Year : 2021
Replacement of chalcone-ethers with chalcone-thioethers as potent and highly selective monoamine oxidase-b inhibitors and their protein-ligand interactions
Authors : Dr. Bijo Mathew, Jong Min Oh, Ahmed Khames, Mohamed A Abdelgawad, T M Rangarajan, Lekshmi R Nath, Clement Agoni, Mahmoud E S Soliman, Githa Elizabeth Mathew, Hoon Kim
Publisher : Pharmaceuticals
Mathew, B., Oh, J.M., Khames, A., Mathew, G.E., Kim, H. Replacement of chalcone-ethers with chalcone-thioethers as potent and highly selective monoamine oxidase-b inhibitors and their protein-ligand interactions, Pharmaceuticals, 2021, 14(11),1148, DOI: 10.3390/ph14111148
Year : 2021
SAR Analysis of Various Heterocyclic Compounds in Medicinal Chemistry: Recent Updates-Part-I
Authors : Dr. Bijo Mathew
Publisher : Current Topics in Medicinal Chemistry
Mathew, B., SAR Analysis of Various Heterocyclic Compounds in Medicinal Chemistry: Recent Updates-Part-I, Current Topics in Medicinal Chemistry, 2021, 21(30), pp. 2694, doi: 10.2174/156802662130211210151841.
Year : 2021
Synthesis of new 1-aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone oxime ether derivatives and investigation of their cytotoxic effects
Authors : Dr. Bijo Mathew, Mehmet Abdullah Alagöz, Arzu Karakurt, Ceylan Hepokur, Emine Şalva, Tijen Önkol, Mohammed M. Ghoneim, Mohamed A. Abdelgawad, Ahmed Khames, Hoon Kim
Publisher : Processes
Alagöz, M.A., Karakurt, A., Hepokur, C, Kim, H., Mathew, B. Synthesis of new 1-aryl-2-(3,5-dimethylpyrazol-1-yl)ethanone oxime ether derivatives and investigation of their cytotoxic effects, Processes, 2021, 9(11), 2019; https://doi.org/10.3390/pr9112019
Year : 2021
Selected Class of Enamides Bearing Nitro Functionality as Dual-Acting with Highly Selective Monoamine Oxidase-B and BACE1 Inhibitors
Authors : Dr. Bijo Mathew, Anusree Venkidath, Jong Min Oh, Sanal Dev, Elham Amin, Shebina P. Rasheed, Ajeesh Vengamthodi, Nicola Gambacorta, Ahmed Khames, Mohamed A. Abdelgawad, Ginson George, Orazio Nicolotti, Hoon Kim
Publisher : Molecules
Venkidath, A., Oh, J.M., Dev, S., (...), Kim, H., Mathew, B. Selected class of enamides bearing nitro functionality as dual-acting with highly selective monoamine oxidase-b and bace1 inhibitors, Molecules, Volume 26, Issue 19, 10.3390/molecules26196004
Year : 2021
An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.
Authors : Dr. Bijo Mathew, Harilal, Seetha; Musa, Arafa; Kumar, Rajesh; Parambi, Della Grace Thomas; Jose, Jobin; Uddin, Md Sahab; Shah, Muhammad Ajmal; Behl, Tapan; Unnikrishnan, Mazhuvancherry Kesavan
Publisher : Current Drug Targets
Bijo Mathew, Harilal, S., Musa, A., Kumar, R., Parambi, D. Grace Thom, Jose, J., Uddin, M. Sahab, Shah, M. Ajmal, Behl, T., and Unnikrishnan, M. Kesavan, “An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.”, Current Drug Targets, vol. 22, no. 7, pp. 823 - 834, 2021.
Year : 2021
A Comprehensive Overview of Colon Cancer- A Grim Reaper of the 21st Century
Authors : Dr. Bijo Mathew, Kumar, Rajesh; Harilal, Seetha; Carradori, Simone
Publisher : Current Medicinal Chemistry
R. Kumar, Harilal, S., Carradori, S., and Bijo Mathew, “A Comprehensive Overview of Colon Cancer- A Grim Reaper of the 21st Century”, Current Medicinal Chemistry, Volume 28, (14), pp. 2657-2696, (2021)
Year : 2021
Revealing the role of fluorine pharmacophore in chalcone scaffold for shifting the MAO-B selectivity: investigation of a detailed molecular dynamics and quantum chemical study.
Authors : Dr. Bijo Mathew, Olotu, Fisayo A; Joy, Monu; Abdelgawad, Mohamed A; Narayanan, Siju E; Soliman, Mahmoud E; Bijo Mathew
Publisher : Journal of Biomolecular Structure and Dynamics
F. A. Olotu, Joy, M., Abdelgawad, M. A., Narayanan, S. E., Soliman, M. E., and Bijo Mathew, “Revealing the role of fluorine pharmacophore in chalcone scaffold for shifting the MAO-B selectivity: investigation of a detailed molecular dynamics and quantum chemical study.”, Journal of Biomolecular Structure and Dynamics 2021, 39(16), pp. 6126-6139
Year : 2021
Development of methylthiosemicarbazones as new reversible monoamine oxidase-B inhibitors for the treatment of Parkinson’s disease.
Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Oh, Jong Min; Mohan, Kumar; Tengli, Anandkumar; Bijo Mathew; Kim, Hoon
Publisher : Journal of Biomolecular Structure and Dynamics
G. Elizabeth Mathew, Oh, J. Min, Mohan, K., Tengli, A., Bijo Mathew, and Kim, H., “Development of methylthiosemicarbazones as new reversible monoamine oxidase-B inhibitors for the treatment of Parkinson's disease.”, Journal of Biomolecular Structure and Dynamics, 2021, 39(13), pp. 4786-4794.
Year : 2021
Navigating into the chemical space of monoamine oxidase inhibitors by artificial intelligence and chemoinformatics approach
Authors : Dr. Bijo Mathew, Kumar S, Nair AS, Bhaskar V, Sudevan TS, Vishal PK, Khames A, Abdelgawad MA
Publisher : ACS OMEGA
Kumar S, Nair AS, Bhaskar V, Sudevan TS, Vishal PK, Khames A, Abdelgawad MA, and Bijo Mathew, “Navigating into the chemical space of monoamine oxidase inhibitors by artificial intelligence and chemoinformatics approach”, ACS OMEGA [Accepted], 2021.
Year : 2021
An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.
Authors : Dr. Bijo Mathew, Harilal, Seetha; Musa, Arafa; Kumar, Rajesh; Parambi, Della Grace Thomas; Jose, Jobin; Uddin, Md Sahab; Shah, Muhammad Ajmal; Behl, Tapan; Unnikrishnan, Mazhuvancherry Kesavan
Publisher : Current Drug Targets
Bijo Mathew, Harilal, S., Musa, A., Kumar, R., Parambi, D. Grace Thom, Jose, J., Uddin, M. Sahab, Shah, M. Ajmal, Behl, T., and Unnikrishnan, M. Kesavan, “An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.”, Current Drug Targets, vol. 22, no. 7, pp. 823 - 834, 2021.
Year : 2021
Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations.
Authors : Dr. Bijo Mathew, Sasidharan, Rani; Eom, Bo Hyun; Heo, Jeong Hyun; Park, Jong Eun; Abdelgawad, Mohamed A; Musa, Arafa; Gambacorta, Nicola; Nicolotti, Orazio; Manju, Sreedharannair Leelabaiamma; Kim, Hoon
Publisher : Journal of Enzyme Inhibition and Medicinal Chemistry
R. Sasidharan, Eom, B. Hyun, Heo, J. Hyun, Park, J. Eun, Abdelgawad, M. A., Musa, A., Gambacorta, N., Nicolotti, O., Manju, S. Leelabaiam, Bijo Mathew, and Kim, H., “Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: synthesis and biochemical investigations.”, Journal of Enzyme Inhibition and Medicinal Chemistry, vol. 36, no. 1, pp. 188-197, 2021.
Year : 2021
Recent updates on pyrazolines derivatives as promising candidates for neuropsychiartic and neurodegenerative disorders
Authors : Dr. Bijo Mathew, Rangarajan TM
Publisher : Current Topics in Medicinal Chemistry
Rangarajan TM and Bijo Mathew, “Recent updates on pyrazolines derivatives as promising candidates for neuropsychiartic and neurodegenerative disorders”, Current Topics in Medicinal Chemistry, 2021;21(30):2695-2714, DOI: 10.2174/1568026621999210902123132
Year : 2021
COVID-19 and domestic animals: Exploring the species barrier crossing, zoonotic and reverse zoonotic transmission of SARS-CoV-2.
Authors : Dr. Bijo Mathew, Kumar, Rajesh; Harilal, Seetha; Al-Sehemi, Abdullah G; Paninipara, Mehboobali; Behl, Tapan; Mathew, Githa Elizabeth
Publisher : Curr Pharm Des
R. Kumar, Harilal, S., Al-Sehemi, A. G., Paninipara, M., Behl, T., Mathew, G. Elizabeth, and Bijo Mathew, “COVID-19 and domestic animals: Exploring the species barrier crossing, zoonotic and reverse zoonotic transmission of SARS-CoV-2.”, Current Pharmaceutical Design, Volume 27, Issue 9, pp. 1194-1201, (2021)
Year : 2021
Ameliorative effect of ethoxylated chalcone based MAO-B inhibitor on behavioural predictors of Haloperidol-induced Parkinsonism in mice: Evidence of its anti-oxidative role against Parkinson’s diseases
Authors : Dr. Bijo Mathew, Maliyakkal N, Saleem U, Anwar F, Shah FA, Ahmad B, Umer F, Almoyad MAA, DGT, P., Beeran AP, Nath LR, Aleya L
Publisher : Environmental Science and Pollution Research
Maliyakkal N, Saleem U, Anwar F, Shah FA, Ahmad B, Umer F, Almoyad MAA, DGT, P., Beeran AP, Nath LR, Aleya L, and Bijo Mathew, “Ameliorative effect of ethoxylated chalcone based MAO-B inhibitor on behavioural predictors of Haloperidol-induced Parkinsonism in mice: Evidence of its anti-oxidative role against Parkinson’s diseases”, Environmental Science and Pollution Research. [Accepted], 2021.
Year : 2021
Dysregulation of the Gut-Brain Axis, Dysbiosis and Influence of Numerous Factors on Gut Microbiota Associated Parkinson’s Disease
Authors : Dr. Bijo Mathew, Kaur, Gagandeep; Behl, Tapan; Bungau, Simona; Kumar, Arun; Uddin, Md Sahab; Mehta, Vineet; Zengin, Gokhan; Bijo Mathew; Shah, Muhammad Ajmal; Arora, Sandeep
Publisher : Curr Neuropharmacol
G. Kaur, Behl, T., Bungau, S., Kumar, A., Uddin, M. Sahab, Mehta, V., Zengin, G., Bijo Mathew, Shah, M. Ajmal, and Arora, S., “Dysregulation of the Gut-Brain Axis, Dysbiosis and Influence of Numerous Factors on Gut Microbiota Associated Parkinson's Disease.”, Curr Neuropharmacol, vol. 19, no. 2, pp. 233-247, 2021.
Year : 2021
The Chronicle of COVID-19 and Possible Strategies to Curb the Pandemic
Authors : Dr. Bijo Mathew, Kumar, Rajesh; Harilal, Seetha; Al-Sehemi, Abdullah G; Mathew, Githa Elizabeth; Carradori, Simone
Publisher : Curr Med Chem,
R. Kumar, Harilal, S., Al-Sehemi, A. G., Mathew, G. Elizabeth, Carradori, S., and Bijo Mathew, “The Chronicle of COVID-19 and Possible Strategies to Curb the Pandemic”, Current Medicinal Chemistry, 2021, 28(15), pp. 2852-2886
Year : 2021
Insights into an Immunotherapeutic Approach to Combat Multidrug Resistance in Hepatocellular Carcinoma
Authors : Dr. Bijo Mathew, Devan AR; Kumar AR; Nair B; Anto NP; Muraleedharan A; Bijo Mathew; Kim H; Nath LR
Publisher : Pharmaceuticals
Devan AR, Kumar AR, Nair B, Anto NP, Muraleedharan A, Bijo Mathew, Kim H, and Nath LR, “Insights into an Immunotherapeutic Approach to Combat Multidrug Resistance in Hepatocellular Carcinoma”, Pharmaceuticals, vol. 14, no. 7, p. 656, 2021.
Year : 2021
New Aspects of Monoamine Oxidase B Inhibitors: The Key Role of Halogens to Open the Golden Door.
Authors : Dr. Bijo Mathew, Carradori, Simone; Guglielmi, Paolo; Uddin, Md Sahab; Kim, Hoon
Publisher : Current Medicinal Chemistry
Bijo Mathew, Carradori, S., Guglielmi, P., Uddin, M. Sahab, and Kim, H., “New Aspects of Monoamine Oxidase B Inhibitors: The Key Role of Halogens to Open the Golden Door.”, Current Medicinal Chemistry, 2021, 28(2), pp. 266-283
Year : 2021
Current Progress in Quinazoline Derivatives as Acetylcholinesterase and Monoamine Oxidase Inhibitors
Authors : Dr. Bijo Mathew, Rehuman, Nisha Abdul; Al-Sehemi, Abdullah G.; Parambi, Della Grace Thomas; Rangarajan, T. M.; Nicolotti, Orazio; Kim, Hoon
Publisher : ChemistrySelect
N. Abdul Rehuman, Al-Sehemi, A. G., Parambi, D. Grace Thom, Rangarajan, T. M., Nicolotti, O., Kim, H., and Bijo Mathew, “Current Progress in Quinazoline Derivatives as Acetylcholinesterase and Monoamine Oxidase Inhibitors”, ChemistrySelect, vol. 6, no. 28, pp. 7162-7182, 2021. DOI: https://doi.org/10.1002/slct.202101077
Year : 2021
Deciphering the detailed structure – activity relationship of coumarins as Monoamine oxidase enzyme inhibitors – An updated review.
Authors : Dr. Bijo Mathew, Vishal Payyalot Koyiparambath; Krishnendu Pr; M RangarajanT; A. Al-Sehemi; M. Pannipara; Vaishnav Bhaskar; Aathira Sujathan Nair; Sachithra Thazhathuveedu Sudevan; Sunil Kumar
Publisher : Wiley-VCH
V. Payyalot Koyiparambath, Pr, K., RangarajanT, M., Al-Sehemi, A., Pannipara, M., Bhaskar, V., Nair, A. Sujathan, Sudevan, S. Thazhathuv, Kumar, S., and Bijo Mathew, “Deciphering the detailed structure-activity relationship of coumarins as Monoamine oxidase enzyme inhibitors-An updated review.”, Chemical Biology and Drug Design, Wiley-VCH (2021), 98(4), pp. 655-673
Year : 2021
Synthesis of N ′-(4-/3-/2-/Non-substituted benzylidene)-4-[(4-methylphenyl)sulfonyloxy] Benzohydrazides and Evaluation of Their Inhibitory Activities against Monoamine Oxidases and β-Secretase.
