Back close

Course Detail

Course Name Therapeutics in Medicine
Course Code 24MMD312
Program B. Sc. Honors (with Research) in Molecular Medicine
Semester 6
Credits 2
Campus Kochi

Syllabus

Preamble

These are chemical entities that prevent the growth of microorganisms specifically. They are nontoxic to other organisms and are largely safe for the environment. There are different types of anti-microbial agents. In recent years, the field of therapeutics has expanded to include medications targeting specific diseases and processes, including cancer. A prominent role is played by monoclonal antibodies, engineered proteins that precisely target cancer cells.

Unit 1

Antibiotics (Bacterial cell wall synthesis, DNA replication, transcription, folate synthesis, protein synthesis inhibitors etc), Antifungal, antiviral and anti-parasitic agents and their resistance mechanisms.

Unit 2

Monoclonal Antibodies in Targeted Therapy. Introduction to monoclonal antibodies and their production methods. Mechanisms of action of different types of monoclonal antibodies used in cancer treatment (e.g., immune checkpoint inhibitors, antibody-drug conjugates).

Unit 3

Small-Molecule Inhibitors and Cellular Therapies. Targeting specific signaling pathways in cancer cells with small-molecule inhibitors.

Unit 4

CAR T-cell therapy and other emerging cellular therapies for cancer treatment, including their mechanisms of action and potential applications.

Objectives and Outcomes

Course Outcome

CO1: The students will learn about different antimicrobial agents that can be effectively used against various infectious agents.

CO2: Understand the mechanism of action of different antimicrobial drugs and targeted therapies.

CO3: Comprehend traditional and targeted therapeutic approaches.

CO4: The students will learn about various methods involved in infection control.

CO5: The students will learn to evaluate the benefits and limitations of targeted therapy.

Program Outcome

PO1: Bioscience Knowledge

PO2: Problem Analysis

PO3: Design/Development of Solutions

PO4: Conduct Investigations of complex problems

PO5: Modern tools usage

PO6: Bioscientist and Society

PO7: Environment and Sustainability

PO8: Ethics

PO9: Individual & Team work

PO10: Communication

PO11: Project management & Finance

PO12: Lifelong learning

c

C O

PO1 PO2 PO3 PO4 PO5 PO6 PO7 PO8 PO9 PO10 PO11 PO12
CO 1 3 1 2 1 3
CO 2 3 1 1 1 3
CO 3 3 1 1 1 3
CO 4 3 1 3 1 3
CO 5 3 1 1 1 3

 

Program Specific Outcomes. (PSO)

PSO 1 – Chemical and physical basis of biology

PSO 2 – Computational science in biology and medicine

PSO 3 – Biochemical and physiological complexity in biology and medicine

PSO 4 – Molecular technology in biology and medicine

PSO 5 – Cell based approaches in diagnosis and therapy

PSO 6 – Microorganisms in medicine

PSO 7 – Nanoscale entities and its significance in medicine

PSO 8 – Tissue architecture engineering in medicine

PSO 9 – Compounds as drugs and its efficacy

PSO 10 – Bioinformatics and artificial intelligence in medicine

PSO 11 –Technology in personalizing medicine

PSO 12 – Protein structural complexity in medicine

PSO 13 – Projecting science and medicine to public

CO

PSO1 PSO2 PSO3 PSO4 PSO5 PSO6 PSO7 PSO8 PSO9 PSO10 PSO11 PSO12 PSO13
CO 1 3 2 1
CO 2 3 2 3 1
CO 3 3 2 3 3 1
CO 4 3 2 3 3 1
CO 5 3 2 1

Evaluation Pattern

Internal Assessment – 50% 

Periodical 1 

Exam 

20% 

Periodical 2 

Exam 

20% 

Continuous Assessment 

Assignment/Test/Quiz

10% 

50%

End Semester Examination- 50% 

Theory Exam 

50% 

50%

Total

100%

Text Books / References

  1. Antimicrobial Agents: Antibacterials and Antifungals by André Bryskier (Editor); ASM Press.
  2. Antimicrobial Chemotherapy by David Greenwood (Editor); Oxford University Press; 4 edition.
  3. Kröger N, Gribben J, Chabannon C, et al., editors. The EBMT/EHA CAR-T Cell Handbook [Internet]. Cham (CH): Springer; 2022. Available from: https://www.ncbi.nlm.nih.gov/books/NBK584154/ doi: 10.1007/978-3-030-94353-0
  4. Human Monoclonal Antibodies: Methods and Protocols. Springer;2014

DISCLAIMER: The appearance of external links on this web site does not constitute endorsement by the School of Biotechnology/Amrita Vishwa Vidyapeetham or the information, products or services contained therein. For other than authorized activities, the Amrita Vishwa Vidyapeetham does not exercise any editorial control over the information you may find at these locations. These links are provided consistent with the stated purpose of this web site.

Admissions Apply Now