| Course Name | Developmental Biology |
| Course Code | 24MMD201 |
| Program | B. Sc. Honors (with Research) in Molecular Medicine |
| Semester | 3 |
| Credits | 2 |
| Campus | Kochi |
This course will describe the general patterns and mechanisms involved in the development of bilateral organisms including the mammals. Specifically, the course will deal with sex determination, gametogenesis, developmental organization, axis formation, 3 germ layer formation, organogenesis and implications of development in health and disease. The course is expected to provide the students a deeper understanding about the developmental origin of health and disease in adulthood.
Patterns and Processes of Becoming: A Framework for Understanding Animal Development (Making New Bodies: Mechanisms of Developmental Organization; Specifying Identity: Mechanisms of Developmental Patterning; Differential Gene Expression: Mechanisms of Cell Differentiation; Cell-to-Cell Communication: Mechanisms of Morphogenesis).
Gametogenesis and Fertilization: The Circle of Sex (Sex Determination and Gametogenesis; Fertilization: Beginning a New Organism).
Early Development: Cleavage, Gastrulation, and Axis Formation (The Genetics of Axis Specification in Mammals).
Building with Ectoderm: Neural Tube Formation and Patterning; Brain Growth; Neural Crest Cells and Axonal Specificity.
Building with Mesoderm and Endoderm: Organogenesis; Paraxial Mesoderm: The Somites and Their Derivatives; Intermediate and Lateral Plate Mesoderm: Heart, Blood, and Kidneys; The Endoderm: Tubes and Organs for Digestion and Respiration
Postembryonic Development: Regeneration; Aging and Senescence
Development in Wider Contexts: Development in Health and Disease: Birth Defects; Development and the Environment: Biotic, Abiotic, and Symbiotic Regulation of Development; Development and Evolution: Developmental Mechanisms of Evolutionary Change.
Course Outcome
CO1 To understand the journey of an animal embryo from a single cell to a multicellular organism and development of personhood
CO2 To learn about sexual development of an organism and how a preexisting organism makes a new organism through reproduction
CO3 To learn about the three germ layers, ectoderm, mesoderm and endoderm, and building of organs from each germ layer
CO4 To learn about post embryonic development, regeneration, aging and senescence
CO5 To have a perspective about development in wider contexts like health and disease, environmental regulation of development and developmental mechanisms underlying evolutionary changes
Program outcome
PO1: Bioscience Knowledge
PO2: Problem Analysis
PO3: Design/Development of Solutions
PO4: Conduct Investigations of complex problems
PO5: Modern tools usage
PO6: Bioscientist and Society
PO7: Environment and Sustainability
PO8: Ethics
PO9: Individual & Team work
PO10: Communication
PO11: Project management & Finance
PO12: Life long learning
3 = High Affinity, 2 = Medium Affinity, 1 = Low Affinity, – = No Affinity
| c
C O |
PO1 | PO2 | PO3 | PO4 | PO5 | PO6 | PO7 | PO8 | PO9 | PO10 | PO11 | PO12 |
| CO 1 | 3 | 1 | 2 | 2 | 2 | 3 | 2 | – | – | – | – | 3 |
| CO 2 | 3 | 1 | 2 | 2 | 2 | 3 | 2 | – | – | – | – | 3 |
| CO 3 | 3 | 1 | 2 | 2 | 2 | 3 | 2 | – | – | – | – | 3 |
| CO 4 | 3 | 1 | 2 | 2 | 2 | 3 | 2 | – | – | – | – | 3 |
| CO 5 | 3 | 1 | 2 | 2 | 2 | 3 | 3 | – | – | – | – | 3 |
Program Specific Outcomes. (PSO)
PSO 1 – Chemical and physical basis of biology
PSO 2 – Computational science in biology and medicine
PSO 3 – Biochemical and physiological complexity in biology and medicine
PSO 4 – Molecular technology in biology and medicine
PSO 5 – Cell based approaches in diagnosis and therapy
PSO 6 – Microorganisms in medicine
PSO 7 – Nanoscale entities and its significance in medicine
PSO 8 – Tissue architecture engineering in medicine
PSO 9 – Compounds as drugs and its efficacy
PSO 10 – Bioinformatics and artificial intelligence in medicine
PSO 11 –Technology in personalizing medicine
PSO 12 – Protein structural complexity in medicine
PSO 13 – Projecting science and medicine to public
| –
C O |
PSO1 | PSO2 | PSO3 | PSO4 | PSO5 | PSO6 | PSO7 | PSO8 | PSO9 | PSO10 | PSO11 | PSO12 | PSO13 |
| CO 1 | 3 | – | 3 | 2 | 1 | – | – | 3 | – | – | – | – | 3 |
| CO 2 | 3 | – | 3 | 2 | 1 | – | – | 3 | – | – | – | – | 3 |
| CO 3 | 3 | – | 3 | 2 | 1 | – | – | 3 | – | – | – | – | 3 |
| CO 4 | 3 | – | 3 | 2 | 1 | – | – | 3 | – | – | – | – | 3 |
| CO 5 | 3 | – | 3 | 2 | 1 | – | – | 3 | – | – | – | – | 3 |
|
Internal Assessment – 50% |
||
|
Periodical 1 |
Exam |
20% |
|
Periodical 2 |
Exam |
20% |
|
Continuous Assessment |
Assignment/Test/Quiz |
10% |
|
50% |
||
|
End Semester Examination- 50% |
||
|
Theory Exam |
50% |
|
|
50% |
||
|
Total |
100% |
(1) Gilbert: Developmental Biology (11th ed., 2006, Sinauer);
(2) Balinsky: An Introduction to Embryology (1981, CBS);
(3) Wolpert: Principles of Development (3rd ed. 2007, Oxford).
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