The global prevalence of heterozygous familial hypercholestrolemia (FH)is estimated to be 1 in 250 with considerable regional differences .Identification of autosomal dominantly inherited FH presents an opportunity cascade screening and coronary artery disease prevention .Our observational cross sectional study aims to determine the genetic profile of patients who are clinically diagnosed to have familial hypercholestrolemia based on Dutch criteria.
We aim to do genetic studies in 225 patients who are clinically diagnosed to have FH. In the first set of 50 samples analysed 20-25% were found to have either monogenic variants or high polygenic score.
Department of Computer Science and I.T., School of Arts & Sciences, Kochi Campus
Good knowledge in Mathematics. Preferred candidates with M. Tech.
Assistant Professor,
Department of Computer Science and I.T.,
School of Arts & Sciences,
Amrita Vishwa Vidyapeetham, Kochi.
For admissions, please write to phd@amrita.edu.
The title of the email should include the thematic area you want to apply.