| Course Name | Immunology |
| Course Code | 24MMD202 |
| Program | B. Sc. Honors (with Research) in Molecular Medicine |
| Semester | 3 |
| Credits | 2 |
| Campus | Kochi |
Understanding the players of defense mechanism and how it functions as a system in protecting humans are extremely important in the keeping up the homeostasis and has immense significance in diseases including cancer. Here students are exposed to these aspects contextually for a better understanding of the subject and its implications in developing therapies
Immune system, Concept of Innate and Adaptive immunity; Immune Cells and Organs. Antigens; Adjuvants; Antibodies; Antigenic determinants on antibodies; VDJ rearrangements; Monoclonal and Chimeric antibodies
Major Histocompatibility (Organization of MHC locus (Mice & Human); Structure and Functions of MHC I & II molecules; Antigen processing and presentation. Cytokines, Cross talk between immune cells and the role of cytokines.
Complement System. Generation of Immune Response, Introduction to tolerance, Immunological Disorders and Tumor Immunity.
Types of autoimmunity and hypersensitivity with examples; Immunodeficiencies – Animal models (Nude and SCID mice), SCID, DiGeorge syndrome, Chediak- Higashi syndrome
Immunological Techniques (Principles of Precipitation, Agglutination, Immunodiffusion, Immunoelectrophoresis, ELISA, ELISPOT, Western blotting, Immunofluoresence, Flow cytometry, Immunoelectron microscopy).
Course Outcome
CO1 Gain knowledge about cellular and molecular basis of immunity and immune systems.
CO2 The students will learn the role of the immune system in maintaining balance in healthy versus diseased conditions.
CO3 The students will learn about the molecular events involved in generating innate, humoral and cell-mediated immunity
CO4 They will learn regarding the basis of allergic diseases and autoimmunity.
CO5 The students will learn about various immunological diagnostic techniques
Program Outcome
PO1: Bioscience Knowledge
PO2: Problem Analysis
PO3: Design/Development of Solutions
PO4: Conduct Investigations of complex problems
PO5: Modern tools usage
PO6: Bioscientist and Society
PO7: Environment and Sustainability
PO8: Ethics
PO9: Individual & Team work
PO10: Communication
PO11: Project management & Finance
PO12: Lifelong learning
| c
C O |
PO1 | PO2 | PO3 | PO4 | PO5 | PO6 | PO7 | PO8 | PO9 | PO10 | PO11 | PO12 |
| CO 1 | 3 | 1 | 1 | 2 | – | 1 | – | – | – | – | – | 3 |
| CO 2 | 3 | 1 | 1 | 2 | – | 1 | – | – | – | – | – | 3 |
| CO 3 | 3 | 1 | 1 | 2 | – | 1 | – | – | – | – | – | 3 |
| CO 4 | 3 | 1 | 1 | 2 | – | 1 | – | – | – | – | – | 3 |
| CO 5 | 3 | 1 | 1 | 2 | – | 1 | – | – | – | – | – | 3 |
3 = High Affinity, 2 = Medium Affinity, 1 = Low Affinity, – = No Affinity
Program Specific Outcomes. (PSO)
PSO 1 – Chemical and physical basis of biology
PSO 2 – Computational science in biology and medicine
PSO 3 – Biochemical and physiological complexity in biology and medicine
PSO 4 – Molecular technology in biology and medicine
PSO 5 – Cell based approaches in diagnosis and therapy
PSO 6 – Microorganisms in medicine
PSO 7 – Nanoscale entities and its significance in medicine
PSO 8 – Tissue architecture engineering in medicine
PSO 9 – Compounds as drugs and its efficacy
PSO 10 – Bioinformatics and artificial intelligence in medicine
PSO 11 –Technology in personalizing medicine
PSO 12 – Protein structural complexity in medicine
PSO 13 – Projecting science and medicine to public
| –
C O |
PSO1 | PSO2 | PSO3 | PSO4 | PSO5 | PSO6 | PSO7 | PSO8 | PSO9 | PSO10 | PSO11 | PSO12 | PSO13 |
| CO 1 | – | – | 3 | – | – | 1 | – | – | – | – | – | – | – |
| CO 2 | – | – | 3 | – | – | 1 | – | – | – | – | – | – | – |
| CO 3 | – | – | 3 | – | – | 1 | – | – | – | – | – | – | – |
| CO 4 | – | – | 3 | – | – | 1 | – | – | – | – | – | – | – |
| CO 5 | – | – | 3 | – | 2 | 1 | – | – | – | – | – | – | – |
|
Internal Assessment – 50% |
||
|
Periodical 1 |
Exam |
20% |
|
Periodical 2 |
Exam |
20% |
|
Continuous Assessment |
Assignment/Test/Quiz |
10% |
|
50% |
||
|
End Semester Examination- 50% |
||
|
Theory Exam |
50% |
|
|
50% |
||
|
Total |
100% |
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