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Dr. (Maj) Arun K. Valsan

Assistant Professor, Department of Gastroenterology, School of Medicine, Kochi

Qualification: MBBS, MD (Internal Medicine),  DNB (Internal Medicine),  MNAMS,  DM (Hepatology), MRCP(UK)
ResearchGate Profile

Bio

Dr. (Maj) Arun K. Valsan is a Assistant Professor and Consultant Hepatologist and Transplant Physician at Amrita School of Medicine, Kochi. With a distinguished background in hepatology and a strong foundation in internal medicine, Dr. Arun Valsan brings extensive expertise in managing complex liver conditions, including acute-on-chronic liver failure (ACLF), portal hypertension, and transplant hepatology. His military service has further enriched his clinical experience, allowing him to handle critical care situations with precision and care. He is also actively involved in research and has received numerous awards and honors for his contributions to the field of hepatology.

Languages Known

  • English, Malayalam, Hindi and Marathi
Publications

Journal Article

Year : 2024

Choosing the right statistical test: A guide for data analysis

Cite this Research Publication : Ajee KL, Valsan AK, Sankaran R., "Choosing the right statistical test: A guide for data analysis," Amrita Journal of Medicine, 20(2):86-88, April-June 2024. DOI: 10.4103/AMJM.AMJM_27_24.

Publisher : Amrita Journal of Medicine

Year : 2024

A novel proteomic approach for diagnosing and treating infections in acute decompensation of cirrhosis

Cite this Research Publication : Garg P, Verma N, Valsan AK, Sarohi V, Basak T, Ralmilay S, Kaur P, Singh S, De A, Premkumar M, Taneja S., "A novel proteomic approach for diagnosing and treating infections in acute decompensation of cirrhosis," Journal of Clinical and Experimental Hepatology, 2024 Jan 1;14. DOI:10.1016/j.jceh.2024.101945

Publisher : Journal of Clinical and Experimental Hepatology

Year : 2024

A placebo controlled, randomized, double blinded trial to evaluate the use of Tolvaptan for correction of hyponatremia in liver cirrhosis patients (SCOTcH trial)

Cite this Research Publication : Valsan A, Mohamed Z, Malayil G, Paul A, Sudhindran S, Verma N, Unnikrishnan G, Koshy A, Balakrishnan D, Kumar L, Madathil S., "A placebo controlled, randomized, double blinded trial to evaluate the use of Tolvaptan for correction of hyponatremia in liver cirrhosis patients (SCOTcH trial)," Journal of Clinical and Experimental Hepatology, Volume 14, 1019442024 Jan 1, 2024.

Publisher : Journal of Clinical and Experimental Hepatology

Year : 2024

FRI-231 Compared to complete abstainers, non-significant alcohol use may be associated with more severe liver disease in patients with metabolic dysfunction-associated steatotic liver disease (MASLD)-The multicentre study of the indian consortium on MASLD

Cite this Research Publication : Duseja AK, Mehta M, De A, Singh SP, Mukewar S, Mukewar S, Shalimar S, Goyal O, Venkataraman J, Dixit VK, Valsan A, Devadas K., "FRI-231 Compared to complete abstainers, non-significant alcohol use may be associated with more severe liver disease in patients with metabolic dysfunction-associated steatotic liver disease (MASLD)-The multicentre study of the Indian consortium on MASLD," Journal of Hepatology, 2024 Jun 1;80:S475-6. DOI:10.1016/S0168-8278(24)01462-4

Publisher : Journal of Hepatology

Year : 2024

A Short Review on Obeticholic Acid: An Effective Modulator of Farnesoid X Receptor

Cite this Research Publication : Narayanan AK, Surendran S, Balakrishnan D, Gopalakrishnan U, Malick S, Valsan A, Philips CA, Watson CJ. "A Short Review on Obeticholic Acid: An Effective Modulator of Farnesoid X Receptor," Current Reviews in Clinical and Experimental Pharmacology Formerly Current Clinical Pharmacology, 2024 Aug 1; Volume 19, Issue 3, pp: 225-33. DOI: 10.2174/0127724328239536230919070001

Publisher : Current Reviews in Clinical and Experimental Pharmacology

Year : 2024

LBO-004 Excess waitlist mortality and survival benefit of liver transplantation for patients with severe acute-on-chronic liver failure: Interim results of the CHANCE study

