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Course Detail

Course Name Immunotherapy
Course Code 24MMD402
Program B. Sc. Honors (with Research) in Molecular Medicine
Semester 7
Credits 2
Campus Kochi

Syllabus

Preamble

The immune system main function is to ward off foreign bodies that may enter into our system as well as destroying cancer cells or can go aberrant leading development of autoimmunity. Development of drugs or cells that can alter the immune system functioning can help in restoring the immune balance leading to disease prevention/treatment. The course will help in developing an understanding the fundamental concept and associated cellular or antibody or small molecule technologies involved in, harnessing the immune response to treat infections, cancers and autoimmunity.

Unit 1

What is immunotherapy? Its historical perspectives, basis of a healthy immune system.

Unit 2

What are human immunodeficiences, Autoimmunity, Cancer immunology, Immunopathology. Significance of niche in disease pathology. Understanding the microenvironment and how this knowledge can be harnessed to treat the disease by cell therapy.

Unit 3

Issues important towards design of cellular therapeutics, Application of different strategies in the treatment of cancer and other immunological diseases, nanotechnology in cell therapy.

Unit 4

T cell and dendritic cell technologies and associated cellular therapies normally practiced in clinic.

Evaluation Pattern

Internal Assessment – 50% 

Periodical 1 

Exam 

20% 

Periodical 2 

Exam 

20% 

Continuous Assessment 

Assignment/Test/Quiz

10% 

   

50% 

End Semester Examination- 50% 

Theory Exam 

50% 

 
   

50%

 

Total

100%

Text Books / References

  1. The Immunotherapy Revolution (Publisher: Gatekeeper Press Author: Williams Jason R,)
  2. Cancer Immunology and Immunotherapy; (Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG; Edited by Glenn Dranoff)

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