Publication

Abstract : A highly sensitive electrochemical sensor was fabricated using disposable pencile graphite electrode for the determination of cysteamine. Electrode characterization was done using scanning electron microscopy and X-Ray diffraction studies. The electrochemical properties of the PGE were studied using cyclic voltammetry and differential pulse voltammetric methods. The oxidation peak of cysteamine was observed at a potential of +0.446 V in 0.1 M NaOH and is attributed to the oxidation of the cysteamine to the dimer cystamine. The fabricated sensor exhibited a linear dynamic range of 10µM-110µM. The sensitivity was found to be 0.4077 µA/µM/cm2, with a detection limit of 4µM. The proposed electrochemical sensor was used for the determination of cysteamine in urine samples with high selectivity..