| Course Name | Biochemistry |
| Course Code | 24MMD101 |
| Program | B. Sc. Honors (with Research) in Molecular Medicine |
| Semester | 1 |
| Credits | 2 |
| Campus | Kochi |
Biochemistry is the branch of science that explores the chemical processes within and related to living organisms. Biochemistry -1 deals with the basic introduction, focusing primarily on the amino acids and proteins. The course will make the students understand the structure of amino acids, proteins, role of proteins in different biochemical context etc.
Foundations of biochemistry, cellular composition; chemical foundations; carbon compounds as functional groups in biomolecules; macromolecular constituents of cell; Conformation and configuration of macromolecules; Physical foundations, dynamic steady state in living organism, flow of electrons; Energy coupling link reactions
Composition of Amino acids; different types of amino acids; Amino acids and their properties – hydrophobic, polar and charged; Peptide bond; Amino acids as source for energy production; Amino acids are derivatives for various metabolites.
Protein as a biopolymer; covalent structure of proteins; Primary sequence of proteins; Three-dimensional structure of proteins; Protein denaturation and folding.
Role of proteins in different biochemical contexts – Enzymes, Receptors, Signaling molecules, Carriers of different cargos and elements. Fundamentals of signaling mechanisms.
Course outcome ( CO )
CO1: Understand the basic foundations of biochemistry
CO2: Understand the transformation of energy and matter in steady state maintenance of living organism
CO3: Understand the basic structure of amino acids along with their classification
CO4: Basic understanding of different levels of protein structure and folding
CO5: Significance of enzymes, receptors, and signaling molecules in living organisms
Program outcome ( PO )
PO1: Bioscience Knowledge
PO2: Problem Analysis
PO3: Design/Development of Solutions
PO4: Conduct Investigations of complex problems
PO5: Modern tools usage
PO6: Bioscientist and Society
PO7: Environment and Sustainability
PO8: Ethics
PO9: Individual & Team work
PO10: Communication
PO11: Project management & Finance
PO12: Lifelong learning
3 = High Affinity, 2 = Medium Affinity, 1 = Low Affinity, – = No Affinity
| PO1 | PO2 | PO3 | PO4 | PO5 | PO6 | PO7 | PO8 | PO9 | PO10 | PO11 | PO12 | |
| CO 1 | 3 | 1 | – | – | – | – | 2 | – | – | – | – | 1 |
| CO 2 | 3 | 1 | – | – | – | – | 3 | – | – | – | – | 1 |
| CO 3 | 3 | 1 | – | – | – | – | – | – | – | – | – | 1 |
| CO 4 | 3 | 2 | 3 | – | 2 | – | – | – | – | – | – | 1 |
| CO 5 | 3 | 2 | 3 | 3 | 3 | 2 | – | – | – | – | – | 1 |
Program Specific Outcome ( PSO )
PSO 1 – Chemical and physical basis of biology
PSO 2 – Computational science in biology and medicine
PSO 3 – Biochemical and physiological complexity in biology and medicine
PSO 4 – Molecular technology in biology and medicine
PSO 5 – Cell based approaches in diagnosis and therapy
PSO 6 – Microorganisms in medicine
PSO 7 – Nanoscale entities and its significance in medicine
PSO 8 – Tissue architecture engineering in medicine
PSO 9 – Compounds as drugs and its efficacy
PSO 10 – Bioinformatics and artificial intelligence in medicine
PSO 11 – Technology in personalizing medicine
PSO 12 – Protein structural complexity in medicine
PSO 13 – Projecting science and medicine to public
|
PSO1 |
PSO2 |
PSO3 |
PSO4 |
PSO5 |
PSO6 |
PSO7 |
PSO8 |
PSO9 |
PSO10 |
PSO11 |
PSO12 |
PSO13 |
|
|
CO 1 |
3 |
– |
1 |
– |
– |
– |
– |
– |
– |
– |
– |
– |
– |
|
CO 2 |
3 |
– |
1 |
– |
– |
– |
– |
– |
– |
– |
– |
– |
– |
|
CO 3 |
3 |
– |
2 |
– |
– |
– |
– |
– |
– |
– |
– |
– |
– |
|
CO 4 |
3 |
3 |
3 |
– |
– |
– |
– |
– |
– |
– |
– |
3 |
2 |
|
CO 5 |
3 |
2 |
3 |
1 |
2 |
– |
– |
– |
2 |
2 |
– |
3 |
2 |
| Internal Assessment – 50% | ||
| Periodical 1 | Exam | 20% |
| Periodical 2 | Exam | 20% |
| Continuous Assessment | Assignment/Test/Quiz | 10% |
| 50% | ||
| End Semester Examination- 50% | ||
| Theory Exam | 50% | |
| 50% | ||
| Total | 100% |
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