Authors : Dr. Bijo Mathew, H. Erdinç Sellitepe, Oh, J. Min, Doğan, İ. Selin, Yildirim, S., Aksel, A. Buğra, Jeong, G. Seok, Khames, A., Abdelgawad, M. A., Gambacorta, N., Nicolotti, O., Bijo Mathew, and Kim, H.
Publisher : Applied Sciences
H. Erdinç Sellitepe, Oh, J. Min, Doğan, İ. Selin, Yildirim, S., Aksel, A. Buğra, Jeong, G. Seok, Khames, A., Abdelgawad, M. A., Gambacorta, N., Nicolotti, O., Bijo Mathew, and Kim, H., “Synthesis of N ′-(4-/3-/2-/Non-substituted benzylidene)-4-[(4-methylphenyl)sulfonyloxy] Benzohydrazides and Evaluation of Their Inhibitory Activities against Monoamine Oxidases and β-Secretase.”, Applied Sciences (2076-3417) , vol. 11, no. 13, pp. 5830-5830, 2021.
Year : 2021
Current perspective of COVID-19 on neurology: A mechanistic insight.
Authors : Dr. Bijo Mathew, Kumar, Rajesh; Harilal, Seetha; Pappachan, Leena K;
Publisher : Bentham Science
R. Kumar, Harilal, S., Pappachan, L. K., and Bijo Mathew, “Current perspective of COVID-19 on neurology: A mechanistic insight.”, Combinatorial Chemistry and High Throughput Screening (Accepted), 2021.
Year : 2021
Development of 2D, 3D-QSAR and pharmacophore modeling of chalcones for the inhibition of monoamine oxidase B.
Authors : Dr. Bijo Mathew, Acevedo, C. H., Sc, D., Rangarajan TM, MS, K., NP, N. Punnoth Po, L, S., and MT., S
Publisher : Combinatorial Chemistry and High Throughput Screening
Bijo Mathew, Acevedo, C. H., Sc, D., Rangarajan TM, MS, K., NP, N. Punnoth Po, L, S., and MT., S., “Development of 2D, 3D-QSAR and pharmacophore modeling of chalcones for the inhibition of monoamine oxidase B. ”, Combinatorial Chemistry and High Throughput Screening. (Accepted), 2021.
Year : 2021
Trimethoxylated Halogenated Chalcones as Dual Inhibitors of MAO-B and BACE-1 for the Treatment of Neurodegenerative Disorders.
Authors : Dr. Bijo Mathew, Dr Lekshmi.R.Nath, Vishal, Payyalot Koyiparambath; Oh, Jong Min; Khames, Ahmed; Abdelgawad, Mohamed A; Nair, Aathira Sujathan; Gambacorta, Nicola; Ciriaco, Fulvio; Nicolotti, Orazio; Kim, Hoon
Publisher : Pharmaceutics
P. Koyiparamb Vishal, Oh, J. Min, Khames, A., Abdelgawad, M. A., Nair, A. Sujathan, Nath, L. R., Gambacorta, N., Ciriaco, F., Nicolotti, O., Kim, H., and Bijo Mathew, “Trimethoxylated Halogenated Chalcones as Dual Inhibitors of MAO-B and BACE-1 for the Treatment of Neurodegenerative Disorders.”, Pharmaceutics, vol. 13, no. 6, 2021.
Year : 2021
Targeting cellular batteries for the therapy of neurological diseases
Authors : Dr. Bijo Mathew, Arpita Arora, Tapan Behl, Aayush Sehgal, Sukhbir Singh, Neelam Sharma & Simona Bungau
Publisher : Springer Nature
A. Arora, Behl, T., Sehgal, A., Singh, S., Sharma, N., Bijo Mathew, and Bungau, S., “Targeting cellular batteries for the therapy of neurological diseases”, vol. 28, no. 31, pp. 41517 - 41532, 2021.
Year : 2021
Trimethoxy Crown Chalcones as Multifunctional Class of Monoamine Oxidase Enzyme Inhibitors.
Authors : Dr. Bijo Mathew, Maliyakkal, Naseer; Baysal, Ipek; Tengli, Anandkumar; Ucar, Gülberk; Almoyad, Mohammad Ali Abdullah; Parambi, Della Grace Thomas; Gambacorta, Nicola; Nicolotti, Orazio; Beeran, Asmy Appadath
Publisher : Bentham Science
N. Maliyakkal, Baysal, I., Tengli, A., Ucar, G., Almoyad, M. Ali Abdull, Parambi, D. Grace Thom, Gambacorta, N., Nicolotti, O., Beeran, A. Appadath, and Bijo Mathew, “Trimethoxy Crown Chalcones as Multifunctional Class of Monoamine Oxidase Enzyme Inhibitors.”, Combinatorial Chemistry and High Throughput Screening, 2021.
Year : 2021
An Update of Synthetic Approaches and Structure-Activity Relationships of Various Classes of Human MAO-B Inhibitors
Authors : Dr. Bijo Mathew, Pratibha Sharma; Dr. Manjinder Singh;
Publisher : ChemistrySelect
P. Sharma, Singh, D. Manjinder, and Bijo Mathew, “An Update of Synthetic Approaches and Structure-Activity Relationships of Various Classes of Human MAO-B Inhibitors”, ChemistrySelect, vol. 6, no. 7, pp. 1404-1429, 2021.
Year : 2021
Synthesis, Cytotoxicity and Anti-Proliferative Activity Against AGS Cells of New 3(2)-Pyridazinone Derivatives Endowed with a Piperazinyl Linker.
Authors : Dr. Bijo Mathew, Alagöz, Mehmet Abdullah; Özdemir, Zeynep; Uysal, Mehtap; Carradori, Simone; Gallorini, Marialucia; Ricci, Alessia; Zara, Susi
Publisher : Basel
M. Abdullah Alagöz, Özdemir, Z., Uysal, M., Carradori, S., Gallorini, M., Ricci, A., Zara, S., and Bijo Mathew, “Synthesis, Cytotoxicity and Anti-Proliferative Activity Against AGS Cells of New 3(2)-Pyridazinone Derivatives Endowed with a Piperazinyl Linker.”, Pharmaceuticals (Basel), Volume 14, Issue 3, 183, pp. 1-27 (2021)
Year : 2021
Neuroprotective Effects of Ellagic Acid in Alzheimer’s Disease: Focus on Underlying Molecular Mechanisms of Therapeutic Potential.
Authors : Dr. Bijo Mathew, Nimra Javaid, Muhammad A. Shah, Azhar Rasul, Zunera Chauhdary, Uzma Saleem, Haroon Khan, Nazir Ahmed, Md. Sahab Uddin, Tapan Behl, Renald Blundell
Publisher : Bentham Science Publishers
N. Javaid, Shah, M. Ajmal, Rasul, A., Chauhdary, Z., Saleem, U., Khan, H., Ahmed, N., Uddin, M. Sahab, Bijo Mathew, Behl, T., and Blundell, R., “Neuroprotective Effects of Ellagic Acid in Alzheimer's Disease: Focus on Underlying Molecular Mechanisms of Therapeutic Potential.”, Current Pharmaceutical Design, Bentham Science Publishers, 2021, 27(34), pp. 3591-3601
Year : 2021
Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach.
Authors : Dr. Bijo Mathew, Nair, Aathira Sujathan; Oh, Jong-Min; Koyiparambath, Vishal Payyalot; Sunil Kumar; Sudevan, Sachithra Thazhathuveedu; Soremekun, Opeyemi; Soliman, Mahmoud E; Khames, Ahmed; Abdelgawad, Mohamed A; Pappachen, Leena K; Kim, Hoon
Publisher : Molecules
A. Sujathan Nair, Oh, J. - M., Koyiparambath, V. Payyalot, Sunil Kumar, Sudevan, S. Thazhathuv, Soremekun, O., Soliman, M. E., Khames, A., Abdelgawad, M. A., Pappachen, L. K., Bijo Mathew, and Kim, H., “Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach.”, Molecules, vol. 26, no. 11, 2021.
Year : 2021
Nanotechnology-Based Approaches and Investigational Therapeutics against COVID-19.
Authors : Dr. Bijo Mathew, Rahman, Md Mominur; Ahmed, Muniruddin; Islam, Mohammad Touhidul; Khan, Md Robin; Sultana, Sharifa; Maeesa, Saila Kabir; Hasan, Sakib; Hossain, Md Abid; Ferdous, Kazi Sayma; Rauf, Abdur; Uddin, Md Sahab
Publisher : Current Pharmaceutical Design
M. Mominur Rahman, Ahmed, M., Islam, M. Touhidul, Khan, M. Robin, Sultana, S., Maeesa, S. Kabir, Hasan, S., Hossain, M. Abid, Ferdous, K. Sayma, Bijo Mathew, Rauf, A., and Uddin, M. Sahab, “Nanotechnology-Based Approaches and Investigational Therapeutics against COVID-19.”, Current Pharmaceutical Design, 2021.
Year : 2021
Therapeutic Potential of Polyphenols in the Management of Diabetic Neuropathy.
Authors : Dr. Bijo Mathew, Kabir, Md Tanvir; Tabassum, Nuzhat; Uddin, Md Sahab; Aziz, Faissal; Behl, Tapan; Rahman, Md Habibur; Akter, Raushanara; Rauf, Abdur; Aleya, Lotfi
Publisher : Evidence based Complementary and Alternative Medicine
M. Tanvir Kabir, Tabassum, N., Uddin, M. Sahab, Aziz, F., Behl, T., Bijo Mathew, Rahman, M. Habibur, Akter, R., Rauf, A., and Aleya, L., “Therapeutic Potential of Polyphenols in the Management of Diabetic Neuropathy.”, Evidence based Complementary and Alternative Medicine, vol. 2021, p. 9940169, 2021.
Year : 2021
Piperazine-substituted chalcones: a new class of MAO-B, AChE, and BACE-1 inhibitors for the treatment of neurological disorders
Authors : Dr. Bijo Mathew, Jong Min Oh, Roua S. Baty, Gaber El-Saber Batiha, Della Grace Thomas Parambi, Nicola Gambacorta, Orazio Nicolotti & Hoon Kim
Publisher : Environmental Science and Pollution Research
Bijo Mathew, Oh, J. Min, Baty, R. S., Batiha, G. El- Saber, Parambi, D. Grace Thom, Gambacorta, N., Nicolotti, O., and Kim, H., “Piperazine-substituted chalcones: a new class of MAO-B, AChE, and BACE-1 inhibitors for the treatment of neurological disorders”, Environmental Science and Pollution Research, 2021, 28(29), pp. 38855-38866.
Year : 2021
Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development.
Authors : Dr. Bijo Mathew, Meduri, Bhagyalalitha; Pujar, Gurubasavaraj Veeranna; Durai Ananda Kumar, T; Akshatha, H S; Sethu, Arun Kumar; Singh, Manisha; Kanagarla, Abhinav
Publisher : ELSEVIER
B. Meduri, Pujar, G. Veeranna, T Kumar, D. Ananda, Akshatha, H. S., Sethu, A. Kumar, Singh, M., Kanagarla, A., and Bijo Mathew, “Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development.”, Eur J Med Chem, vol. 222, p. 113574, 2021.
Year : 2020
Design, Synthesis, and Biological Evaluation of Pyridazinones Containing the (2-Fluorophenyl) Piperazine Moiety as Selective MAO-B Inhibitors
Authors : Dr. Bijo Mathew, Çeçen, Muhammed; Oh, Jong Min; Özdemir, Zeynep; Büyüktuncel, Saliha Ebru; Uysal, Mehtap; Abdelgawad, Mohamed A; Musa, Arafa; Gambacorta, Nicola; Nicolotti, Orazio; Kim, Hoon
Publisher : Molecules, Volume 25, Issue 22
M. Çeçen, Oh, J. Min, Özdemir, Z., Büyüktuncel, S. Ebru, Uysal, M., Abdelgawad, M. A., Musa, A., Gambacorta, N., Nicolotti, O., Mathew, B., and Kim, H., “Design, Synthesis, and Biological Evaluation of Pyridazinones Containing the (2-Fluorophenyl) Piperazine Moiety as Selective MAO-B Inhibitors.”, Molecules, vol. 25, no. 22, p. 5371, 2020.
Year : 2020
Exploring the Therapeutic Potentials of Highly Selective Oxygenated Chalcone Based MAO-B Inhibitors in a Haloperidol-Induced Murine Model of Parkinson’s Disease
Authors : Dr. Bijo Mathew, Parambi, Della Grace Thomas; Saleem, Uzma; Shah, Muhammad Ajmal; Anwar, Fareeha; Ahmad, Bashir; Manzar, Amna; Itzaz, Aqsa; Harilal, Seetha; Uddin, Md Sahab; Kim, Hoon; Bijo Mathew
Publisher : Neurochemical Research
D. Grace Thom Parambi, Saleem, U., Shah, M. Ajmal, Anwar, F., Ahmad, B., Manzar, A., Itzaz, A., Harilal, S., Uddin, M. Sahab, Kim, H., and Bijo Mathew, “Exploring the Therapeutic Potentials of Highly Selective Oxygenated Chalcone Based MAO-B Inhibitors in a Haloperidol-Induced Murine Model of Parkinson’s Disease”, Neurochemical Research, vol. 45, no. 11, pp. 2786 - 2799, 2020.
Year : 2020
A New Potent and Selective Monoamine Oxidase-B Inhibitor with Extended Conjugation in a Chalcone Framework: 1-[4-(Morpholin-4-yl)phenyl]-5-phenylpenta-2,4-dien-1-one.
Authors : Dr. Bijo Mathew, Maliyakkal, Naseer; Eom, Bo Hyun; Heo, Jeong Hyun; Abdullah Almoyad, Mohammad Ali; Thomas Parambi, Della Grace; Gambacorta, Nicola; Nicolotti, Orazio; Beeran, Asmy Appadath; Kim, Hoon; Bijo Mathew
Publisher : ChemMedChem
N. Maliyakkal, Eom, B. Hyun, Heo, J. Hyun, Almoyad, M. Ali Abdull, Parambi, D. Grace Thom, Gambacorta, N., Nicolotti, O., Beeran, A. Appadath, Kim, H., and Bijo Mathew, “A New Potent and Selective Monoamine Oxidase-B Inhibitor with Extended Conjugation in a Chalcone Framework: 1-[4-(Morpholin-4-yl)phenyl]-5-phenylpenta-2,4-dien-1-one.”, ChemMedChem, vol. 15, no. 17, pp. 1629-1633, 2020.
Year : 2020
(Hetero-)(arylidene)arylhydrazides as Multitarget-Directed Monoamine Oxidase Inhibitors
Authors : Dr. Bijo Mathew, Palakkathondi, Ashique; Oh, Jong Min; Dev, Sanal; Rangarajan, T. M.; Kaipakasseri, Swafvan; Kavully, Fathima Sahla; Gambacorta, Nicola; Nicolotti, Orazio; Kim, Hoon; Bijo Mathew
Publisher : American Chemical Society
A. Palakkathondi, Oh, J. Min, Dev, S., Rangarajan, T. M., Kaipakasseri, S., Kavully, F. Sahla, Gambacorta, N., Nicolotti, O., Kim, H., and Bijo Mathew, “(Hetero-)(arylidene)arylhydrazides as Multitarget-Directed Monoamine Oxidase Inhibitors”, ACS Combinatorial ScienceACS Combinatorial Science, vol. 22, no. 11, pp. 592 - 599, 2020.
