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Dr. Debnarayan Dutta

Head of Department, Department of Radiation Oncology, School of Medicine, Kochi | Professor, Department of Radiation Oncology, School of Medicine, Kochi

Qualification: MBBS, MD (Radiation Oncology)

debnarayan@aims.amrita.edu

Bio

Dr. Debnarayan Dutta is a distinguished figure in the field of Radiation Oncology, currently serving as the Clinical Professor & Head of the Department of Radiation Oncology at Amrita School of Medicine, Kochi. With a career spanning over two decades, Dr. Dutta has amassed extensive experience and expertise in the treatment of cancer through radiation therapy, particularly specialising in advanced techniques such as CyberKnife and stereotactic radiosurgery.

Publications

Journal Article

Year : 2024

Validation of Combs prognostic scoring system in Indian recurrent glioma patients treated with re-radiation

Cite this Research Publication : Dutta D, Jose M, Kalavagunta S, Annex H. "Validation of Combs prognostic scoring system in Indian recurrent glioma patients treated with re-radiation". Jan 2024, Radiation Oncology Journal, 2024;42(1):32-42, DOI: 10.3857/roj.2023.00542

Publisher : Radiation Oncology Journal

Year : 2024

Audit of presentation, primary site and pattern of treatment in 778 Indian patients with brain metastasis in 15 years (2007-2022)

Cite this Research Publication : Dutta D, Surendran HP, Kalavagunta S, Sasidharan A, Narmadha MP. "Audit of presentation, primary site and pattern of treatment in 778 Indian patients with brain metastasis in 15 years (2007-2022)". Neurology India, 2024 (In Press)

Publisher : Neurology India (In Press)

Year : 2023

Efficacy of memantine in Preventing neurocognitive dysfunction induced by radiation therapy in patients with brain metastases: A systematic review of clinical trials

Cite this Research Publication : Surendran HP, Sah SK, Louis DM, Kalavagunta S, Poornachary NM, Joy SC, Dutta D. "Efficacy of memantine in preventing neurocognitive dysfunction induced by radiation therapy in patients with brain metastases: A systematic review of clinical trials," Seminars in Oncology, 2023 Jun-Oct;50(3-5):113-122. doi: 10.1053/j.seminoncol.2023.09.004. Epub 2023 Sep 16. PMID: 37775420.

Publisher : Seminars in Oncology

Year : 2023

Extramedullary plasmacytoma of the larynx -Case report

Cite this Research Publication : Gupte A, Sasidharan A, Nair A, Dutta D. "Extramedullary plasmacytoma of the larynx -Case report," September 2023. Journal of Cancer Research and Therapeutics 20(1):p 493-495, Jan–Mar 2024. | DOI: 10.4103/jcrt.JCRT_1640_20

Publisher : Journal of Cancer Research and Therapeutics

Year : 2023

2023 Update of Indian National Association for Study of the Liver Consensus on Management of Intermediate and Advanced Hepatocellular Carcinoma: The Puri III Recommendations

Cite this Research Publication : Kumar A, Acharya SK, Singh SP, Duseja A, Madan K, Shukla A, Arora A, Anand AC, Bahl A, Soin AS, Sirohi B, Dutta D, Jothimani D, Panda D, Saini G, Varghese J, Kumar K, Premkumar M, Panigrahi MK, Wadhawan M, Sahu MK, Rela M, Kalra N, Rao PN, Puri P, Bhangui P, Kar P, Shah SR, Baijal SS, Shalimar, Paul SB, Gamanagatti S, Gupta S, Taneja S, Saraswat VA, Chawla YK., "2023 Update of Indian National Association for Study of the Liver Consensus on Management of Intermediate and Advanced Hepatocellular Carcinoma: The Puri III Recommendations," J Clin Exp Hepatol. 2024 Jan-Feb;14(1):101269. doi: 10.1016/j.jceh.2023.08.005. Epub 2023 Aug 19. PMID: 38107186; PMCID: PMC10724697.