Cite this Research Publication : Gustot T, Bernal W, Fernández J, Diaz JM, de la Peña-Ramirez C, Farias A, Zitelli PM, Kuo A, Nissen N, Marciano S, Valsan A, Gadano A., "LBO-004 Excess waitlist mortality and survival benefit of liver transplantation for patients with severe acute-on-chronic liver failure: Interim results of the CHANCE study," Journal of Hepatology, 2024 Jun 1;80:S9-10. DOI:10.1016/S0168-8278(24)00439-2

Publisher : Journal of Hepatology

Year : 2024

LBP-026 The global prospective observational study to evaluate the role of ‘liver transplantation in patients with cirrhosis and severe acute-on-chronic liver failure (CHANCE)’: study design, demographics and overall outcome

Cite this Research Publication : Gustot T, Bernal W, Fernández J, Diaz JM, de la Peña-Ramirez C, Farias A, Zitelli PM, Kuo A, Nissen N, Marciano S, Valsan A, Gadano A., "LBP-026 The global prospective observational study to evaluate the role of ‘liver transplantation in patients with cirrhosis and severe acute-on-chronic liver failure (CHANCE)’: study design, demographics and overall outcome," Journal of Hepatology, 2024 Jun 1;80:S89-91. DOI:10.1016/S0168-8278(24)00593-2

Publisher : Journal of Hepatology

Year : 2024

Performance of spleen stiffness measurement to rule out high-risk varices in patients with porto-sinusoidal vascular disorder

Cite this Research Publication : Moga L, Paradis V, Valsan A, Macedo G, Plessier A, Rautou PE; ERN RARE-LIVER; a study of VALDIG, an EASL consortium, "Performance of spleen stiffness measurement to rule out high-risk varices in patients with porto-sinusoidal vascular disorder," Hepatology, 2024 Jul 2. doi: 10.1097/HEP.0000000000001004. Epub Ahead of print. PMID: 38954825.

Publisher : Hepatology

Year : 2024

Co-relation of Portal Vein Tumour Thrombus Response With Survival Function Following Robotic Radiosurgery in Vascular Invasive Hepatocellular Carcinoma

Cite this Research Publication : Debnarayan Dutta, Sreenija Yarlagadda, Sruthi Kalavagunta, Haridas Nair, Ajay Sasidharan, Sathish Kumar Nimmya, Rajesh Kannan, Shibu George, Annex Edappattu, Nikhil K. Haridas, Wesley M. Jose, Pavithran Keechilat, Arun Valsan, Anoop Koshy, Rajesh Gopalakrishna, Shine Sadasivan, Unnikrishnan Gopalakrishnan, Dinesh Balakrishnan, Othiyil Vayoth Sudheer, Sudhindran Surendran, "Co-relation of portal vein tumour thrombus response with survival function following Robotic Radiosurgery in vascular invasive hepatocellular carcinoma", Journal of Clinical and Experimental Hepatology, Volume 14, Issue 5, September–October 2024, 101404, DOI:10.1016/j.jceh.2024.101404

Publisher : Journal of Clinical and Experimental Hepatology

Year : 2023

Burden, risk factors, and outcomes of multidrug-resistant bacterial colonisation at multiple sites in patients with cirrhosis

Cite this Research Publication : Verma N, Reddy PV, Vig S, Angrup A, Biswal M, Valsan A, Garg P, Kaur P, Rathi S, De A, Premkumar M., "Burden, risk factors, and outcomes of multidrug-resistant bacterial colonisation at multiple sites in patients with cirrhosis," JHEP Reports, 2023 Aug 1;5(8):100788. doi: 10.1016/j.jhepr.2023.100788

Publisher : JHEP Reports

Year : 2023

Ashwagandha-induced liver injury—A case series from India and literature review

Cite this Research Publication : Philips CA, Valsan A, Theruvath AH, Ravindran R, Oommen TT, Rajesh S, Bishnu S, Augustine P. "Ashwagandha-induced liver injury—A case series from India and literature review," Hepatology Communications, 2023 Oct 1;7(10):e0270. DOI: 10.1097/HC9.0000000000000270

Publisher : Hepatology Communications

Year : 2023

Sample size calculation

Cite this Research Publication : Saraswathy S, Anila KN, Sudhindran S, Valsan AK. "Sample size calculation," Amrita Journal of Medicine, 19(4):215-216, October-December 2023. DOI: 10.4103/AMJM.AMJM_81_23.