Year : 2020
Natural Products Database Screening for the Discovery of Naturally Occurring SARS-Cov-2 Spike Glycoprotein Blockers
Authors : Dr. Bijo Mathew, Al-Sehemi, Abdullah G.; Olotu, Fisayo A.; Dev, Sanal; Pannipara, Mehboobali; Soliman, Mahmoud E.; Carradori, Simone; Bijo Mathew
Publisher : ChemistrySelect
A. G. Al-Sehemi, Olotu, F. A., Dev, S., Pannipara, M., Soliman, M. E., Carradori, S., and Bijo Mathew, “Natural Products Database Screening for the Discovery of Naturally Occurring SARS-Cov-2 Spike Glycoprotein Blockers”, ChemistrySelect, vol. 5, pp. 13309-13317, 2020.
Year : 2020
Revisiting the role of brain and peripheral Aβ in the pathogenesis of Alzheimer’s disease
Authors : Dr. Bijo Mathew, Md. Sahab Uddin; Md. Tanvir Kabir; Devesh Tewari; Abdullah Al Mamun; Bijo Mathew; Lotfi Aleya; George E. Barreto; May N. Bin-Jumah; Mohamed M. Abdel-Daim; Ghulam Md Ashraf
Publisher : Journal of the Neurological Sciences
M. Sahab Uddin, Kabir, M. Tanvir, Tewari, D., Mamun, A. Al, Bijo Mathew, Aleya, L., Barreto, G. E., Bin-Jumah, M. N., Abdel-Daim, M. M., and Ashraf, G. Md, “Revisiting the role of brain and peripheral Aβ in the pathogenesis of Alzheimer's disease”, Journal of the Neurological Sciences, vol. 416, p. 116974, 2020.
Year : 2020
Natural compounds from Leeamacrophyllaenhance phagocytosis and promote osteoblastsdifferentiationbyAlp, Type 1 collagen and Osteocalcin gene expression.
Authors : Dr. Bijo Mathew, Raiyan, Sayema; Rahman, Atiar; Al Mamun, Abdullah; Asim, Muzammal Haque; Makki, Arwa; Hajjar, Dina; Alelwani, Walla; Tangpong, Jitbanjong; Bijo Mathew
Publisher : Journal of Biomedical Materials Research Part A
S. Raiyan, Rahman, A., Mamun, A. Al, Asim, M. Haque, Makki, A., Hajjar, D., Alelwani, W., Tangpong, J., and Bijo Mathew, “Natural compounds from Leeamacrophyllaenhance phagocytosis and promote osteoblastsdifferentiationbyAlp, Type 1 collagen and Osteocalcin gene expression.”, Journal of Biomedical Materials Research Part A, 2020.
Year : 2020
Molecular mechanism of zinc neurotoxicity in Alzheimer’s disease
Authors : Dr. Bijo Mathew, Narayanan, Siju Ellickal; Rehuman, Nisha Abdul; Harilal, Seetha; Vincent, Anju; Rajamma, Rajalakshmi Ganesan; Behl, Tapan; Uddin, Md. Sahab; Ashraf, Ghulam Md; Bijo Mathew
Publisher : Environ Sci Pollut Res
S. Ellickal Narayanan, Rehuman, N. Abdul, Harilal, S., Vincent, A., Rajamma, R. Ganesan, Behl, T., Uddin, M. Sahab, Ashraf, G. Md, and Bijo Mathew, “Molecular mechanism of zinc neurotoxicity in Alzheimer’s disease”, Environ Sci Pollut Res, vol. 27, no. 35, pp. 43542 - 43552, 2020.
Year : 2020
Selected 1,3-Benzodioxine-Containing Chalcones as Multipotent Oxidase and Acetylcholinesterase Inhibitors.
Authors : Dr. Bijo Mathew, Jeong, Geum Seok; Kaipakasseri, Swafvan; Lee, Sang Ryong; Marraiki, Najat; Batiha, Gaber El-Saber; Dev, Sanal; Palakkathondi, Ashique; Kavully, Fathima Sahla; Gambacorta, Nicola; Nicolotti, Orazio; Bijo Mathew; Kim, Hoon
Publisher : ChemMedChem
G. Seok Jeong, Kaipakasseri, S., Lee, S. Ryong, Marraiki, N., Batiha, G. El- Saber, Dev, S., Palakkathondi, A., Kavully, F. Sahla, Gambacorta, N., Nicolotti, O., Bijo Mathew, and Kim, H., “Selected 1,3-Benzodioxine-Containing Chalcones as Multipotent Oxidase and Acetylcholinesterase Inhibitors.”, ChemMedChem, vol. 15, pp. 2257-2263, 2020.
Year : 2020
Chalcones: Unearthing their therapeutic possibility as monoamine oxidase B inhibitors
Authors : Dr. Bijo Mathew, Paolo Guglielmi; Bijo Mathew; Daniela Secci; Simone Carradori
Publisher : European Journal of Medicinal Chemistry
P. Guglielmi, Bijo Mathew, Secci, D., and Carradori, S., “Chalcones: Unearthing their therapeutic possibility as monoamine oxidase B inhibitors”, European Journal of Medicinal Chemistry, vol. 205, p. 112650, 2020.
Year : 2020
Synthesis and biological evaluation of new 3(2)-pyridazinone derivatives as non-toxic anti-proliferative compounds against human colon carcinoma HCT116 cells.
Authors : Dr. Bijo Mathew, Özdemir, Zeynep; Utku, Semra; Bijo Mathew; Carradori, Simone; Orlando, Giustino; Di Simone, Simonetta; Alagöz, Mehmet Abdullah; Özçelik, Azime Berna; Uysal, Mehtap; Ferrante, Claudio
Publisher : J Enzyme Inhib Med Chem
Z. Özdemir, Utku, S., Bijo Mathew, Carradori, S., Orlando, G., Di Simone, S., Alagöz, M. Abdullah, Özçelik, A. Berna, Uysal, M., and Ferrante, C., “Synthesis and biological evaluation of new 3(2)-pyridazinone derivatives as non-toxic anti-proliferative compounds against human colon carcinoma HCT116 cells.”, J Enzyme Inhib Med Chem, vol. 35, no. 1, pp. 1100-1109, 2020.
Year : 2020
Privileged Pharmacophore of FDA Approved Drugs in Combination with Chalcone Framework: A New Hope for Alzheimer’s Treatment.
Authors : Dr. Bijo Mathew
Publisher : Comb Chem High Throughput Screen
Bijo Mathew, “Privileged Pharmacophore of FDA Approved Drugs in Combination with Chalcone Framework: A New Hope for Alzheimer's Treatment.”, Comb Chem High Throughput Screen, vol. 23, no. 9, pp. 842-846, 2020.
Year : 2020
Design of enamides as new selective monoamine oxidase-B inhibitors
Authors : Dr. Bijo Mathew, Kavully, Fathima Sahla; Oh, Jong Min; Dev, Sanal; Kaipakasseri, Swafvan; Palakkathondi, Ashique; Vengamthodi, Ajeesh; Abdul Azeez, Rinshana Fathima; Tondo, Anna Rita; Nicolotti, Orazio; Kim, Hoon; Bijo Mathew
Publisher : Journal of Pharmacy and Pharmacology
F. Sahla Kavully, Oh, J. Min, Dev, S., Kaipakasseri, S., Palakkathondi, A., Vengamthodi, A., Azeez, R. Fathima Ab, Tondo, A. Rita, Nicolotti, O., Kim, H., and Bijo Mathew, “Design of enamides as new selective monoamine oxidase-B inhibitors”, Journal of Pharmacy and Pharmacology, vol. 72, pp. 916-926, 2020.
Year : 2020
Molecular Insight into the Therapeutic Promise of Targeting for Alzheimer’s Disease.
Authors : Dr. Bijo Mathew, Mamun, Abdullah Al; Uddin, Md Sahab; Bin Bashar, Md Fahim; Zaman, Sonia; Begum, Yesmin; Bulbul, Israt Jahan; Islam, Md Siddiqul; Sarwar, Md Shahid; Bijo Mathew; Amran, Md Shah; Md Ashraf, Ghulam; Bin-Jumah, May N; Mousa, Shaker A; Abdel-Daim, Mohamed M
Publisher : Oxid Med Cell Longev
A. Al Mamun, Uddin, M. Sahab, Bin Bashar, M. Fahim, Zaman, S., Begum, Y., Bulbul, I. Jahan, Islam, M. Siddiqul, Sarwar, M. Shahid, Bijo Mathew, Amran, M. Shah, Ashraf, G. Md, Bin-Jumah, M. N., Mousa, S. A., and Abdel-Daim, M. M., “Molecular Insight into the Therapeutic Promise of Targeting for Alzheimer's Disease.”, Oxid Med Cell Longev, vol. 2020, p. 5086250, 2020.
Year : 2020
Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors.
Authors : Dr. Bijo Mathew, Oh, Jong Min; Rangarajan, T M; Chaudhary, Reeta; Singh, Rishi Pal; Singh, Manjula; Singh, Raj Pal; Tondo, Anna Rita; Gambacorta, Nicola; Nicolotti, Orazio; Bijo Mathew; Kim, Hoon
Publisher : Molecules
J. Min Oh, Rangarajan, T. M., Chaudhary, R., Singh, R. Pal, Singh, M., Singh, R. Pal, Tondo, A. Rita, Gambacorta, N., Nicolotti, O., Bijo Mathew, and Kim, H., “Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors.”, Molecules, vol. 25, no. 10, 2020.
Year : 2020
Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer’s disease
Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Rahman, Md Ataur; Kabir, Md Tanvir; Behl, Tapan; Bijo Mathew; Perveen, Asma; Barreto, George E; Bin-Jumah, May N; Abdel-Daim, Mohamed M; Ashraf, Ghulam Md
Publisher : IUBMB Life
M. Sahab Uddin, Rahman, M. Ataur, Kabir, M. Tanvir, Behl, T., Bijo Mathew, Perveen, A., Barreto, G. E., Bin-Jumah, M. N., Abdel-Daim, M. M., and Ashraf, G. Md, “Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer's disease.”, IUBMB Life, vol. 72, no. 9, pp. 1843-1855, 2020.
Year : 2020
Emerging Promise of Immunotherapy for Alzheimer’s Disease: A New Hope for the Development of Alzheimer’s Vaccine.
Authors : Dr. Bijo Mathew, Kabir, Md Tanvir; Uddin, Md Sahab; Bijo Mathew; Das, Pankoj Kumar; Perveen, Asma; Ashraf, Ghulam Md
Publisher : Curr Top Med Chem
M. Tanvir Kabir, Uddin, M. Sahab, Bijo Mathew, Das, P. Kumar, Perveen, A., and Ashraf, G. Md, “Emerging Promise of Immunotherapy for Alzheimer's Disease: A New Hope for the Development of Alzheimer's Vaccine.”, Curr Top Med Chem, vol. 20, no. 13, pp. 1214-1234, 2020.
Year : 2020
Combination Drug Therapy for the Management of Alzheimer’s Disease.
Authors : Dr. Bijo Mathew, Kabir, Md Tanvir; Uddin, Md Sahab; Mamun, Abdullah Al; Jeandet, Philippe; Aleya, Lotfi; Mansouri, Rasha A; Ashraf, Ghulam Md; Bijo Mathew; Bin-Jumah, May N; Abdel-Daim, Mohamed M
Publisher : Int J Mol Sci
M. Tanvir Kabir, Uddin, M. Sahab, Mamun, A. Al, Jeandet, P., Aleya, L., Mansouri, R. A., Ashraf, G. Md, Bijo Mathew, Bin-Jumah, M. N., and Abdel-Daim, M. M., “Combination Drug Therapy for the Management of Alzheimer's Disease.”, Int J Mol Sci, vol. 21, no. 9, 2020.
Year : 2020
Fascinating chemo preventive story of wogonin: A chance to hit on the head in cancer treatment.
Authors : Dr. Bijo Mathew, Kumar, Rajesh; Harilal, Seetha; Parambi, Della Grace Thomas; Narayanan, Siju E; Uddin, Md Sahab; Marathakam, Akash; Jose, Jobin; Mathew, Githa Elizabeth; Bijo Mathew
Publisher : Curr Pharm Des
R. Kumar, Harilal, S., Parambi, D. Grace Thom, Narayanan, S. E., Uddin, M. Sahab, Marathakam, A., Jose, J., Mathew, G. Elizabeth, and Bijo Mathew, “Fascinating chemo preventive story of wogonin: A chance to hit on the head in cancer treatment.”, Curr Pharm Des, 2020.
Year : 2020
Novel Anti-Alzheimer’s Therapeutic Molecules Targeting Amyloid Precursor Protein Processing.
Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Kabir, Md Tanvir; Jeandet, Philippe; Bijo Mathew; Ashraf, Ghulam Md; Perveen, Asma; Bin-Jumah, May N; Mousa, Shaker A; Abdel-Daim, Mohamed M
Publisher : Oxid Med Cell Longev
M. Sahab Uddin, Kabir, M. Tanvir, Jeandet, P., Bijo Mathew, Ashraf, G. Md, Perveen, A., Bin-Jumah, M. N., Mousa, S. A., and Abdel-Daim, M. M., “Novel Anti-Alzheimer's Therapeutic Molecules Targeting Amyloid Precursor Protein Processing.”, Oxid Med Cell Longev, vol. 2020, p. 7039138, 2020.
Year : 2020
Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules
Authors : Dr. Bijo Mathew, Seetha Harilal; Jobin Jose; Della Grace Thomas Parambi; Rajesh Kumar; Mazhuvancherry Kesavan Unnikrishnan; Md. Sahab Uddin; Githa Elizabeth Mathew; Rahul Pratap; Akash Marathakam; Bijo Mathew
Publisher : Brain Research Bulletin
S. Harilal, Jose, J., Parambi, D. Grace Thom, Kumar, R., Unnikrishnan, M. Kesavan, Uddin, M. Sahab, Mathew, G. Elizabeth, Pratap, R., Marathakam, A., and Bijo Mathew, “Revisiting the blood-brain barrier: A hard nut to crack in the transportation of drug molecules”, Brain Research Bulletin, vol. 160, pp. 121-140, 2020.
Year : 2020
Inhibitions of monoamine oxidases and acetylcholinesterase by 1-methyl, 5-phenyl substituted thiosemicarbazones: Synthesis, biochemical, and computational investigations
Authors : Dr. Bijo Mathew, Githa Elizabeth Mathew; Jong Min Oh; Kumar Mohan; M.V. Kumudhavalli; Sivaraman Jayanthi; Hoon Kim; Bijo Mathew
Publisher : Process Biochemistry
G. Elizabeth Mathew, Oh, J. Min, Mohan, K., Kumudhavalli, M. V., Jayanthi, S., Kim, H., and Bijo Mathew, “Inhibitions of monoamine oxidases and acetylcholinesterase by 1-methyl, 5-phenyl substituted thiosemicarbazones: Synthesis, biochemical, and computational investigations”, Process Biochemistry, vol. 99, pp. 246-253, 2020.
