh;

Publisher : ChemistrySelect

P. Sharma, Singh, D. Manjinder, and Bijo Mathew, “An Update of Synthetic Approaches and Structure-Activity Relationships of Various Classes of Human MAO-B Inhibitors”, ChemistrySelect, vol. 6, no. 7, pp. 1404-1429, 2021.

Year : 2021

Synthesis, Cytotoxicity and Anti-Proliferative Activity Against AGS Cells of New 3(2)-Pyridazinone Derivatives Endowed with a Piperazinyl Linker.

Authors : Dr. Bijo Mathew, Alagöz, Mehmet Abdullah; Özdemir, Zeynep; Uysal, Mehtap; Carradori, Simone; Gallorini, Marialucia; Ricci, Alessia; Zara, Susi

Publisher : Basel

M. Abdullah Alagöz, Özdemir, Z., Uysal, M., Carradori, S., Gallorini, M., Ricci, A., Zara, S., and Bijo Mathew, “Synthesis, Cytotoxicity and Anti-Proliferative Activity Against AGS Cells of New 3(2)-Pyridazinone Derivatives Endowed with a Piperazinyl Linker.”, Pharmaceuticals (Basel), Volume 14, Issue 3, 183, pp. 1-27 (2021)

Year : 2021

Neuroprotective Effects of Ellagic Acid in Alzheimer’s Disease: Focus on Underlying Molecular Mechanisms of Therapeutic Potential.

Authors : Dr. Bijo Mathew, Nimra Javaid, Muhammad A. Shah, Azhar Rasul, Zunera Chauhdary, Uzma Saleem, Haroon Khan, Nazir Ahmed, Md. Sahab Uddin, Tapan Behl, Renald Blundell

Publisher : Bentham Science Publishers

N. Javaid, Shah, M. Ajmal, Rasul, A., Chauhdary, Z., Saleem, U., Khan, H., Ahmed, N., Uddin, M. Sahab, Bijo Mathew, Behl, T., and Blundell, R., “Neuroprotective Effects of Ellagic Acid in Alzheimer's Disease: Focus on Underlying Molecular Mechanisms of Therapeutic Potential.”, Current Pharmaceutical Design, Bentham Science Publishers, 2021, 27(34), pp. 3591-3601

Year : 2021

Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach.

Authors : Dr. Bijo Mathew, Nair, Aathira Sujathan; Oh, Jong-Min; Koyiparambath, Vishal Payyalot; Sunil Kumar; Sudevan, Sachithra Thazhathuveedu; Soremekun, Opeyemi; Soliman, Mahmoud E; Khames, Ahmed; Abdelgawad, Mohamed A; Pappachen, Leena K; Kim, Hoon

Publisher : Molecules

A. Sujathan Nair, Oh, J. - M., Koyiparambath, V. Payyalot, Sunil Kumar, Sudevan, S. Thazhathuv, Soremekun, O., Soliman, M. E., Khames, A., Abdelgawad, M. A., Pappachen, L. K., Bijo Mathew, and Kim, H., “Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach.”, Molecules, vol. 26, no. 11, 2021.

Year : 2021

Nanotechnology-Based Approaches and Investigational Therapeutics against COVID-19.

Authors : Dr. Bijo Mathew, Rahman, Md Mominur; Ahmed, Muniruddin; Islam, Mohammad Touhidul; Khan, Md Robin; Sultana, Sharifa; Maeesa, Saila Kabir; Hasan, Sakib; Hossain, Md Abid; Ferdous, Kazi Sayma; Rauf, Abdur; Uddin, Md Sahab

Publisher : Current Pharmaceutical Design

M. Mominur Rahman, Ahmed, M., Islam, M. Touhidul, Khan, M. Robin, Sultana, S., Maeesa, S. Kabir, Hasan, S., Hossain, M. Abid, Ferdous, K. Sayma, Bijo Mathew, Rauf, A., and Uddin, M. Sahab, “Nanotechnology-Based Approaches and Investigational Therapeutics against COVID-19.”, Current Pharmaceutical Design, 2021.

Year : 2021

Therapeutic Potential of Polyphenols in the Management of Diabetic Neuropathy.

Authors : Dr. Bijo Mathew, Kabir, Md Tanvir; Tabassum, Nuzhat; Uddin, Md Sahab; Aziz, Faissal; Behl, Tapan; Rahman, Md Habibur; Akter, Raushanara; Rauf, Abdur; Aleya, Lotfi

Publisher : Evidence based Complementary and Alternative Medicine

M. Tanvir Kabir, Tabassum, N., Uddin, M. Sahab, Aziz, F., Behl, T., Bijo Mathew, Rahman, M. Habibur, Akter, R., Rauf, A., and Aleya, L., “Therapeutic Potential of Polyphenols in the Management of Diabetic Neuropathy.”, Evidence based Complementary and Alternative Medicine, vol. 2021, p. 9940169, 2021.

Year : 2021

Piperazine-substituted chalcones: a new class of MAO-B, AChE, and BACE-1 inhibitors for the treatment of neurological disorders

Authors : Dr. Bijo Mathew, Jong Min Oh, Roua S. Baty, Gaber El-Saber Batiha, Della Grace Thomas Parambi, Nicola Gambacorta, Orazio Nicolotti & Hoon Kim

Publisher : Environmental Science and Pollution Research

Bijo Mathew, Oh, J. Min, Baty, R. S., Batiha, G. El- Saber, Parambi, D. Grace Thom, Gambacorta, N., Nicolotti, O., and Kim, H., “Piperazine-substituted chalcones: a new class of MAO-B, AChE, and BACE-1 inhibitors for the treatment of neurological disorders”, Environmental Science and Pollution Research, 2021, 28(29), pp. 38855-38866.

Year : 2021

Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development.

Authors : Dr. Bijo Mathew, Meduri, Bhagyalalitha; Pujar, Gurubasavaraj Veeranna; Durai Ananda Kumar, T; Akshatha, H S; Sethu, Arun Kumar; Singh, Manisha; Kanagarla, Abhinav

Publisher : ELSEVIER

B. Meduri, Pujar, G. Veeranna, T Kumar, D. Ananda, Akshatha, H. S., Sethu, A. Kumar, Singh, M., Kanagarla, A., and Bijo Mathew, “Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development.”, Eur J Med Chem, vol. 222, p. 113574, 2021.

Year : 2020

Design, Synthesis, and Biological Evaluation of Pyridazinones Containing the (2-Fluorophenyl) Piperazine Moiety as Selective MAO-B Inhibitors

Authors : Dr. Bijo Mathew, Çeçen, Muhammed; Oh, Jong Min; Özdemir, Zeynep; Büyüktuncel, Saliha Ebru; Uysal, Mehtap; Abdelgawad, Mohamed A; Musa, Arafa; Gambacorta, Nicola; Nicolotti, Orazio; Kim, Hoon

Publisher : Molecules, Volume 25, Issue 22

M. Çeçen, Oh, J. Min, Özdemir, Z., Büyüktuncel, S. Ebru, Uysal, M., Abdelgawad, M. A., Musa, A., Gambacorta, N., Nicolotti, O., Mathew, B., and Kim, H., “Design, Synthesis, and Biological Evaluation of Pyridazinones Containing the (2-Fluorophenyl) Piperazine Moiety as Selective MAO-B Inhibitors.”, Molecules, vol. 25, no. 22, p. 5371, 2020.

Year : 2020

Exploring the Therapeutic Potentials of Highly Selective Oxygenated Chalcone Based MAO-B Inhibitors in a Haloperidol-Induced Murine Model of Parkinson’s Disease

Authors : Dr. Bijo Mathew, Parambi, Della Grace Thomas; Saleem, Uzma; Shah, Muhammad Ajmal; Anwar, Fareeha; Ahmad, Bashir; Manzar, Amna; Itzaz, Aqsa; Harilal, Seetha; Uddin, Md Sahab; Kim, Hoon; Bijo Mathew

Publisher : Neurochemical Research

D. Grace Thom Parambi, Saleem, U., Shah, M. Ajmal, Anwar, F., Ahmad, B., Manzar, A., Itzaz, A., Harilal, S., Uddin, M. Sahab, Kim, H., and Bijo Mathew, “Exploring the Therapeutic Potentials of Highly Selective Oxygenated Chalcone Based MAO-B Inhibitors in a Haloperidol-Induced Murine Model of Parkinson’s Disease”, Neurochemical Research, vol. 45, no. 11, pp. 2786 - 2799, 2020.

Year : 2020

A New Potent and Selective Monoamine Oxidase-B Inhibitor with Extended Conjugation in a Chalcone Framework: 1-[4-(Morpholin-4-yl)phenyl]-5-phenylpenta-2,4-dien-1-one.

Authors : Dr. Bijo Mathew, Maliyakkal, Naseer; Eom, Bo Hyun; Heo, Jeong Hyun; Abdullah Almoyad, Mohammad Ali; Thomas Parambi, Della Grace; Gambacorta, Nicola; Nicolotti, Orazio; Beeran, Asmy Appadath; Kim, Hoon; Bijo Mathew

Publisher : ChemMedChem

N. Maliyakkal, Eom, B. Hyun, Heo, J. Hyun, Almoyad, M. Ali Abdull, Parambi, D. Grace Thom, Gambacorta, N., Nicolotti, O., Beeran, A. Appadath, Kim, H., and Bijo Mathew, “A New Potent and Selective Monoamine Oxidase-B Inhibitor with Extended Conjugation in a Chalcone Framework: 1-[4-(Morpholin-4-yl)phenyl]-5-phenylpenta-2,4-dien-1-one.”, ChemMedChem, vol. 15, no. 17, pp. 1629-1633, 2020.

Year : 2020

(Hetero-)(arylidene)arylhydrazides as Multitarget-Directed Monoamine Oxidase Inhibitors

Authors : Dr. Bijo Mathew, Palakkathondi, Ashique; Oh, Jong Min; Dev, Sanal; Rangarajan, T. M.; Kaipakasseri, Swafvan; Kavully, Fathima Sahla; Gambacorta, Nicola; Nicolotti, Orazio; Kim, Hoon; Bijo Mathew

Publisher : American Chemical Society

A. Palakkathondi, Oh, J. Min, Dev, S., Rangarajan, T. M., Kaipakasseri, S., Kavully, F. Sahla, Gambacorta, N., Nicolotti, O., Kim, H., and Bijo Mathew, “(Hetero-)(arylidene)arylhydrazides as Multitarget-Directed Monoamine Oxidase Inhibitors”, ACS Combinatorial ScienceACS Combinatorial Science, vol. 22, no. 11, pp. 592 - 599, 2020.

Year : 2020

Natural Products Database Screening for the Discovery of Naturally Occurring SARS-Cov-2 Spike Glycoprotein Blockers

Authors : Dr. Bijo Mathew, Al-Sehemi, Abdullah G.; Olotu, Fisayo A.; Dev, Sanal; Pannipara, Mehboobali; Soliman, Mahmoud E.; Carradori, Simone; Bijo Mathew

Publisher : ChemistrySelect

A. G. Al-Sehemi, Olotu, F. A., Dev, S., Pannipara, M., Soliman, M. E., Carradori, S., and Bijo Mathew, “Natural Products Database Screening for the Discovery of Naturally Occurring SARS-Cov-2 Spike Glycoprotein Blockers”, ChemistrySelect, vol. 5, pp. 13309-13317, 2020.

Year : 2020

Revisiting the role of brain and peripheral Aβ in the pathogenesis of Alzheimer’s disease

Authors : Dr. Bijo Mathew, Md. Sahab Uddin; Md. Tanvir Kabir; Devesh Tewari; Abdullah Al Mamun; Bijo Mathew; Lotfi Aleya; George E. Barreto; May N. Bin-Jumah; Mohamed M. Abdel-Daim; Ghulam Md Ashraf

Publisher : Journal of the Neurological Sciences

M. Sahab Uddin, Kabir, M. Tanvir, Tewari, D., Mamun, A. Al, Bijo Mathew, Aleya, L., Barreto, G. E., Bin-Jumah, M. N., Abdel-Daim, M. M., and Ashraf, G. Md, “Revisiting the role of brain and peripheral Aβ in the pathogenesis of Alzheimer's disease”, Journal of the Neurological Sciences, vol. 416, p. 116974, 2020.

Year : 2020

Natural compounds from Leeamacrophyllaenhance phagocytosis and promote osteoblastsdifferentiationbyAlp, Type 1 collagen and Osteocalcin gene expression.

Authors : Dr. Bijo Mathew, Raiyan, Sayema; Rahman, Atiar; Al Mamun, Abdullah; Asim, Muzammal Haque; Makki, Arwa; Hajjar, Dina; Alelwani, Walla; Tangpong, Jitbanjong; Bijo Mathew

Publisher : Journal of Biomedical Materials Research Part A

S. Raiyan, Rahman, A., Mamun, A. Al, Asim, M. Haque, Makki, A., Hajjar, D., Alelwani, W., Tangpong, J., and Bijo Mathew, “Natural compounds from Leeamacrophyllaenhance phagocytosis and promote osteoblastsdifferentiationbyAlp, Type 1 collagen and Osteocalcin gene expression.”, Journal of Biomedical Materials Research Part A, 2020.

Year : 2020

Molecular mechanism of zinc neurotoxicity in Alzheimer’s disease

Authors : Dr. Bijo Mathew, Narayanan, Siju Ellickal; Rehuman, Nisha Abdul; Harilal, Seetha; Vincent, Anju; Rajamma, Rajalakshmi Ganesan; Behl, Tapan; Uddin, Md. Sahab; Ashraf, Ghulam Md; Bijo Mathew

Publisher : Environ Sci Pollut Res

S. Ellickal Narayanan, Rehuman, N. Abdul, Harilal, S., Vincent, A., Rajamma, R. Ganesan, Behl, T., Uddin, M. Sahab, Ashraf, G. Md, and Bijo Mathew, “Molecular mechanism of zinc neurotoxicity in Alzheimer’s disease”, Environ Sci Pollut Res, vol. 27, no. 35, pp. 43542 - 43552, 2020.

Year : 2020

Selected 1,3-Benzodioxine-Containing Chalcones as Multipotent Oxidase and Acetylcholinesterase Inhibitors.

Authors : Dr. Bijo Mathew, Jeong, Geum Seok; Kaipakasseri, Swafvan; Lee, Sang Ryong; Marraiki, Najat; Batiha, Gaber El-Saber; Dev, Sanal; Palakkathondi, Ashique; Kavully, Fathima Sahla; Gambacorta, Nicola; Nicolotti, Orazio; Bijo Mathew; Kim, Hoon

Publisher : ChemMedChem

G. Seok Jeong, Kaipakasseri, S., Lee, S. Ryong, Marraiki, N., Batiha, G. El- Saber, Dev, S., Palakkathondi, A., Kavully, F. Sahla, Gambacorta, N., Nicolotti, O., Bijo Mathew, and Kim, H., “Selected 1,3-Benzodioxine-Containing Chalcones as Multipotent Oxidase and Acetylcholinesterase Inhibitors.”, ChemMedChem, vol. 15, pp. 2257-2263, 2020.