Publisher : Amrita Journal of Medicine

Year : 2022

A Pragmatic Randomized Trial Comparing the Efficacy of Early Empiric Versus Pre-Emptive Antifungal Therapy in acute-on-Chronic Liver Failure Patients with Suspected Invasive Fungal Infections: An Interim Analysis (Pep-ACLF)

Cite this Research Publication : A Valsan, N Verma, N Shafiq, A Chakrabarti et al., "A Pragmatic Randomized Trial Comparing the Efficacy of Early Empiric Versus Pre-Emptive Antifungal Therapy in acute-on-Chronic Liver Failure Patients with Suspected Invasive Fungal Infections: An Interim Analysis (Pep-ACLF)," Journal of Clinical and Experimental Hepatology, 2022

Publisher : Journal of Clinical and Experimental Hepatology

Year : 2022

An Unusual Presentation of Filariasis as Pyrexia of Unknown Origin

Cite this Research Publication : Hakeem SC, Valsan A, Srivatsa N, Shrutiraaj KA, Khajuria SP, Mohan NK, Kohli K., "An unusual presentation of filariasis as pyrexia of unknown origin: Case report," Amrita Journal of Medicine, 2022 Jul 1;18(3):100.

Publisher : Amrita Journal of Medicine

Year : 2022

P305 Cirrhosis and fungal infections-a cocktail for catastrophe: a systematic review and meta-analysis with machine learning

Cite this Research Publication : Verma N, Singh S, Roy A, Valsan A, Garg P, Pradhan P, Chakrabarti A, Singh M., "P305 Cirrhosis and fungal infections-a cocktail for catastrophe: a systematic review and meta-analysis with machine learning," Medical Mycology, 2022 Sep; 60 (Supplement_1): myac072P305 DOI: https://doi.org/10.1093/mmy/myac072.P305

Publisher : Medical Mycology

Year : 2022

Cirrhosis and fungal infections-a cocktail for catastrophe: A systematic review and meta-analysis with machine learning

Cite this Research Publication : Verma N, Singh S, Roy A, Valsan A, Garg P, Pradhan P, Chakrabarti A, Singh M., "Cirrhosis and fungal infections-a cocktail for catastrophe: A systematic review and meta-analysis with machine learning," Mycoses, 2022 Sep;65(9):844-58.

Publisher : Mycoses

Year : 2020

Serum Transferrin Is an Independent Predictor of Mortality in Severe Alcoholic Hepatitis: Upping the Game or Just Upping the Ante?

Cite this Research Publication : Sainath, Kedhara G., Vasan, Arun, Singh, Virendra, "Serum Transferrin Is an Independent Predictor of Mortality in Severe Alcoholic Hepatitis: Upping the Game or Just Upping the Ante?" American Journal of Gastroenterology, 2020;115:1136. https://doi.org/10.14309/ajg.0000000000000657.

Publisher : American Journal of Gastroenterology

Year : 2020

Albumin: The Hepatologist’s enduring ally demystified?

Cite this Research Publication : Arun Valsan, Akash Roy, Nipun Verma, Arka De, Shivani Chandel, Virendra Singh, "Albumin: The Hepatologist's enduring ally demystified?" Science Translational Medicine, 2020 (Technical report). DOI:10.13140/RG.2.2.23484.67200

Publisher : Science Translational Medicine

Year : 2018

Dapsone-induced methemoglobinemia: Two cases and a short review

Cite this Research Publication : Valsan A, Sharma S, Mathew R, Chengappa A., "Dapsone-induced methemoglobinemia: Two cases and a short review," Journal of Applied Hematology, 9(1):p 29-32, Jan–Mar 2018. | DOI: 10.4103/joah.joah_26_17

Publisher : Journal of Applied Hematology

Year : 2017

Cognitive impairment incritically ill

Cite this Research Publication : Arun Valsan, VK Sashindran, Suman Pramanik, "Cognitive impairment incritically ill," IJAR, Vol 7, issue 02, Feb 2017

Publisher : International Journal of Advanced Research

Year : 2017

Point prevalence & risk factor assessment for hospital-acquired infections in a tertiary care hospital in Pune, India

Cite this Research Publication : Nair V, Sahni AK, Sharma D, Grover N, Shankar S, Chakravarty A, Patrikar S, Methe K, Jaiswal SS, Dalal SS, Kapur A, Verma R, Prakash J, Gupta A, Bhansali A, Batura D, Rao GG, Joshi DP, Chopra BK., "Point prevalence & risk factor assessment for hospital-acquired infections in a tertiary care hospital in Pune, India," Indian Journal of Medical Research, 2017 Jun;145(6):824-832. doi: 10.4103/ijmr.IJMR_1167_15. PMID: 29067985; PMCID: PMC5674553.

