Course

Unit 1

Polymeric Nanoparticles: Synthesis of alginate nano and micro particles; characterization of particle size by Dynamic Light Scattering (DLS) and Zeta analysis Synthesis of chitosan nanoparticles; characterization of particle size by Dynamic Light Scattering (DLS) and Zeta analysis

Unit 2

Synthesis of ceramic Silica Nanoparticles and characterization using TEM. Structural characterization of crystalline and amorphous nanomaterials using X-ray diffraction spectrometer (XRD), Thermal characterization of polymers using Thermogravimetric Differential thermal Analysis (TGA-DTA)

Unit 3

Electrospinning: Fabrication of electrospun PVA nanofibres and microfibers; characterization of fibers morphology and diameter using SEM. Characterization of polymeric and inorganic samples (chitosan and TiO₂ using Raman Spectroscopy Using Raman spectroscopy)

Pre-requisites: Basic understanding of experimental research

Total number of lab sessions: 15

COURSE OUTCOME:

After successful completion of the course, students will be able to:

• Understand the principles of Dynamic Light Scattering technique in estimating the particle size and zeta potential. How zeta potential is related to the particle stability
• Understand the synthesis of polymeric Alginate nanoparticles and the role of reaction parameters that varies the particle size
• Understand the synthesis of Chitosan Nanoparticles and characterization using DLS and Zeta Potential.
• Understand the basics of vibrational spectroscopy FTIR and characterize alginate and chitosan.
• Understand the synthesis of ceramic Silica Nanoparticles and characterization using TEM.
• Understand the basics of XRD in characterizing crystalline and amorphous samples.
• Understand the thermal and mechanical characterization of polymeric samples CaCO₃ and chitosan.
• Understand the electrospinning technique and parameters that influence the formation of micro and nano fibers.
• Understand the basics of Raman spectroscopy in characterizing in polymers and inorganics samples (chitosan and TiO₂).

• Polymer Nanoparticles for Nanomedicines: A Guide for their Design, Preparation and Development; Christine Vauthier, Springer
• Nano: The Essentials; T. Pradeep, Tata McGraw-Hill
• Nanostructures & Nanomaterials: Synthesis, Properties & Applications; Guozhong Cao, Imperial College Press