Year : 2020

Chalcones: Unearthing their therapeutic possibility as monoamine oxidase B inhibitors

Authors : Dr. Bijo Mathew, Paolo Guglielmi; Bijo Mathew; Daniela Secci; Simone Carradori

Publisher : European Journal of Medicinal Chemistry

P. Guglielmi, Bijo Mathew, Secci, D., and Carradori, S., “Chalcones: Unearthing their therapeutic possibility as monoamine oxidase B inhibitors”, European Journal of Medicinal Chemistry, vol. 205, p. 112650, 2020.

Year : 2020

Synthesis and biological evaluation of new 3(2)-pyridazinone derivatives as non-toxic anti-proliferative compounds against human colon carcinoma HCT116 cells.

Authors : Dr. Bijo Mathew, Özdemir, Zeynep; Utku, Semra; Bijo Mathew; Carradori, Simone; Orlando, Giustino; Di Simone, Simonetta; Alagöz, Mehmet Abdullah; Özçelik, Azime Berna; Uysal, Mehtap; Ferrante, Claudio

Publisher : J Enzyme Inhib Med Chem

Z. Özdemir, Utku, S., Bijo Mathew, Carradori, S., Orlando, G., Di Simone, S., Alagöz, M. Abdullah, Özçelik, A. Berna, Uysal, M., and Ferrante, C., “Synthesis and biological evaluation of new 3(2)-pyridazinone derivatives as non-toxic anti-proliferative compounds against human colon carcinoma HCT116 cells.”, J Enzyme Inhib Med Chem, vol. 35, no. 1, pp. 1100-1109, 2020.

Year : 2020

Privileged Pharmacophore of FDA Approved Drugs in Combination with Chalcone Framework: A New Hope for Alzheimer’s Treatment.

Authors : Dr. Bijo Mathew

Publisher : Comb Chem High Throughput Screen

Bijo Mathew, “Privileged Pharmacophore of FDA Approved Drugs in Combination with Chalcone Framework: A New Hope for Alzheimer's Treatment.”, Comb Chem High Throughput Screen, vol. 23, no. 9, pp. 842-846, 2020.

Year : 2020

Design of enamides as new selective monoamine oxidase-B inhibitors

Authors : Dr. Bijo Mathew, Kavully, Fathima Sahla; Oh, Jong Min; Dev, Sanal; Kaipakasseri, Swafvan; Palakkathondi, Ashique; Vengamthodi, Ajeesh; Abdul Azeez, Rinshana Fathima; Tondo, Anna Rita; Nicolotti, Orazio; Kim, Hoon; Bijo Mathew

Publisher : Journal of Pharmacy and Pharmacology

F. Sahla Kavully, Oh, J. Min, Dev, S., Kaipakasseri, S., Palakkathondi, A., Vengamthodi, A., Azeez, R. Fathima Ab, Tondo, A. Rita, Nicolotti, O., Kim, H., and Bijo Mathew, “Design of enamides as new selective monoamine oxidase-B inhibitors”, Journal of Pharmacy and Pharmacology, vol. 72, pp. 916-926, 2020.

Year : 2020

Molecular Insight into the Therapeutic Promise of Targeting for Alzheimer’s Disease.

Authors : Dr. Bijo Mathew, Mamun, Abdullah Al; Uddin, Md Sahab; Bin Bashar, Md Fahim; Zaman, Sonia; Begum, Yesmin; Bulbul, Israt Jahan; Islam, Md Siddiqul; Sarwar, Md Shahid; Bijo Mathew; Amran, Md Shah; Md Ashraf, Ghulam; Bin-Jumah, May N; Mousa, Shaker A; Abdel-Daim, Mohamed M

Publisher : Oxid Med Cell Longev

A. Al Mamun, Uddin, M. Sahab, Bin Bashar, M. Fahim, Zaman, S., Begum, Y., Bulbul, I. Jahan, Islam, M. Siddiqul, Sarwar, M. Shahid, Bijo Mathew, Amran, M. Shah, Ashraf, G. Md, Bin-Jumah, M. N., Mousa, S. A., and Abdel-Daim, M. M., “Molecular Insight into the Therapeutic Promise of Targeting for Alzheimer's Disease.”, Oxid Med Cell Longev, vol. 2020, p. 5086250, 2020.

Year : 2020

Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors.

Authors : Dr. Bijo Mathew, Oh, Jong Min; Rangarajan, T M; Chaudhary, Reeta; Singh, Rishi Pal; Singh, Manjula; Singh, Raj Pal; Tondo, Anna Rita; Gambacorta, Nicola; Nicolotti, Orazio; Bijo Mathew; Kim, Hoon

Publisher : Molecules

J. Min Oh, Rangarajan, T. M., Chaudhary, R., Singh, R. Pal, Singh, M., Singh, R. Pal, Tondo, A. Rita, Gambacorta, N., Nicolotti, O., Bijo Mathew, and Kim, H., “Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors.”, Molecules, vol. 25, no. 10, 2020.

Year : 2020

Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer’s disease

Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Rahman, Md Ataur; Kabir, Md Tanvir; Behl, Tapan; Bijo Mathew; Perveen, Asma; Barreto, George E; Bin-Jumah, May N; Abdel-Daim, Mohamed M; Ashraf, Ghulam Md

Publisher : IUBMB Life

M. Sahab Uddin, Rahman, M. Ataur, Kabir, M. Tanvir, Behl, T., Bijo Mathew, Perveen, A., Barreto, G. E., Bin-Jumah, M. N., Abdel-Daim, M. M., and Ashraf, G. Md, “Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer's disease.”, IUBMB Life, vol. 72, no. 9, pp. 1843-1855, 2020.

Year : 2020

Emerging Promise of Immunotherapy for Alzheimer’s Disease: A New Hope for the Development of Alzheimer’s Vaccine.

Authors : Dr. Bijo Mathew, Kabir, Md Tanvir; Uddin, Md Sahab; Bijo Mathew; Das, Pankoj Kumar; Perveen, Asma; Ashraf, Ghulam Md

Publisher : Curr Top Med Chem

M. Tanvir Kabir, Uddin, M. Sahab, Bijo Mathew, Das, P. Kumar, Perveen, A., and Ashraf, G. Md, “Emerging Promise of Immunotherapy for Alzheimer's Disease: A New Hope for the Development of Alzheimer's Vaccine.”, Curr Top Med Chem, vol. 20, no. 13, pp. 1214-1234, 2020.

Year : 2020

Combination Drug Therapy for the Management of Alzheimer’s Disease.

Authors : Dr. Bijo Mathew, Kabir, Md Tanvir; Uddin, Md Sahab; Mamun, Abdullah Al; Jeandet, Philippe; Aleya, Lotfi; Mansouri, Rasha A; Ashraf, Ghulam Md; Bijo Mathew; Bin-Jumah, May N; Abdel-Daim, Mohamed M

Publisher : Int J Mol Sci

M. Tanvir Kabir, Uddin, M. Sahab, Mamun, A. Al, Jeandet, P., Aleya, L., Mansouri, R. A., Ashraf, G. Md, Bijo Mathew, Bin-Jumah, M. N., and Abdel-Daim, M. M., “Combination Drug Therapy for the Management of Alzheimer's Disease.”, Int J Mol Sci, vol. 21, no. 9, 2020.

Year : 2020

Fascinating chemo preventive story of wogonin: A chance to hit on the head in cancer treatment.

Authors : Dr. Bijo Mathew, Kumar, Rajesh; Harilal, Seetha; Parambi, Della Grace Thomas; Narayanan, Siju E; Uddin, Md Sahab; Marathakam, Akash; Jose, Jobin; Mathew, Githa Elizabeth; Bijo Mathew

Publisher : Curr Pharm Des

R. Kumar, Harilal, S., Parambi, D. Grace Thom, Narayanan, S. E., Uddin, M. Sahab, Marathakam, A., Jose, J., Mathew, G. Elizabeth, and Bijo Mathew, “Fascinating chemo preventive story of wogonin: A chance to hit on the head in cancer treatment.”, Curr Pharm Des, 2020.

Year : 2020

Novel Anti-Alzheimer’s Therapeutic Molecules Targeting Amyloid Precursor Protein Processing.

Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Kabir, Md Tanvir; Jeandet, Philippe; Bijo Mathew; Ashraf, Ghulam Md; Perveen, Asma; Bin-Jumah, May N; Mousa, Shaker A; Abdel-Daim, Mohamed M

Publisher : Oxid Med Cell Longev

M. Sahab Uddin, Kabir, M. Tanvir, Jeandet, P., Bijo Mathew, Ashraf, G. Md, Perveen, A., Bin-Jumah, M. N., Mousa, S. A., and Abdel-Daim, M. M., “Novel Anti-Alzheimer's Therapeutic Molecules Targeting Amyloid Precursor Protein Processing.”, Oxid Med Cell Longev, vol. 2020, p. 7039138, 2020.

Year : 2020

Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules

Authors : Dr. Bijo Mathew, Seetha Harilal; Jobin Jose; Della Grace Thomas Parambi; Rajesh Kumar; Mazhuvancherry Kesavan Unnikrishnan; Md. Sahab Uddin; Githa Elizabeth Mathew; Rahul Pratap; Akash Marathakam; Bijo Mathew

Publisher : Brain Research Bulletin

S. Harilal, Jose, J., Parambi, D. Grace Thom, Kumar, R., Unnikrishnan, M. Kesavan, Uddin, M. Sahab, Mathew, G. Elizabeth, Pratap, R., Marathakam, A., and Bijo Mathew, “Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules”, Brain Research Bulletin, vol. 160, pp. 121-140, 2020.

Year : 2020

Inhibitions of monoamine oxidases and acetylcholinesterase by 1-methyl, 5-phenyl substituted thiosemicarbazones: Synthesis, biochemical, and computational investigations

Authors : Dr. Bijo Mathew, Githa Elizabeth Mathew; Jong Min Oh; Kumar Mohan; M.V. Kumudhavalli; Sivaraman Jayanthi; Hoon Kim; Bijo Mathew

Publisher : Process Biochemistry

G. Elizabeth Mathew, Oh, J. Min, Mohan, K., Kumudhavalli, M. V., Jayanthi, S., Kim, H., and Bijo Mathew, “Inhibitions of monoamine oxidases and acetylcholinesterase by 1-methyl, 5-phenyl substituted thiosemicarbazones: Synthesis, biochemical, and computational investigations”, Process Biochemistry, vol. 99, pp. 246-253, 2020.

Year : 2020

A Comprehensive Review of Monoamine Oxidase-A Inhibitors in their Syntheses and Potencies.

Authors : Dr. Bijo Mathew, Rehuman, Nisha A; Jat, Rakesh K; Nicolotti, Orazio; Kim, Hoon

Publisher : Comb Chem High Throughput Screen

N. A. Rehuman, Bijo Mathew, Jat, R. K., Nicolotti, O., and Kim, H., “A Comprehensive Review of Monoamine Oxidase-A Inhibitors in their Syntheses and Potencies.”, Comb Chem High Throughput Screen, vol. 23, no. 9, pp. 898-914, 2020.

Year : 2020

TV 3326 for Alzheimer’s dementia: a novel multimodal ChE and MAO inhibitors to mitigate Alzheimer’s-like neuropathology

Authors : Dr. Bijo Mathew, Uddin, Md. Sahab; Kabir, Md. Tanvir; Rahman, Md. Motiar; Bijo Mathew; Shah, Muhammad Ajmal; Ashraf, Ghulam Md

Publisher : Journal of Pharmacy and Pharmacology

M. Sahab Uddin, Kabir, M. Tanvir, Rahman, M. Motiar, Bijo Mathew, Shah, M. Ajmal, and Ashraf, G. Md, “TV 3326 for Alzheimer’s dementia: a novel multimodal ChE and MAO inhibitors to mitigate Alzheimer’s-like neuropathology”, Journal of Pharmacy and Pharmacology, vol. 72, pp. 1001-1012, 2020.

Year : 2020

Estrogen Signaling in Alzheimer’s Disease: Molecular Insights and Therapeutic Targets for Alzheimer’s Dementia.

Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Rahman, Md Motiar; Jakaria, Md; Rahman, Md Sohanur; Hossain, Md Sarwar; Islam, Ariful; Ahmed, Muniruddin; Bijo Mathew; Omar, Ulfat Mohammed; Barreto, George E; Ashraf, Ghulam Md

Publisher : Mol Neurobiol

M. Sahab Uddin, Rahman, M. Motiar, Jakaria, M., Rahman, M. Sohanur, Hossain, M. Sarwar, Islam, A., Ahmed, M., Bijo Mathew, Omar, U. Mohammed, Barreto, G. E., and Ashraf, G. Md, “Estrogen Signaling in Alzheimer's Disease: Molecular Insights and Therapeutic Targets for Alzheimer's Dementia.”, Mol Neurobiol, vol. 57, no. 6, pp. 2654-2670, 2020.

Year : 2020

Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer’s Disease.

Authors : Dr. Bijo Mathew, Narayanan, Siju Ellickal; Sekhar, Nikhila; Rajamma, Rajalakshmi Ganesan; Marathakam, Akash; Al Mamun, Abdullah; Uddin, Md Sahab; Bijo Mathew

Publisher : Curr Protein Pept Sci

S. Ellickal Narayanan, Sekhar, N., Rajamma, R. Ganesan, Marathakam, A., Mamun, A. Al, Uddin, M. Sahab, and Bijo Mathew, “Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer's Disease.”, Curr Protein Pept Sci, vol. 21, no. 12, pp. 1164-1173, 2020.

Year : 2020

Exploring the Promise of Targeting Ubiquitin-Proteasome System to Combat Alzheimer’s Disease.

Authors : Dr. Bijo Mathew, Al Mamun, Abdullah; Uddin, Md Sahab; Kabir, Md Tanvir; Khanum, Sayema; Sarwar, Md Shahid; Bijo Mathew; Rauf, Abdur; Ahmed, Muniruddin; Ashraf, Ghulam Md

Publisher : Neurotox Res

A. Al Mamun, Uddin, M. Sahab, Kabir, M. Tanvir, Khanum, S., Sarwar, M. Shahid, Bijo Mathew, Rauf, A., Ahmed, M., and Ashraf, G. Md, “Exploring the Promise of Targeting Ubiquitin-Proteasome System to Combat Alzheimer's Disease.”, Neurotox Res, vol. 38, no. 1, pp. 8-17, 2020.

Year : 2020

Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer’s Disease.

Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Kabir, Md Tanvir; Niaz, Kamal; Jeandet, Philippe; Clément, Christophe; Bijo Mathew; Rauf, Abdur; Rengasamy, Kannan R R; Sobarzo-Sánchez, Eduardo; Ashraf, Ghulam Md; Aleya, Lotfi

Publisher : Molecules

M. Sahab Uddin, Kabir, M. Tanvir, Niaz, K., Jeandet, P., Clément, C., Bijo Mathew, Rauf, A., Rengasamy, K. R. R., Sobarzo-Sánchez, E., Ashraf, G. Md, and Aleya, L., “Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer's Disease.”, Molecules, vol. 25, no. 6, 2020.

Year : 2020

Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety.

