| Course Name | Bio Physics |
| Course Code | 24MMD111 |
| Program | B. Sc. Honors (with Research) in Molecular Medicine |
| Semester | 2 |
| Credits | 2 |
| Campus | Kochi |
Connecting Physics to biology is an essential factor which eventually determines quantifying primary factors in a physical process that occur at cell level. Physics serves as a nanoscopic visualization tool to dissect such processes to reveal the information to students. This course introduces applications of Physics into Biology.
Spectroscopy: Principle, instrumentation and application of spectroscopic instruments: UV Visible absorption spectroscopy, Colorimeter, IR spectroscopy, Raman spectroscopy
Bioenergetics: Laws of thermodynamics. Concept of state functions, free energy change, equilibrium constant, coupled reactions, energy charge, ATP cycle, phosphorylation potential, and phosphoryl group transfers. Electron transport in membrane for oxidative phosphorylation, Chemical basis of hydrolysis of ATP and thioesters. Redox reactions, standard redox potentials and Nernst equation.
Microscopy: Principle, instrumentation and application of Microscopy, Optical Microscope, Fluorescent Microscope, Confocal Microscope,Electron Microscope, Applications of each microscopic method.
Biophysics in Diagoinsitc Medicine: Principles of Medical-imaging, Instrumentation and Working principles and Medical applications of X-ray Imaging,CT, US and MRI, PET SPECT. Monitoring and recording bioelectric signals, Transducers in physiology.
Biophysics in Theragnostics Medicine: Diagnostic and Therapeutic Techniques: Cardiac pace makers, Blood flow monitors, Pulmonary function analyzers, Hemodialysis machines, Defibrillators, Short/ wave diathermy, Electrically stimulated pain management, Laser: operating principles, types, Biomedical applications in surgery.
Introduction to the Physics connection and its role in knowing and understanding Biology from cellular to whole organism.
Course outcome
CO1 – Introduction to Physics and its importance and connection to biology
CO2 – Thermodynamic laws applied to cellular respiration
CO3 – Physics principles for Bio medical Imaging
CO4 – Bio-physics of some of medical diagnostics and treatment tools.
CO5 – Nanophotonics for Biology and Nanomedicine
Program Outcomes (PO) (As given by NBA and ABET)
PO1: Bioscience Knowledge
PO2: Problem Analysis
PO3: Design/Development of Solutions
PO4: Conduct Investigations of complex problems
PO5: Modern tools usage
PO6: Bioscientist and Society
PO7: Environment and Sustainability
PO8: Ethics
PO9: Individual & Team work
PO10: Communication
PO11: Project management & Finance
PO12: Lifelong learning
| c | PO1 | PO2 | PO3 | PO4 | PO5 | PO6 | PO7 | PO8 | PO9 | PO10 | PO11 | PO12 |
| C O | ||||||||||||
| CO 1 | 1 | 1 | 1 | – | 2 | 2 | 2 | 1 | 1 | 2 | – | 3 |
| CO 2 | 2 | 1 | 2 | – | – | 1 | 1 | – | 1 | – | – | 1 |
| CO 3 | 2 | 1 | 1 | – | 3 | 1 | – | – | 1 | – | – | – |
| CO 4 | 1 | 3 | ||||||||||
| CO 5 | 1 | 2 | 2 |
3 = High Affinity, 2 = Medium Affinity, 1 = Low Affinity, – = No Affinity
Program Specific Outcomes.(PSO)
PSO 1 – Chemical and physical basis of biology
PSO 2 -Computational science in biology and medicine
PSO 3 -Biochemical and physiological complexity in biology and medicine
PSO 4 -Molecular technology in biology and medicine
PSO 5 – Cellbased approaches in diagnosis and therapy
PSO 6 -Microorganisms in medicine
PSO 7 -Nanoscale entities and its significance in medicine
PSO 8 – Tissue architecture engineering in medicine
PSO 9 – Compounds as drugs and its efficacy
PSO 10 – Bioinformatics and artificial intelligence in medicine
PSO 11 –Technology in personalizing medicine
PSO 12 – Protein structural complexity in medicine
PSO 13 – Projecting science and medicine to public
| – | PSO1 | PSO2 | PSO3 | PSO4 | PSO5 | PSO6 | PSO7 | PSO8 | PSO9 | PSO10 | PSO11 | PSO12 | PSO13 |
| C O | |||||||||||||
| CO 1 | 2 | 1 | – | – | – | – | 1 | 1 | – | – | – | – | 3 |
| CO 2 | 2 | – | 1 | – | – | – | – | – | – | – | – | – | 1 |
| CO 3 | 1 | 1 | 1 | – | 1 | – | – | – | – | – | – | – | 1 |
| CO 4 | 1 | 1 | 2 | 2 | 1 | – | – | – | – | 2 | 2 | – | 1 |
| CO 5 | – | 1 | 1 | 2 | 1 | – | 3 | 1 | 1 | – | 1 | – | 1 |
| Internal Assessment – 50% | ||
| Periodical 1 | Exam | 20% |
| Periodical 2 | Exam | 20% |
| Continuous Assessment | Assignment/Test/Quiz | 10% |
| 50% | ||
| End Semester Examination- 50% | ||
| Theory Exam | 50% | |
| 50% | ||
| Total | 100% |
(1) Biophysics: An Introduction by Rodney M. J. Cotterill, Published by John Wiley & Sons Ltd, 2002.
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