Publisher : Journal of Clinical and Experimental Hepatology

Year : 2023

Prospective Evaluation of Response to Treatment, Survival Functions, Recurrence Pattern and Toxicity Profile in Indian Patients with Oligo-Brain Metastasis Treated with Only SRS

Cite this Research Publication : Dutta D, Reddy SK, Kamath RK, Sreenija Y, Nair H, Sashidharan A, Remesan Nair RA, Pushpuja KU, Kannan R, Edappattu A, Haridas NK, Jose WM, Keechilat P. "Prospective Evaluation of Response to Treatment, Survival Functions, Recurrence Pattern and Toxicity Profile in Indian Patients with Oligo-Brain Metastasis Treated with Only SRS". Neurology India, 2023 Jan-Feb;71(1):62-71. doi: 10.4103/0028-3886.370470. PMID: 36861576.

Publisher : Neurology India

Year : 2023

Hypofractionated Radiotherapy for Stage I Squamous Cell Carcinoma Glottis: An Experience with 60Gy in 20 Fractions

Cite this Research Publication : Pushpaja KU, Nair AR, Mazhoor SN, Lakshmi JS, Dutta D. "Hypofractionated Radiotherapy for Stage I Squamous Cell Carcinoma Glottis: An Experience with 60Gy in 20 Fraction," October 2023; Iranian Journal of Medical Physics Volume 20(Issue 4):226-232: DOI: 10.22038/IJMP.2022.62774.2073

Publisher : Iranian Journal of Medical Physics

Year : 2022

Case Report Role of Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography in Detection of Portal Vein Tumor Thrombosis in Hepatocellular Carcinoma

Cite this Research Publication : Yarlagadda S, Sasidharan A, Sundaram S, Dutta D., "Case Report Role of Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography in Detection of Portal Vein Tumor Thrombosis in Hepatocellular Carcinoma". Journal of Gastroenterology & Hepatology Reports., January 2022. DOI: 10.47363/JGHR/2022(3)129

Publisher : Journal of Gastroenterology & Hepatology Reports.

Year : 2022

Preservation of cognitive function after brain irradiation

Cite this Research Publication : Surendran HP, Narmadha MP, Kalavagunta S, Sasidharan A, Dutta D. "Preservation of cognitive function after brain irradiation," Journal of Oncology Pharmacy Practice, 2022 Jul;28(5):1182-1188. doi: 10.1177/10781552221077037. Epub 2022 Feb 3. PMID: 35112915.

Publisher : Journal of Oncology Pharmacy Practice

Year : 2022

Abnormal olfactory perception during stereotactic radiation therapy using Cyberknife for primary brain tumor: A case study

Cite this Research Publication : Verma P, Reddy SK, Bhaskaran P, Haridas AE, Dutta D. "Abnormal olfactory perception during stereotactic radiation therapy using Cyberknife for primary brain tumor: A case study". Journal of Radiosurgery & SBRT, 2022;8(2):147-150. PMID: 36275127; PMCID: PMC9489080.

Publisher : Journal of Radiosurgery & SBRT

Year : 2021

Editorial: Novel Applications of Stereotactic Body Radiotherapy (SBRT)

Cite this Research Publication : Kotecha R, Dutta D, Jalali R, Muacevic A. "Editorial: Novel Applications of Stereotactic Body Radiotherapy (SBRT)". Frontiers in Oncology, 2021 Sep 3;11:760078. doi: 10.3389/fonc.2021.760078. PMID: 34540704; PMCID: PMC8448417.

Publisher : Frontiers in Oncology

Year : 2021

A review on radiation induced nausea and vomiting: “Current management strategies and prominence of radio sensitizers”

Cite this Research Publication : Vijayan M, Joseph S, James E, Dutta D. "A review on radiation induced nausea and vomiting: Current management strategies and prominence of radio sensitizers", Journal of Oncology Pharmacy Practice, 2021 Jul;27(5):1061-1072. doi: 10.1177/10781552211011539. Epub 2021 May 4. Erratum in: J Oncol Pharm Pract. 2022 Dec;28(8):1936. PMID: 33947288.

