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Dr. Ullas Mony

Assistant Professor, Amrita School of Nanosciences and Molecular Medicine, Kochi

Qualification: Ph.D
ullas19351@aims.amrita.edu

Bio

Dr. Mony received his Ph.D (Haematology) from The University of Nottingham, UK. He worked on targeting of minimal residual disease in Acute Myeloid Leukemia. He developed a ‘niche-like’ condition for testing the chemosensitivity of leukemic stem and progenitor cells. Dr. Mony had identified multiple signaling pathways involved in the survival of leukemic stem and progenitor cells. He received prestigious awards such as Overseas Research Scholarship and Developing Solutions Scholarship (University of Nottingham, UK). He was also a recipient of the British Association of Cancer Research student award during his Ph.D time. He had his postdoctoral training as a senior fellow in a collaborative research programme at Memorial Sloan-Kettering Cancer Centre, USA, and Broad Institute of MIT and Harvard, USA. His expertise and training includes hemato-oncology, tumor microenvironment, preclinical drug discovery (small molecules), pre-clinical mice model development of cancers, and induced pluripotent stem cells (iPSC). He is trained and certified in rodent major surgical procedures from Cornell University, USA, and Memorial Sloan-Kettering Cancer Center, USA. He got trained in iPSC generation and differentiation from The University of Queensland and Monash University, Australia.

Dr. Mony joined Amrita Center for Nanosciences and Molecular Medicine as Assistant Professor in April 2009. Dr. Mony’s Stem cell and translational lab is focused mainly in two areas. Firstly in finding out the molecular heterogeneity and identification of novel targets in AML cells treated with various therapeutic agents, and secondly, in the generation and differentiation of iPS cells for drug screening and disease modeling applications. He is also heading the advanced immunohematology and flowcytometry facility of the center for disease diagnosis and research. His publications are in major international journals of repute such as Leukemia, Blood, Haematologica, Molecular Oncology etc.

His research interest includes Leukemic Stem Cells/Acute Myeloid Leukemia and targeting, Tumor microenvironment, Immunotherapy, Pre-clinical mice model development, proteomics and iPSC.

 

Publications

Journal Article

Year : 2021

Combinatorial effect of plasma treatment, fiber alignment and fiber scale of poly (ε-caprolactone)/collagen multiscale fibers in inducing tenogenesis in non-tenogenic media

Cite this Research Publication : Deepthi Sankar, Ullas Mony, and Dr. Jayakumar Rangasamy, “Combinatorial effect of plasma treatment, fiber alignment and fiber scale of poly (ε-caprolactone)/collagen multiscale fibers in inducing tenogenesis in non-tenogenic media”, Materials Science and Engineering C, vol. 127, p. 112206, 2021.

Publisher : Materials Science and Engineering C

Year : 2021

Hydrogels: A potential platform for induced pluripotent stem cell culture and differentiation

Cite this Research Publication : M. R. Poorna, Dr. Jayakumar Rangasamy, Jyh -PingChen, and Ullas Mony, “Hydrogels: A potential platform for induced pluripotent stem cell culture and differentiation”, Colloids and Surfaces B: Biointerfaces, vol. 207, p. 111991, 2021.

Publisher : Colloids and Surfaces B: Biointerfaces,

Year : 2021

Vasoconstrictor and coagulation activator entrapped chitosan based composite hydrogel for rapid bleeding control

Cite this Research Publication : N. M. Sundaram, Ullas Mony, Dr. Praveen Varma, and Dr. Jayakumar Rangasamy, “Vasoconstrictor and coagulation activator entrapped chitosan based composite hydrogel for rapid bleeding control”, Carbohydrate Polymers, vol. 258, 2021.

Publisher : Carbohydrate Polymers

Year : 2021

Development and evaluation of plumbagin loaded chitin hydrogel for the treatment of skin cancer

Cite this Research Publication : Akanksha Nair, Sreeja C. Nair, Asoke Banerji, Dr. Raja Biswas, and Ullas Mony, “Development and evaluation of plumbagin loaded chitin hydrogel for the treatment of skin cancer”, Journal of Drug Delivery Science and Technology, vol. 66, p. 102804, 2021.

Publisher : Journal of Drug Delivery Science and Technology

Year : 2020

Differentiation of induced pluripotent stem cells to hepatocyte-like cells on cellulose nanofibril substrate

Cite this Research Publication : M. R. Poorna, Sudhindran, S., Thampi, M. V., and Dr. Ullas Mony, “Differentiation of induced pluripotent stem cells to hepatocyte-like cells on cellulose nanofibril substrate.”, Colloids Surf B Biointerfaces, p. 111466, 2020.

Publisher : Colloids Surf B Biointerfaces, p.111466 (2020)

Year : 2020

Human Adipose Tissue Derivatives as a Potent Native Biomaterial for Tissue Regenerative Therapies

Cite this Research Publication : S. S. Sharath, Ramu, J., Shantikumar V Nair, Iyer, S., Dr. Ullas Mony, and Dr. Jayakumar Rangasamy, “Human Adipose Tissue Derivatives as a Potent Native Biomaterial for Tissue Regenerative Therapies”, Tissue Engineering and Regenerative Medicine, vol. 17, no. 2, pp. 123-140, 2020.

Publisher : Tissue Engineering and Regenerative Medicine

Year : 2020

Extracellular Trap by Blood Cells: Clinical Implications

Cite this Research Publication : R. J. Nija, Sanju, S., Sidharthan, N., and Dr. Ullas Mony, “Extracellular Trap by Blood Cells: Clinical Implications”, ) Tissue Engineering and Regenerative Medicine, vol. 17, no. 2, pp. 141-153, 2020.

Publisher : Tissue Engineering and Regenerative Medicine

Year : 2020

Innate Lymphoid Cells: Potent Early Mediators of the Host Immune Response During Sepsis

Cite this Research Publication : Theertha M., S., S., Priya, V. V., Jain, P., Dr. Praveen Varma, and Dr. Ullas Mony, “Innate Lymphoid Cells: Potent Early Mediators of the Host Immune Response During Sepsis”, Cellular and Molecular Immunology, 2020.

Publisher : Cellular and Molecular Immunology

Year : 2017

Tri-Layered Nanocomposite Hydrogel Scaffold for the Concurrent Regeneration of Cementum, Periodontal Ligament, and Alveolar Bone.

Cite this Research Publication : S. Sowmya, Mony, U., Jayachandran, P., Reshma, S., R Kumar, A., Arzate, H., Nair, S. V., and Jayakumar, R., “Tri-Layered Nanocomposite Hydrogel Scaffold for the Concurrent Regeneration of Cementum, Periodontal Ligament, and Alveolar Bone.”, Adv Healthc Mater, vol. 6, no. 7, 2017.

Publisher : Advanced Healthcare Materials

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