Authors : Dr. Bijo Mathew, Al-Sanea, Mohammad M; Gotina, Lizaveta; Mohamed, Mamdouh Fa; Grace Thomas Parambi, Della; Gomaa, Hesham A M; Bijo Mathew; Youssif, Bahaa G M; Alharbi, Khalid Saad; Elsayed, Zainab M; Abdelgawad, Mohamed A; Eldehna, Wagdy M

Publisher : Drug Des Devel Ther

M. M. Al-Sanea, Gotina, L., Mohamed, M. Fa, Parambi, D. Grace Thom, Gomaa, H. A. M., Bijo Mathew, Youssif, B. G. M., Alharbi, K. Saad, Elsayed, Z. M., Abdelgawad, M. A., and Eldehna, W. M., “Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety.”, Drug Des Devel Ther, vol. 14, pp. 497-508, 2020.

Year : 2020

Exploring the Multifunctional Neuroprotective Promise of Rasagiline Derivatives for Multi-Dysfunctional Alzheimer’s Disease.

Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Kabir, Md Tanvir; Rahman, Md Habibur; Alim, Md Abdul; Rahman, Md Motiar; Khatkar, Anurag; Al Mamun, Abdullah; Rauf, Abdur; Bijo Mathew; Ashraf, Ghulam Md

Publisher : Curr Pharm Des

M. Sahab Uddin, Kabir, M. Tanvir, Rahman, M. Habibur, Alim, M. Abdul, Rahman, M. Motiar, Khatkar, A., Mamun, A. Al, Rauf, A., Bijo Mathew, and Ashraf, G. Md, “Exploring the Multifunctional Neuroprotective Promise of Rasagiline Derivatives for Multi-Dysfunctional Alzheimer's Disease.”, Curr Pharm Des, vol. 26, no. 37, pp. 4690-4698, 2020.

Year : 2020

Emerging promise of sulforaphane-mediated Nrf2 signaling cascade against neurological disorders.

Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Mamun, Abdullah Al; Jakaria, Md; Thangapandiyan, Shanmugam; Ahmad, Jamil; Rahman, Md Ataur; Bijo Mathew; Abdel-Daim, Mohamed M; Aleya, Lotfi

Publisher : Sci Total Environ

M. Sahab Uddin, Mamun, A. Al, Jakaria, M., Thangapandiyan, S., Ahmad, J., Rahman, M. Ataur, Bijo Mathew, Abdel-Daim, M. M., and Aleya, L., “Emerging promise of sulforaphane-mediated Nrf2 signaling cascade against neurological disorders.”, Sci Total Environ, vol. 707, p. 135624, 2020.

Year : 2020

Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery.

Authors : Dr. Bijo Mathew, Zahin, Nuzhat; Anwar, Raihanatul; Tewari, Devesh; Kabir, Md Tanvir; Sajid, Amin; Bijo Mathew; Uddin, Md Sahab; Aleya, Lotfi; Abdel-Daim, Mohamed M

Publisher : Environ Sci Pollut Res Int

N. Zahin, Anwar, R., Tewari, D., Kabir, M. Tanvir, Sajid, A., Bijo Mathew, Uddin, M. Sahab, Aleya, L., and Abdel-Daim, M. M., “Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery.”, Environ Sci Pollut Res Int, vol. 27, no. 16, pp. 19151-19168, 2020.

Year : 2020

Studies on the interaction between HSA and new halogenated metformin derivatives: influence of lipophilic groups in the binding ability.

Authors : Dr. Bijo Mathew, Chaves, Otávio Augusto; Bijo Mathew; Parambi, Della Grace Thomas; C S de Oliveira, Cosme Henrique; Cesarin-Sobrinho, Dari; Lakshminarayanan, Balasubramanian; Najeeb, Sadiya; Nafna, E K; Marathakam, Akash; Uddin, Md Sahab; Joy, Monu; Carlos Netto-Ferreira, José

Publisher : J Biomol Struct Dyn

O. Augusto Chaves, Bijo Mathew, Parambi, D. Grace Thom, de Oliveira, C. Henrique C., Cesarin-Sobrinho, D., Lakshminarayanan, B., Najeeb, S., Nafna, E. K., Marathakam, A., Uddin, M. Sahab, Joy, M., and Netto-Ferreira, J. Carlos, “Studies on the interaction between HSA and new halogenated metformin derivatives: influence of lipophilic groups in the binding ability.”, J Biomol Struct Dyn, vol. 38, no. 7, pp. 2128-2140, 2020.

Year : 2020

Toxic tau: structural origins of tau aggregation in Alzheimer’s disease.

Authors : Dr. Bijo Mathew, Mamun, Abdullah Al; Uddin, Md Sahab; Bijo Mathew; Ashraf, Ghulam Md

Publisher : Neural Regen Res

A. Al Mamun, Uddin, M. Sahab, Bijo Mathew, and Ashraf, G. Md, “Toxic tau: structural origins of tau aggregation in Alzheimer's disease.”, Neural Regen Res, vol. 15, no. 8, pp. 1417-1420, 2020.

Year : 2020

Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer’s disease.

Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Kabir, Md Tanvir; Tewari, Devesh; Bijo Mathew; Aleya, Lotfi

Publisher : Sci Total Environ

M. Sahab Uddin, Kabir, M. Tanvir, Tewari, D., Bijo Mathew, and Aleya, L., “Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer's disease.”, Sci Total Environ, vol. 700, p. 134836, 2020.

Year : 2020

Inhibitors of Monoamine Oxidase and Acetylcholinesterase as a Front Runner in CNS Drug Discovery

Authors : Dr. Bijo Mathew, Kim, H

Publisher : Comb Chem High Throughput Screen

Bijo Mathew and Kim, H., “Inhibitors of Monoamine Oxidase and Acetylcholinesterase as a Front Runner in CNS Drug Discovery.”, Comb Chem High Throughput Screen, vol. 23, no. 9, pp. 834-835, 2020.

Year : 2020

An Environment-friendly Synthesis of Piperonal Chalcones and Their Cytotoxic and Antioxidant Evaluation

Authors : Dr. Bijo Mathew, Dev, Sanal; Thomas Parambi, Della Grace; Baby, Bency; Mathew, Githa Elizabeth; Omnia Magdy, Hendawy; Joy, Monu; Sudev, Shine; Bijo Mathew

Publisher : Letters in Drug Design & Discovery

S. Dev, Parambi, D. Grace Thom, Baby, B., Mathew, G. Elizabeth, Magdy, H. Omnia, Joy, M., Sudev, S., and Bijo Mathew, “An Environment-friendly Synthesis of Piperonal Chalcones and Their Cytotoxic and Antioxidant Evaluation”, Letters in Drug Design & Discovery, vol. 17, pp. 138-144, 2020.

Year : 2020

Magnetic nanoparticles for hyperthermia in cancer treatment: an emerging tool.

Authors : Dr. Bijo Mathew, Jose, Jobin; Kumar, Rajesh; Harilal, Seetha; Mathew, Githa Elizabeth; Parambi, Della Grace Thomas; Prabhu, Ankitha; Uddin, Md Sahab; Aleya, Lotfi; Kim, Hoon; Bijo Mathew

Publisher : Environ Sci Pollut Res Int

J. Jose, Kumar, R., Harilal, S., Mathew, G. Elizabeth, Parambi, D. Grace Thom, Prabhu, A., Uddin, M. Sahab, Aleya, L., Kim, H., and Bijo Mathew, “Magnetic nanoparticles for hyperthermia in cancer treatment: an emerging tool.”, Environ Sci Pollut Res Int, vol. 27, no. 16, pp. 19214-19225, 2020.

Year : 2019

Emerging therapeutic potentials of dual-acting MAO and AChE inhibitors in Alzheimer’s and Parkinson’s diseases.

Authors : Dr. Bijo Mathew, Bijo Mathew; Parambi, Della G T; Mathew, Githa E; Uddin, Md Sahab; Inasu, Sini T; Kim, Hoon; Marathakam, Akash; Unnikrishnan, Mazhuvancherry Kesavan; Carradori, Simone

Publisher : Arch Pharm (Weinheim)

Bijo Mathew, Parambi, D. G. T., Mathew, G. E., Uddin, M. Sahab, Inasu, S. T., Kim, H., Marathakam, A., Unnikrishnan, M. Kesavan, and Carradori, S., “Emerging therapeutic potentials of dual-acting MAO and AChE inhibitors in Alzheimer's and Parkinson's diseases.”, Arch Pharm (Weinheim), vol. 352, no. 11, p. e1900177, 2019.

Year : 2019

Design, synthesis and biological evaluation of oxygenated chalcones as potent and selective MAO-B inhibitors.

Authors : Dr. Bijo Mathew, Parambi, Della Grace Thomas; Oh, Jong Min; Baek, Seung Cheol; Lee, Jae Pil; Tondo, Anna Rita; Nicolotti, Orazio; Kim, Hoon; Bijo Mathew

Publisher : Bioorg Chem

D. Grace Thom Parambi, Oh, J. Min, Baek, S. Cheol, Lee, J. Pil, Tondo, A. Rita, Nicolotti, O., Kim, H., and Bijo Mathew, “Design, synthesis and biological evaluation of oxygenated chalcones as potent and selective MAO-B inhibitors.”, Bioorg Chem, vol. 93, p. 103335, 2019.

Year : 2019

NMDA Receptor Antagonists: Repositioning of Memantine as a Multitargeting Agent for Alzheimer’s Therapy.

Authors : Dr. Bijo Mathew, Kabir, Md Tanvir; Sufian, Mohammad A; Uddin, Md Sahab; Begum, Mst Marium; Akhter, Shammi; Islam, Ariful; Islam, Md Siddiqul; Amran, Md Shah; Md Ashraf, Ghulam

Publisher : Curr Pharm Des

M. Tanvir Kabir, Sufian, M. A., Uddin, M. Sahab, Begum, M. Marium, Akhter, S., Islam, A., Bijo Mathew, Islam, M. Siddiqul, Amran, M. Shah, and Ashraf, G. Md, “NMDA Receptor Antagonists: Repositioning of Memantine as a Multitargeting Agent for Alzheimer's Therapy.”, Curr Pharm Des, vol. 25, no. 33, pp. 3506-3518, 2019.

Year : 2019

Ethyl Acetohydroxamate Incorporated Chalcones: Unveiling a Novel Class of Chalcones for Multitarget Monoamine Oxidase-B Inhibitors Against Alzheimer’s Disease.

Authors : Dr. Bijo Mathew, Baek, Seung Cheol; Lee, Jae Pil; Rangarajan, T M; Singh, Rishi Pal; Singh, Manjula; Mangiatordi, Giuseppe Felice; Nicolotti, Orazio; Kim, Hoon

Publisher : CNS Neurol Disord Drug Targets

S. Cheol Baek, Lee, J. Pil, Rangarajan, T. M., Singh, R. Pal, Singh, M., Mangiatordi, G. Felice, Nicolotti, O., Kim, H., and Bijo Mathew, “Ethyl Acetohydroxamate Incorporated Chalcones: Unveiling a Novel Class of Chalcones for Multitarget Monoamine Oxidase-B Inhibitors Against Alzheimer's Disease.”, CNS Neurol Disord Drug Targets, vol. 18, no. 8, pp. 643-654, 2019.

Year : 2019

Advancements in nanotherapeutics for Alzheimer’s disease: current perspectives.

Authors : Dr. Bijo Mathew, Harilal, Seetha; Jose, Jobin; Parambi, Della Grace Thomas; Kumar, Rajesh; Mathew, Githa Elizabeth; Uddin, Md Sahab; Kim, Hoon

Publisher : J Pharm Pharmacol

S. Harilal, Jose, J., Parambi, D. Grace Thom, Kumar, R., Mathew, G. Elizabeth, Uddin, M. Sahab, Kim, H., and Bijo Mathew, “Advancements in nanotherapeutics for Alzheimer's disease: current perspectives.”, J Pharm Pharmacol, vol. 71, no. 9, pp. 1370-1383, 2019.

Year : 2019

Aptamers in Drug Design: An Emerging Weapon to Fight a Losing Battle.

Authors : Dr. Bijo Mathew, Jose, Jobin; Thomas, Aaron Mathew; Mendonsa, Darewin; Al-Sanea, Mohammad M; Uddin, Md Sahab; Parambi, Della Grace Thomas; Charyulu, R Narayana; Bijo Mathew

Publisher : Curr Drug Targets

J. Jose, Thomas, A. Mathew, Mendonsa, D., Al-Sanea, M. M., Uddin, M. Sahab, Parambi, D. Grace Thom, R Charyulu, N., and Bijo Mathew, “Aptamers in Drug Design: An Emerging Weapon to Fight a Losing Battle.”, Curr Drug Targets, vol. 20, no. 16, pp. 1624-1635, 2019.

Year : 2019

Anti-inflammatory effect of synthesized indole-based chalcone (2E)-3-(4-bromophenyl)-1-(1-indol-3-yl) prop-2-en-1-one: an and studies.

Authors : Dr. Bijo Mathew, Sasidharan, Rani; Sreedharannair Leelabaiamma, Manju; Mohanan, Ratheesh; Jose, Svenia P; Bijo Mathew; Sukumaran, Sandya

Publisher : Immunopharmacol Immunotoxicol

R. Sasidharan, Leelabaiamma, M. Sreedharan, Mohanan, R., Jose, S. P., Bijo Mathew, and Sukumaran, S., “Anti-inflammatory effect of synthesized indole-based chalcone (2E)-3-(4-bromophenyl)-1-(1-indol-3-yl) prop-2-en-1-one: an and studies.”, Immunopharmacol Immunotoxicol, vol. 41, no. 6, pp. 568-576, 2019.

Year : 2019

Exploring the new horizons of drug repurposing: A vital tool for turning hard work into smart work.

Authors : Dr. Bijo Mathew, Kumar, Rajesh; Harilal, Seetha; Gupta, Sheeba Varghese; Jose, Jobin; Thomas Parambi, Della Grace; Uddin, Md Sahab; Shah, Muhammad Ajmal; Bijo Mathew

Publisher : Eur J Med Chem

R. Kumar, Harilal, S., Gupta, S. Varghese, Jose, J., Parambi, D. Grace Thom, Uddin, M. Sahab, Shah, M. Ajmal, and Bijo Mathew, “Exploring the new horizons of drug repurposing: A vital tool for turning hard work into smart work.”, Eur J Med Chem, vol. 182, p. 111602, 2019.

Year : 2019

Cholinesterase Inhibitors for Alzheimer’s Disease: Multitargeting Strategy Based on Anti-Alzheimer’s Drugs Repositioning.

Authors : Dr. Bijo Mathew, Kabir, Md Tanvir; Uddin, Md Sahab; Begum, Mst Marium; Thangapandiyan, Shanmugam; Rahman, Md Sohanur; Aleya, Lotfi; Bijo Mathew; Ahmed, Muniruddin; Barreto, George E; Ashraf, Ghulam Md

Publisher : Curr Pharm Des

M. Tanvir Kabir, Uddin, M. Sahab, Begum, M. Marium, Thangapandiyan, S., Rahman, M. Sohanur, Aleya, L., Bijo Mathew, Ahmed, M., Barreto, G. E., and Ashraf, G. Md, “Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning.”, Curr Pharm Des, vol. 25, no. 33, pp. 3519-3535, 2019.

Year : 2019

Perspective Design of Chalcones for the Management of CNS Disorders: A Mini-Review.

