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Research & Projects

Research at ACNSMM includes development of disease specific nanomedicines, identification of molecular markers for clinical conditions, designing novel delivery systems for use in wound healing, nervous system, cardiovascular ailments, and many others. The department also has a strong bioinformatics unit, along with 3D bioprinting , stem cell program, and tissue regeneration laboratories. Parallelly, the center also houses the Renewable and Energy storage division that focuses on research that supports generation of clean and sustainable forms of energy.

Amrita Center for Nanosciences has several common facilities to aid research labs conduct work related to their specialities.

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Nano-characterisation Facility

The lab is equipped with FTIR, UV-VIS Spectrophotometer, Spectrofuorimeter, Thermal Analysis Systems (DSC, TGA/DTA) and Particle Sizer with Zeta Potential Analyser for physiochemical characterization of nanomaterials.

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Cell Culture & Stem Cell Facility

The lab is equipped with Cell/ Stem Cell/ Tissue Culture Facility with Biological Safety Cabinets, CO2 Incubator, Inverted Microscope, Fluorescent Microscope, Liquid N2 Facility, – 80°C freezer, -20°C freezer, etc.

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High-resolution Imaging Facility

The lab has state-of-the-art microscopes including a high resolution Scanning Electron microscope, Atomic Force microscope and Fluorescence microscope. Other additions to the lab include the new generation Spectral Confocal Laser Scanning microscope and the transmission electron microscope.

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Nanotoxicology Facility

The lab is equipped with a non-invasive, whole animal multispectral imaging system having fluorescence and X – ray imaging capabilities.

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Nanochemistry and Electrospinning Facility

The lab is equipped for wet chemical processing of various types of nanomaterials such as inorganic, metallic and polymeric nanoparticles. An electrospinning set-up is also available for developing nanofibrous scaffolds and structures.

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Flow Cytometry and Cell Sorting Facility

The FACS lab is equipped to handle both, clinical and research samples. Currently, it is equipped with two flow cytometers and is one of the heavily used services.

Book Chapter

Therapeutic Potential of N-Type Voltage-Gated Ca2+ Channel

Publisher : Ion Channels and Their Inhibitors

QSAR Models towards Cholinesterase Inhibitors for the Treatment of Alzheimer’s Disease

Publisher : Oncology: Breakthroughs in Research and Practice

In Silico Modeling of FDA-Approved Drugs for Discovery of Anti-cancer Agents: A Drug Repurposing Approach

Publisher : “In Silico Drug Design: Repurposing Techniques and Methodologies

Impact of Target-Based Drug Design in Anti-bacterial Drug Discovery for the Treatment of Tuberculosis

Publisher : Structural Bioinformatics- Applications in Preclinical Drug Discovery Process”, The Challenges and Advances in Computational Chemistry and Physics series

Structural Bioinformatics- Applications in Preclinical Drug Discovery Process

Publisher : The Challenges and Advances in Computational Chemistry and Physics series (Book title) Springer Nature Publisher

Conference Paper

Titania Nanotubes loaded with zinc oxide nanoparticles for improved osseointegration and antibacterial activity

Publisher : International Conference on Biotechnology for Innovative applications – Amrita Bioquest

Polymeric fiber containing nanohydroxyapatite based composite scaffolds for bone tissue engineering

Publisher : International Conference on Biotechnology for Innovative applications – Amrita Bioquest

Characterization of 3D bony scaffold of NanoHA-gelatin with PLLA electrospun sheet

Publisher : International Conference on Biotechnology for Innovative applications – Amrita Bioquest

Surgical alterations to enhance prosthetic outcome in maxillofacial rehabilitation

Publisher : International Society for Maxillofacial Rehabilitation Conference China

Localized Drug Delivery in Bone tissue Engineering

Publisher : National Seminar on Recent Advances in Biotechnology

Relevance of Fiber Reinforced Gelatin-HA Composite Scaffold For Bone Tissue Regeneration