Publisher : Indian Journal of Medical Research

Year : 2017

Warfarin related acute kidney injury: A case report

Cite this Research Publication : Mendonca S, Gupta D, Valsan A, Tewari R., "Warfarin related acute kidney injury: A case report," Indian Journal of Nephrology, 2017;27:78-80. DOI: 10.4103/0971-4065.177142

Publisher : Indian Journal of Nephrology

Year : 2016

Autoimmune polyglandular syndrome type II: Schimidt’s syndrome, a unifying diagnosis in a case presenting with an uncommon combination of multiple endocrine disorders

Cite this Research Publication : Sagar A, Valsan A, Bhartiya M., "Autoimmune polyglandular syndrome type II: Schimidt’s syndrome, a unifying diagnosis in a case presenting with an uncommon combination of multiple endocrine disorders," Indian Journal of Endocrinology and Metabolism, 2016;20:579-80. DOI: 10.4103/2230-8210.183477

Publisher : Indian Journal of Endocrinology and Metabolism

Book Chapter

Year : 2022

Approach to Variceal Hemorrhage

Cite this Research Publication : Arun Valsan, A Roy, V Singh, "Approach to Variceal Hemorrhage," Clinical Rounds in Hepatology, Springer, Jan 2022. DOI-10.1007/978-981-16-8448-7-11

Publisher : Springer

Year : 2018

Preventive strategies in diabetes

Cite this Research Publication : Arun Valsan, Ranjan S., "Preventive strategies in diabetes," ICP monograph on Diabetes in elderly 2018

Year : 2018

Pathogenesis of Diabetes Mellitus in Elderly

Cite this Research Publication : Arun Valsan, Srivastava PK., "Pathogenesis of Diabetes Mellitus in Elderly," ICP monograph on Diabetes in elderly 2018

Year : 2017

Hepatitis C in Indian Subcontinent: Epidemiology, Virology, Clinical features and diagnosis

Cite this Research Publication : P Puri, A Valsan., "Hepatitis C in Indian Subcontinent: Epidemiology, Virology, Clinical features and diagnosis," ICP monologue on Viral Hepatitis in Indian Subcontinent, (pp.1-19), Chapter: 4, Publisher: Jaypee, 2017

Publisher : Jaypee Publishers

Area of Expertise
  • ACLF (Acute-on-Chronic Liver Failure)
  • Portal Hypertension
  • Transplant Hepatology and Immunology
  • Critical Care in Hepatology
  • Management of Infections in Liver Disease
  • Patient Safety and Health Care Economics
Qualification
  • MBBS, Government Medical College, Kozhikode, University of Calicut (2006)
  • MD (Internal Medicine), Armed Forces Medical College, Pune, Maharashtra University of Health Sciences (2016)
  • DNB (Internal Medicine), National Board of Examinations (2017)
  • MNAMS, National Academy of Medical Science (2018)
  • DM (Hepatology), PGIMER, Chandigarh (2021)
  • MRCP (UK), Royal College of Physicians (UK)
Work Experience
  • Assistant Professor, Amrita School of Medicine, Kochi
  • Medical Officer/Physician, Army Medical Corps/Indian Army (September 2008 – October 2018)
  • Assistant Surgeon, Primary Health Centre, Nettoor (January 2008 – July 2008)
Awards and Recognition
  • Selected for ICMR Young Medical Faculty Ph. D. program (2024)
  • Best Plenary Paper Award at INASL (2024)
  • The LTSI ROCHE Fellowship for Basic Science Research (2024)
  • AASLD Early Career Investigator Award in Clinical/Translational Science (2021)
  • Dr. Sam GP Moses Gold Medal for securing 1st rank in DNB General Medicine examination (2018)
  • Lt Gen N Krishnan Memorial Gold Medal for “The Best Bedside Clinician” (2017)
  • Multiple honors for academic excellence during MBBS and MD training
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