Back close

Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Start Date: Sunday, Mar 01,2009

School: School of Biotechnology

Funded by:Amrita Vishwa Vidyapeetham
Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Divergent oriented synthesis is a strategy which aims to the synthesis of compounds with diverse chemical structures. It is often an alternative to convergent synthesis or linear synthesis. With this intention, the diversity oriented synthesis was developed. In Phytochemistry laboratory our aims is to generate a library of bioactive oxygen heterocyclic compounds by first reacting with a easily available starting material to form set of intermediates, e.g. chalcones, 1,3-diketones.  The next target compounds are generated by suitable transformations of  intermediates, e.g. flavones, flavonols, flavanones, isoflavones and biflavones. This methodology quickly diverges to large numbers of different classes of compounds from simple starting materials. It is also efficient synthesis. The scheme methodology is given below.

diversity-bio-project

Some examples of  compounds synthesised are given below:

  1. chalcones
  2. dihydroflavonols
  3. flavones
  4. flavonol 
  5. isoflavones

Related Projects

Seabuckthorn – A Repository of Bioactive Phytochemicals
Seabuckthorn – A Repository of Bioactive Phytochemicals
Inventory of Vegetation with special reference to Medicinal and Aromatic Plants and Documentation of Traditional Knowledge – in the Walayar Valley, Western Ghats
Inventory of Vegetation with special reference to Medicinal and Aromatic Plants and Documentation of Traditional Knowledge – in the Walayar Valley, Western Ghats
Determination of Antibacterial Activity of Different Spices Against E.coli
Determination of Antibacterial Activity of Different Spices Against E.coli
Production, Purification and Application of Naringinase from soil isolates of Aspergillus spp
Production, Purification and Application of Naringinase from soil isolates of Aspergillus spp
Modelling the cerebellar information code in large-scale realistic circuits – Towards pharmacological predictions and robotic abstractions
Modelling the cerebellar information code in large-scale realistic circuits – Towards pharmacological predictions and robotic abstractions
Admissions Apply Now