Publisher : Indo-Australian Conference on Biomaterials Tissue Engineering – BiTERM

Development of composite scaffolds with genetically engineered stem cells expressing BMP2 for bone tissue engineering

Publisher : Indo-Australian Conference on Biomaterials Tissue Engineering – BiTERM

Ciprofloxacin loaded gelatin-hydroxyapatite scaffolds as a local drug delivery system for osteomyelitis treatment

Publisher : Indo-Australian Conference on Biomaterials Tissue Engineering – BiTERM

Gelatinous matrix with Silica coated Nanohydroxyapatite as a Biomimetic scaffold for Bone Tissue Engineering

Publisher : NUS Joint International Conference on Biotechnology and Neuroscience – CUSBAN

Locating emergency responders in disaster area using wireless sensor network

Publisher : Lecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering

Signalling activity of staphylococcal cell wall components

Publisher : INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Characterisation of cell wall hydrolases in Staphylococcus sp.

Publisher : INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Conference Proceedings

Studies on Defect Mediated Charge Transport and Recombination Dynamics in SnO2 Based Dye Sensitized Solar Cells

Publisher : Third International Conference on Nanomaterials: Synthesis, Characterization and Applications,

Effect of 2D Layered WS2 Nanoflakes on SnO2 Based Dye Sensitized Solar Cell Performance

Publisher : Third International Conference on Nanomaterials: Synthesis, Characterization and Applications

Journal Article

Chitin Scaffolds in Tissue Engineering

Publisher : International Journal of Molecular Sciences

Dirofilarial adult worms can also dance.

Publisher : Clinical Microbiology and Infection

Hematotoxicological analysis of surface-modified and -unmodified chitosan nanoparticles

Publisher : Journal of Biomedical Materials Research – Part A

Adult Stem Cells on Methacrylic Acid Grafted Cocoon Silky Fibrous Scaffolds

Publisher : Trends in Biomaterials and Artificial Organs

Impact of Computational Structure-Based Predictive Toxicology in Drug Discovery

Publisher : Combinatorial Chemistry High Throughput Screening

Multiscale fibrous scaffolds in regenerative medicine

Publisher : Advances in Polymer Science

Tetracycline Nanoparticles Loaded Calcium Sulfate Composite Beads for Periodontal Management

Publisher : Biochimica et Biophysica Acta – General Subjects

Chitin and Chitosan in Selected BiomedicalApplications

Publisher : Progress in Polymer Science

Author Index

Publisher : Molecular Microbiology

Uridine monophosphate kinase as potential target for tuberculosis: from target to lead identification

Publisher : Interdisciplinary Sciences: Computational Life Sciences (Springer)

Characterization of an injectable, degradable polymer for mechanical stabilization of mandibular fractures

Publisher : Journal of Biomedical Materials Research Part B: Applied Biomaterials

Applications of Titania Nanotubes in Bone Biology

Publisher : Journal of Nanoscience and Nanotechnology

Skin and muscle permeating antibacterial nanoparticles for treating Staphylococcus aureus infected wounds

Publisher : Journal of Biomedical Materials Research – Part B Applied Biomaterials

The exploration of thienothiazines as selective butyrylcholinesterase inhibitors

Publisher : European Journal of Pharmaceutical Sciences

In vitro evaluation of electrospun PCL/nanoclay composite scaffold for bone tissue engineering

Publisher : Journal of Materials Science: Materials in Medicine

Curcumin Loaded Fibrinogen Nanoparticles for Cancer Drug Delivery

Publisher : Journal of Biomedical Nanotechnology

MRI and CT Contrast-enabled Composite Implants for Image-guided Tissue Regeneration and Therapy (Filed)

Publisher : MRI and CT Contrast-Enabled Composite Implants for Image-Guided Tissue Regeneration and Therapy

Chitin Scaffolds in Tissue Engineering

Publisher : International Journal of Molecular Sciences

5-Fluorouracil Loaded Fibrinogen Nanoparticles for Cancer Drug Delivery Applications