Authors : Dr. Bijo Mathew, Bijo Mathew; Parambi, Della Grace Thomas; Sivasankarapillai, Vishnu Sankar; Uddin, Md Sahab; Suresh, Jerad; Mathew, Githa Elizabeth; Joy, Monu; Marathakam, Akash; Gupta, Sheeba Varghese

Publisher : CNS Neurol Disord Drug Targets

Bijo Mathew, Parambi, D. Grace Thom, Sivasankarapillai, V. Sankar, Uddin, M. Sahab, Suresh, J., Mathew, G. Elizabeth, Joy, M., Marathakam, A., and Gupta, S. Varghese, “Perspective Design of Chalcones for the Management of CNS Disorders: A Mini-Review.”, CNS Neurol Disord Drug Targets, vol. 18, no. 6, pp. 432-445, 2019.

Year : 2019

Cholinesterase Inhibitory Activities of Selected Halogenated Thiophene Chalcones.

Authors : Dr. Bijo Mathew, Parambi, Della G T; Aljoufi, Fakhrya; Murugaiyah, Vikneswaran; Mathew, Githa E; Dev, Sanal; Lakshminarayanan, Balasubramanain; Hendawy, Omnia M; Bijo Mathew

Publisher : Cent Nerv Syst Agents Med Chem

D. G. T. Parambi, Aljoufi, F., Murugaiyah, V., Mathew, G. E., Dev, S., Lakshminarayanan, B., Hendawy, O. M., and Bijo Mathew, “Cholinesterase Inhibitory Activities of Selected Halogenated Thiophene Chalcones.”, Cent Nerv Syst Agents Med Chem, vol. 19, no. 1, pp. 67-71, 2019.

Year : 2019

Ethoxylated Head of Chalcones as a New Class of Multi-Targeted MAO Inhibitors

Authors : Dr. Bijo Mathew, Lakshminarayanan, Balasubramanian; Baek, Seung Cheol; Lee, Jae Pil; Kannappan, Nagappan; Mangiatordi, Giuseppe Felice; Nicolotti, Orazio; Subburaju, Thillainayagam; Kim, Hoon; Bijo Mathew

Publisher : ChemistrySelect

B. Lakshminarayanan, Baek, S. Cheol, Lee, J. Pil, Kannappan, N., Mangiatordi, G. Felice, Nicolotti, O., Subburaju, T., Kim, H., and Bijo Mathew, “Ethoxylated Head of Chalcones as a New Class of Multi-Targeted MAO Inhibitors”, ChemistrySelect, vol. 4, pp. 6614-6619, 2019.

Year : 2019

Melatonin in Alzheimer’s Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer’s Neuropathology

Authors : Dr. Bijo Mathew, Hossain, Md Farhad; Uddin, Md Sahab; Uddin, G M Sala; Sumsuzzman, Dewan Md; Islam, Md Siddiqul; Barreto, George E; Ashraf, Ghulam Md

Publisher : Mol Neurobiol

M. Farhad Hossain, Uddin, M. Sahab, Uddin, G. M. Sala, Sumsuzzman, D. Md, Islam, M. Siddiqul, Barreto, G. E., Bijo Mathew, and Ashraf, G. Md, “Melatonin in Alzheimer's Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer's Neuropathology.”, Mol Neurobiol, vol. 56, no. 12, pp. 8255-8276, 2019.

Year : 2019

Natural inhibitors on airway mucin: Molecular insight into the therapeutic potential targeting MUC5AC expression and production.

Authors : Dr. Bijo Mathew, Samsuzzaman, Md; Uddin, Md Sahab; Shah, Muhammad Ajmal; Bijo Mathew

Publisher : Life Sci

M. Samsuzzaman, Uddin, M. Sahab, Shah, M. Ajmal, and Bijo Mathew, “Natural inhibitors on airway mucin: Molecular insight into the therapeutic potential targeting MUC5AC expression and production.”, Life Sci, vol. 231, p. 116485, 2019.

Year : 2019

In Vitro Study of the Interaction Between HSA and 4-Bromoindolylchalcone, a Potent Human MAO-B Inhibitor: Spectroscopic and Molecular Modeling Studies

Authors : Dr. Bijo Mathew, Chaves, Otávio Augusto; Sasidharan, Rani; dos Santos de Oliveira, Cosme H. C.; Manju, Sreedharannair Leelabaiamma; Joy, Monu; Bijo Mathew; Netto-Ferreira, José Carlos

Publisher : ChemistrySelect

O. Augusto Chaves, Sasidharan, R., de Oliveira, C. H. C. dos, Manju, S. Leelabaiam, Joy, M., Bijo Mathew, and Netto-Ferreira, J. Carlos, “In Vitro Study of the Interaction Between HSA and 4-Bromoindolylchalcone, a Potent Human MAO-B Inhibitor: Spectroscopic and Molecular Modeling Studies”, ChemistrySelect, vol. 4, pp. 1007-1014, 2019.

Year : 2019

Fe O nanoparticles mediated synthesis of novel spirooxindole-dihydropyrimidinone molecules as Hsp90 inhibitors.

Authors : Dr. Bijo Mathew, Maddela, Srinubabu; Makula, Ajitha; Galigniana, Mario D; Parambi, Della G T; Federicci, Fernando; Mazaira, Gisela; Hendawy, Omnia M; Dev, Sanal; Mathew, Githa E; Bijo Mathew

Publisher : Arch Pharm (Weinheim)

S. Maddela, Makula, A., Galigniana, M. D., Parambi, D. G. T., Federicci, F., Mazaira, G., Hendawy, O. M., Dev, S., Mathew, G. E., and Bijo Mathew, “Fe O nanoparticles mediated synthesis of novel spirooxindole-dihydropyrimidinone molecules as Hsp90 inhibitors.”, Arch Pharm (Weinheim), vol. 352, no. 1, p. e1800174, 2019.

Year : 2019

Potent and highly selective dual-targeting monoamine oxidase-B inhibitors: Fluorinated chalcones of morpholine versus imidazole

Authors : Dr. Bijo Mathew, Bijo Mathew; Baek, Seung C; Thomas Parambi, Della G; Lee, Jae P; Mathew, Githa E; Jayanthi, Sivaraman; Vinod, Devaraji; Rapheal, Clariya; Devikrishna, Vinod; Kondarath, Shahin Shad; Uddin, Md Sahab; Kim, Hoon

Publisher : Arch Pharm (Weinheim)

Bijo Mathew, Baek, S. C., Parambi, D. G. Thomas, Lee, J. P., Mathew, G. E., Jayanthi, S., Vinod, D., Rapheal, C., Devikrishna, V., Kondarath, S. Shad, Uddin, M. Sahab, and Kim, H., “Potent and highly selective dual-targeting monoamine oxidase-B inhibitors: Fluorinated chalcones of morpholine versus imidazole.”, Arch Pharm (Weinheim), vol. 352, no. 4, p. e1800309, 2019.

Year : 2019

Silicon Quantum Dots: Promising Theranostic Probes for the Future.

Authors : Dr. Bijo Mathew, Sivasankarapillai, Vishnu Sankar; Jose, Jobin; Shanavas, Muhammad Salman; Marathakam, Akash; Uddin, Md Sahab; Bijo Mathew

Publisher : Curr Drug Targets

V. Sankar Sivasankarapillai, Jose, J., Shanavas, M. Salman, Marathakam, A., Uddin, M. Sahab, and Bijo Mathew, “Silicon Quantum Dots: Promising Theranostic Probes for the Future.”, Curr Drug Targets, vol. 20, no. 12, pp. 1255-1263, 2019.

Year : 2019

Nootropic and Anti-Alzheimer’s Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer’s Neuropathology

Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Al Mamun, Abdullah; Kabir, Md Tanvir; Jakaria, Md; Bijo Mathew; Barreto, George E; Ashraf, Ghulam Md

Publisher : Mol Neurobiol

M. Sahab Uddin, Mamun, A. Al, Kabir, M. Tanvir, Jakaria, M., Bijo Mathew, Barreto, G. E., and Ashraf, G. Md, “Nootropic and Anti-Alzheimer's Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer's Neuropathology.”, Mol Neurobiol, vol. 56, no. 7, pp. 4925-4944, 2019.

Year : 2018

Imidazole bearing chalcones as a new class of monoamine oxidase inhibitors.

Authors : Dr. Bijo Mathew, Sasidharan, Rani; Baek, Seung Cheol; Sreedharannair Leelabaiamma, Manju; Kim, Hoon

Publisher : Biomed Pharmacothe

R. Sasidharan, Baek, S. Cheol, Leelabaiamma, M. Sreedharan, Kim, H., and Bijo Mathew, “Imidazole bearing chalcones as a new class of monoamine oxidase inhibitors.”, Biomed Pharmacother, vol. 106, pp. 8-13, 2018.

Year : 2018

Virtual combinatorial library design, synthesis and in vitro anticancer assessment of -2-amino-3-cyanopyridine derivatives

Authors : Dr. Bijo Mathew, Dev S.; Dhaneshwar SR;

Publisher : Combinatorial Chemistry and High Throughput Screening. [Bentham Science]

D. S., ,, and Bijo Mathew, “Virtual combinatorial library design, synthesis and in vitro anticancer assessment of -2-amino-3-cyanopyridine derivatives”, Combinatorial Chemistry and High Throughput Screening. [Bentham Science], vol. 21, pp. 138-148, 2018.

Year : 2018

Structural and optical profile of a multifunctionalized 2-pyridone derivative in a crystal engineering perspective.

Authors : Dr. Bijo Mathew, Joy, Monu; Anabha, E R; Gopi, Subash; Kumar S, Ajeesh; Mathews, Annie

Publisher : Acta Crystallogr C Struct Chem

M. Joy, Anabha, E. R., Gopi, S., Bijo Mathew, S, A. Kumar, and Mathews, A., “Structural and optical profile of a multifunctionalized 2-pyridone derivative in a crystal engineering perspective.”, Acta Crystallogr C Struct Chem, vol. 74, no. Pt 7, pp. 807-815, 2018.

Year : 2018

Selected aryl thiosemicarbazones as a new class of multi-targeted monoamine oxidase inhibitors.

Authors : Dr. Bijo Mathew, Bijo Mathew; Baek, Seung Cheol; Grace Thomas Parambi, Della; Pil Lee, Jae; Joy, Monu; Annie Rilda, P R; Randev, Rugma V; Nithyamol, P; Vijayan, Vijitha; Inasu, Sini T; Mathew, Githa Elizabeth; Lohidakshan, Krishnakumar K; Kumar Krishnan, Girish; Kim, Hoon

Publisher : Medchemcomm

Bijo Mathew, Baek, S. Cheol, Parambi, D. Grace Thom, Lee, J. Pil, Joy, M., Rilda, P. R. Annie, Randev, R. V., Nithyamol, P., Vijayan, V., Inasu, S. T., Mathew, G. Elizabeth, Lohidakshan, K. K., Krishnan, G. Kumar, and Kim, H., “Selected aryl thiosemicarbazones as a new class of multi-targeted monoamine oxidase inhibitors.”, Medchemcomm, vol. 9, no. 11, pp. 1871-1881, 2018.

Year : 2018

Dual acting Isatin-Heterocyclic Hybrids: Recent Highlights as Promising Pharmacological Agents

Authors : Dr. Bijo Mathew

Publisher : Volume 15

Bijo Mathew, “Dual acting Isatin-Heterocyclic Hybrids: Recent Highlights as Promising Pharmacological Agents”, vol. 15, 2018.

Year : 2018

Discovery of new class of methoxy carrying isoxazole derivatives as COX-II inhibitors: Investigation of a detailed molecular dynamics study

Authors : Dr. Bijo Mathew, Monu Joy; Ahmed A. Elrashedy; Bijo Mathew; Ashona Singh Pillay; Annie Mathews; Sanal Dev; Mahmoud E.S. Soliman; C. Sudarsanakumar

Publisher : Journal of Molecular Structure

M. Joy, Elrashedy, A. A., Bijo Mathew, Pillay, A. Singh, Mathews, A., Dev, S., Soliman, M. E. S., and Sudarsanakumar, C., “Discovery of new class of methoxy carrying isoxazole derivatives as COX-II inhibitors: Investigation of a detailed molecular dynamics study”, Journal of Molecular Structure, vol. 1157, pp. 19-28, 2018.

Year : 2018

Discovery of potent and reversible MAO-B inhibitors as furanochalcones

Authors : Dr. Bijo Mathew, Jerad Suresh; Seung Cheol Baek; Surya Parakkot Ramakrishnan; Hoon Kim

Publisher : International Journal of Biological Macromolecules

J. Suresh, Baek, S. Cheol, Ramakrishnan, S. Parakkot, Kim, H., and Bijo Mathew, “Discovery of potent and reversible MAO-B inhibitors as furanochalcones”, International Journal of Biological Macromolecules, vol. 108, pp. 660-664, 2018.

Year : 2018

Introduction of fluorinated environment on metformin. Evaluation of its serum-albumin interaction with molecular modeling studies

Authors : Dr. Bijo Mathew, Otávio Augusto Chaves; Monu Joy; Krishnakumar K. Lohidakshan; Akash Marathakam; José Carlos Netto-Ferreira

Publisher : Journal of Molecular Liquids

O. Augusto Chaves, Bijo Mathew, Joy, M., Lohidakshan, K. K., Marathakam, A., and Netto-Ferreira, J. Carlos, “Introduction of fluorinated environment on metformin. Evaluation of its serum-albumin interaction with molecular modeling studies”, Journal of Molecular Liquids, vol. 260, pp. 186-194, 2018.

Year : 2018

Structural features of Safinamide: A combined Hirshfeld surface analysis & quantum chemical treatment

Authors : Dr. Bijo Mathew, Monu Joy; Bijo Mathew; C. Sudarsanakumar

Publisher : Chemical Data Collections

M. Joy, Bijo Mathew, and Sudarsanakumar, C., “Structural features of Safinamide: A combined Hirshfeld surface analysis & quantum chemical treatment”, Chemical Data Collections, vol. 17-18, pp. 404-414, 2018.

Year : 2017

Monoamine oxidase inhibitory activity of methoxy-substituted chalcones.

Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Ucar, Gülberk; Joy, Monu; Nafna, E K; Lohidakshan, Krishnakumar K; Suresh, Jerad

Publisher : Int J Biol Macromol

Bijo Mathew, Mathew, G. Elizabeth, Ucar, G., Joy, M., Nafna, E. K., Lohidakshan, K. K., and Suresh, J., “Monoamine oxidase inhibitory activity of methoxy-substituted chalcones.”, Int J Biol Macromol, vol. 104, no. Pt A, pp. 1321-1329, 2017.

Year : 2017

Pharmacophore-Based 3D-QSAR Analysis of Thienyl Chalcones as a New Class of Human MAO-B Inhibitors: Investigation of Combined Quantum Chemical and Molecular Dynamics Approach.

