Back close

Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Start Date: Sunday, Mar 01,2009

School: School of Biotechnology

Funded by:Amrita Vishwa Vidyapeetham
Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Divergent oriented synthesis is a strategy which aims to the synthesis of compounds with diverse chemical structures. It is often an alternative to convergent synthesis or linear synthesis. With this intention, the diversity oriented synthesis was developed. In Phytochemistry laboratory our aims is to generate a library of bioactive oxygen heterocyclic compounds by first reacting with a easily available starting material to form set of intermediates, e.g. chalcones, 1,3-diketones.  The next target compounds are generated by suitable transformations of  intermediates, e.g. flavones, flavonols, flavanones, isoflavones and biflavones. This methodology quickly diverges to large numbers of different classes of compounds from simple starting materials. It is also efficient synthesis. The scheme methodology is given below.

diversity-bio-project

Some examples of  compounds synthesised are given below:

  1. chalcones
  2. dihydroflavonols
  3. flavones
  4. flavonol 
  5. isoflavones

Related Projects

Production, Purification and Application of Naringinase from Aspergillus sp. Sec.Nigri
Production, Purification and Application of Naringinase from Aspergillus sp. Sec.Nigri
Purification of Fibronectin Using Gelatin-Polymer Conjugates
Purification of Fibronectin Using Gelatin-Polymer Conjugates
Mass spectrometry based proteomic characterization of carbonylated proteins as indicators of oxidative stress
Mass spectrometry based proteomic characterization of carbonylated proteins as indicators of oxidative stress
Development of chromatographic separation and detection techniques for natural products, as plant extracts, peptides, proteins and carbohydrates
Development of chromatographic separation and detection techniques for natural products, as plant extracts, peptides, proteins and carbohydrates
Computational Modelling and Prediction of Cerebellar Input Layer function, Timing and Plasticity for Understanding Neurophysiological Disorders
Computational Modelling and Prediction of Cerebellar Input Layer function, Timing and Plasticity for Understanding Neurophysiological Disorders
Admissions Apply Now