Publisher : International Journal of Biological Macromolecules

Supercapacitors based on microporous β-Ni(OH)2 nanorods

Publisher : Colloids and Surfaces A: Physicochemical and Engineering Aspects

Designing Scaffolds for Bone Tissue Engineering

Publisher : Translating Biomaterials for Bone Graft: Bench-Top to Clinical Applications

Advantages of chitin-based nanobiomaterials in nanomedicine

Publisher : Marine Biomaterials: Characterization, Isolation and Applications

Chitosan-Conjugated DNA Nanoparticle Delivery Systems for Gene Therapy

Publisher : Chitin, Chitosan, Oligosaccharides and Their Derivatives: Biological Activities and Applications

Antibiotic Resistance in Pseudomonas Aeruginosa and Alternative Therapeutic Options

Publisher : International Journal of Medical Microbiology

Autolysin Mediated Adherence of Staphylococcus Aureus with Fibronectin, Gelatin and Heparin.

Publisher : International Journal of Biological Macromolecules

Multifaceted Chitin/poly (lactic-co-glycolic) Acid Composite Nanogels

Publisher : International journal of biological macromolecules

Amidase encapsulated O-carboxymethyl chitosan nanoparticles for vaccine delivery

Publisher : International Journal of Biological Macromolecules

Lipopeptides in the triggering of erythrocyte cell membrane scrambling

Publisher : Cellular Physiology and Biochemistry

Long-term Drug Delivery using Implantable Electrospun Woven Polymeric Nanotextiles

Publisher : Nanomedicine: Nanotechnology, Biology, and Medicine

Cobalt oxide thin films for high capacity and stable Li-ion battery anode

Publisher : Journal of Solid State Electrochemistry

Photo-Enhanced Supercapacitive Behaviour of Photoactive Cu2FeSnS4 (CFTS) Nanoparticles

Publisher : Journal of Materials Science: Materials in Electronics

Nanoparticle formulations for delivering multiple therapeutic agents

Publisher : Nanoparticle Formulations for Delivering Multiple Therapeutic Agents

Investigation of Organic Small Molecules and Polymer Compounds for CdTe back Contact

Publisher : Conference Record of the IEEE Photovoltaic Specialists Conference

Strategies for Targeting Cancer Immunotherapy Through Modulation of the Tumor Microenvironment

Publisher : Regenerative Engineering and Translational Medicine

Effect of peptidoglycans on erythrocyte survival

Publisher : International Journal of Medical Microbiology

Acitretin and Aloe-Emodin Loaded Chitin Nanogel for the Treatment of Psoriasis

Publisher : European Journal of Pharmaceutics and Biopharmaceutics

APC sensitive gastric acid secretion

Publisher : Cellular Physiology and Biochemistry

Cell Interaction Studies with Bioglass Coated Hydroxyapatite Porous Blocks

Publisher : Trends in Biomaterials and Artificial Organs

Activity of the major staphylococcal autolysin Atl

Publisher : FEMS Microbiology Letters

Therapeutic Potential of Voltage Gated Calcium Channels

Publisher : Mini Reviews in Medicinal Chemistry

Patents

Cartridge Connection Method for Precise Delivery of Liquid

Publisher : Cartridge Connection Method for Precise Delivery of Liquid

Targeted Nano-photomedicines for Photodynamic Therapy of Cancer (Chinese)

Publisher : Targeted Nano-photomedicines for Photodynamic Therapy of Cancer (Chinese)

Compositions and Methods for Autoimmune Disease Treatment Inventors

Publisher : U.S. Patent Australian Provisional Patent Application no: 2016903294

Composition and Methods for Autoimmune Disease Treatment

Publisher : U.S. Patent PCT/US17/47778 – PCT (Patent Filed)2017

Porous Composite Fibrous Scaffold for Bone Tissue Regeneration

Publisher : U.S. Patent 5919/CHE/20152015.