Year : 2020
A Comprehensive Review of Monoamine Oxidase-A Inhibitors in their Syntheses and Potencies.
Authors : Dr. Bijo Mathew, Rehuman, Nisha A; Jat, Rakesh K; Nicolotti, Orazio; Kim, Hoon
Publisher : Comb Chem High Throughput Screen
N. A. Rehuman, Bijo Mathew, Jat, R. K., Nicolotti, O., and Kim, H., “A Comprehensive Review of Monoamine Oxidase-A Inhibitors in their Syntheses and Potencies.”, Comb Chem High Throughput Screen, vol. 23, no. 9, pp. 898-914, 2020.
Year : 2020
TV 3326 for Alzheimer’s dementia: a novel multimodal ChE and MAO inhibitors to mitigate Alzheimer’s-like neuropathology
Authors : Dr. Bijo Mathew, Uddin, Md. Sahab; Kabir, Md. Tanvir; Rahman, Md. Motiar; Bijo Mathew; Shah, Muhammad Ajmal; Ashraf, Ghulam Md
Publisher : Journal of Pharmacy and Pharmacology
M. Sahab Uddin, Kabir, M. Tanvir, Rahman, M. Motiar, Bijo Mathew, Shah, M. Ajmal, and Ashraf, G. Md, “TV 3326 for Alzheimer’s dementia: a novel multimodal ChE and MAO inhibitors to mitigate Alzheimer’s-like neuropathology”, Journal of Pharmacy and Pharmacology, vol. 72, pp. 1001-1012, 2020.
Year : 2020
Estrogen Signaling in Alzheimer’s Disease: Molecular Insights and Therapeutic Targets for Alzheimer’s Dementia.
Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Rahman, Md Motiar; Jakaria, Md; Rahman, Md Sohanur; Hossain, Md Sarwar; Islam, Ariful; Ahmed, Muniruddin; Bijo Mathew; Omar, Ulfat Mohammed; Barreto, George E; Ashraf, Ghulam Md
Publisher : Mol Neurobiol
M. Sahab Uddin, Rahman, M. Motiar, Jakaria, M., Rahman, M. Sohanur, Hossain, M. Sarwar, Islam, A., Ahmed, M., Bijo Mathew, Omar, U. Mohammed, Barreto, G. E., and Ashraf, G. Md, “Estrogen Signaling in Alzheimer's Disease: Molecular Insights and Therapeutic Targets for Alzheimer's Dementia.”, Mol Neurobiol, vol. 57, no. 6, pp. 2654-2670, 2020.
Year : 2020
Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer’s Disease.
Authors : Dr. Bijo Mathew, Narayanan, Siju Ellickal; Sekhar, Nikhila; Rajamma, Rajalakshmi Ganesan; Marathakam, Akash; Al Mamun, Abdullah; Uddin, Md Sahab; Bijo Mathew
Publisher : Curr Protein Pept Sci
S. Ellickal Narayanan, Sekhar, N., Rajamma, R. Ganesan, Marathakam, A., Mamun, A. Al, Uddin, M. Sahab, and Bijo Mathew, “Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer's Disease.”, Curr Protein Pept Sci, vol. 21, no. 12, pp. 1164-1173, 2020.
Year : 2020
Exploring the Promise of Targeting Ubiquitin-Proteasome System to Combat Alzheimer’s Disease.
Authors : Dr. Bijo Mathew, Al Mamun, Abdullah; Uddin, Md Sahab; Kabir, Md Tanvir; Khanum, Sayema; Sarwar, Md Shahid; Bijo Mathew; Rauf, Abdur; Ahmed, Muniruddin; Ashraf, Ghulam Md
Publisher : Neurotox Res
A. Al Mamun, Uddin, M. Sahab, Kabir, M. Tanvir, Khanum, S., Sarwar, M. Shahid, Bijo Mathew, Rauf, A., Ahmed, M., and Ashraf, G. Md, “Exploring the Promise of Targeting Ubiquitin-Proteasome System to Combat Alzheimer's Disease.”, Neurotox Res, vol. 38, no. 1, pp. 8-17, 2020.
Year : 2020
Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer’s Disease.
Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Kabir, Md Tanvir; Niaz, Kamal; Jeandet, Philippe; Clément, Christophe; Bijo Mathew; Rauf, Abdur; Rengasamy, Kannan R R; Sobarzo-Sánchez, Eduardo; Ashraf, Ghulam Md; Aleya, Lotfi
Publisher : Molecules
M. Sahab Uddin, Kabir, M. Tanvir, Niaz, K., Jeandet, P., Clément, C., Bijo Mathew, Rauf, A., Rengasamy, K. R. R., Sobarzo-Sánchez, E., Ashraf, G. Md, and Aleya, L., “Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer's Disease.”, Molecules, vol. 25, no. 6, 2020.
Year : 2020
Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety.
Authors : Dr. Bijo Mathew, Al-Sanea, Mohammad M; Gotina, Lizaveta; Mohamed, Mamdouh Fa; Grace Thomas Parambi, Della; Gomaa, Hesham A M; Bijo Mathew; Youssif, Bahaa G M; Alharbi, Khalid Saad; Elsayed, Zainab M; Abdelgawad, Mohamed A; Eldehna, Wagdy M
Publisher : Drug Des Devel Ther
M. M. Al-Sanea, Gotina, L., Mohamed, M. Fa, Parambi, D. Grace Thom, Gomaa, H. A. M., Bijo Mathew, Youssif, B. G. M., Alharbi, K. Saad, Elsayed, Z. M., Abdelgawad, M. A., and Eldehna, W. M., “Design, Synthesis and Biological Evaluation of New HDAC1 and HDAC2 Inhibitors Endowed with Ligustrazine as a Novel Cap Moiety.”, Drug Des Devel Ther, vol. 14, pp. 497-508, 2020.
Year : 2020
Exploring the Multifunctional Neuroprotective Promise of Rasagiline Derivatives for Multi-Dysfunctional Alzheimer’s Disease.
Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Kabir, Md Tanvir; Rahman, Md Habibur; Alim, Md Abdul; Rahman, Md Motiar; Khatkar, Anurag; Al Mamun, Abdullah; Rauf, Abdur; Bijo Mathew; Ashraf, Ghulam Md
Publisher : Curr Pharm Des
M. Sahab Uddin, Kabir, M. Tanvir, Rahman, M. Habibur, Alim, M. Abdul, Rahman, M. Motiar, Khatkar, A., Mamun, A. Al, Rauf, A., Bijo Mathew, and Ashraf, G. Md, “Exploring the Multifunctional Neuroprotective Promise of Rasagiline Derivatives for Multi-Dysfunctional Alzheimer's Disease.”, Curr Pharm Des, vol. 26, no. 37, pp. 4690-4698, 2020.
Year : 2020
Emerging promise of sulforaphane-mediated Nrf2 signaling cascade against neurological disorders.
Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Mamun, Abdullah Al; Jakaria, Md; Thangapandiyan, Shanmugam; Ahmad, Jamil; Rahman, Md Ataur; Bijo Mathew; Abdel-Daim, Mohamed M; Aleya, Lotfi
Publisher : Sci Total Environ
M. Sahab Uddin, Mamun, A. Al, Jakaria, M., Thangapandiyan, S., Ahmad, J., Rahman, M. Ataur, Bijo Mathew, Abdel-Daim, M. M., and Aleya, L., “Emerging promise of sulforaphane-mediated Nrf2 signaling cascade against neurological disorders.”, Sci Total Environ, vol. 707, p. 135624, 2020.
Year : 2020
Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery.
Authors : Dr. Bijo Mathew, Zahin, Nuzhat; Anwar, Raihanatul; Tewari, Devesh; Kabir, Md Tanvir; Sajid, Amin; Bijo Mathew; Uddin, Md Sahab; Aleya, Lotfi; Abdel-Daim, Mohamed M
Publisher : Environ Sci Pollut Res Int
N. Zahin, Anwar, R., Tewari, D., Kabir, M. Tanvir, Sajid, A., Bijo Mathew, Uddin, M. Sahab, Aleya, L., and Abdel-Daim, M. M., “Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery.”, Environ Sci Pollut Res Int, vol. 27, no. 16, pp. 19151-19168, 2020.
Year : 2020
Studies on the interaction between HSA and new halogenated metformin derivatives: influence of lipophilic groups in the binding ability.
Authors : Dr. Bijo Mathew, Chaves, Otávio Augusto; Bijo Mathew; Parambi, Della Grace Thomas; C S de Oliveira, Cosme Henrique; Cesarin-Sobrinho, Dari; Lakshminarayanan, Balasubramanian; Najeeb, Sadiya; Nafna, E K; Marathakam, Akash; Uddin, Md Sahab; Joy, Monu; Carlos Netto-Ferreira, José
Publisher : J Biomol Struct Dyn
O. Augusto Chaves, Bijo Mathew, Parambi, D. Grace Thom, de Oliveira, C. Henrique C., Cesarin-Sobrinho, D., Lakshminarayanan, B., Najeeb, S., Nafna, E. K., Marathakam, A., Uddin, M. Sahab, Joy, M., and Netto-Ferreira, J. Carlos, “Studies on the interaction between HSA and new halogenated metformin derivatives: influence of lipophilic groups in the binding ability.”, J Biomol Struct Dyn, vol. 38, no. 7, pp. 2128-2140, 2020.
Year : 2020
Toxic tau: structural origins of tau aggregation in Alzheimer’s disease.
Authors : Dr. Bijo Mathew, Mamun, Abdullah Al; Uddin, Md Sahab; Bijo Mathew; Ashraf, Ghulam Md
Publisher : Neural Regen Res
A. Al Mamun, Uddin, M. Sahab, Bijo Mathew, and Ashraf, G. Md, “Toxic tau: structural origins of tau aggregation in Alzheimer's disease.”, Neural Regen Res, vol. 15, no. 8, pp. 1417-1420, 2020.
Year : 2020
Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer’s disease.
Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Kabir, Md Tanvir; Tewari, Devesh; Bijo Mathew; Aleya, Lotfi
Publisher : Sci Total Environ
M. Sahab Uddin, Kabir, M. Tanvir, Tewari, D., Bijo Mathew, and Aleya, L., “Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer's disease.”, Sci Total Environ, vol. 700, p. 134836, 2020.
Year : 2020
Inhibitors of Monoamine Oxidase and Acetylcholinesterase as a Front Runner in CNS Drug Discovery
Authors : Dr. Bijo Mathew, Kim, H
Publisher : Comb Chem High Throughput Screen
Bijo Mathew and Kim, H., “Inhibitors of Monoamine Oxidase and Acetylcholinesterase as a Front Runner in CNS Drug Discovery.”, Comb Chem High Throughput Screen, vol. 23, no. 9, pp. 834-835, 2020.
Year : 2020
An Environment-friendly Synthesis of Piperonal Chalcones and Their Cytotoxic and Antioxidant Evaluation
Authors : Dr. Bijo Mathew, Dev, Sanal; Thomas Parambi, Della Grace; Baby, Bency; Mathew, Githa Elizabeth; Omnia Magdy, Hendawy; Joy, Monu; Sudev, Shine; Bijo Mathew
Publisher : Letters in Drug Design & Discovery
S. Dev, Parambi, D. Grace Thom, Baby, B., Mathew, G. Elizabeth, Magdy, H. Omnia, Joy, M., Sudev, S., and Bijo Mathew, “An Environment-friendly Synthesis of Piperonal Chalcones and Their Cytotoxic and Antioxidant Evaluation”, Letters in Drug Design & Discovery, vol. 17, pp. 138-144, 2020.
Year : 2020
Magnetic nanoparticles for hyperthermia in cancer treatment: an emerging tool.
Authors : Dr. Bijo Mathew, Jose, Jobin; Kumar, Rajesh; Harilal, Seetha; Mathew, Githa Elizabeth; Parambi, Della Grace Thomas; Prabhu, Ankitha; Uddin, Md Sahab; Aleya, Lotfi; Kim, Hoon; Bijo Mathew
Publisher : Environ Sci Pollut Res Int
J. Jose, Kumar, R., Harilal, S., Mathew, G. Elizabeth, Parambi, D. Grace Thom, Prabhu, A., Uddin, M. Sahab, Aleya, L., Kim, H., and Bijo Mathew, “Magnetic nanoparticles for hyperthermia in cancer treatment: an emerging tool.”, Environ Sci Pollut Res Int, vol. 27, no. 16, pp. 19214-19225, 2020.
Year : 2019
Emerging therapeutic potentials of dual-acting MAO and AChE inhibitors in Alzheimer’s and Parkinson’s diseases.
Authors : Dr. Bijo Mathew, Bijo Mathew; Parambi, Della G T; Mathew, Githa E; Uddin, Md Sahab; Inasu, Sini T; Kim, Hoon; Marathakam, Akash; Unnikrishnan, Mazhuvancherry Kesavan; Carradori, Simone
Publisher : Arch Pharm (Weinheim)
Bijo Mathew, Parambi, D. G. T., Mathew, G. E., Uddin, M. Sahab, Inasu, S. T., Kim, H., Marathakam, A., Unnikrishnan, M. Kesavan, and Carradori, S., “Emerging therapeutic potentials of dual-acting MAO and AChE inhibitors in Alzheimer's and Parkinson's diseases.”, Arch Pharm (Weinheim), vol. 352, no. 11, p. e1900177, 2019.
Year : 2019
Design, synthesis and biological evaluation of oxygenated chalcones as potent and selective MAO-B inhibitors.
Authors : Dr. Bijo Mathew, Parambi, Della Grace Thomas; Oh, Jong Min; Baek, Seung Cheol; Lee, Jae Pil; Tondo, Anna Rita; Nicolotti, Orazio; Kim, Hoon; Bijo Mathew
Publisher : Bioorg Chem
D. Grace Thom Parambi, Oh, J. Min, Baek, S. Cheol, Lee, J. Pil, Tondo, A. Rita, Nicolotti, O., Kim, H., and Bijo Mathew, “Design, synthesis and biological evaluation of oxygenated chalcones as potent and selective MAO-B inhibitors.”, Bioorg Chem, vol. 93, p. 103335, 2019.
Year : 2019
NMDA Receptor Antagonists: Repositioning of Memantine as a Multitargeting Agent for Alzheimer’s Therapy.
Authors : Dr. Bijo Mathew, Kabir, Md Tanvir; Sufian, Mohammad A; Uddin, Md Sahab; Begum, Mst Marium; Akhter, Shammi; Islam, Ariful; Islam, Md Siddiqul; Amran, Md Shah; Md Ashraf, Ghulam
Publisher : Curr Pharm Des
M. Tanvir Kabir, Sufian, M. A., Uddin, M. Sahab, Begum, M. Marium, Akhter, S., Islam, A., Bijo Mathew, Islam, M. Siddiqul, Amran, M. Shah, and Ashraf, G. Md, “NMDA Receptor Antagonists: Repositioning of Memantine as a Multitargeting Agent for Alzheimer's Therapy.”, Curr Pharm Des, vol. 25, no. 33, pp. 3506-3518, 2019.