Authors : Dr. Bijo Mathew, Pharma; Adeniyi, Adebayo A; Dev, Sanal; Joy, Monu; Ucar, Gülberk; Mathew, Githa Elizabeth; Singh-Pillay, Ashona; Soliman, Mahmoud E S

Publisher : J Phys Chem B

Bijo Mathew, Adeniyi, A. A., Dev, S., Joy, M., Ucar, G., Mathew, G. Elizabeth, Singh-Pillay, A., and Soliman, M. E. S., “Pharmacophore-Based 3D-QSAR Analysis of Thienyl Chalcones as a New Class of Human MAO-B Inhibitors: Investigation of Combined Quantum Chemical and Molecular Dynamics Approach.”, J Phys Chem B, vol. 121, no. 6, pp. 1186-1203, 2017.

Year : 2017

Molecular modeling of drug-pathophysiological Mtb protein targets: Synthesis of some 2-thioxo-1, 3-thiazolidin-4-one derivatives as anti-tubercular agents

Authors : Dr. Bijo Mathew, K.M. Noorulla; Ayyadurai Jerad Suresh; Vinod Devaraji; Devi Umesh

Publisher : Journal of Molecular Structure

K. M. Noorulla, Suresh, A. Jerad, Devaraji, V., Bijo Mathew, and Umesh, D., “Molecular modeling of drug-pathophysiological Mtb protein targets: Synthesis of some 2-thioxo-1, 3-thiazolidin-4-one derivatives as anti-tubercular agents”, Journal of Molecular Structure, vol. 1147, pp. 682-696, 2017.

Year : 2017

Spectroscopic, zeta potential and molecular docking analysis on the interaction between human serum albumin and halogenated thienyl chalcones

Authors : Dr. Bijo Mathew, Otávio Augusto Chaves; Dari Cesarin-Sobrinho; Balasubramanian Lakshminarayanan; Monu Joy; Githa Elizabeth Mathew; Jerad Suresh; José Carlos Netto-Ferreira

Publisher : Journal of Molecular Liquids

O. Augusto Chaves, Bijo Mathew, Cesarin-Sobrinho, D., Lakshminarayanan, B., Joy, M., Mathew, G. Elizabeth, Suresh, J., and Netto-Ferreira, J. Carlos, “Spectroscopic, zeta potential and molecular docking analysis on the interaction between human serum albumin and halogenated thienyl chalcones”, Journal of Molecular Liquids, vol. 242, pp. 1018-1026, 2017.

Year : 2017

Synthetic Approaches to Various Class of Topoisomerase II Inhibitors

Authors : Dr. Bijo Mathew, Sanal Dev; Nishad Gabhe; S.R. Dhaneshwar; Monu Joy

Publisher : Mini-Reviews in Organic Chemistry

S. Dev, Gabhe, N., Dhaneshwar, S. R., Joy, M., and Bijo Mathew, “Synthetic Approaches to Various Class of Topoisomerase II Inhibitors”, Mini-Reviews in Organic Chemistry, vol. 14, pp. 357-374, 2017.

Year : 2017

Probing mechanism of α-formylketene dithioacetal towards the facile formation of functionalized pyrimidines: A structural approach

Authors : Dr. Bijo Mathew, Monu Joy; Adebayo A. Adeniyi; Annie Mathews; Bijo Mathew; S. Prasanth; Mohmoud E.S. Soliman; Jalaja J. Malayan; E.R. Anabha

Publisher : Journal of Molecular Structure

M. Joy, Adeniyi, A. A., Mathews, A., Bijo Mathew, Prasanth, S., Soliman, M. E. S., Malayan, J. J., and Anabha, E. R., “Probing mechanism of α-formylketene dithioacetal towards the facile formation of functionalized pyrimidines: A structural approach”, Journal of Molecular Structure, vol. 1127, pp. 498-510, 2017.

Year : 2017

Anti-oxidant behavior of functionalized chalcone-a combined quantum chemical and crystallographic structural investigation

Authors : Dr. Bijo Mathew, Adeniyi, Adebayo A.; Joy, Monu; Mathew, Githa Elizabeth; Singh-Pillay, Ashona; Sudarsanakumar, C.; Soliman, Mahmoud E. S.; Suresh, Jerad

Publisher : Journal of Molecular Structure

Bijo Mathew, Adeniyi, A. A., Joy, M., Mathew, G. Elizabeth, Singh-Pillay, A., Sudarsanakumar, C., Soliman, M. E. S., and Suresh, J., “Anti-oxidant behavior of functionalized chalcone-a combined quantum chemical and crystallographic structural investigation”, Journal of Molecular Structure, vol. 1146, pp. 301-308, 2017.

Year : 2017

Characterization of Thienylchalcones as hMAO-B Inhibitors: Synthesis, Biochemistry and Molecular Dynamics Studies

Authors : Dr. Bijo Mathew, Bijo Mathew; Ucar, Gülberk; Rapheal, Clariya; Mathew, Githa E.; Joy, Monu; Machaba, Kgothatso E.; Soliman, Mahmoud E. S.

Publisher : ChemistrySelect, Volume 2

Bijo Mathew, Ucar, G., Rapheal, C., Mathew, G. E., Joy, M., Machaba, K. E., and Soliman, M. E. S., “Characterization of Thienylchalcones as hMAO-B Inhibitors: Synthesis, Biochemistry and Molecular Dynamics Studies”, ChemistrySelect, vol. 2, pp. 11113-11119, 2017.

Year : 2017

Molecular Docking, Synthesis and CNS Activity of Some Novel 1, 4-Benzodiazepine Derivatives

Authors : Dr. Bijo Mathew, Sunil S. Menghani*; Rupesh Chikhale; Amit Pant; Bijo Mathew; Pramod Khedekar

S. S. Menghani*, Chikhale, R., Pant, A., Bijo Mathew, and Khedekar, P., “Molecular Docking, Synthesis and CNS Activity of Some Novel 1, 4-Benzodiazepine Derivatives”, 2017.

Year : 2017

Structural Exploration of Synthetic Chromones as Selective MAO-B Inhibitors: A Mini Review.

Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Petzer, Jacobus P; Petzer, Anel

Publisher : Comb Chem High Throughput Screen

Bijo Mathew, Mathew, G. Elizabeth, Petzer, J. P., and Petzer, A., “Structural Exploration of Synthetic Chromones as Selective MAO-B Inhibitors: A Mini Review.”, Comb Chem High Throughput Screen, vol. 20, no. 6, pp. 522-532, 2017.

Year : 2017

Refining the Structural Features of Chromones as Selective MAO-B Inhibitors: Exploration of Combined Pharmacophore-Based 3D-QSAR and Quantum Chemical Studies

Authors : Dr. Bijo Mathew, Bijo Mathew; Dev, Sanal; Joy, Monu; Mathew, Githa E.; Marathakam, Akash; Krishnan, Girish K.

Publisher : John Wiley & Sons, Ltd

Bijo Mathew, Dev, S., Joy, M., Mathew, G. E., Marathakam, A., and Krishnan, G. K., “Refining the Structural Features of Chromones as Selective MAO-B Inhibitors: Exploration of Combined Pharmacophore-Based 3D-QSAR and Quantum Chemical Studies”, ChemistrySelectChemistrySelectChemistrySelect, vol. 2, no. 35, pp. 11645 - 11652, 2017.

Year : 2016

Monoamine Oxidase Inhibitory Activity: Methyl- versus Chlorochalcone Derivatives.

Authors : Dr. Bijo Mathew, Bijo Mathew; Ucar, Gülberk; Mathew, Githa Elizabeth; Mathew, Sincy; Kalatharakkal Purapurath, Praseedha; Moolayil, Fasil; Mohan, Smrithy; Varghese Gupta, Sheeba

Publisher : ChemMedChem

Bijo Mathew, Ucar, G., Mathew, G. Elizabeth, Mathew, S., Purapurath, P. Kalatharak, Moolayil, F., Mohan, S., and Gupta, S. Varghese, “Monoamine Oxidase Inhibitory Activity: Methyl- versus Chlorochalcone Derivatives.”, ChemMedChem, vol. 11, no. 24, pp. 2649-2655, 2016.

Year : 2016

Synthesis, Biochemistry, and Computational Studies of Brominated Thienyl Chalcones: A New Class of Reversible MAO-B Inhibitors.

Authors : Dr. Bijo Mathew, Haridas, Abitha; Ucar, Gülberk; Baysal, Ipek; Joy, Monu; Mathew, Githa E; Lakshmanan, Baskar; Jayaprakash, Venkatesan

Publisher : ChemMedChem

Bijo Mathew, Haridas, A., Ucar, G., Baysal, I., Joy, M., Mathew, G. E., Lakshmanan, B., and Jayaprakash, V., “Synthesis, Biochemistry, and Computational Studies of Brominated Thienyl Chalcones: A New Class of Reversible MAO-B Inhibitors.”, ChemMedChem, vol. 11, no. 11, pp. 1161-71, 2016.

Year : 2016

Exploration of chlorinated thienyl chalcones: A new class of monoamine oxidase-B inhibitors.

Authors : Dr. Bijo Mathew, Haridas, Abitha; Ucar, Gülberk; Baysal, Ipek; Adeniyi, Adebayo A; Soliman, Mahmoud E S; Joy, Monu; Mathew, Githa Elizabeth; Lakshmanan, Baskar; Jayaprakash, Venkatesan

Publisher : Int J Biol Macromol

Bijo Mathew, Haridas, A., Ucar, G., Baysal, I., Adeniyi, A. A., Soliman, M. E. S., Joy, M., Mathew, G. Elizabeth, Lakshmanan, B., and Jayaprakash, V., “Exploration of chlorinated thienyl chalcones: A new class of monoamine oxidase-B inhibitors.”, Int J Biol Macromol, vol. 91, pp. 680-95, 2016.

Year : 2016

Ligand based drug design of new heterocyclic imines of GABA analogues: A molecular docking approach for the discovery of new GABA-AT inhibitors.

Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Suresh, Jerad; Usman, Dhasthakeer; Shiva Subramanyan, Puthucode Natarajan; Safna, Kallivalappil Fathima

Publisher : Cent Nerv Syst Agents Med Chem

Bijo Mathew, Mathew, G. Elizabeth, Suresh, J., Usman, D., Subramanyan, P. Natarajan, and Safna, K. Fathima, “Ligand based drug design of new heterocyclic imines of GABA analogues: A molecular docking approach for the discovery of new GABA-AT inhibitors.”, Cent Nerv Syst Agents Med Chem, 2016.

Year : 2016

Identification of Indole-Based Chalcones: Discovery of a Potent, Selective, and Reversible Class of MAO-B Inhibitors.

Authors : Dr. Bijo Mathew, Sasidharan, Rani; Manju, Sreedharannair Leelabaiamma; Ucar, Gülberk; Baysal, Ipek

Publisher : Arch Pharm (Weinheim)

R. Sasidharan, Manju, S. Leelabaiam, Ucar, G., Baysal, I., and Bijo Mathew, “Identification of Indole-Based Chalcones: Discovery of a Potent, Selective, and Reversible Class of MAO-B Inhibitors.”, Arch Pharm (Weinheim), vol. 349, no. 8, pp. 627-37, 2016.

Year : 2016

Discovery of Camptothecin Based Topoisomerase I Inhibitors: Identification Using an Atom Based 3D-QSAR, Pharmacophore Modeling, Virtual Screening and Molecular Docking Approach.

Authors : Dr. Bijo Mathew, Dev, Sanal; Dhaneshwar, Sunil R; Bijo Mathew

Publisher : Comb Chem High Throughput Screen

S. Dev, Dhaneshwar, S. R., and Bijo Mathew, “Discovery of Camptothecin Based Topoisomerase I Inhibitors: Identification Using an Atom Based 3D-QSAR, Pharmacophore Modeling, Virtual Screening and Molecular Docking Approach.”, Comb Chem High Throughput Screen, vol. 19, no. 9, pp. 752-763, 2016.

Year : 2016

Development of novel (1-H) benzimidazole bearing pyrimidine-trione based MAO-A inhibitors: Synthesis, docking studies and antidepressant activity

Authors : Dr. Bijo Mathew, Jerad Suresh; S. Anbazhagan

Publisher : Journal of Saudi Chemical Society

Bijo Mathew, Suresh, J., and Anbazhagan, S., “Development of novel (1-H) benzimidazole bearing pyrimidine-trione based MAO-A inhibitors: Synthesis, docking studies and antidepressant activity”, Journal of Saudi Chemical Society, vol. 20, pp. S132-S139, 2016.

Year : 2016

Discovery of some novel imines of 2-amino, 5-thio, 1,3,4-thiadiazole as mucomembranous protector. Synthesis, anti-oxidant activity and in silico PASS approach

Authors : Dr. Bijo Mathew, Jerad Suresh; S. Anbazhagan; N. Chidambaranathan

Publisher : Journal of Saudi Chemical Society

Bijo Mathew, Suresh, J., Anbazhagan, S., and Chidambaranathan, N., “Discovery of some novel imines of 2-amino, 5-thio, 1,3,4-thiadiazole as mucomembranous protector. Synthesis, anti-oxidant activity and in silico PASS approach”, Journal of Saudi Chemical Society, vol. 20, pp. S426-S432, 2016.

Year : 2016

Potent and Selective Monoamine Oxidase-B Inhibitory Activity: Fluoro- vs. Trifluoromethyl-4-hydroxylated Chalcone Derivatives.

Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Ucar, Gülberk; Baysal, Ipek; Suresh, Jerad; Mathew, Sincy; Haridas, Abitha; Jayaprakash, Venkatesan

Publisher : Chem Biodivers

Bijo Mathew, Mathew, G. Elizabeth, Ucar, G., Baysal, I., Suresh, J., Mathew, S., Haridas, A., and Jayaprakash, V., “Potent and Selective Monoamine Oxidase-B Inhibitory Activity: Fluoro- vs. Trifluoromethyl-4-hydroxylated Chalcone Derivatives.”, Chem Biodivers, vol. 13, no. 8, pp. 1046-52, 2016.

Year : 2016

Monoamine Oxidase Inhibitors: Perspective Design for the Treatment of Depression and Neurological Disorders

Authors : Dr. Bijo Mathew, Githa E. Mathew; Jerad Suresh; Gülberk Ucar; Rani Sasidharan; Sockalingam Anbazhagan; Jobin K. Vilapurathu and Venkatesan Jayaprakash

Bijo Mathew, Mathew, G. E., Suresh, J., Ucar, G., Sasidharan, R., Anbazhagan, S., and Jayaprakash, J. K. Vilapur, “Monoamine Oxidase Inhibitors: Perspective Design for the Treatment of Depression and Neurological Disorders”, 2016.

Year : 2016

Molecular Docking Studies of Some Novel Antidepressant 5-Substituted Phenyl-3-(Thiophen-2-yl)-4, 5-Dihydro-1h-Pyrazole-1-Carboxamides Against Monoamine Oxidase Isoforms.

Authors : Dr. Bijo Mathew, Suresh, Jerad; Anbazhagan, Sockalingam; Dev, Sanal

Publisher : Cent Nerv Syst Agents Med Chem

Bijo Mathew, Suresh, J., Anbazhagan, S., and Dev, S., “Molecular Docking Studies of Some Novel Antidepressant 5-Substituted Phenyl-3-(Thiophen-2-yl)-4, 5-Dihydro-1h-Pyrazole-1-Carboxamides Against Monoamine Oxidase Isoforms.”, Cent Nerv Syst Agents Med Chem, vol. 16, no. 2, pp. 75-80, 2016.