Other

A Stiff Injectable Biodegradable Elastomer

Publisher : Advanced Functional Materials

Prolonged Nerve Blockade Delays the Onset of Neuropathic Pain

Publisher : Proceedings of the National Academy of Sciences

Electrospun Drug-eluting Sutures for Local Anesthesia

Publisher : Journal of Controlled Release

Advances in cancer nanomedicine

Publisher : Journal of the Indian Institute of Science

Dielectric properties of iron doped calcium copper titanate, CaCu3Ti3. 9Fe0. 1O12 ceramic

Publisher : Journal of Materials Science: Materials in Electronics

Effect of cooling time on the vapor liquid solid based growth of gold-catalyzed bismuth nanorods

Publisher : Physica E: Low-dimensional Systems and Nanostructures

Chitin and Chitosan as Hemostatic Agents

Publisher : Encyclopedia of Polymer Science and Technology

Hematotoxicological analysis of surface-modified and -unmodified chitosan nanoparticles

Publisher : Journal of Biomedical Materials Research – Part A

Biomedical Applications of Graphene: Opportunities and Challenges

Publisher : Graphene: Synthesis, Properties, and Phenomena

Curcumin-loaded N, O-carboxymethyl chitosan nanoparticles for cancer drug delivery

Publisher : Journal of Biomaterials Science, Polymer Edition

Current voltage analysis and band diagram of Ti/TiO 2 nanotubes Schottky junction

Publisher : Applied Physics A: Materials Science and Processing

Photoanode Activity of ZnO Nanotube Based Dye-Sensitized Solar Cells

Publisher : Journal of Materials Science and Technology

Chitosan-Based Nanoparticles in Cancer Therapy

Publisher : Advances in Polymer Science

Neuroglia as Targets for Drug Delivery Systems: A Review

Publisher : Nanomedicine: Nanotechnology, Biology, and Medicine

Development of Novel Fibrinogen Nanoparticles by Two-step Co-acervation Method

Publisher : International Journal of Biological Macromolecules

Sex determination in fishes

Publisher : Hormones and reproduction of vertebrates: fishes

Sexual Behavior in Teleosts: Role of Gonadal Hormones

Publisher : Indian Journal of Science and Technology

Studies on Charge Transport and Recombination in MoO3 Coated SnO2 Based Dye Sensitized Solar Cells

Publisher : Third International Conference on Nanomaterials: Synthesis, Characterization and Applications

Electrospinning Apparatus and Method for Producing Multi-Dimensional Structures and Core-Sheath Yarns

Authors : Deepthy Menon; John Joseph; Shantikumar Nair

Publisher : US Patent 9994975B2

Review on Dye-sensitized Solar Cells based on Polymer Electrolytes

Publisher : International Journal of Engineering and Technology(UAE)

Electro Chemical Impedance Spectrscopic Analysis of Nb2O5 Blocking layer in Dye Sensitised Solar Cells

Publisher : 2016 International Conference on Electrical, Electronics, and Optimization Techniques (ICEEOT)

Nanoparticles as Drug Delivery Vehicles for the Therapy of Inflammatory Disorders

Publisher : Handbook of Immunological Properties of Engineered Nanomaterials

Fabrication of CdSe Sensitized SnO2 Nanofiber Quantum Dot Solar Cells

Publisher : Materials Science in Semiconductor Processing

Chitosan-Gelatin Composite Scaffolds in Bone Tissue Engineering

Publisher : Chitin and Chitosan for Regenerative Medicine

Hybrid fields unleashing wider scope in research frontiers: Editorial

Publisher : Trends in Biomaterials and Artificial Organs

Role of Nanogrooves on the Performance of Ultra-fine Grained Titanium as a Bio-Implant

Publisher : Advanced Nanomaterials: Synthesis, Properties, and Applications

Hydrothermal Assisted Heterogeneous MoS2 Enabled Performance Enhancement in Dye Sensitized Solar Cells

