Course

‘Clinical Toxicology – Theory’ is a course offered in the fourth year of Pharm. D. program at School of Pharmacy, Health Sciences campus, Amrita Vishwa Vidyapeetham.

Course Duration: 2 Hrs./Week

1. General principles involved in the management of poisoning
2. Antidotes and the clinical applications.
3. Supportive care in clinical Toxicology.
4. Gut Decontamination.
5. Elimination Enhancement.
6. Toxicokinetics.
7. Clinical symptoms and management of acute poisoning with the following agents –
   1. Pesticide poisoning: organophosphorous compounds, carbamates, organochlorines, pyrethroids.
   2. Opiates overdose.
   3. Antidepressants
   4. Barbiturates and benzodiazepines.
   5. Alcohol: ethanol, methanol.
   6. Paracetamol and salicylates.
   7. Non-steroidal anti-inflammatory drugs.
   8. Hydrocarbons: Petroleum products and PEG.
   9. Caustics: inorganic acids and alkali.
   10. Radiation poisoning
8. Clinical symptoms and management of chronic poisoning with the following agents –Heavy metals: Arsenic, lead, mercury, iron, copper
9. Venomous snake bites: Families of venomous snakes, clinical effects of venoms, general management as first aid, early manifestations, complications and snake bite injuries.
10. Plants poisoning. Mushrooms, Mycotoxins.
11. Food poisonings
12. Envenomations – Arthropod bites and stings.

Substance abuse:

Signs and symptoms of substance abuse and treatment of dependence

1. CNS stimulants :amphetamine
2. Opioids
3. CNS depressants
4. Hallucinogens: LSD
5. Cannabis group
6. Tobacco

Reference books:

1. Matthew J Ellenhorn. ELLENHORNS MEDICAL TOXICOLOGY – DIAGNOSIS AND TREATMENT OF POISONING. Second edition. Williams and Willkins publication, London
2. V V Pillay. HANDBOOK OF FORENSIC MEDICINE AND TOXICOLOGY. Thirteenth edition 2003 Paras Pub- lication, Hyderabad