Publisher : Journal of Oncology Pharmacy Practice

Year : 2021

Unusual presentation of an extrahepatic migration of a fiducial implanted for stereotactic body radiotherapy

Cite this Research Publication : Jose M, Pottikyal GS, Sasidharan A, Reddy SK, Haridas AE, Dutta D, "Unusual presentation of an extrahepatic migration of a fiducial implanted for stereotactic body radiotherapy", Journal of Radiosurgery & SBRT, 2021;7(3):257-260. PMID: 33898091; PMCID: PMC8055242

Year : 2021

Hepatocellular carcinoma patients with portal vein thrombosis treated with robotic radiosurgery: Interim results of a prospective study

Cite this Research Publication : Dutta D, Tatineni T, Yarlagadda S, Gupte A, Reddy SK, Madhavan R, Nair H, Sasidharan A, Kannan R, Pottayil SG, Holla R, Sudhindran S., "Hepatocellular carcinoma patients with portal vein thrombosis treated with robotic radiosurgery: Interim results of a prospective study". Indian Journal of Gastroenterology, 2021 Aug;40(4):389-401. doi: 10.1007/s12664-021-01172-w. Epub 2021 Oct 25. PMID: 34694581.

Publisher : Indian Journal of Gastroenterology

Year : 2021

Relevance of Child Pugh Scoring System as Inclusion Criteria in Hepatocellular Carcinoma Management

Cite this Research Publication : Dutta D., "Relevance of Child Pugh Scoring System as Inclusion Criteria in Hepatocellular Carcinoma Management," Japanese Journal of Gastroenterology and Hepatology, 2021; V6(17): 1-3.

Publisher : Japanese Journal of Gastroenterology and Hepatology

Year : 2020

Effect of Arg399Gln single-nucleotide polymorphism in XRCC1 gene on survival rate of Indian squamous cell head-and-neck cancer patients

Cite this Research Publication : Dutta D, Abarna R, Shubham M, Subbiah K, Duraisamy S, Chinnusamy R, Anbalagan M., "Effect of Arg399Gln single-nucleotide polymorphism in XRCC1 gene on survival rate of Indian squamous cell head-and-neck cancer patients," Journal of Cancer Research and Therapeutics, 2020 Apr-Jun;16(3):551-558. doi: 10.4103/jcrt.JCRT_476_18. PMID: 32719266.

Publisher : Journal of Cancer Research and Therapeutics

Year : 2020

Hippocampal radiotherapy dose constraints for predicting long-term neurocognitive outcomes: mature data from a prospective trial in young patients with brain tumors

Cite this Research Publication : Goda JS, Dutta D, Krishna U, Goswami S, Kothavade V, Kannan S, Maitre M, Bano N, Gupta T, Jalali R. "Hippocampal radiotherapy dose constraints for predicting long-term neurocognitive outcomes: mature data from a prospective trial in young patients with brain tumors". Neuro-Oncology, 2020 Nov 26;22(11):1677-1685. doi: 10.1093/neuonc/noaa076. PMID: 32227185; PMCID: PMC7690355.

Publisher : Neuro-Oncology

Year : 2020

Prospective evaluation of fiducial marker placement quality and toxicity in liver CyberKnife stereotactic body radiotherapy

Cite this Research Publication : Dutta D, Kataki KJ, George S, Reddy SK, Sashidharan A, Kannan R, Madhavan R, Nair H, Tatineni T, Holla R., "Prospective evaluation of fiducial marker placement quality and toxicity in liver CyberKnife stereotactic body radiotherapy," Radiation Oncology Journal, 2020 Dec;38(4):253-261. doi: 10.3857/roj.2020.00472. Epub 2020 Nov 30. PMID: 33249803; PMCID: PMC7785839.

Publisher : Radiation Oncology Journal

Year : 2019

Dose-Constraint Model to Predict Neuroendocrine Dysfunction in Young Patients With Brain Tumors: Data From a Prospective Study

Cite this Research Publication : Jalali R, Maitre M, Gupta T, Goda JS, Shah N, Krishna U, Swamidas J, Kannan S, Dutta D, Sarin R., "Dose-Constraint Model to Predict Neuroendocrine Dysfunction in Young Patients With Brain Tumors: Data From a Prospective Study," Practical Radiation Oncology, 2019 Jul-Aug;9(4):e362-e371, doi: 10.1016/j.prro.2019.02.011, Epub 2019 Feb 28, PMID: 30826479.