Year : 2019
Ethyl Acetohydroxamate Incorporated Chalcones: Unveiling a Novel Class of Chalcones for Multitarget Monoamine Oxidase-B Inhibitors Against Alzheimer’s Disease.
Authors : Dr. Bijo Mathew, Baek, Seung Cheol; Lee, Jae Pil; Rangarajan, T M; Singh, Rishi Pal; Singh, Manjula; Mangiatordi, Giuseppe Felice; Nicolotti, Orazio; Kim, Hoon
Publisher : CNS Neurol Disord Drug Targets
S. Cheol Baek, Lee, J. Pil, Rangarajan, T. M., Singh, R. Pal, Singh, M., Mangiatordi, G. Felice, Nicolotti, O., Kim, H., and Bijo Mathew, “Ethyl Acetohydroxamate Incorporated Chalcones: Unveiling a Novel Class of Chalcones for Multitarget Monoamine Oxidase-B Inhibitors Against Alzheimer's Disease.”, CNS Neurol Disord Drug Targets, vol. 18, no. 8, pp. 643-654, 2019.
Year : 2019
Advancements in nanotherapeutics for Alzheimer’s disease: current perspectives.
Authors : Dr. Bijo Mathew, Harilal, Seetha; Jose, Jobin; Parambi, Della Grace Thomas; Kumar, Rajesh; Mathew, Githa Elizabeth; Uddin, Md Sahab; Kim, Hoon
Publisher : J Pharm Pharmacol
S. Harilal, Jose, J., Parambi, D. Grace Thom, Kumar, R., Mathew, G. Elizabeth, Uddin, M. Sahab, Kim, H., and Bijo Mathew, “Advancements in nanotherapeutics for Alzheimer's disease: current perspectives.”, J Pharm Pharmacol, vol. 71, no. 9, pp. 1370-1383, 2019.
Year : 2019
Aptamers in Drug Design: An Emerging Weapon to Fight a Losing Battle.
Authors : Dr. Bijo Mathew, Jose, Jobin; Thomas, Aaron Mathew; Mendonsa, Darewin; Al-Sanea, Mohammad M; Uddin, Md Sahab; Parambi, Della Grace Thomas; Charyulu, R Narayana; Bijo Mathew
Publisher : Curr Drug Targets
J. Jose, Thomas, A. Mathew, Mendonsa, D., Al-Sanea, M. M., Uddin, M. Sahab, Parambi, D. Grace Thom, R Charyulu, N., and Bijo Mathew, “Aptamers in Drug Design: An Emerging Weapon to Fight a Losing Battle.”, Curr Drug Targets, vol. 20, no. 16, pp. 1624-1635, 2019.
Year : 2019
Anti-inflammatory effect of synthesized indole-based chalcone (2E)-3-(4-bromophenyl)-1-(1-indol-3-yl) prop-2-en-1-one: an and studies.
Authors : Dr. Bijo Mathew, Sasidharan, Rani; Sreedharannair Leelabaiamma, Manju; Mohanan, Ratheesh; Jose, Svenia P; Bijo Mathew; Sukumaran, Sandya
Publisher : Immunopharmacol Immunotoxicol
R. Sasidharan, Leelabaiamma, M. Sreedharan, Mohanan, R., Jose, S. P., Bijo Mathew, and Sukumaran, S., “Anti-inflammatory effect of synthesized indole-based chalcone (2E)-3-(4-bromophenyl)-1-(1-indol-3-yl) prop-2-en-1-one: an and studies.”, Immunopharmacol Immunotoxicol, vol. 41, no. 6, pp. 568-576, 2019.
Year : 2019
Exploring the new horizons of drug repurposing: A vital tool for turning hard work into smart work.
Authors : Dr. Bijo Mathew, Kumar, Rajesh; Harilal, Seetha; Gupta, Sheeba Varghese; Jose, Jobin; Thomas Parambi, Della Grace; Uddin, Md Sahab; Shah, Muhammad Ajmal; Bijo Mathew
Publisher : Eur J Med Chem
R. Kumar, Harilal, S., Gupta, S. Varghese, Jose, J., Parambi, D. Grace Thom, Uddin, M. Sahab, Shah, M. Ajmal, and Bijo Mathew, “Exploring the new horizons of drug repurposing: A vital tool for turning hard work into smart work.”, Eur J Med Chem, vol. 182, p. 111602, 2019.
Year : 2019
Cholinesterase Inhibitors for Alzheimer’s Disease: Multitargeting Strategy Based on Anti-Alzheimer’s Drugs Repositioning.
Authors : Dr. Bijo Mathew, Kabir, Md Tanvir; Uddin, Md Sahab; Begum, Mst Marium; Thangapandiyan, Shanmugam; Rahman, Md Sohanur; Aleya, Lotfi; Bijo Mathew; Ahmed, Muniruddin; Barreto, George E; Ashraf, Ghulam Md
Publisher : Curr Pharm Des
M. Tanvir Kabir, Uddin, M. Sahab, Begum, M. Marium, Thangapandiyan, S., Rahman, M. Sohanur, Aleya, L., Bijo Mathew, Ahmed, M., Barreto, G. E., and Ashraf, G. Md, “Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning.”, Curr Pharm Des, vol. 25, no. 33, pp. 3519-3535, 2019.
Year : 2019
Perspective Design of Chalcones for the Management of CNS Disorders: A Mini-Review.
Authors : Dr. Bijo Mathew, Bijo Mathew; Parambi, Della Grace Thomas; Sivasankarapillai, Vishnu Sankar; Uddin, Md Sahab; Suresh, Jerad; Mathew, Githa Elizabeth; Joy, Monu; Marathakam, Akash; Gupta, Sheeba Varghese
Publisher : CNS Neurol Disord Drug Targets
Bijo Mathew, Parambi, D. Grace Thom, Sivasankarapillai, V. Sankar, Uddin, M. Sahab, Suresh, J., Mathew, G. Elizabeth, Joy, M., Marathakam, A., and Gupta, S. Varghese, “Perspective Design of Chalcones for the Management of CNS Disorders: A Mini-Review.”, CNS Neurol Disord Drug Targets, vol. 18, no. 6, pp. 432-445, 2019.
Year : 2019
Cholinesterase Inhibitory Activities of Selected Halogenated Thiophene Chalcones.
Authors : Dr. Bijo Mathew, Parambi, Della G T; Aljoufi, Fakhrya; Murugaiyah, Vikneswaran; Mathew, Githa E; Dev, Sanal; Lakshminarayanan, Balasubramanain; Hendawy, Omnia M; Bijo Mathew
Publisher : Cent Nerv Syst Agents Med Chem
D. G. T. Parambi, Aljoufi, F., Murugaiyah, V., Mathew, G. E., Dev, S., Lakshminarayanan, B., Hendawy, O. M., and Bijo Mathew, “Cholinesterase Inhibitory Activities of Selected Halogenated Thiophene Chalcones.”, Cent Nerv Syst Agents Med Chem, vol. 19, no. 1, pp. 67-71, 2019.
Year : 2019
Ethoxylated Head of Chalcones as a New Class of Multi-Targeted MAO Inhibitors
Authors : Dr. Bijo Mathew, Lakshminarayanan, Balasubramanian; Baek, Seung Cheol; Lee, Jae Pil; Kannappan, Nagappan; Mangiatordi, Giuseppe Felice; Nicolotti, Orazio; Subburaju, Thillainayagam; Kim, Hoon; Bijo Mathew
Publisher : ChemistrySelect
B. Lakshminarayanan, Baek, S. Cheol, Lee, J. Pil, Kannappan, N., Mangiatordi, G. Felice, Nicolotti, O., Subburaju, T., Kim, H., and Bijo Mathew, “Ethoxylated Head of Chalcones as a New Class of Multi-Targeted MAO Inhibitors”, ChemistrySelect, vol. 4, pp. 6614-6619, 2019.
Year : 2019
Melatonin in Alzheimer’s Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer’s Neuropathology
Authors : Dr. Bijo Mathew, Hossain, Md Farhad; Uddin, Md Sahab; Uddin, G M Sala; Sumsuzzman, Dewan Md; Islam, Md Siddiqul; Barreto, George E; Ashraf, Ghulam Md
Publisher : Mol Neurobiol
M. Farhad Hossain, Uddin, M. Sahab, Uddin, G. M. Sala, Sumsuzzman, D. Md, Islam, M. Siddiqul, Barreto, G. E., Bijo Mathew, and Ashraf, G. Md, “Melatonin in Alzheimer's Disease: A Latent Endogenous Regulator of Neurogenesis to Mitigate Alzheimer's Neuropathology.”, Mol Neurobiol, vol. 56, no. 12, pp. 8255-8276, 2019.
Year : 2019
Natural inhibitors on airway mucin: Molecular insight into the therapeutic potential targeting MUC5AC expression and production.
Authors : Dr. Bijo Mathew, Samsuzzaman, Md; Uddin, Md Sahab; Shah, Muhammad Ajmal; Bijo Mathew
Publisher : Life Sci
M. Samsuzzaman, Uddin, M. Sahab, Shah, M. Ajmal, and Bijo Mathew, “Natural inhibitors on airway mucin: Molecular insight into the therapeutic potential targeting MUC5AC expression and production.”, Life Sci, vol. 231, p. 116485, 2019.
Year : 2019
In Vitro Study of the Interaction Between HSA and 4-Bromoindolylchalcone, a Potent Human MAO-B Inhibitor: Spectroscopic and Molecular Modeling Studies
Authors : Dr. Bijo Mathew, Chaves, Otávio Augusto; Sasidharan, Rani; dos Santos de Oliveira, Cosme H. C.; Manju, Sreedharannair Leelabaiamma; Joy, Monu; Bijo Mathew; Netto-Ferreira, José Carlos
Publisher : ChemistrySelect
O. Augusto Chaves, Sasidharan, R., de Oliveira, C. H. C. dos, Manju, S. Leelabaiam, Joy, M., Bijo Mathew, and Netto-Ferreira, J. Carlos, “In Vitro Study of the Interaction Between HSA and 4-Bromoindolylchalcone, a Potent Human MAO-B Inhibitor: Spectroscopic and Molecular Modeling Studies”, ChemistrySelect, vol. 4, pp. 1007-1014, 2019.
Year : 2019
Unraveling the Structural Requirements of Chalcone Chemistry Towards Monoamine Oxidase Inhibition.
Authors : Dr. Bijo Mathew
Publisher : Cent Nerv Syst Agents Med Chem
Year : 2019
Fe O nanoparticles mediated synthesis of novel spirooxindole-dihydropyrimidinone molecules as Hsp90 inhibitors.
Authors : Dr. Bijo Mathew, Maddela, Srinubabu; Makula, Ajitha; Galigniana, Mario D; Parambi, Della G T; Federicci, Fernando; Mazaira, Gisela; Hendawy, Omnia M; Dev, Sanal; Mathew, Githa E; Bijo Mathew
Publisher : Arch Pharm (Weinheim)
S. Maddela, Makula, A., Galigniana, M. D., Parambi, D. G. T., Federicci, F., Mazaira, G., Hendawy, O. M., Dev, S., Mathew, G. E., and Bijo Mathew, “Fe O nanoparticles mediated synthesis of novel spirooxindole-dihydropyrimidinone molecules as Hsp90 inhibitors.”, Arch Pharm (Weinheim), vol. 352, no. 1, p. e1800174, 2019.
Year : 2019
Potent and highly selective dual-targeting monoamine oxidase-B inhibitors: Fluorinated chalcones of morpholine versus imidazole
Authors : Dr. Bijo Mathew, Bijo Mathew; Baek, Seung C; Thomas Parambi, Della G; Lee, Jae P; Mathew, Githa E; Jayanthi, Sivaraman; Vinod, Devaraji; Rapheal, Clariya; Devikrishna, Vinod; Kondarath, Shahin Shad; Uddin, Md Sahab; Kim, Hoon
Publisher : Arch Pharm (Weinheim)
Bijo Mathew, Baek, S. C., Parambi, D. G. Thomas, Lee, J. P., Mathew, G. E., Jayanthi, S., Vinod, D., Rapheal, C., Devikrishna, V., Kondarath, S. Shad, Uddin, M. Sahab, and Kim, H., “Potent and highly selective dual-targeting monoamine oxidase-B inhibitors: Fluorinated chalcones of morpholine versus imidazole.”, Arch Pharm (Weinheim), vol. 352, no. 4, p. e1800309, 2019.
Year : 2019
Silicon Quantum Dots: Promising Theranostic Probes for the Future.
Authors : Dr. Bijo Mathew, Sivasankarapillai, Vishnu Sankar; Jose, Jobin; Shanavas, Muhammad Salman; Marathakam, Akash; Uddin, Md Sahab; Bijo Mathew
Publisher : Curr Drug Targets
V. Sankar Sivasankarapillai, Jose, J., Shanavas, M. Salman, Marathakam, A., Uddin, M. Sahab, and Bijo Mathew, “Silicon Quantum Dots: Promising Theranostic Probes for the Future.”, Curr Drug Targets, vol. 20, no. 12, pp. 1255-1263, 2019.
Year : 2019
Nootropic and Anti-Alzheimer’s Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer’s Neuropathology
Authors : Dr. Bijo Mathew, Uddin, Md Sahab; Al Mamun, Abdullah; Kabir, Md Tanvir; Jakaria, Md; Bijo Mathew; Barreto, George E; Ashraf, Ghulam Md
Publisher : Mol Neurobiol
M. Sahab Uddin, Mamun, A. Al, Kabir, M. Tanvir, Jakaria, M., Bijo Mathew, Barreto, G. E., and Ashraf, G. Md, “Nootropic and Anti-Alzheimer's Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer's Neuropathology.”, Mol Neurobiol, vol. 56, no. 7, pp. 4925-4944, 2019.
Year : 2018
Imidazole bearing chalcones as a new class of monoamine oxidase inhibitors.
Authors : Dr. Bijo Mathew, Sasidharan, Rani; Baek, Seung Cheol; Sreedharannair Leelabaiamma, Manju; Kim, Hoon
Publisher : Biomed Pharmacothe
R. Sasidharan, Baek, S. Cheol, Leelabaiamma, M. Sreedharan, Kim, H., and Bijo Mathew, “Imidazole bearing chalcones as a new class of monoamine oxidase inhibitors.”, Biomed Pharmacother, vol. 106, pp. 8-13, 2018.
Year : 2018
Virtual combinatorial library design, synthesis and in vitro anticancer assessment of -2-amino-3-cyanopyridine derivatives
Authors : Dr. Bijo Mathew, Dev S.; Dhaneshwar SR;
Publisher : Combinatorial Chemistry and High Throughput Screening. [Bentham Science]
D. S., ,, and Bijo Mathew, “Virtual combinatorial library design, synthesis and in vitro anticancer assessment of -2-amino-3-cyanopyridine derivatives”, Combinatorial Chemistry and High Throughput Screening. [Bentham Science], vol. 21, pp. 138-148, 2018.
Year : 2018
Structural and optical profile of a multifunctionalized 2-pyridone derivative in a crystal engineering perspective.
