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Dr. Arathi G.R. currently serves as Research Scientist at AMBC. She defended her Ph.D thesis titles on Mathematical modeling of neuronal circuit dynamics and physiological functions of rat cerebellum and basal ganglia, under the guidance of Dr. Shyam Diwakar (AMBC). Arathi completed her undergraduate and postgraduate studies in Bioinformatics from Mahatma Gandhi university (Kerala) and Amrita Vishwa vidyapeetham university respectively. Her undergraduate project dissertation on Systems biology approaches to the carbohydrate mechanism, Glycolysis. She has a master’s dissertation titled on Estimation of mutual information at mossy fiber-granule cell relay. During the tenure, she worked as a teaching assistant at Amrita School of Biotechnology. Currently she is working on the mathematical modeling of learning mechanisms in interconnected motor neuronal systems in the brain, this study allows the detailed exploration of learning, developing and forming memories. 

Publications 

Journals 

  1. Rajendran, A., Vijayan, A., Medini, C., Nair, B. And Diwakar, S. (2021) ‘Computational modeling of cerebellum granule neuron temporal responses for auditory and visual stimuli’, Int. J. Advanced Intelligence Paradigms, Vol. 18, No. 3, pp.356–372.
  2. Rajendran AG., Nuttaki C., Sasidharakurup H., Bodda S., Nair B., Diwakar S., and Cerebellum in neurological disorders: A review on the role of inter- connected neural circuits, j Neurol Stroke 6(2): 00196.

Book Chapter 

  1. Diwakar S, Nutakki C, Bodda S, Rajendran A, Vijayan A, Nair B. Mathematical Modeling of Cerebellar Granular Layer Neurons and Network Activity: Information Estimation, Population Behaviour and Robotic Abstractions, Springer INdAM series.

Conference Papers 

  1. Arathi Rajendran, Navya Ajith, Aiswarya Chandrabhanu Nambiar, Giovanni Naldi, Shyam Diwakar, Computational Modelling of Spiking in the Layer5 Projection Neurons of the mouse motor cortex, the fifth international conference on computing and network communication, December 18-20, 2023.
  2. Dathatreyan, G., Rajendran, A., Naldi, G., & Diwakar, S. (2023, April). Automated Reduction of Detailed Biophysical Cerebellar Neurons to Izhikevich Neurons. In International Symposium on Intelligent Informatics: Proceedings of ISI 2022 (pp. 109-121). Singapore: Springer Nature Singapore.
  3. Rajendran A., Sargurunathan KN.,Menon V.,Variyath S., Sai S.,Diwakar S., Computational Reconstructions of Extracellular Action Potentials and Local Field Potentials of a Rat Cerebellum using Point Neuron", Proceedings of Fourth International Conference on Computing and Network Communications (CoCoNet2020) , Chennai , India, October 14-17, 2020.
  4. Sasidharakurup H., Nutakki C., Rajendran A., Venugopal P., Sumon M., Navneethkumar L, Madhu H, Nair B, Diwakar S, Spectral correlations in speaker- listener behavior during a focused duo conversation using EEG, Proceedings of 2018 International conference of advances in computing, communication, and informatics (ICACCI 2018), Bangalore.
  5. Rajendran A., Abdulsalam A., Mohan D., Thazathepurayil J., Prabhat S., Nair B, Diwakar S. Trajectory tracking using a bio-inspired neural network for a low-cost robotic articulator. Proceedings of 2018 International conference of advances in computing, communication, and informatics (ICACCI 2018), Bangalore.
  6. Presannan A., Rajendran A.,Nair B., Diwakar S. Reproducing the firing properties of a cerebellum deep cerebellar nucleus with a multicompartmental morphologically realistic biophysical model. Proceedings of 2018 International conference of advances in computing, communication, and informatics (ICACCI 2018), Bangalore.
  7. Rajendran A.,Vijayan A.,Medini C., Nair B., Diwakar S., ‘Computational Modeling of Cerebellum Granule Neuron Temporal Responses for Auditory and Visual Stimuli’, Int. J. Advanced Intelligence Paradigms, Vol. , No. , pp., 2017.
  8. Rajendran A., Thankamani a., Nirmala N., Nair B., Diwakar s., Computational neuroscience of substantia nigra circuit and dopamine modulation during Parkinson’s disease, proceedings of 2017 international conference of advances in computing, communication, and informatics (ICACCI 2017), Manipal, India, Sep 13-16, 2017.
  9. Medini C, Rajendran A, Jijibai A, Nair B, Diwakar S, Computational characterization of cerebellum granule neuron responses to auditory and visual inputs, proceedings of 2016 international conference of advances in Computing, Communication, and Informatics (ICACCI 2016), Jaipur, India, Sep 21-24, 2016.
  10. Nair, M., Madhu, P., Mohan, V., Rajendran, A. G., Nair, B., & Diwakar, S. (2015, December). GPGPU implementation of information theoretic algorithms for the analysis of granular layer neurons. In 2015 International Conference on Computing and Network Communications (CoCoNet) (pp. 18-26). IEEE.

Posters 

  1. Analysis and Quantification of Neural Information Processing during Cerebellar Plasticity, International Symposium on Translational Neuroscience and XXXII annual conference of Indian Academy of Neuroscience, November 1- 3,2014, NIMHANS, Bengaluru.
  2. Parallelization of Cerebellar Granular Layer Circuitry Model for Physiological Predictions, International Symposium on Translational Neuroscience and XXXII annual conference of Indian Academy of Neuroscience, November 1-3,2014, NIMHANS, Bengaluru.
  3. Analyzing Mutual Information and Synaptic Efficacy at Mossy Fiber –Granule Cell Relay in Rat Cerebellum, Annual Conference of Indian Academy of Neurosciences, October 31-November 2, Punjab University, Chandigarh.
  4. Modelling and Parallelization of Cerebellar Microcircuit for Combinatorial Operations, XXXIV Annual Meeting of Indian Academy of Neurosciences, NBRC, Manesar.

Awards 

  1. Lalitha and RabindraNath Travel Fellowship for attending IAN (Indian Academy of Neurosciences) 2015 conference held at Punjab University from 31st October-2nd November 2015.

Earlier Affiliations 

  • Research Assistant, Virtual lab projects (13/01/2-14- 31-10-2017) 
  • Ph.D. research fellow, Amrita vishwa vidyapeetham, (01/11/2017-01-01-2019) 
  • Ph.D. research fellow, Amrita school of Biotechnology (01/02/2019-31-04-2022) 
  • Research Associate, Amrita Mind brain center, (01-/05/2022- 31/03/2024) 
  • Research Scientist, Amrita Mind brain center, (01-/04/2024- till now) 

Education 

  • BSc. Bioinformatics, from MES College for Advanced Studies, Aluva, Ernakulam. 
  • M.Sc. Bioinformatics, from Amrita School of Biotechnology, Kollam. 
  • Ph.D from Amrita Vishwa vidyapeetham. 

Teaching 

  • Introduction to C programming for MSc. Bioinformatic students. 
  • Mathematical modeling for MSc. Bioinformatics students. 
  • Computational Neuroscience for MSc Bioinformatics students. 
  • Biology for Engineers for B.Tech. students. 
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