Year : 2016

Monoamine Oxidase Inhibitory Action of Chalcones: A Mini Review.

Authors : Dr. Bijo Mathew, Haridas, Abitha; Suresh, Jerad; Mathew, Githa E; Ucar, Gülberk; Jayaprakash, Venkatesan

Publisher : Cent Nerv Syst Agents Med Chem

Bijo Mathew, Haridas, A., Suresh, J., Mathew, G. E., Ucar, G., and Jayaprakash, V., “Monoamine Oxidase Inhibitory Action of Chalcones: A Mini Review.”, Cent Nerv Syst Agents Med Chem, vol. 16, no. 2, pp. 120-36, 2016.

Year : 2016

Pharmacophore Modeling, 3D-QSAR and Molecular Docking of Furanochalcones as Inhibitors of Monoamine Oxidase-B.

Authors : Dr. Bijo Mathew, Dev, Sanal; Suresh, Jerad; Mathew, Githa E; Lakshmanan, Baskar; Haridas, Abitha; Fathima, Fajeelath; Krishnan, Girish K

Publisher : Cent Nerv Syst Agents Med Chem

Bijo Mathew, Dev, S., Suresh, J., Mathew, G. E., Lakshmanan, B., Haridas, A., Fathima, F., and Krishnan, G. K., “Pharmacophore Modeling, 3D-QSAR and Molecular Docking of Furanochalcones as Inhibitors of Monoamine Oxidase-B.”, Cent Nerv Syst Agents Med Chem, vol. 16, no. 2, pp. 105-11, 2016.

Year : 2016

Synthesis, ADME studies, toxicity estimation, and exploration of molecular recognition of thiophene based chalcones towards monoamine oxidase-A and B

Authors : Dr. Bijo Mathew, Bijo Mathew; Suresh, Jerad; Elizabeth Mathew, Githa; Haridas, Abitha; Suresh, Geethu; Sabreena, P.

Publisher : Volume 5, Issue 4, p.396 - 401 (2016)

Bijo Mathew, Suresh, J., Mathew, G. Elizabeth, Haridas, A., Suresh, G., and Sabreena, P., “Synthesis, ADME studies, toxicity estimation, and exploration of molecular recognition of thiophene based chalcones towards monoamine oxidase-A and B”, vol. 5, no. 4, pp. 396 - 401, 2016.

Year : 2015

Development of Fluorinated Thienylchalcones as Monoamine Oxidase-B Inhibitors: Design, Synthesis, Biological Evaluation and Molecular Docking Studies

Authors : Dr. Bijo Mathew, Gülberk Ucar; Samiye Yabanogclu-Ciftci; Ipek Baysal; Jerad Suresh; Githa Elizabeth Mathew; Jobin Kunjumon Vilapurathu; A. M. Nadeena; P. Nabeela; V. Lakshmi; Abitha Haridas and Fajeelath Fathima

Bijo Mathew, Ucar, G., Yabanogclu-Ciftci, S., Baysal, I., Suresh, J., Mathew, G. Elizabeth, Vilapurathu, J. Kunjumon, Nadeena, A. M., Nabeela, P., Lakshmi, V., and Fathima, A. Haridas an, “Development of Fluorinated Thienylchalcones as Monoamine Oxidase-B Inhibitors: Design, Synthesis, Biological Evaluation and Molecular Docking Studies”, 2015.

Year : 2015

Psychomotor Seizure Screening and in vitro Neuroprotection Assay of Hydrazones Derived from 2-Acetyl Thiophene.

Authors : Dr. Bijo Mathew, Bijo Mathew; Mathew, Githa E; Suresh, Jerad; Jaseel, Mohammed; Usman, D; Shiva Subramanyan, P N; Safna, Kallivalappil F; Vilapurathu, Jobin K

Publisher : Cent Nerv Syst Agents Med Chem

Bijo Mathew, Mathew, G. E., Suresh, J., Jaseel, M., Usman, D., Subramanyan, P. N. Shiva, Safna, K. F., and Vilapurathu, J. K., “Psychomotor Seizure Screening and in vitro Neuroprotection Assay of Hydrazones Derived from 2-Acetyl Thiophene.”, Cent Nerv Syst Agents Med Chem, 2015.

Year : 2015

Determination of in vitro free radical scavenging and antiproliferative effect of Pennisetum alopecuroides on cultured A549 human lung cancer cells.

Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Bijo Mathew; Gokul, S; Krishna, Rahul; Farisa, M P

Publisher : Anc Sci Life

G. Elizabeth Mathew, Bijo Mathew, Gokul, S., Krishna, R., and Farisa, M. P., “Determination of in vitro free radical scavenging and antiproliferative effect of Pennisetum alopecuroides on cultured A549 human lung cancer cells.”, Anc Sci Life, vol. 34, no. 3, pp. 175-8, 2015.

Year : 2015

Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies.

Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Ucar, Gülberk; Baysal, Ipek; Suresh, Jerad; Vilapurathu, Jobin Kunjumon; Prakasan, Aneesh; Suresh, Jeethu Kuruppath; Thomas, Anjana

Publisher : Bioorg Chem

Bijo Mathew, Mathew, G. Elizabeth, Ucar, G., Baysal, I., Suresh, J., Vilapurathu, J. Kunjumon, Prakasan, A., Suresh, J. Kuruppath, and Thomas, A., “Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies.”, Bioorg Chem, vol. 62, pp. 22-9, 2015.

Year : 2015

Flavonoids: An Outstanding Structural Core for the Inhibition of Xanthine Oxidase Enzyme

Authors : Dr. Bijo Mathew, Jerad Suresh; Githa E. Mathew; Sherin A. Rasheed; Jobin K. Vilapurathu and P. Jayaraj

Bijo Mathew, Suresh, J., Mathew, G. E., Rasheed, S. A., and Jayaraj, J. K. Vilapur, “Flavonoids: An Outstanding Structural Core for the Inhibition of Xanthine Oxidase Enzyme”, 2015.

Year : 2015

Molecular Hybridization and Preclinical Evaluation of Imines From Para-substituted 4-phenyl 2-amino Thiazole Incorporated with Isatin Analogues as Antitubercular Agents

Authors : Dr. Bijo Mathew, Nice Joy

Publisher : Anti-Infective Agents

N. Joy and Bijo Mathew, “Molecular Hybridization and Preclinical Evaluation of Imines From Para-substituted 4-phenyl 2-amino Thiazole Incorporated with Isatin Analogues as Antitubercular Agents”, Anti-Infective Agents, 13 vol., no. 1, 2015.

Year : 2015

Hydrazones as a privileged structural linker in antitubercular agents: a review.

Authors : Dr. Bijo Mathew, Suresh, Jerad; Ahsan, Mohamed J; Mathew, Githa E; Usman, Dhasthakeer; Subramanyan, Puthucode N S; Safna, Kallivalappil F; Maddela, Srinubabu

Publisher : Infect Disord Drug Targets

Bijo Mathew, Suresh, J., Ahsan, M. J., Mathew, G. E., Usman, D., Subramanyan, P. N. S., Safna, K. F., and Maddela, S., “Hydrazones as a privileged structural linker in antitubercular agents: a review.”, Infect Disord Drug Targets, vol. 15, no. 2, pp. 76-88, 2015.

Year : 2014

Molecular Recognisation of 3a, 4-Dihydro-3-H-Indeno [1, 2-C] Pyrazole-2- Carboxamide/Carbothioamide Anticonvulsant Analogues Towards GABA-Aminotransferase- An in Silico Approach

Authors : Dr. Bijo Mathew, Ahsan, Mohamed

Publisher : Central Nervous System Agents in Medicinal Chemistry

Bijo Mathew and Ahsan, M., “Molecular Recognisation of 3a, 4-Dihydro-3-H-Indeno [1, 2-C] Pyrazole-2- Carboxamide/Carbothioamide Anticonvulsant Analogues Towards GABA-Aminotransferase- An in Silico Approach”, Central Nervous System Agents in Medicinal Chemistry, vol. 14, 2014.

Year : 2014

Isolation of chemical constituents from Spilanthes calva DC: Toxicity, anthelmintic efficacy and in silico studies

Authors : Dr. Bijo Mathew, P. Jayaraj; C. Mani; R. Govindarajan

Publisher : Biomedicine & Preventive Nutrition

P. Jayaraj, Bijo Mathew, Mani, C., and Govindarajan, R., “Isolation of chemical constituents from Spilanthes calva DC: Toxicity, anthelmintic efficacy and in silico studies”, Biomedicine & Preventive Nutrition, vol. 4, pp. 417-423, 2014.

Year : 2014

Synthesis, preclinical evaluation and antidepressant activity of 5-substituted phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides.

Authors : Dr. Bijo Mathew, Suresh, Jerad; Anbazhagan, S

Publisher : EXCLI J

Bijo Mathew, Suresh, J., and Anbazhagan, S., “Synthesis, preclinical evaluation and antidepressant activity of 5-substituted phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides.”, EXCLI J, vol. 13, pp. 437-45, 2014.

Year : 2014

Design, Synthesis, Toxicity Estimation and Molecular Docking Studies of N-(furan-2-yl)-1-(5-substituted) phenyl-1,3,4-oxadiazol-2-yl) methanimine as Antitubercular Agents.

Authors : Dr. Bijo Mathew, Suresh, J; Mathew, Githa E; Sonia, George; Krishnan, G K

Publisher : Indian J Pharm Sci

Bijo Mathew, Suresh, J., Mathew, G. E., Sonia, G., and Krishnan, G. K., “Design, Synthesis, Toxicity Estimation and Molecular Docking Studies of N-(furan-2-yl)-1-(5-substituted) phenyl-1,3,4-oxadiazol-2-yl) methanimine as Antitubercular Agents.”, Indian J Pharm Sci, vol. 76, no. 5, pp. 401-6, 2014.

Year : 2014

Proposed interaction of some novel antidepressant pyrazolines against monoamine oxidase isoforms. Molecular docking studies and PASS assisted in silico approach

Authors : Dr. Bijo Mathew, Jerad Suresh; S. Anbazhagan; Sanal Dev

Publisher : Biomedicine & Aging Pathology

Bijo Mathew, Suresh, J., Anbazhagan, S., and Dev, S., “Proposed interaction of some novel antidepressant pyrazolines against monoamine oxidase isoforms. Molecular docking studies and PASS assisted in silico approach”, Biomedicine & Aging Pathology, vol. 4, pp. 297-301, 2014.

Year : 2014

Plant secondary metabolites- potent inhibitors of monoamine oxidase isoforms.

Authors : Dr. Bijo Mathew, Bijo Mathew; Suresh, Jerad; Mathew, Githa E; Parasuraman, Ramamoorthy; Abdulla, Nalakathu

Publisher : Cent Nerv Syst Agents Med Chem

Bijo Mathew, Suresh, J., Mathew, G. E., Parasuraman, R., and Abdulla, N., “Plant secondary metabolites- potent inhibitors of monoamine oxidase isoforms.”, Cent Nerv Syst Agents Med Chem, vol. 14, no. 1, pp. 28-33, 2014.

Year : 2014

Isolation and molecular recognization of 6-prenyl apigenin towards MAO-A as the active principle of seeds of Achyranthes aspera

Authors : Dr. Bijo Mathew, Shoban Janet Beula; V. Bhaskar Anada Raj

Publisher : Biomedicine & Preventive Nutrition

S. Janet Beula, V. Raj, B. Anada, and Bijo Mathew, “Isolation and molecular recognization of 6-prenyl apigenin towards MAO-A as the active principle of seeds of Achyranthes aspera”, Biomedicine & Preventive Nutrition, vol. 4, pp. 379-382, 2014.

Year : 2014

Synthesis, in silico preclinical evaluation, antidepressant potential of 5-substituted phenyl-3-(thiophen-2-yl)-4,5-dihydro-1h-pyrazole-1-carboxamides

Authors : Dr. Bijo Mathew, Jerad Suresh; S. Anbazhagan

Publisher : Biomedicine & Aging Pathology

Bijo Mathew, Suresh, J., and Anbazhagan, S., “Synthesis, in silico preclinical evaluation, antidepressant potential of 5-substituted phenyl-3-(thiophen-2-yl)-4,5-dihydro-1h-pyrazole-1-carboxamides”, Biomedicine & Aging Pathology, vol. 4, pp. 327-333, 2014.

Year : 2014

Isolation of a bioactive flavonoid from Spilanthes calva D.C. in vitro xanthine oxidase assay and in silico study

Authors : Dr. Bijo Mathew, P. Jayaraj; Bijo Mathew; B. Parimaladevi; V. Alex Ramani; R. Govindarajan

Publisher : Biomedicine & Preventive Nutrition

P. Jayaraj, Bijo Mathew, Parimaladevi, B., V. Ramani, A., and Govindarajan, R., “Isolation of a bioactive flavonoid from Spilanthes calva D.C. in vitro xanthine oxidase assay and in silico study”, Biomedicine & Preventive Nutrition, vol. 4, pp. 481-484, 2014.

Year : 2014

Heteroaryl chalcones: Mini review about their therapeutic voyage

Authors : Dr. Bijo Mathew, Jerad Suresh; Sockalingam Anbazghagan; Jayaraj Paulraj; Girish K. Krishnan

Publisher : Biomedicine & Preventive Nutrition

Bijo Mathew, Suresh, J., Anbazghagan, S., Paulraj, J., and Krishnan, G. K., “Heteroaryl chalcones: Mini review about their therapeutic voyage”, Biomedicine & Preventive Nutrition, vol. 4, pp. 451-458, 2014.

Year : 2013

Synthesis and in silico design of some novel imines of 5- amino-1,3,4-thiadiazole-2-thiol linked to (1h-benzimidazole-2-yl) 3-substituted phenyl prop-2-enes

Authors : Dr. Bijo Mathew, Suresh, J., and Anbazhagan, S.

Publisher : Indian. J. Heterocycl. Chem

Bijo Mathew, Suresh, J., and Anbazhagan, S., “Synthesis and in silico design of some novel imines of 5- amino-1,3,4-thiadiazole-2-thiol linked to (1h-benzimidazole-2-yl) 3-substituted phenyl prop-2-enes”, Indian. J. Heterocycl. Chem, vol. 22, pp. 337-340, 2013.

Year : 2013

Pyrazoline: a promising scaffold for the inhibition of monoamine oxidase.

Authors : Dr. Bijo Mathew, Suresh, Jerad; Anbazhagan, Sockalingam; Mathew, Githa Elizabeth

Publisher : Cent Nerv Syst Agents Med Chem

Bijo Mathew, Suresh, J., Anbazhagan, S., and Mathew, G. Elizabeth, “Pyrazoline: a promising scaffold for the inhibition of monoamine oxidase.”, Cent Nerv Syst Agents Med Chem, vol. 13, no. 3, pp. 195-206, 2013.