Authors : Dr. Bijo Mathew, Joy, Monu; Anabha, E R; Gopi, Subash; Kumar S, Ajeesh; Mathews, Annie
Publisher : Acta Crystallogr C Struct Chem
M. Joy, Anabha, E. R., Gopi, S., Bijo Mathew, S, A. Kumar, and Mathews, A., “Structural and optical profile of a multifunctionalized 2-pyridone derivative in a crystal engineering perspective.”, Acta Crystallogr C Struct Chem, vol. 74, no. Pt 7, pp. 807-815, 2018.
Year : 2018
Selected aryl thiosemicarbazones as a new class of multi-targeted monoamine oxidase inhibitors.
Authors : Dr. Bijo Mathew, Bijo Mathew; Baek, Seung Cheol; Grace Thomas Parambi, Della; Pil Lee, Jae; Joy, Monu; Annie Rilda, P R; Randev, Rugma V; Nithyamol, P; Vijayan, Vijitha; Inasu, Sini T; Mathew, Githa Elizabeth; Lohidakshan, Krishnakumar K; Kumar Krishnan, Girish; Kim, Hoon
Publisher : Medchemcomm
Bijo Mathew, Baek, S. Cheol, Parambi, D. Grace Thom, Lee, J. Pil, Joy, M., Rilda, P. R. Annie, Randev, R. V., Nithyamol, P., Vijayan, V., Inasu, S. T., Mathew, G. Elizabeth, Lohidakshan, K. K., Krishnan, G. Kumar, and Kim, H., “Selected aryl thiosemicarbazones as a new class of multi-targeted monoamine oxidase inhibitors.”, Medchemcomm, vol. 9, no. 11, pp. 1871-1881, 2018.
Year : 2018
Dual acting Isatin-Heterocyclic Hybrids: Recent Highlights as Promising Pharmacological Agents
Authors : Dr. Bijo Mathew
Publisher : Volume 15
Bijo Mathew, “Dual acting Isatin-Heterocyclic Hybrids: Recent Highlights as Promising Pharmacological Agents”, vol. 15, 2018.
Year : 2018
Discovery of new class of methoxy carrying isoxazole derivatives as COX-II inhibitors: Investigation of a detailed molecular dynamics study
Authors : Dr. Bijo Mathew, Monu Joy; Ahmed A. Elrashedy; Bijo Mathew; Ashona Singh Pillay; Annie Mathews; Sanal Dev; Mahmoud E.S. Soliman; C. Sudarsanakumar
Publisher : Journal of Molecular Structure
M. Joy, Elrashedy, A. A., Bijo Mathew, Pillay, A. Singh, Mathews, A., Dev, S., Soliman, M. E. S., and Sudarsanakumar, C., “Discovery of new class of methoxy carrying isoxazole derivatives as COX-II inhibitors: Investigation of a detailed molecular dynamics study”, Journal of Molecular Structure, vol. 1157, pp. 19-28, 2018.
Year : 2018
Discovery of potent and reversible MAO-B inhibitors as furanochalcones
Authors : Dr. Bijo Mathew, Jerad Suresh; Seung Cheol Baek; Surya Parakkot Ramakrishnan; Hoon Kim
Publisher : International Journal of Biological Macromolecules
J. Suresh, Baek, S. Cheol, Ramakrishnan, S. Parakkot, Kim, H., and Bijo Mathew, “Discovery of potent and reversible MAO-B inhibitors as furanochalcones”, International Journal of Biological Macromolecules, vol. 108, pp. 660-664, 2018.
Year : 2018
Introduction of fluorinated environment on metformin. Evaluation of its serum-albumin interaction with molecular modeling studies
Authors : Dr. Bijo Mathew, Otávio Augusto Chaves; Monu Joy; Krishnakumar K. Lohidakshan; Akash Marathakam; José Carlos Netto-Ferreira
Publisher : Journal of Molecular Liquids
O. Augusto Chaves, Bijo Mathew, Joy, M., Lohidakshan, K. K., Marathakam, A., and Netto-Ferreira, J. Carlos, “Introduction of fluorinated environment on metformin. Evaluation of its serum-albumin interaction with molecular modeling studies”, Journal of Molecular Liquids, vol. 260, pp. 186-194, 2018.
Year : 2018
Structural features of Safinamide: A combined Hirshfeld surface analysis & quantum chemical treatment
Authors : Dr. Bijo Mathew, Monu Joy; Bijo Mathew; C. Sudarsanakumar
Publisher : Chemical Data Collections
M. Joy, Bijo Mathew, and Sudarsanakumar, C., “Structural features of Safinamide: A combined Hirshfeld surface analysis & quantum chemical treatment”, Chemical Data Collections, vol. 17-18, pp. 404-414, 2018.
Year : 2017
Monoamine oxidase inhibitory activity of methoxy-substituted chalcones.
Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Ucar, Gülberk; Joy, Monu; Nafna, E K; Lohidakshan, Krishnakumar K; Suresh, Jerad
Publisher : Int J Biol Macromol
Bijo Mathew, Mathew, G. Elizabeth, Ucar, G., Joy, M., Nafna, E. K., Lohidakshan, K. K., and Suresh, J., “Monoamine oxidase inhibitory activity of methoxy-substituted chalcones.”, Int J Biol Macromol, vol. 104, no. Pt A, pp. 1321-1329, 2017.
Year : 2017
Pharmacophore-Based 3D-QSAR Analysis of Thienyl Chalcones as a New Class of Human MAO-B Inhibitors: Investigation of Combined Quantum Chemical and Molecular Dynamics Approach.
Authors : Dr. Bijo Mathew, Pharma; Adeniyi, Adebayo A; Dev, Sanal; Joy, Monu; Ucar, Gülberk; Mathew, Githa Elizabeth; Singh-Pillay, Ashona; Soliman, Mahmoud E S
Publisher : J Phys Chem B
Bijo Mathew, Adeniyi, A. A., Dev, S., Joy, M., Ucar, G., Mathew, G. Elizabeth, Singh-Pillay, A., and Soliman, M. E. S., “Pharmacophore-Based 3D-QSAR Analysis of Thienyl Chalcones as a New Class of Human MAO-B Inhibitors: Investigation of Combined Quantum Chemical and Molecular Dynamics Approach.”, J Phys Chem B, vol. 121, no. 6, pp. 1186-1203, 2017.
Year : 2017
Molecular modeling of drug-pathophysiological Mtb protein targets: Synthesis of some 2-thioxo-1, 3-thiazolidin-4-one derivatives as anti-tubercular agents
Authors : Dr. Bijo Mathew, K.M. Noorulla; Ayyadurai Jerad Suresh; Vinod Devaraji; Devi Umesh
Publisher : Journal of Molecular Structure
K. M. Noorulla, Suresh, A. Jerad, Devaraji, V., Bijo Mathew, and Umesh, D., “Molecular modeling of drug-pathophysiological Mtb protein targets: Synthesis of some 2-thioxo-1, 3-thiazolidin-4-one derivatives as anti-tubercular agents”, Journal of Molecular Structure, vol. 1147, pp. 682-696, 2017.
Year : 2017
Spectroscopic, zeta potential and molecular docking analysis on the interaction between human serum albumin and halogenated thienyl chalcones
Authors : Dr. Bijo Mathew, Otávio Augusto Chaves; Dari Cesarin-Sobrinho; Balasubramanian Lakshminarayanan; Monu Joy; Githa Elizabeth Mathew; Jerad Suresh; José Carlos Netto-Ferreira
Publisher : Journal of Molecular Liquids
O. Augusto Chaves, Bijo Mathew, Cesarin-Sobrinho, D., Lakshminarayanan, B., Joy, M., Mathew, G. Elizabeth, Suresh, J., and Netto-Ferreira, J. Carlos, “Spectroscopic, zeta potential and molecular docking analysis on the interaction between human serum albumin and halogenated thienyl chalcones”, Journal of Molecular Liquids, vol. 242, pp. 1018-1026, 2017.
Year : 2017
Synthetic Approaches to Various Class of Topoisomerase II Inhibitors
Authors : Dr. Bijo Mathew, Sanal Dev; Nishad Gabhe; S.R. Dhaneshwar; Monu Joy
Publisher : Mini-Reviews in Organic Chemistry
S. Dev, Gabhe, N., Dhaneshwar, S. R., Joy, M., and Bijo Mathew, “Synthetic Approaches to Various Class of Topoisomerase II Inhibitors”, Mini-Reviews in Organic Chemistry, vol. 14, pp. 357-374, 2017.
Year : 2017
Probing mechanism of α-formylketene dithioacetal towards the facile formation of functionalized pyrimidines: A structural approach
Authors : Dr. Bijo Mathew, Monu Joy; Adebayo A. Adeniyi; Annie Mathews; Bijo Mathew; S. Prasanth; Mohmoud E.S. Soliman; Jalaja J. Malayan; E.R. Anabha
Publisher : Journal of Molecular Structure
M. Joy, Adeniyi, A. A., Mathews, A., Bijo Mathew, Prasanth, S., Soliman, M. E. S., Malayan, J. J., and Anabha, E. R., “Probing mechanism of α-formylketene dithioacetal towards the facile formation of functionalized pyrimidines: A structural approach”, Journal of Molecular Structure, vol. 1127, pp. 498-510, 2017.
Year : 2017
Anti-oxidant behavior of functionalized chalcone-a combined quantum chemical and crystallographic structural investigation
Authors : Dr. Bijo Mathew, Adeniyi, Adebayo A.; Joy, Monu; Mathew, Githa Elizabeth; Singh-Pillay, Ashona; Sudarsanakumar, C.; Soliman, Mahmoud E. S.; Suresh, Jerad
Publisher : Journal of Molecular Structure
Bijo Mathew, Adeniyi, A. A., Joy, M., Mathew, G. Elizabeth, Singh-Pillay, A., Sudarsanakumar, C., Soliman, M. E. S., and Suresh, J., “Anti-oxidant behavior of functionalized chalcone-a combined quantum chemical and crystallographic structural investigation”, Journal of Molecular Structure, vol. 1146, pp. 301-308, 2017.
Year : 2017
Characterization of Thienylchalcones as hMAO-B Inhibitors: Synthesis, Biochemistry and Molecular Dynamics Studies
Authors : Dr. Bijo Mathew, Bijo Mathew; Ucar, Gülberk; Rapheal, Clariya; Mathew, Githa E.; Joy, Monu; Machaba, Kgothatso E.; Soliman, Mahmoud E. S.
Publisher : ChemistrySelect, Volume 2
Bijo Mathew, Ucar, G., Rapheal, C., Mathew, G. E., Joy, M., Machaba, K. E., and Soliman, M. E. S., “Characterization of Thienylchalcones as hMAO-B Inhibitors: Synthesis, Biochemistry and Molecular Dynamics Studies”, ChemistrySelect, vol. 2, pp. 11113-11119, 2017.
Year : 2017
Molecular Docking, Synthesis and CNS Activity of Some Novel 1, 4-Benzodiazepine Derivatives
Authors : Dr. Bijo Mathew, Sunil S. Menghani*; Rupesh Chikhale; Amit Pant; Bijo Mathew; Pramod Khedekar
S. S. Menghani*, Chikhale, R., Pant, A., Bijo Mathew, and Khedekar, P., “Molecular Docking, Synthesis and CNS Activity of Some Novel 1, 4-Benzodiazepine Derivatives”, 2017.
Year : 2017
Structural Exploration of Synthetic Chromones as Selective MAO-B Inhibitors: A Mini Review.
Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Petzer, Jacobus P; Petzer, Anel
Publisher : Comb Chem High Throughput Screen
Bijo Mathew, Mathew, G. Elizabeth, Petzer, J. P., and Petzer, A., “Structural Exploration of Synthetic Chromones as Selective MAO-B Inhibitors: A Mini Review.”, Comb Chem High Throughput Screen, vol. 20, no. 6, pp. 522-532, 2017.
Year : 2017
Refining the Structural Features of Chromones as Selective MAO-B Inhibitors: Exploration of Combined Pharmacophore-Based 3D-QSAR and Quantum Chemical Studies
Authors : Dr. Bijo Mathew, Bijo Mathew; Dev, Sanal; Joy, Monu; Mathew, Githa E.; Marathakam, Akash; Krishnan, Girish K.
Publisher : John Wiley & Sons, Ltd
Bijo Mathew, Dev, S., Joy, M., Mathew, G. E., Marathakam, A., and Krishnan, G. K., “Refining the Structural Features of Chromones as Selective MAO-B Inhibitors: Exploration of Combined Pharmacophore-Based 3D-QSAR and Quantum Chemical Studies”, ChemistrySelectChemistrySelectChemistrySelect, vol. 2, no. 35, pp. 11645 - 11652, 2017.
Year : 2016
Monoamine Oxidase Inhibitory Activity: Methyl- versus Chlorochalcone Derivatives.
Authors : Dr. Bijo Mathew, Bijo Mathew; Ucar, Gülberk; Mathew, Githa Elizabeth; Mathew, Sincy; Kalatharakkal Purapurath, Praseedha; Moolayil, Fasil; Mohan, Smrithy; Varghese Gupta, Sheeba
Publisher : ChemMedChem
Bijo Mathew, Ucar, G., Mathew, G. Elizabeth, Mathew, S., Purapurath, P. Kalatharak, Moolayil, F., Mohan, S., and Gupta, S. Varghese, “Monoamine Oxidase Inhibitory Activity: Methyl- versus Chlorochalcone Derivatives.”, ChemMedChem, vol. 11, no. 24, pp. 2649-2655, 2016.
Year : 2016
Synthesis, Biochemistry, and Computational Studies of Brominated Thienyl Chalcones: A New Class of Reversible MAO-B Inhibitors.
Authors : Dr. Bijo Mathew, Haridas, Abitha; Ucar, Gülberk; Baysal, Ipek; Joy, Monu; Mathew, Githa E; Lakshmanan, Baskar; Jayaprakash, Venkatesan
Publisher : ChemMedChem
Bijo Mathew, Haridas, A., Ucar, G., Baysal, I., Joy, M., Mathew, G. E., Lakshmanan, B., and Jayaprakash, V., “Synthesis, Biochemistry, and Computational Studies of Brominated Thienyl Chalcones: A New Class of Reversible MAO-B Inhibitors.”, ChemMedChem, vol. 11, no. 11, pp. 1161-71, 2016.
Year : 2016
Exploration of chlorinated thienyl chalcones: A new class of monoamine oxidase-B inhibitors.
Authors : Dr. Bijo Mathew, Haridas, Abitha; Ucar, Gülberk; Baysal, Ipek; Adeniyi, Adebayo A; Soliman, Mahmoud E S; Joy, Monu; Mathew, Githa Elizabeth; Lakshmanan, Baskar; Jayaprakash, Venkatesan
Publisher : Int J Biol Macromol
Bijo Mathew, Haridas, A., Ucar, G., Baysal, I., Adeniyi, A. A., Soliman, M. E. S., Joy, M., Mathew, G. Elizabeth, Lakshmanan, B., and Jayaprakash, V., “Exploration of chlorinated thienyl chalcones: A new class of monoamine oxidase-B inhibitors.”, Int J Biol Macromol, vol. 91, pp. 680-95, 2016.
