Unit 1

Error Analysis and Sampling: Accuracy – Precision – Classification of Errors -Minimization of errors – Standard deviation – Coefficient of variance – F-test – t-test – Significant figures. Sampling – Basis of sampling, Sampling and physical state – Safety measures of sampling.

Separation Techniques: Brief out line of column, paper and thin layer chromatography – Ion exchange methods – principle and application – HPLC.

Unit 2

Gas chromatography – principle and applications – gel chromatography.

Electroanalytical techniques: Potentiometry – Potentiometric titration – determination of equivalence point – acid base, complexometric, redox and precipitation titrations – merits and demerits. Voltammetry – Cyclic voltammetry – basic principle and application – Polarography – introduction – theoretical principles – migration current – residual current – half wave potential – instrumentation – analytical applications.

Unit 3

Spectro-chemical techniques: UV-VIS spetrophotometry – principle – Beer’s Law application – photometric titration – single and double beam spectrophotometer – instrumentation of IR – sample handling – IR applications – H – NMR – Instrumentation and applications – principle – instrumentation – applications of atomic absorption spectroscopy.

Thermal and Diffraction techniques: Principles and applications of DTG – DTA DSC – X-ray – Electron Diffraction Studies – SEM, TEM.

• Willard H W, Merritt J R, “Instrumental Methods of Analysis”, 6^th edition, Prentice Hall, (1986).
• Skoog Douglas A, West Donald, “Fundamentals of Analytical Chemistry”, 7^th edition, New York Addison, Wesley, (2001).

Reference(s)

• “Vogel’s Textbook of Quantitative Chemical Analysis”, 5th edition, ELBS, (1989).
• Kaur. H, “Instrumental Methods of Chemical Analysis”, Goel Publisher, (2001).

Evaluation Pattern

Course Outcomes

• CO1: To develop an understanding of principle and working of the range of instrumental methods in analytical chemistry
• CO2: To provide an understanding and skills in contemporary methods of separation and appropriate selection of instruments for the successful analysis of chemical compounds
• CO3: To impart skills in the scientific method of planning, conducting, reviewing, reporting experiments and problem solving in chemical analysis.