Publisher : Third International Conference on Nanomaterials: Synthesis, Characterization and Applications

Graphene Quantum Dots Enabled Photoabsorption in Mesoporous TiO2 for Excitonic Solar Cell Application

Publisher : Third International Conference on Nanomaterials: Synthesis, Characterization and Applications

FTO/TiO2 Interface Engineering by MoO3 Thin Films for Dye Sensitized Solar Cell Applications

Publisher : Third International Conference on Nanomaterials: Synthesis, Characterization and Applications

2D Layered MoS2 Enabled Photo-responsive Characteristics in TiO2 Nanoparticle Film

Publisher : Third International Conference on Nanomaterials: Synthesis, Characterization and Applications

Preparative Methods of Phosphorylated Chitin and Chitosan—An Overview

Publisher : International Journal of Biological Macromolecules

Near-Infrared-Actuated Devices for Remotely Controlled Drug Delivery

Publisher : Proceedings of the National Academy of Sciences of the United States of America

Carbohydrate-based Nanogels as Drug and Gene Delivery Systems

Publisher : Journal of Nanoscience and Nanotechnology

The role of nanotechnology in prostate cancer theranostic applications

Publisher : Journal of Nanoscience and Nanotechnology

High-Throughput Translational Medicine: Challenges and Solutions

Publisher : Systems Analysis of Human Multigene Disorders

Synthesis, Characterization of Polyurethanes and Polyurethane-Ureas Based on Zinc Salt of Mono(hydroxybutyl)Phthalate

Publisher : Journal of Macromolecular Science, Part-A; Pure and Applied Chemistry

A special issue on polymer conjugate based nanotherapeutics

Publisher : Journal of Biomedical Nanotechnology

STUDIES ON ZINC-CONTAINING POLYURETHANES AND POLYURETHANE-UREAS

Publisher : Journal of Macromolecular Science, Part A

Studies on Metal-containing Copolyurethanes

Publisher : Reactive and Functional Polymers

Autochthonous Blastomycosis of the Adrenal: First Case Report from Asia

Publisher : The American Journal of Tropical Medicine and Hygiene

Novel Chitin/nanosilica Composite Scaffolds for Bone Tissue Engineering Applications

Publisher : International Journal of Biological Macromolecules

Editorial.

Publisher : J Biomed Mater Res B Appl Biomater

Calcium-containing poly(urethane-urea)s: Synthesis, spectral, and thermal studies

Publisher : Journal of Polymer Science Part A: Polymer Chemistry

Tissue Engineering – Part A: Editorial

Publisher : Tissue Engineering – Part A

Phosphorous Containing Chitosan Beads for Controlled Oral Drug Delivery

Publisher : Journal of Bioactive and Compatible Polymers

New Synthesis Procedure of Phosphoryl Chitin

Publisher : Polymer Preprints,

Knock-down of DMY initiates female pathway in the genetic male medaka, Oryzias latipes

Publisher : Biochemical and biophysical research communications

Preparation of Silver Nanoparticles Incorporated Electrospun Polyurethane Nano-fibrous Mat for Wound Dressing

Publisher : Journal of Macromolecular Science, Part A: Pure and Applied Chemistry

Synthesis and Characterization of N‐methylenephenyl Phosphonic Chitosan

Publisher : Journal of Macromolecular Science, Part A

Sulfated Chitin and Chitosan as Novel Biomaterials

Publisher : International Journal of Biological Macromolecules

DMY gene induces male development in genetically female (XX) medaka fish

Publisher : Proceedings of the National Academy of Sciences

Hydroxyapatite-Reinforced Polyamide 6,6 Nanocomposites Through Melt Compounding

Publisher : International Journal of Polymeric Materials and Polymeric Biomaterials

XRD Studies of β-chitin from Squid Pen with Calcium Solvent

Publisher : International Journal of Biological Macromolecules

Synthesis of Phosphorylated Chitosan by Novel Method and its Characterization

Publisher : International Journal of Biological Macromolecules

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