Year : 2016
Ligand based drug design of new heterocyclic imines of GABA analogues: A molecular docking approach for the discovery of new GABA-AT inhibitors.
Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Suresh, Jerad; Usman, Dhasthakeer; Shiva Subramanyan, Puthucode Natarajan; Safna, Kallivalappil Fathima
Publisher : Cent Nerv Syst Agents Med Chem
Bijo Mathew, Mathew, G. Elizabeth, Suresh, J., Usman, D., Subramanyan, P. Natarajan, and Safna, K. Fathima, “Ligand based drug design of new heterocyclic imines of GABA analogues: A molecular docking approach for the discovery of new GABA-AT inhibitors.”, Cent Nerv Syst Agents Med Chem, 2016.
Year : 2016
Identification of Indole-Based Chalcones: Discovery of a Potent, Selective, and Reversible Class of MAO-B Inhibitors.
Authors : Dr. Bijo Mathew, Sasidharan, Rani; Manju, Sreedharannair Leelabaiamma; Ucar, Gülberk; Baysal, Ipek
Publisher : Arch Pharm (Weinheim)
R. Sasidharan, Manju, S. Leelabaiam, Ucar, G., Baysal, I., and Bijo Mathew, “Identification of Indole-Based Chalcones: Discovery of a Potent, Selective, and Reversible Class of MAO-B Inhibitors.”, Arch Pharm (Weinheim), vol. 349, no. 8, pp. 627-37, 2016.
Year : 2016
Discovery of Camptothecin Based Topoisomerase I Inhibitors: Identification Using an Atom Based 3D-QSAR, Pharmacophore Modeling, Virtual Screening and Molecular Docking Approach.
Authors : Dr. Bijo Mathew, Dev, Sanal; Dhaneshwar, Sunil R; Bijo Mathew
Publisher : Comb Chem High Throughput Screen
S. Dev, Dhaneshwar, S. R., and Bijo Mathew, “Discovery of Camptothecin Based Topoisomerase I Inhibitors: Identification Using an Atom Based 3D-QSAR, Pharmacophore Modeling, Virtual Screening and Molecular Docking Approach.”, Comb Chem High Throughput Screen, vol. 19, no. 9, pp. 752-763, 2016.
Year : 2016
Development of novel (1-H) benzimidazole bearing pyrimidine-trione based MAO-A inhibitors: Synthesis, docking studies and antidepressant activity
Authors : Dr. Bijo Mathew, Jerad Suresh; S. Anbazhagan
Publisher : Journal of Saudi Chemical Society
Bijo Mathew, Suresh, J., and Anbazhagan, S., “Development of novel (1-H) benzimidazole bearing pyrimidine-trione based MAO-A inhibitors: Synthesis, docking studies and antidepressant activity”, Journal of Saudi Chemical Society, vol. 20, pp. S132-S139, 2016.
Year : 2016
Discovery of some novel imines of 2-amino, 5-thio, 1,3,4-thiadiazole as mucomembranous protector. Synthesis, anti-oxidant activity and in silico PASS approach
Authors : Dr. Bijo Mathew, Jerad Suresh; S. Anbazhagan; N. Chidambaranathan
Publisher : Journal of Saudi Chemical Society
Bijo Mathew, Suresh, J., Anbazhagan, S., and Chidambaranathan, N., “Discovery of some novel imines of 2-amino, 5-thio, 1,3,4-thiadiazole as mucomembranous protector. Synthesis, anti-oxidant activity and in silico PASS approach”, Journal of Saudi Chemical Society, vol. 20, pp. S426-S432, 2016.
Year : 2016
Potent and Selective Monoamine Oxidase-B Inhibitory Activity: Fluoro- vs. Trifluoromethyl-4-hydroxylated Chalcone Derivatives.
Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Ucar, Gülberk; Baysal, Ipek; Suresh, Jerad; Mathew, Sincy; Haridas, Abitha; Jayaprakash, Venkatesan
Publisher : Chem Biodivers
Bijo Mathew, Mathew, G. Elizabeth, Ucar, G., Baysal, I., Suresh, J., Mathew, S., Haridas, A., and Jayaprakash, V., “Potent and Selective Monoamine Oxidase-B Inhibitory Activity: Fluoro- vs. Trifluoromethyl-4-hydroxylated Chalcone Derivatives.”, Chem Biodivers, vol. 13, no. 8, pp. 1046-52, 2016.
Year : 2016
Monoamine Oxidase Inhibitors: Perspective Design for the Treatment of Depression and Neurological Disorders
Authors : Dr. Bijo Mathew, Githa E. Mathew; Jerad Suresh; Gülberk Ucar; Rani Sasidharan; Sockalingam Anbazhagan; Jobin K. Vilapurathu and Venkatesan Jayaprakash
Bijo Mathew, Mathew, G. E., Suresh, J., Ucar, G., Sasidharan, R., Anbazhagan, S., and Jayaprakash, J. K. Vilapur, “Monoamine Oxidase Inhibitors: Perspective Design for the Treatment of Depression and Neurological Disorders”, 2016.
Year : 2016
Molecular Docking Studies of Some Novel Antidepressant 5-Substituted Phenyl-3-(Thiophen-2-yl)-4, 5-Dihydro-1h-Pyrazole-1-Carboxamides Against Monoamine Oxidase Isoforms.
Authors : Dr. Bijo Mathew, Suresh, Jerad; Anbazhagan, Sockalingam; Dev, Sanal
Publisher : Cent Nerv Syst Agents Med Chem
Bijo Mathew, Suresh, J., Anbazhagan, S., and Dev, S., “Molecular Docking Studies of Some Novel Antidepressant 5-Substituted Phenyl-3-(Thiophen-2-yl)-4, 5-Dihydro-1h-Pyrazole-1-Carboxamides Against Monoamine Oxidase Isoforms.”, Cent Nerv Syst Agents Med Chem, vol. 16, no. 2, pp. 75-80, 2016.
Year : 2016
Monoamine Oxidase Inhibitory Action of Chalcones: A Mini Review.
Authors : Dr. Bijo Mathew, Haridas, Abitha; Suresh, Jerad; Mathew, Githa E; Ucar, Gülberk; Jayaprakash, Venkatesan
Publisher : Cent Nerv Syst Agents Med Chem
Bijo Mathew, Haridas, A., Suresh, J., Mathew, G. E., Ucar, G., and Jayaprakash, V., “Monoamine Oxidase Inhibitory Action of Chalcones: A Mini Review.”, Cent Nerv Syst Agents Med Chem, vol. 16, no. 2, pp. 120-36, 2016.
Year : 2016
Pharmacophore Modeling, 3D-QSAR and Molecular Docking of Furanochalcones as Inhibitors of Monoamine Oxidase-B.
Authors : Dr. Bijo Mathew, Dev, Sanal; Suresh, Jerad; Mathew, Githa E; Lakshmanan, Baskar; Haridas, Abitha; Fathima, Fajeelath; Krishnan, Girish K
Publisher : Cent Nerv Syst Agents Med Chem
Bijo Mathew, Dev, S., Suresh, J., Mathew, G. E., Lakshmanan, B., Haridas, A., Fathima, F., and Krishnan, G. K., “Pharmacophore Modeling, 3D-QSAR and Molecular Docking of Furanochalcones as Inhibitors of Monoamine Oxidase-B.”, Cent Nerv Syst Agents Med Chem, vol. 16, no. 2, pp. 105-11, 2016.
Year : 2016
Synthesis, ADME studies, toxicity estimation, and exploration of molecular recognition of thiophene based chalcones towards monoamine oxidase-A and B
Authors : Dr. Bijo Mathew, Bijo Mathew; Suresh, Jerad; Elizabeth Mathew, Githa; Haridas, Abitha; Suresh, Geethu; Sabreena, P.
Publisher : Volume 5, Issue 4, p.396 - 401 (2016)
Bijo Mathew, Suresh, J., Mathew, G. Elizabeth, Haridas, A., Suresh, G., and Sabreena, P., “Synthesis, ADME studies, toxicity estimation, and exploration of molecular recognition of thiophene based chalcones towards monoamine oxidase-A and B”, vol. 5, no. 4, pp. 396 - 401, 2016.
Year : 2015
Development of Fluorinated Thienylchalcones as Monoamine Oxidase-B Inhibitors: Design, Synthesis, Biological Evaluation and Molecular Docking Studies
Authors : Dr. Bijo Mathew, Gülberk Ucar; Samiye Yabanogclu-Ciftci; Ipek Baysal; Jerad Suresh; Githa Elizabeth Mathew; Jobin Kunjumon Vilapurathu; A. M. Nadeena; P. Nabeela; V. Lakshmi; Abitha Haridas and Fajeelath Fathima
Bijo Mathew, Ucar, G., Yabanogclu-Ciftci, S., Baysal, I., Suresh, J., Mathew, G. Elizabeth, Vilapurathu, J. Kunjumon, Nadeena, A. M., Nabeela, P., Lakshmi, V., and Fathima, A. Haridas an, “Development of Fluorinated Thienylchalcones as Monoamine Oxidase-B Inhibitors: Design, Synthesis, Biological Evaluation and Molecular Docking Studies”, 2015.
Year : 2015
Psychomotor Seizure Screening and in vitro Neuroprotection Assay of Hydrazones Derived from 2-Acetyl Thiophene.
Authors : Dr. Bijo Mathew, Bijo Mathew; Mathew, Githa E; Suresh, Jerad; Jaseel, Mohammed; Usman, D; Shiva Subramanyan, P N; Safna, Kallivalappil F; Vilapurathu, Jobin K
Publisher : Cent Nerv Syst Agents Med Chem
Bijo Mathew, Mathew, G. E., Suresh, J., Jaseel, M., Usman, D., Subramanyan, P. N. Shiva, Safna, K. F., and Vilapurathu, J. K., “Psychomotor Seizure Screening and in vitro Neuroprotection Assay of Hydrazones Derived from 2-Acetyl Thiophene.”, Cent Nerv Syst Agents Med Chem, 2015.
Year : 2015
Determination of in vitro free radical scavenging and antiproliferative effect of Pennisetum alopecuroides on cultured A549 human lung cancer cells.
Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Bijo Mathew; Gokul, S; Krishna, Rahul; Farisa, M P
Publisher : Anc Sci Life
G. Elizabeth Mathew, Bijo Mathew, Gokul, S., Krishna, R., and Farisa, M. P., “Determination of in vitro free radical scavenging and antiproliferative effect of Pennisetum alopecuroides on cultured A549 human lung cancer cells.”, Anc Sci Life, vol. 34, no. 3, pp. 175-8, 2015.
Year : 2015
Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies.
Authors : Dr. Bijo Mathew, Mathew, Githa Elizabeth; Ucar, Gülberk; Baysal, Ipek; Suresh, Jerad; Vilapurathu, Jobin Kunjumon; Prakasan, Aneesh; Suresh, Jeethu Kuruppath; Thomas, Anjana
Publisher : Bioorg Chem
Bijo Mathew, Mathew, G. Elizabeth, Ucar, G., Baysal, I., Suresh, J., Vilapurathu, J. Kunjumon, Prakasan, A., Suresh, J. Kuruppath, and Thomas, A., “Development of fluorinated methoxylated chalcones as selective monoamine oxidase-B inhibitors: Synthesis, biochemistry and molecular docking studies.”, Bioorg Chem, vol. 62, pp. 22-9, 2015.
Year : 2015
Flavonoids: An Outstanding Structural Core for the Inhibition of Xanthine Oxidase Enzyme
Authors : Dr. Bijo Mathew, Jerad Suresh; Githa E. Mathew; Sherin A. Rasheed; Jobin K. Vilapurathu and P. Jayaraj
Bijo Mathew, Suresh, J., Mathew, G. E., Rasheed, S. A., and Jayaraj, J. K. Vilapur, “Flavonoids: An Outstanding Structural Core for the Inhibition of Xanthine Oxidase Enzyme”, 2015.
Year : 2015
Molecular Hybridization and Preclinical Evaluation of Imines From Para-substituted 4-phenyl 2-amino Thiazole Incorporated with Isatin Analogues as Antitubercular Agents
Authors : Dr. Bijo Mathew, Nice Joy
Publisher : Anti-Infective Agents
N. Joy and Bijo Mathew, “Molecular Hybridization and Preclinical Evaluation of Imines From Para-substituted 4-phenyl 2-amino Thiazole Incorporated with Isatin Analogues as Antitubercular Agents”, Anti-Infective Agents, 13 vol., no. 1, 2015.
Year : 2015
Hydrazones as a privileged structural linker in antitubercular agents: a review.
Authors : Dr. Bijo Mathew, Suresh, Jerad; Ahsan, Mohamed J; Mathew, Githa E; Usman, Dhasthakeer; Subramanyan, Puthucode N S; Safna, Kallivalappil F; Maddela, Srinubabu
Publisher : Infect Disord Drug Targets
Bijo Mathew, Suresh, J., Ahsan, M. J., Mathew, G. E., Usman, D., Subramanyan, P. N. S., Safna, K. F., and Maddela, S., “Hydrazones as a privileged structural linker in antitubercular agents: a review.”, Infect Disord Drug Targets, vol. 15, no. 2, pp. 76-88, 2015.
Year : 2014
Molecular Recognisation of 3a, 4-Dihydro-3-H-Indeno [1, 2-C] Pyrazole-2- Carboxamide/Carbothioamide Anticonvulsant Analogues Towards GABA-Aminotransferase- An in Silico Approach
Authors : Dr. Bijo Mathew, Ahsan, Mohamed
Publisher : Central Nervous System Agents in Medicinal Chemistry
Bijo Mathew and Ahsan, M., “Molecular Recognisation of 3a, 4-Dihydro-3-H-Indeno [1, 2-C] Pyrazole-2- Carboxamide/Carbothioamide Anticonvulsant Analogues Towards GABA-Aminotransferase- An in Silico Approach”, Central Nervous System Agents in Medicinal Chemistry, vol. 14, 2014.
Year : 2014
Isolation of chemical constituents from Spilanthes calva DC: Toxicity, anthelmintic efficacy and in silico studies
Authors : Dr. Bijo Mathew, P. Jayaraj; C. Mani; R. Govindarajan
Publisher : Biomedicine & Preventive Nutrition
P. Jayaraj, Bijo Mathew, Mani, C., and Govindarajan, R., “Isolation of chemical constituents from Spilanthes calva DC: Toxicity, anthelmintic efficacy and in silico studies”, Biomedicine & Preventive Nutrition, vol. 4, pp. 417-423, 2014.
Year : 2014
Synthesis, preclinical evaluation and antidepressant activity of 5-substituted phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides.
Authors : Dr. Bijo Mathew, Suresh, Jerad; Anbazhagan, S
Publisher : EXCLI J
Bijo Mathew, Suresh, J., and Anbazhagan, S., “Synthesis, preclinical evaluation and antidepressant activity of 5-substituted phenyl-3-(thiophen-2-yl)-4, 5-dihydro-1H-pyrazole-1-carbothioamides.”, EXCLI J, vol. 13, pp. 437-45, 2014.