Publisher : Practical Radiation Oncology

Year : 2019

Case Report on Stereotactic Body Radiation Therapy for Locally Recurrent Renal Cell Carcinoma after Partial Nephrectomy in a Patient with Single Kidney

Cite this Research Publication : Kataki KJ, Gupte A, Madhavan R, Beena K, Dutta D, Holla R, Kalita M. "Case report on stereotactic body radiation therapy for locally recurrent renal cell carcinoma after partial nephrectomy in a patient with single kidney". South Asian J Cancer. 2019 Apr-Jun;8(2):135-136. doi: 10.4103/sajc.sajc_7_19. PMID: 31069199; PMCID: PMC6498713.

Publisher : South Asian J Cancer

Year : 2018

Identification of novel heterozygous Apex 1 gene variant (Glu87Gln) in patients with head and neck cancer of Indian origin

Cite this Research Publication : Abarna R, Dutta D, Sneha P, George Priya Doss C, Anbalagan M., "Identification of novel heterozygous Apex 1 gene variant (Glu87Gln) in patients with head and neck cancer of Indian origin," Journal of Cellular Biochemistry, 2018 Nov;119(11):8851-8861. doi: 10.1002/jcb.27138. Epub 2018 Aug 4. PMID: 30076617.

Publisher : Journal of Cellular Biochemistry

Year : 2018

Cholangiocarcinoma Treatment with Synchrony-based Robotic Radiosurgery System: Tracking Options

Cite this Research Publication : Debnarayan Dutta, Menon, A., Abraham, A. George, Madhavan, R., Nair, H., Shalet, P. G., Jishan, J., and Holla, R., “Cholangiocarcinoma Treatment with Synchrony-based Robotic Radiosurgery System: Tracking Options”, J Radiosurg SBRT, vol. 5, no. 4, pp. 335-340, 2018.

Publisher : J Radiosurg SBRT .

Conference Paper

Year : 2022

Efficacy of Memantine in Preventing Neurocognitive Dysfunction Induced By Radiation Therapy in Patients with Brain Metastases: A Systematic Review of Clinical Trials

Cite this Research Publication : Surendran HP, Dutta D, Sah SK, Louis DM. "Efficacy of Memantine in Preventing Neurocognitive Dysfunction Induced By Radiation Therapy in Patients with Brain Metastases: A Systematic Review of Clinical Trials".  ISPOR-2022, July 2022. Value in Health 25(7) (CO104). DOI: 10.1016/j.jval.2022.04.200.

Publisher : ISPOR-2022

Book Chapter

Year : 2022

Radiation Induced Liver Toxicity

Cite this Research Publication : Dutta D, Yarlagadda S. "Radiation Induced Liver Toxicity". In book: Hepatotoxicity, Intech Open, July 2022, DOI: 10.5772/intechopen.105410.

Publisher : Intech Open

Area of Expertise
  • Radiosurgery
  • Stereotactic Body Radiation Therapy (SBRT)
  • Neurooncology
Languages Known
  • English
  • Hindi
  • Bangla
Work Experience
  • 2017 – Onwards: Professor & Head, Radiation Oncology & Cyberknife In-Charge, Amrita School of Medicine, Kochi
  • 2010 – 2016: Senior Consultant, Radiation Oncology, Apollo Cancer Hospital, Chennai
  • 2008 – 2010: Senior Registrar in Radiation Oncology, Tata Memorial Hospital, Mumbai
Awards & Achievements
  • ASCO merit award at Chicago in 2008
  • Participant at ‘Hoshino Young Investigator award’ at Yokahama 2009
  • Neucletron Fellowship award in AROICON 2010 at Patna, India
  • ‘Presidential award for Best Clinical researcher’ for the year 2024 by Indian Society of Neurooncooogy (ISNO)
  • Introduced CyberKnife Radiosurgery facility in India in the year 2010 at Apollo Specialty Cancer Hospital, Chennai. At present, in-charge of CyberKnife radiosurgery facility at Amrita Institute, Kochi and have treated more than 1500 patients at Kochi with radiosurgery
  • 110 Indexed publication, three book chapters, reviewer and co-editor of multiple journals
  • Invited speaker about CyberKnife / Radiosurgery and radiation oncology in more than 200 meetings in India and abroad.
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