Course

‘Pharmaceutical Formulations – Theory’ is a course offered in the third year of Pharm. D. program at School of Pharmacy, Health Sciences campus, Amrita Vishwa Vidyapeetham.

Course Duration: 2 Hrs./Week

Scope:

Subject deals with the formulation and evaluation of various pharmaceutical dosage forms.

Objectives

Upon completion of the subject student shall be able to (Know, do, appreci- ate) –

1. Understand the principle involved in formulation of various pharmaceutical dosage forms;
2. Prepare various pharmaceutical formulation;
3. Perform evaluation of pharmaceutical dosage forms; and
4. Understand and appreciate the concept of bioavailability and bioequivalence, their role in clinical situations.

Text books (Theory)

1. Pharmaceutical dosage forms, Vol, I,II and III by lachman
2. Rowlings Text book of Pharmaceutics
3. Tutorial Pharmacy – Cooper &Gun

Reference Books (Theory)

1. Remington’s Pharmaceutical Sciences
2. USP/BP/IP

Title of the topic

1. Pharmaceutical dosage form- concept and classification
2. Tablets: Formulation of different types of tablets, tablet excipients, granulation techniques quality con- trol and evaluation of tablets. Tablet coating, Type of coating, quality control tests for coated tablet.
3. Capsules; Production and filling of hard gelatin capsules, Raw material for shell, finishing, quality con- trol tests for capsules. Production and filling of soft gelatin capsules, quality control tests for soft gelatin capsules.
4. Liquid orals: Formulation and evaluation of suspensions, emulsions and solutions. Stability of these preparations
5. Parenterals: Introduction Containers used for Parenterals (including official tests) Formulation of large and small volume Parenterals Sterilization
6. Ophthalmic preparations (Semi – Solids): Introduction and classification Factors affecting absorption and anatomy of skin Packaging storage and labeling, Ointments Types of Ointment Base Preparation of ointment, Jellies Types of jellies Formulation of jellies Suppositories, Method of preparation, Types Packaging
7. Definition and concept of Controlled and novel Drug delivery systems with available examples, viz. parentral, trans dermal, buccal, rectal, nasal, implants, ocular