Year : 2014
Design, Synthesis, Toxicity Estimation and Molecular Docking Studies of N-(furan-2-yl)-1-(5-substituted) phenyl-1,3,4-oxadiazol-2-yl) methanimine as Antitubercular Agents.
Authors : Dr. Bijo Mathew, Suresh, J; Mathew, Githa E; Sonia, George; Krishnan, G K
Publisher : Indian J Pharm Sci
Bijo Mathew, Suresh, J., Mathew, G. E., Sonia, G., and Krishnan, G. K., “Design, Synthesis, Toxicity Estimation and Molecular Docking Studies of N-(furan-2-yl)-1-(5-substituted) phenyl-1,3,4-oxadiazol-2-yl) methanimine as Antitubercular Agents.”, Indian J Pharm Sci, vol. 76, no. 5, pp. 401-6, 2014.
Year : 2014
Proposed interaction of some novel antidepressant pyrazolines against monoamine oxidase isoforms. Molecular docking studies and PASS assisted in silico approach
Authors : Dr. Bijo Mathew, Jerad Suresh; S. Anbazhagan; Sanal Dev
Publisher : Biomedicine & Aging Pathology
Bijo Mathew, Suresh, J., Anbazhagan, S., and Dev, S., “Proposed interaction of some novel antidepressant pyrazolines against monoamine oxidase isoforms. Molecular docking studies and PASS assisted in silico approach”, Biomedicine & Aging Pathology, vol. 4, pp. 297-301, 2014.
Year : 2014
Plant secondary metabolites- potent inhibitors of monoamine oxidase isoforms.
Authors : Dr. Bijo Mathew, Bijo Mathew; Suresh, Jerad; Mathew, Githa E; Parasuraman, Ramamoorthy; Abdulla, Nalakathu
Publisher : Cent Nerv Syst Agents Med Chem
Bijo Mathew, Suresh, J., Mathew, G. E., Parasuraman, R., and Abdulla, N., “Plant secondary metabolites- potent inhibitors of monoamine oxidase isoforms.”, Cent Nerv Syst Agents Med Chem, vol. 14, no. 1, pp. 28-33, 2014.
Year : 2014
Isolation and molecular recognization of 6-prenyl apigenin towards MAO-A as the active principle of seeds of Achyranthes aspera
Authors : Dr. Bijo Mathew, Shoban Janet Beula; V. Bhaskar Anada Raj
Publisher : Biomedicine & Preventive Nutrition
S. Janet Beula, V. Raj, B. Anada, and Bijo Mathew, “Isolation and molecular recognization of 6-prenyl apigenin towards MAO-A as the active principle of seeds of Achyranthes aspera”, Biomedicine & Preventive Nutrition, vol. 4, pp. 379-382, 2014.
Year : 2014
Synthesis, in silico preclinical evaluation, antidepressant potential of 5-substituted phenyl-3-(thiophen-2-yl)-4,5-dihydro-1h-pyrazole-1-carboxamides
Authors : Dr. Bijo Mathew, Jerad Suresh; S. Anbazhagan
Publisher : Biomedicine & Aging Pathology
Bijo Mathew, Suresh, J., and Anbazhagan, S., “Synthesis, in silico preclinical evaluation, antidepressant potential of 5-substituted phenyl-3-(thiophen-2-yl)-4,5-dihydro-1h-pyrazole-1-carboxamides”, Biomedicine & Aging Pathology, vol. 4, pp. 327-333, 2014.
Year : 2014
Isolation of a bioactive flavonoid from Spilanthes calva D.C. in vitro xanthine oxidase assay and in silico study
Authors : Dr. Bijo Mathew, P. Jayaraj; Bijo Mathew; B. Parimaladevi; V. Alex Ramani; R. Govindarajan
Publisher : Biomedicine & Preventive Nutrition
P. Jayaraj, Bijo Mathew, Parimaladevi, B., V. Ramani, A., and Govindarajan, R., “Isolation of a bioactive flavonoid from Spilanthes calva D.C. in vitro xanthine oxidase assay and in silico study”, Biomedicine & Preventive Nutrition, vol. 4, pp. 481-484, 2014.
Year : 2014
Heteroaryl chalcones: Mini review about their therapeutic voyage
Authors : Dr. Bijo Mathew, Jerad Suresh; Sockalingam Anbazghagan; Jayaraj Paulraj; Girish K. Krishnan
Publisher : Biomedicine & Preventive Nutrition
Bijo Mathew, Suresh, J., Anbazghagan, S., Paulraj, J., and Krishnan, G. K., “Heteroaryl chalcones: Mini review about their therapeutic voyage”, Biomedicine & Preventive Nutrition, vol. 4, pp. 451-458, 2014.
Year : 2013
Synthesis and in silico design of some novel imines of 5- amino-1,3,4-thiadiazole-2-thiol linked to (1h-benzimidazole-2-yl) 3-substituted phenyl prop-2-enes
Authors : Dr. Bijo Mathew, Suresh, J., and Anbazhagan, S.
Publisher : Indian. J. Heterocycl. Chem
Bijo Mathew, Suresh, J., and Anbazhagan, S., “Synthesis and in silico design of some novel imines of 5- amino-1,3,4-thiadiazole-2-thiol linked to (1h-benzimidazole-2-yl) 3-substituted phenyl prop-2-enes”, Indian. J. Heterocycl. Chem, vol. 22, pp. 337-340, 2013.
Year : 2013
Pyrazoline: a promising scaffold for the inhibition of monoamine oxidase.
Authors : Dr. Bijo Mathew, Suresh, Jerad; Anbazhagan, Sockalingam; Mathew, Githa Elizabeth
Publisher : Cent Nerv Syst Agents Med Chem
Bijo Mathew, Suresh, J., Anbazhagan, S., and Mathew, G. Elizabeth, “Pyrazoline: a promising scaffold for the inhibition of monoamine oxidase.”, Cent Nerv Syst Agents Med Chem, vol. 13, no. 3, pp. 195-206, 2013.
Year : 2013
Antitumour activity of 5-[(2E)-1-(1H-benzimidazol-2-yl)-3-substituted phenylprop-2-en-1-ylidene] pyrimidine-2,4,6(1H,3H,5H)-triones against Dalton’s ascitic lymphoma in mice
Authors : Dr. Bijo Mathew, Suresh, Jerad; Vinod, Devaraji
Publisher : Medicinal Chemistry Research
Bijo Mathew, Suresh, J., and Vinod, D., “Antitumour activity of 5-[(2E)-1-(1H-benzimidazol-2-yl)-3-substituted phenylprop-2-en-1-ylidene] pyrimidine-2,4,6(1H,3H,5H)-triones against Dalton’s ascitic lymphoma in mice”, Medicinal Chemistry Research, vol. 22, no. 8, pp. 3911 - 3917, 2013.
Year : 2013
Design of 1-(furan-2-yl)-N-(5-substituted phenyl-1, 3, 4-thiadiazol-2-yl) methanimine derivatives as Enoyl-ACP reductase inhibitors: Synthesis, molecular docking studies and anti-tubercular activity
Authors : Dr. Bijo Mathew, Mathew, Githa; Sonia, George; Kumar, Anila; Charles, Neethu; Kumar, Palanisamy
Publisher : Bangladesh Journal of Pharmacology
Bijo Mathew, Mathew, G., Sonia, G., Kumar, A., Charles, N., and Kumar, P., “Design of 1-(furan-2-yl)-N-(5-substituted phenyl-1, 3, 4-thiadiazol-2-yl) methanimine derivatives as Enoyl-ACP reductase inhibitors: Synthesis, molecular docking studies and anti-tubercular activity”, Bangladesh Journal of Pharmacology, vol. 8, 2013.
Year : 2013
Hypnotic profile of imines from benzimidazole chalcones: mechanism of synthesis, DFT studies and in silico screening.
Authors : Dr. Bijo Mathew, Suresh, Jerad; Anbazhagan, Sockalingam; Devaraji, Vinod
Publisher : Cent Nerv Syst Agents Med Chem
Bijo Mathew, Suresh, J., Anbazhagan, S., and Devaraji, V., “Hypnotic profile of imines from benzimidazole chalcones: mechanism of synthesis, DFT studies and in silico screening.”, Cent Nerv Syst Agents Med Chem, vol. 13, no. 3, pp. 207-16, 2013.
Year : 2013
Synthesis and PASS-assisted in silico approach of some novel 2-substituted benzimidazole bearing a pyrimidine-2, 4, 6(trione) system as mucomembranous protector.
Authors : Dr. Bijo Mathew, Suresh, Jerad; Anbazhagan, Socklingam
Publisher : J Pharm Bioallied Sci
Bijo Mathew, Suresh, J., and Anbazhagan, S., “Synthesis and PASS-assisted in silico approach of some novel 2-substituted benzimidazole bearing a pyrimidine-2, 4, 6(trione) system as mucomembranous protector.”, J Pharm Bioallied Sci, vol. 5, no. 1, pp. 39-43, 2013.
Year : 2012
A Green route approach of α, β unsaturated ketone having a benzimidazole tail and their virtual screening on the molecular descriptors for predicting the CNS-drug likeness
Authors : Dr. Bijo Mathew, Bijo Mathew; Githa Elizebeth Mathew; Shafeer V.P.,; Mohammed Musthafa C.; Femina P.
Publisher : Asian J. Research Chem
Bijo Mathew, Mathew, G. Elizebeth, ,, C., M. Musthafa, and P., F., “A Green route approach of α, β unsaturated ketone having a benzimidazole tail and their virtual screening on the molecular descriptors for predicting the CNS-drug likeness”, Asian J. Research Chem., vol. 5, no. 1, pp. 65-68, 2012.
Year : 2012
Isolation, in silico design and anti-inflammatory activity of spirosolenol from the roots of Solanum anguvi
Authors : Dr. Bijo Mathew, Mathew, G.E.; George, S.; Shamnas, M.; Raj, V.B.A.
Publisher : Chemical Sciences Journal
Bijo Mathew, Mathew, G. E., George, S., Shamnas, M., and Raj, V. B. A., “Isolation, in silico design and anti-inflammatory activity of spirosolenol from the roots of Solanum anguvi”, Chemical Sciences Journal, 2012.
Year : 2012
Microwave Assisted Synthesis, Physico-chemical Properties and Antioxidant Activity of alpha,beta-Unsaturated Benzimidazole Derivatives Incorporated with Baritone Moiety
Authors : Dr. Bijo Mathew, Suresh, Jerad; Anbazhagan, Sockalingam
Publisher : ASIAN JOURNAL OF CHEMISTRY,
Bijo Mathew, Suresh, J., and Anbazhagan, S., “Microwave Assisted Synthesis, Physico-chemical Properties and Antioxidant Activity of alpha,beta-Unsaturated Benzimidazole Derivatives Incorporated with Baritone Moiety”, ASIAN JOURNAL OF CHEMISTRY, vol. 25, pp. 1853-1856, 2012.
Year : 2011
Synthesis of some thiazolidinone derivatives from indole-2 carboxylic acid and evaluation of its xanthine oxidase inhibitory and antioxidant activity
Authors : Dr. Bijo Mathew, Bhuvna C; Mathew B.; Mahalakshmi A.; Sukumar M.
Publisher : International Journal of ChemTech Research
B. C, B., M., A., M., and M., S., “Synthesis of some thiazolidinone derivatives from indole-2 carboxylic acid and evaluation of its xanthine oxidase inhibitory and antioxidant activity”, International Journal of ChemTech Research, vol. 3, no. 2, pp. 671-675, 2011.
Year : 2011
Diuretic activity of leaves of garcinia cambogia in rats.
Authors : Dr. Bijo Mathew, Mathew, Githa E; Shaneeb, M M; Nyanthara, B
Publisher : Indian J Pharm Sci
G. E. Mathew, Bijo Mathew, Shaneeb, M. M., and Nyanthara, B., “Diuretic activity of leaves of garcinia cambogia in rats.”, Indian J Pharm Sci, vol. 73, no. 2, pp. 228-30, 2011.
Year : 2011
Phytochemical evaluation and lipid lowering property of leaves of Vitex negun- do linn. in hyper cholestremic rats
Authors : Dr. Bijo Mathew, Githa, Elizabeth, Mathew
Publisher : IJPSRR
E. Githa, Mathew,, and Bijo Mathew, “Phytochemical evaluation and lipid lowering property of leaves of Vitex negun- do linn. in hyper cholestremic rats”, IJPSRR, vol. 2, 2011.
Year : 2011
Synthesis, characterization and antimicrobial screening of some 2-amino, 5(phenyl substituted) 1, 3, 4-thiadiazole derivatives
Authors : Dr. Bijo Mathew, AJ, J., GE, M., S, S., and SS, K.
Publisher : International Journal of ChemTech Research
Bijo Mathew, AJ, J., GE, M., S, S., and SS, K., “Synthesis, characterization and antimicrobial screening of some 2-amino, 5(phenyl substituted) 1, 3, 4-thiadiazole derivatives”, International Journal of ChemTech Research, vol. 1, no. 3, pp. 364-368, 2011.
Year : 2011
Anthelmintic activity of leaves of garcinia cambogia
Authors : Dr. Bijo Mathew, Mathew, G.E.; Sheneeb, M.; Nyanthara, N.; Haribabu, Y.
Publisher : International Journal of Research in Pharmaceutical Sciences
G. E. Mathew, Bijo Mathew, Sheneeb, M., Nyanthara, N., and Haribabu, Y., “Anthelmintic activity of leaves of garcinia cambogia”, International Journal of Research in Pharmaceutical Sciences, vol. 2, pp. 63-65, 2011.
Year : 2010
Synthesis, molecular properties and anthelmintic activity of some schiff bases of 1, 3, 4 thiadiazole derivatives
Authors : Dr. Bijo Mathew, Vakketh, S.S.; Kumar, S.S.
Publisher : Der pharma chemica
B. Mathew, Vakketh, S. S., and Kumar, S. S., “Synthesis, molecular properties and anthelmintic activity of some schiff bases of 1, 3, 4 thiadiazole derivatives”, Der pharma chemica, vol. 2, pp. 337-343, 2010.
Year : 2010
Synthesis, Characterisation of some 2-azetidinone derivatives from 2-aminopyridine and evaluation of their antimicrobial activity
Authors : Dr. Bijo Mathew, Githa Elizebeth Mathew; Nirmal Mathew; M. Vijayabaskaran
Publisher : Der Pharma Chemica
Bijo Mathew, Mathew, G. Elizebeth, Mathew, N., and Vijayabaskaran, M., “Synthesis, Characterisation of some 2-azetidinone derivatives from 2-aminopyridine and evaluation of their antimicrobial activity”, Der Pharma Chemica, vol. 2, no. 6, pp. 238-242, 2010.
Year : 2010
Phytochemical evaluation and anticancer screening of rhizomes of Kaempferia galanga
Authors : Dr. Bijo Mathew, M, V., GE, M., and KM, T.
Publisher : InternationalResearch Journal of Pharmaceutical Sciences
Bijo Mathew, M, V., GE, M., and KM, T., “Phytochemical evaluation and anticancer screening of rhizomes of Kaempferia galanga”, InternationalResearch Journal of Pharmaceutical Sciences, vol. 1, no. 1, pp. 11-15, 2010.