Unit 1
DNA: Structure and function, Chromosome and chromatin, Genetic code, wobble hypothesis, RNA and types of RNA, Proteins and their structure
Course Name | Molecular Biology |
Course Code | 24NB632 |
Program | M. Tech. Nanobiotechnology(NBT) |
Semester | 1 |
Credits | 3 |
Campus | Kochi |
DNA: Structure and function, Chromosome and chromatin, Genetic code, wobble hypothesis, RNA and types of RNA, Proteins and their structure
DNA replication and its regulation, Homologous and site specific recombination, DNA repair
Transcription and its regulation, Translation and its regulation, Gene structure, Repeats and clusters, Gene expression regulations: operon, Epigenetics
Types of mutations, Genetic system of mitochondria
Gene identification, promoter identification, Molecular biology techniques: Isolation and Quantification of DNA/RNA, PCR, Reverse transcriptase PCR, Real Time PCR, DNA Sequence analysis, hybridization (southern, northern and western) and Sanger sequencing.
Pre-requisites: Basic level biology
Total number of classes: 45
Lewin’s Essential Genes, Jocelyn E. Krebs, Benjamin Lewin, Elliott S. Goldstein, Stephen T. Kilpatrick,Jones& Bartlett Publishers, 2013 – Science – 847 pages.
Molecular Biology of the Gene, Seventh Edition, James D. Watson, Cold Spring Harbor Laboratory; Tania A. Baker, Massachusetts Institute of Technology; Alexander Gann, Cold Spring Harbor Laboratory; Michael Levine, University of California, Berkeley; Richard Losick, Harvard University,2013
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