Course

‘Physical Pharmaceutics I – Practical’ is a course offered in the third semester of B. Pharm program at School of Pharmacy, Health Sciences campus, Amrita Vishwa Vidyapeetham.

Course Duration: 4 Hours/Week

1. Determination the solubility of drug at room temperature
2. Determination of pKa value by Half Neutralization/ Henderson Hasselbalch equation.
3. Determination of Partition co- efficient of benzoic acid in benzene and water
4. Determination of Partition co- efficient of Iodine in CCl4 and water
5. Determination of % composition of NaCl in a solution using phenol-water system by CST method
6. Determination of surface tension of given liquids by drop count and drop weight method
7. Determination of HLB number of a surfactant by saponification method
8. Determination of Freundlich and Langmuir constants using activated char coal
9. Determination of critical micellar concentration of surfactants
10. Determination of stability constant and donor acceptor ratio of PABA-Caffeine complex by solubility- method
11. Determination of stability constant and donor acceptor ratio of Cupric-Glycine complex by pH titra- tion method

Recommended Books (Latest Editions)

1. Physical Pharmacy by Alfred Martin
2. Experimental Pharmaceutics by Eugene, Parott.
3. Tutorial Pharmacy by Cooper and Gunn.
4. Stocklosam J. Pharmaceutical Calculations, Lea &Febiger, Philadelphia.
5. Liberman H.A, Lachman C., Pharmaceutical Dosage forms, Tablets, Volume-1 to 3, MarcelDekkar Inc.
6. Liberman H.A, Lachman C, Pharmaceutical Dosage forms. Disperse systems, volume 1, 2, 3. Marcel Dekkar Inc.
7. Physical Pharmaceutics by Ramasamy C and ManavalanR.
8. Laboratory Manual of Physical Pharmaceutics, C.V.S. Subramanyam, J. Thimma settee
9. Physical Pharmaceutics by C.V.S. Subramanyam
10. Test book of Physical Pharmacy, by Gaurav Jain & Roop K. Khar