Year : 2013

Antitumour activity of 5-[(2E)-1-(1H-benzimidazol-2-yl)-3-substituted phenylprop-2-en-1-ylidene] pyrimidine-2,4,6(1H,3H,5H)-triones against Dalton’s ascitic lymphoma in mice

Authors : Dr. Bijo Mathew, Suresh, Jerad; Vinod, Devaraji

Publisher : Medicinal Chemistry Research

Bijo Mathew, Suresh, J., and Vinod, D., “Antitumour activity of 5-[(2E)-1-(1H-benzimidazol-2-yl)-3-substituted phenylprop-2-en-1-ylidene] pyrimidine-2,4,6(1H,3H,5H)-triones against Dalton’s ascitic lymphoma in mice”, Medicinal Chemistry Research, vol. 22, no. 8, pp. 3911 - 3917, 2013.

Year : 2013

Design of 1-(furan-2-yl)-N-(5-substituted phenyl-1, 3, 4-thiadiazol-2-yl) methanimine derivatives as Enoyl-ACP reductase inhibitors: Synthesis, molecular docking studies and anti-tubercular activity

Authors : Dr. Bijo Mathew, Mathew, Githa; Sonia, George; Kumar, Anila; Charles, Neethu; Kumar, Palanisamy

Publisher : Bangladesh Journal of Pharmacology

Bijo Mathew, Mathew, G., Sonia, G., Kumar, A., Charles, N., and Kumar, P., “Design of 1-(furan-2-yl)-N-(5-substituted phenyl-1, 3, 4-thiadiazol-2-yl) methanimine derivatives as Enoyl-ACP reductase inhibitors: Synthesis, molecular docking studies and anti-tubercular activity”, Bangladesh Journal of Pharmacology, vol. 8, 2013.

Year : 2013

Hypnotic profile of imines from benzimidazole chalcones: mechanism of synthesis, DFT studies and in silico screening.

Authors : Dr. Bijo Mathew, Suresh, Jerad; Anbazhagan, Sockalingam; Devaraji, Vinod

Publisher : Cent Nerv Syst Agents Med Chem

Bijo Mathew, Suresh, J., Anbazhagan, S., and Devaraji, V., “Hypnotic profile of imines from benzimidazole chalcones: mechanism of synthesis, DFT studies and in silico screening.”, Cent Nerv Syst Agents Med Chem, vol. 13, no. 3, pp. 207-16, 2013.

Year : 2013

Synthesis and PASS-assisted in silico approach of some novel 2-substituted benzimidazole bearing a pyrimidine-2, 4, 6(trione) system as mucomembranous protector.

Authors : Dr. Bijo Mathew, Suresh, Jerad; Anbazhagan, Socklingam

Publisher : J Pharm Bioallied Sci

Bijo Mathew, Suresh, J., and Anbazhagan, S., “Synthesis and PASS-assisted in silico approach of some novel 2-substituted benzimidazole bearing a pyrimidine-2, 4, 6(trione) system as mucomembranous protector.”, J Pharm Bioallied Sci, vol. 5, no. 1, pp. 39-43, 2013.

Year : 2012

A Green route approach of α, β unsaturated ketone having a benzimidazole tail and their virtual screening on the molecular descriptors for predicting the CNS-drug likeness

Authors : Dr. Bijo Mathew, Bijo Mathew; Githa Elizebeth Mathew; Shafeer V.P.,; Mohammed Musthafa C.; Femina P.

Publisher : Asian J. Research Chem

Bijo Mathew, Mathew, G. Elizebeth, ,, C., M. Musthafa, and P., F., “A Green route approach of α, β unsaturated ketone having a benzimidazole tail and their virtual screening on the molecular descriptors for predicting the CNS-drug likeness”, Asian J. Research Chem., vol. 5, no. 1, pp. 65-68, 2012.

Year : 2012

Isolation, in silico design and anti-inflammatory activity of spirosolenol from the roots of Solanum anguvi

Authors : Dr. Bijo Mathew, Mathew, G.E.; George, S.; Shamnas, M.; Raj, V.B.A.

Publisher : Chemical Sciences Journal

Bijo Mathew, Mathew, G. E., George, S., Shamnas, M., and Raj, V. B. A., “Isolation, in silico design and anti-inflammatory activity of spirosolenol from the roots of Solanum anguvi”, Chemical Sciences Journal, 2012.

Year : 2012

Microwave Assisted Synthesis, Physico-chemical Properties and Antioxidant Activity of alpha,beta-Unsaturated Benzimidazole Derivatives Incorporated with Baritone Moiety

Authors : Dr. Bijo Mathew, Suresh, Jerad; Anbazhagan, Sockalingam

Publisher : ASIAN JOURNAL OF CHEMISTRY,

Bijo Mathew, Suresh, J., and Anbazhagan, S., “Microwave Assisted Synthesis, Physico-chemical Properties and Antioxidant Activity of alpha,beta-Unsaturated Benzimidazole Derivatives Incorporated with Baritone Moiety”, ASIAN JOURNAL OF CHEMISTRY, vol. 25, pp. 1853-1856, 2012.

Year : 2011

Synthesis of some thiazolidinone derivatives from indole-2 carboxylic acid and evaluation of its xanthine oxidase inhibitory and antioxidant activity

Authors : Dr. Bijo Mathew, Bhuvna C; Mathew B.; Mahalakshmi A.; Sukumar M.

Publisher : International Journal of ChemTech Research

B. C, B., M., A., M., and M., S., “Synthesis of some thiazolidinone derivatives from indole-2 carboxylic acid and evaluation of its xanthine oxidase inhibitory and antioxidant activity”, International Journal of ChemTech Research, vol. 3, no. 2, pp. 671-675, 2011.

Year : 2011

Diuretic activity of leaves of garcinia cambogia in rats.

Authors : Dr. Bijo Mathew, Mathew, Githa E; Shaneeb, M M; Nyanthara, B

Publisher : Indian J Pharm Sci

G. E. Mathew, Bijo Mathew, Shaneeb, M. M., and Nyanthara, B., “Diuretic activity of leaves of garcinia cambogia in rats.”, Indian J Pharm Sci, vol. 73, no. 2, pp. 228-30, 2011.

Year : 2011

Phytochemical evaluation and lipid lowering property of leaves of Vitex negun- do linn. in hyper cholestremic rats

Authors : Dr. Bijo Mathew, Githa, Elizabeth, Mathew

Publisher : IJPSRR

E. Githa, Mathew,, and Bijo Mathew, “Phytochemical evaluation and lipid lowering property of leaves of Vitex negun- do linn. in hyper cholestremic rats”, IJPSRR, vol. 2, 2011.

Year : 2011

Synthesis, characterization and antimicrobial screening of some 2-amino, 5(phenyl substituted) 1, 3, 4-thiadiazole derivatives

Authors : Dr. Bijo Mathew, AJ, J., GE, M., S, S., and SS, K.

Publisher : International Journal of ChemTech Research

Bijo Mathew, AJ, J., GE, M., S, S., and SS, K., “Synthesis, characterization and antimicrobial screening of some 2-amino, 5(phenyl substituted) 1, 3, 4-thiadiazole derivatives”, International Journal of ChemTech Research, vol. 1, no. 3, pp. 364-368, 2011.

Year : 2011

Anthelmintic activity of leaves of garcinia cambogia

Authors : Dr. Bijo Mathew, Mathew, G.E.; Sheneeb, M.; Nyanthara, N.; Haribabu, Y.

Publisher : International Journal of Research in Pharmaceutical Sciences

G. E. Mathew, Bijo Mathew, Sheneeb, M., Nyanthara, N., and Haribabu, Y., “Anthelmintic activity of leaves of garcinia cambogia”, International Journal of Research in Pharmaceutical Sciences, vol. 2, pp. 63-65, 2011.

Year : 2010

Synthesis, molecular properties and anthelmintic activity of some schiff bases of 1, 3, 4 thiadiazole derivatives

Authors : Dr. Bijo Mathew, Vakketh, S.S.; Kumar, S.S.

Publisher : Der pharma chemica

B. Mathew, Vakketh, S. S., and Kumar, S. S., “Synthesis, molecular properties and anthelmintic activity of some schiff bases of 1, 3, 4 thiadiazole derivatives”, Der pharma chemica, vol. 2, pp. 337-343, 2010.

Year : 2010

Synthesis, Characterisation of some 2-azetidinone derivatives from 2-aminopyridine and evaluation of their antimicrobial activity

Authors : Dr. Bijo Mathew, Githa Elizebeth Mathew; Nirmal Mathew; M. Vijayabaskaran

Publisher : Der Pharma Chemica

Bijo Mathew, Mathew, G. Elizebeth, Mathew, N., and Vijayabaskaran, M., “Synthesis, Characterisation of some 2-azetidinone derivatives from 2-aminopyridine and evaluation of their antimicrobial activity”, Der Pharma Chemica, vol. 2, no. 6, pp. 238-242, 2010.

Year : 2010

Phytochemical evaluation and anticancer screening of rhizomes of Kaempferia galanga

Authors : Dr. Bijo Mathew, M, V., GE, M., and KM, T.

Publisher : InternationalResearch Journal of Pharmaceutical Sciences

Bijo Mathew, M, V., GE, M., and KM, T., “Phytochemical evaluation and anticancer screening of rhizomes of Kaempferia galanga”, InternationalResearch Journal of Pharmaceutical Sciences, vol. 1, no. 1, pp. 11-15, 2010.

Book Chapter

Year : 2021

Protopine, Naturally Occurring Chemicals Against Alzheimer’s Disease

Authors : Dr. Bijo Mathew, Parambi D.G.T., Singh M., Hendawy O.M., and Al-Sanea M.M. Bakr R.B.

Publisher : Academic Press [Elsevier Publication]

Bijo Mathew, Parambi D.G.T., Singh M., Hendawy O.M., and Al-Sanea M.M. Bakr R.B., “Protopine, Naturally Occurring Chemicals Against Alzheimer's Disease”, Academic Press [Elsevier Publication], 2021, pp. 167-174.

Year : 2020

Demographic and Epidemiological Aspects of Aging

Authors : Dr. Bijo Mathew, Parambi D.G.T.; Unnikrishnan M.K.; Marathakam A.

Publisher : Nabavi S.M., D'Onofrio G., Nabavi S.F. (eds) Nutrients and Nutraceuticals for Active & Healthy Ageing, Springer Singapore, Singapore

Parambi D.G.T., Unnikrishnan M.K., Marathakam A., and Bijo Mathew, “Demographic and Epidemiological Aspects of Aging”, in In: Nabavi S.M., D'Onofrio G., Nabavi S.F. (eds) Nutrients and Nutraceuticals for Active & Healthy Ageing, Singapore: Springer Singapore, 2020, pp. 1 - 14.

Year : 2020

Epidermal Growth Factor Receptor (EGFR): Promising targets for Non-Small Cell Lung Cancer

Authors : Dr. Bijo Mathew, P. DGT, KM, N., MS, U.

Publisher : Springer Publishers

P. DGT, KM, N., MS, U., and Bijo Mathew, “Epidermal Growth Factor Receptor (EGFR): Promising targets for Non-Small Cell Lung Cancer”, Springer Publishers, 2020, pp. 465-471.

Year : 2020

Neurochemicals in Nervous System and Exploring the Chemical Make-Up of Human Brain

Authors : Dr. Bijo Mathew, Harilal, Seetha; Kumar, Rajesh; Mathew, Githa Elizabeth; Jose, Jobin; Uddin, Md. Sahab

Publisher : Springer Singapore, Singapore

S. Harilal, Kumar, R., Mathew, G. Elizabeth, Jose, J., Uddin, M. Sahab, and Bijo Mathew, “Neurochemicals in Nervous System and Exploring the Chemical Make-Up of Human Brain”, in Principles of Neurochemistry: Fundamentals and Applications, B. Mathew and Parambi, D. Grace Thom, Eds. Singapore: Springer Singapore, 2020, pp. 19 - 39.

Year : 2020

Epidermal Growth Factor Receptor (EGFR): Promising targets for Non-Small Cell Lung Cance

Authors : Dr. Bijo Mathew, P. DGT, KM, N., MS, U.

Publisher : Springer Publishers

P. DGT, KM, N., MS, U., and Bijo Mathew, “Epidermal Growth Factor Receptor (EGFR): Promising targets for Non-Small Cell Lung Cancer”, Springer Publishers, 2020, pp. 465-471.

Year : 2020

Neurochemicals in Nervous System and Exploring the Chemical Make-Up of Human Brain

Authors : Dr. Bijo Mathew, Harilal, Seetha; Kumar, Rajesh; Mathew, Githa Elizabeth; Jose, Jobin; Uddin, Md. Sahab

Publisher : Principles of Neurochemistry: Fundamentals and Applications

S. Harilal, Kumar, R., Mathew, G. Elizabeth, Jose, J., Uddin, M. Sahab, and Bijo Mathew, “Neurochemicals in Nervous System and Exploring the Chemical Make-Up of Human Brain”, in Principles of Neurochemistry: Fundamentals and Applications, B. Mathew and Parambi, D. Grace Thom, Eds. Singapore: Springer Singapore, 2020, pp. 19 - 39.

Year : 2017

The Search for Novel Antidepressants: An Integrative View to Drug Discovery- Chapter-5- Monoamine Oxidase-A: A Valid Target for the Management of Depression

Authors : Dr. Bijo Mathew, Suresh, J.

Publisher : BenthamScience Publisher

Bijo Mathew and Suresh, J., “The Search for Novel Antidepressants: An Integrative View to Drug Discovery- Chapter-5- Monoamine Oxidase-A: A Valid Target for the Management of Depression”, vol. 2, BenthamScience Publisher, 2017, pp. 132-140.

Patents

Year : 2020

Protective or therapeutic compositions of neurological disorders containing furano chalcones as effective agents

Authors : Dr. Bijo Mathew, Suresh J., Baek S. C., Ramakrishnan S.P., Kim H.

S. J., C., B. S., S.P., R., H., K., and Bijo Mathew, “Protective or therapeutic compositions of neurological disorders containing furano chalcones as effective agents”, 2020.

Year : 2020

Composition for preventing or treating ethyl acetohydroxmate incorporated chalcones as an active ingredient

Authors : Dr. Bijo Mathew, Kim H., Baek S.C., Lee J. P., Bijo Mathew, Rangarajan TM, and Reeta

Publisher : Patent file no:10-2020-0054743 [Korean Intellectual Property of Office (KIPO)]

K. H., S.C., B., P., L. J., Bijo Mathew, TM, R., and Reeta, “Composition for preventing or treating ethyl acetohydroxmate incorporated chalcones as an active ingredient”, 2020.

Book

Year : 2021

Medicinal Chemistry –II

Authors : Dr. Bijo Mathew, Dr. Manjinder Singh;

Publisher : Doonville Publishers (P) Ltd

D. Manjinder Singh and Bijo Mathew, Medicinal Chemistry –II. eReadOn (Doonville Publishers (P) Ltd), 2021.

Year : 2020

Principles of Neurochemistry Fundamentals and Applications

Authors : Dr. Bijo Mathew, Parambi, Della

Bijo Mathew and Parambi, D., Principles of Neurochemistry Fundamentals and Applications. 2020.

Teaching Experience
Year Affiliation
Present Associate Professor, Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Kochi, India.
November 11, 2015 – October 31, 2020 Associate Professor, Ahalia School of Pharmacy, Palakkad, India.
Subjects Taught:
– Pharmaceutical Organic Chemistry (B. Pharm.)
– Medicinal Chemistry (B. Pharm.)
November 23, 2009 – October 31, 2015 Assistant Professor, Grace College of Pharmacy, Palakkad, India.
Subjects Taught:
– Pharmaceutical Organic Chemistry (B. Pharm.)
– Medicinal Chemistry (B. Pharm.)
– Advanced Medicinal Chemistry (M. Pharm.)
August 18, 2008 – July 29, 2009 Lecturer, Nehru College of Pharmacy, Thrissur, India.
Subjects Taught:
– Pharmaceutical Organic Chemistry
– Medicinal Chemistry
Workshops and Trainings Attended
No. Area Venue Duration
1. Computer-aided drug design seminar and hands-on training of GLIDE software College of Pharmacy, Madras Medical College, Chennai, India. January 4-5, 2011
2. Course Work on “Research Methodology  J.N.T.U. Hyderabad, India. June 6-11, 2011
3. National  workshop on NMR spectroscopy: Theory, Principle and instrumentation  IIRBS Mahatma Gandhi University, Kottayam, India. September 10-13, 2014
4. Role of Indian Regulators and Pharma Industry 66th Indian Pharmaceutical Congress-Hyderabad, India. January 23-25-, 2015
Invited Talks
International Level
No. Topic Year and Venue
1. Chalcone chemistry towards monoamine oxidase enzyme inhibition: Development of new class of Anti-Alzheimer’s agents July 1, 2019 – International Multidisciplinary Symposium on Drug Research and Development-Inonu University-Malatya-Turkey
National Level
No. Topic Year and Venue
1. Extraction of Phytochemicals and their Importance 2009 – Nehru College of Pharmacy, Thrissur, Kerala, India.
2. Utilization of Open-source Software for the Drug Discovery Process 2013 – College of Pharmacy, Madras Medical College, Chennai, India.
3. Utilization of Computational Tools in Drug Discovery August 24, 2013 – Jamia Salifia Pharmacy College, Pulikal, Kerala, India.
4. Drug Receptor Interaction and Hands-on Training of AutoDock4.2. and its Interpretation January 31, 2014 – College of Pharmacy, Madras Medical College, Chennai, India.
5. Workshop on Docking Studies of Synthetic Molecules April 3, 2014 – Devaki Amma Memorial College of Pharmacy, Malappuram, Kerala, India.
6. Basic Principles of Drug Design and QSAR Approach April 28, 2015 – Moulana College of Pharmacy, Perinthelmanna, Kerala, India.
7. Rational Approaches of Drug Design and Introduction of CADD February 20, 2016 – Malik Deenar College of Pharmacy, Kasaragod, Kerala, India.
8. Workshop on the Design and Docking Studies of MAO Inhibitors (AutoDock Tools) June 25, 2016 – College of Pharmacy, Madras Medical College, Chennai, India.
9. Introduction to Drug Design and Drug Development October 19, 2016  – National College of Pharmacy, Calicut, Kerala, India.
10. Integrated View of Structure-based Drug Design of Newer Molecules November 18, 2016 – Karpagam University, Coimbatore, India.
11. Principles of Drug Design and Introduction of CADD November 25, 2017 – Srikrishna College of Pharmacy, Trivandrum
12. Relevance of Molecular Docking in Drug Design December 17, 2017 – National College of Pharmacy, Calicut, Kerala, India.
13. Workshop on the Docking Studies of MAO-B Inhibitors (AutoDock Tools) January 20, 2018 – National College of Pharmacy, Calicut, Kerala, India.
14. Seminar cum Workshop on the Docking Studies of (AutoDock Tools) February 24, 2018 – KVM College of Pharmacy, Cherthala, Kerala, India.
15. Seminar cum Workshop on the Docking Studies of (AutoDock Tools) February 22, 2019 – Devaki Amma Memorial College of Pharmacy, Malappuram, Kerala, India.
16. An Overview on Molecular Docking and QSAR Febraury 23, 2019 – Swamy Vivekanda College of Pharmacy, Tamilnadu, India.
17. Introduction of Drug Design and Protein Target Prediction October 19, 2019 – College of Pharmacy, Madras Medical College, Chennai, India.
18. Seminar cum Workshop on AutoDock based Drug Design October 26, 2019 – Nirmala College of Pharmacy, Muvatupuzha, Kerala India.
19. Perspectives of Drug Design Project in an Academic Scenario: Where We Stand Now & What We Can Do? November 2, 2019 – National College of Pharmacy, Calicut, Kerala, India.
20. Ligand-based Drug Design Special Emphasis with 2D and 3D QSAR December 10, 2019 – Thanthai Rover college of Pharmacy, Perambalur, Tamilnadu, India.
21. Research Methodology: A Process from Literature Review to Thesis Writing January 18, 2020 – National College of Pharmacy, Calicut, Kerala, India
22. Drug Design Principles and Molecular Docking Techniques June 5, 2020 – Vinayaka Mission’s College of Pharmacy, Salem, Tamilnadu, India.
23. Drug Reposition: Transformation on Hard Work to Mart Work August 22, 2020 – Nirmala College of Pharmacy, Muvatupuzha, Kerala India.
24. Over-view of drug receptor interactions 31-5-2021 & National Webinar organised by Dr. M.G.R. Educational and Research Institute , Chennai, India.
25. Research Methodology 11-06-2021 & the National Webinar organised by Vinayaka Mission’s University, Salem, India.
26. Writing techniques of a medicinal chemistry research paper in a peer-reviewed journal 31-05-2021 & the National FDP AICTE Sponsored Program organised by National College of Pharmacy, Calicut, India.
International and National Collaborative Research Program Carried out
  1. National Institute of Neurological Disorders and Syndrome (NINDS), National Institute ofHealth (NIH), Bethesda, MD 20892-9020, USA.
  2. Department of Biochemistry, Faculty of Pharmacy, Hacettepe University, Sýhhiye 06100, Ankara, Turkey. (WithProf. Dr. G. Uçar).
  3. Department of pharmacy and research institute of life Pharmaceutical Sciences, Sunchon National University, Suncheon 579922, Republic of Korea (Prof. Dr. Hoon Kim)
  4. Laboratory of Molecular & Cellular Biology, Department of Biological Chemistry-IQUIBICEN, Natural Exact Sciences School, University City,University of Buenos Aires, Buenos Aires (C1428EGA),Argentina. (WithProf. Dr. M. D. Galigniana).
  5. School of Health Sciences, University of KwaZulu-Natal, Westville, Durban 4001, South Africa.(WithProf. Dr. M. E. S. Soliman).
  6. Department of Pharmaceutical Chemistry and Centre of Excellence for Pharmaceutical Sciences, School of Pharmacy, North-West University, Private Bag X6001,Potchefstroom 2520,South Africa.(WithProf. Dr. J.P. Petzer).
  7. Universidade Federal Rural do Rio de Janeiro, Departmento de Quimica. Brazil
  8. Department of Pharmacy, “G. d’Annunzio” University of Chieti-Pescara, via dei Vestini 31, 66100 Chieti, Italy (WithProf. Dr. S. Carradori).
Professional Recognition as an Examiner for Ph.D. & P.G.
  1. “Design, Synthesis and evaluation of new chemical scaffolds as potential anti-cancer agents” by Ms. M. Bhagyalalitha2019 (External Expert in Ph.D.). JSS Academy of Higher Education and Research(Deemed to be University). Mysuru, India.
  2. Doctor of Philosophy Thesis evaluator2017. (International Evaluator) of‘The dual role of cathepsin-d in breast cancer and hiv neuropathogenesis’by O.A. Arodola (Reg No:213569288) under the supervision of Prof. M.E.S. Soliman [School of Health Sciences, University of KwaZulu-Natal, Westville, Durban 4001, South Africa.]
  3. Doctor of Philosophy Thesis evaluator2017. (International Evaluator) of‘Application of advanced computational tools towards the understanding of TB targets and design of potential drug candidates’by Kgothatso E. Machaba (Reg No:215082344) under the supervision of Prof. M.E.S. Soliman [School of Health Sciences, University of KwaZulu-Natal, Westville, Durban 4001, South Africa.]
  4. Post Graduate Thesis evaluator2017. (International Evaluator) of‘Designing of novel HIV/TB Inhibitors Using In silico Drug Design Approaches’ by Lauren Blake (Reg No: 21357002) under the supervision of Prof. M.E.S. Soliman [School of Health Sciences, University of KwaZulu-Natal, Westville, Durban 4001, South Africa.]
Research Fund of Sponsored Projects

International Level Minor

  • Design of new class of halogenated cinnamoyl derivatives as selective monoamine oxidase –B inhibitors by similarity based drug design. [International consultant] Deanship of scientific research (DSR), King Khalid University, Abha, Kingdom of Saudi Arabia. 20000 S.R. [2020]. Project No: 23/1441. Completed.
  • Design, synthesis of Sulphur and nitrogen containing α-β- unsaturated ketones as a new multitarget ligands for the treatment of Alzheimer’s disease.’ [Co-Investigator] Deanship of scientific research (DSR), King Khalid University, Abha, Kingdom of Saudi Arabia. 20000 S.R. [2021]. Project No: 159/42. Ongoing.

National Level Minor

  • Development of Multi-conjugated ketones as the development of new class of dual acting MAO/AChE inhibitors for the treatment of Alzheimer’s disease. [Principal Investigator] [Amrita Vishwa Vidyapeetham, Kochi, India, Seed Grant- 5 Lakhs [2020]. Grant Number K‐PHAR‐20‐628]. Ongoing.
  • Development and fine-tuning of methoxylated α,β-unsaturated ketones as monoamine oxidase inhibitors. Synthesis, biochemistry and computational study. [Principal Investigator] [Kerala State Council for Science, Technology & Environment – 10000 Rs. [2016].File No: 1/SPS-59/2016/CSTE. Completed.
  • Synthesis, in silico design and anticonvulsant screening of some novel thiophene based hydrazone derivatives. [Principal Investigator] [Kerala State Council for Science, Technology & Environment – 10000 Rs. [2014].File No: 77/SPS-52/2014/CSTE. Completed.
  • Development of some new trans-1, 3- substituted diphenyl-2-propen-1-ones as Monoamine Oxidases Inhibitors: An in vitro and in vivo study. [Co- Investigator] [Kerala State Council for Science, Technology & Environment – 10000 Rs. [2015].File No: 01/SPS-54/2015/CSTE. Completed.
Honorarium Received

Honorarium Received

  • Received 400 US dollars in connection with the Guest Editor of the journal ofCentral Nervous System Agents in Medicinal Chemistry [BenthamScience]. Cheque no: 179832121 (Dated 2016 July 31).
  • Received 600 US dollars in connection with the Guest Editor of the journal of Combinatorial Chemistry and High throughput Screening [Bentham Science]. Cheque no: 179832121 (Dated 2021 February 16).

Awards Received

  • Amrita Innovation and Research Awards: [2021] Received Chancellor’s Publication Award
  • Amrita Innovation and Research Awards: [2021] Received Publication Merit award.
  • Received Best Resource Person award in 2021 at National College of Pharmacy in AICTE and learning (ATAL) academy sponsored FDP program

Research Publication

  • Scopus ID: 3700005470
  • Researcher ID is: G-7477-2014
  • Scopus citation: 2128
  • H-index: 29 [Scopus]
  • Google scholar citation: 2517
  • H-index: 31 [Google scholar]
  • i10-index: 74 [Google scholar]
Cumulative Impact Factor: 434.38 [Based on 2021 JCR reports]
NO Journal Title Publisher Impact factor No. of papers
1 Science of the Total Environment Elsevier 7.96 2
2 Current Neuropharmacology Bentham 7.36 1
3 International Journal of Biological Macromolecules Elsevier 6.95 3
4 Oxidative Medicine and Cellular Longevity Hindawi 6.54 2
5 Biomedicine and Pharmacotherapy Elsevier 6.52 1
6 European Journal of Medicinal Chemistry Elsevier 6.51 3
7 Pharmaceutics MDPI 6.30 1
8 Journal of Molecular liquids Elsevier 6.16 2
9 International Journal of Molecular Science MDPI 5.92 1
10 Pharmaceuticals MDPI 5.86 2
11 Molecular Neurobiology Springer 5.50 3
12 Bioorganic Chemistry Elsevier 5.27 2
13 Neural Regeneration Research Medknow 5.13 1
14 Journal of Enzyme Inhibition and Medicinal Chemistry Tailor and Francis 5.05 2
15 Life Science Elsevier 5.03 1
16 Current Medicinal Chemistry Bentham 4.53 3
17 Molecules MDPI 4.41 4
18 CNS and Neurological Disorders and Drug Targets Bentham 4.40 2
19 Environmental Science and Pollution Research Springer 4.22 6
20 Drug Design Development Therapy Dove Press 4.16 1
21 Brain Research Bulletin Elsevier 4.07 1
22 Excli Journal University of Mainz 4.06 1
23 Neurochemical Research Springer 3.99 1
24 Journal of Saudi Chemical Society Elsevier 3.93 2
25 Neurotoxicity Research Springer 3.91 1
26 ACS Combinatorial Science ACS 3.78 1
27 Journal of Pharmacy and Pharmacology Wiley 3.76 3
28 Process  Biochemistry Elsevier 3.76 1
29 Archiv de Pharmazie Wiley 3.75 4
30 MedChemCommun [RSC Medicinal Chemistry] RSC 3.59 1
31 Journal of Biomaterial Research Part A Wiley 3.52 1
32 ACS OMEGA ACS 3.51 1
33 Current Drug Targets Bentham 3.46 3
34 ChemMedChem Wiley 3.46 4
35 Current Topics in Medicinal Chemistry Bentham 3.29 2
36 Current Protein and Peptide Science Bentham 3.27 1
37 IUMB life Wiley 3.24 1
38 Journal of Molecular Structure Elsevier 3.19 4
39 Journal of Neurological Sciences Elsevier 3.18 1
40 Current Pharmaceutical Design Bentham 3.11 7
41 Journal of Physical Chemistry B ACS 2.99 1
42 Chemical Biology and Drug Design Wiley 2.81 1
43 Immunopharmacology and  Immunotoxicology Tailor and Francis 2.73 1
44 Applied Sciences MDPI 2.67 1
45 Evidence based Complementary and Alternative Medicine Hindawi 2.62 1
46 Mini Reviews in Organic Chemistry Bentham 2.49 1
47 Chemistry and Biodiversity Wiley 2.40 1
48 ChemistrySelect Wiley 2.10 7
49 Medicinal Chemistry Research Springer 1.96 1
50 Combinatorial Chemistry and High Throughput Screening Bentham 1.33 8
51 Acta Crystallographica Section C Wiley 1.17 1
52 Letters in Drug Design and Discovery Bentham 1.15 3
53 Indian Journal of Pharmaceutical Sciences MedKnow 0.97 2
54 Bangladesh Journal of Pharmacology BPS 0.93 1
55 Letters in Organic Chemistry Bentham 0.86 1
56 Indian Journal of Heterocyclic Chemistry NACB-India 0.34 1
Category Number of Papers Published
First Author cum Corresponding Author: 58
Corresponding Author 117
Co-Author 40
Single-Author: 2
Total 157
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