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Dr-Jayalekshmi-H_asst-professor_biotechnology_amritauniversity_amritapuri

Dr. Jayalekshmi H

Associate Professor in the School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri

Qualification: MPhil, MSc, Ph.D
jayalekshmih@am.amrita.edu
Scholar

Bio Publications Education Professional Work Experience Teaching Participation in Conferences and Workshops Awards and Recognitions
Bio

Dr. Jayalekshmi H. currently serves as Associate Professor at the School of Biotechnology. She received her M. Phil. in Microbiology, Bharathidasan University, Tamil Nadu, 2007. She was also conferred M. Sc. Microbiology, Kasturba Medical College, Manipal University, Manipal in 1999.

Publications

Journal Article

Year : 2021

A Novel N4-Like Bacteriophage Isolated from a Wastewater Source in South India with Activity against Several Multidrug-Resistant Clinical Pseudomonas aeruginosa Isolates

Cite this Research Publication : Nitasha D. Menon, Megha S. Kumar, T. G. Satheesh Babu, Sucharita Bose, Gayathri Vijayakumar, Manasi Baswe, Meghna Chatterjee, Jovita Rowena D’Silva, Kavya Shetty, Jayalekshmi Haripriyan, Anil Kumar, Samitha Nair, Priyanka Somanath, Bipin G. Nair, Victor Nizet, Geetha B. Kumar "A Novel N4-Like Bacteriophage Isolated from a Wastewater Source in South India with Activity against Several Multidrug-Resistant Clinical Pseudomonas aeruginosa Isolates",

Publisher : mSphere

Year : 2018

Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa.

Cite this Research Publication : Jayalekshmi H., Omanakuttan, A., Menon, N. D., Muralidharan Vanuopadath, Nair, S. Sadasivan, Corriden, R., Nair, B. G., Nizet, V., and Kumar, G. B., “Clove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa.”, Sci Rep, vol. 8, no. 1, p. 3437, 2018.

Publisher : Scientific reports

Year : 2016

Clove Bud Oil Reduces Kynurenine and Inhibits pqs A Gene Expression in P. Aeruginosa

Cite this Research Publication : Jayalekshmi H., A. Omanakuttan, N. Pandurangan, V. S. Vargis, M. Maneesh, Dr. Bipin G. Nair, and Geetha B. Kumar, “Clove Bud Oil Reduces Kynurenine and Inhibits pqs A Gene Expression in P. Aeruginosa”, Applied microbiology and biotechnology, vol. 100, no. 8, pp. 3681-3692, 2016

Publisher : Applied microbiology and biotechnology

Year : 2009

Radio Frequency Electromagnetic Radiation (RF-EMR) from GSM (0.9/1.8 GHz) Mobile Phones Induces Oxidative Stress and Reduces Sperm Motility in Rats

Cite this Research Publication : M. Mailankot, Kunnath, A. P., Jayalekshmi H., Koduru, B., and Valsalan, R., “Radio Frequency Electromagnetic Radiation (RF-EMR) from GSM (0.9/1.8 GHz) Mobile Phones Induces Oxidative Stress and Reduces Sperm Motility in Rats”, Clinics, vol. 64, pp. 561–565, 2009.

Publisher : Clinics

Year : 2009

Effect of Alpha-Tocopherol Supplementation on Renal Oxidative Stress and Na+/K+-Adenosine Triphosphatase in Ethanol Treated Wistar Rats.

Cite this Research Publication : M. Mailankot, Jayalekshmi H., Chakrabarti, A., Alang, N., and Vasudevan, D. M., “Effect of Alpha-Tocopherol Supplementation on Renal Oxidative Stress and Na+/K+-Adenosine Triphosphatase in Ethanol Treated Wistar Rats.”, Indian journal of experimental biology, vol. 47, pp. 608–610, 2009.

Publisher : Indian journal of experimental biology

Year : 2006

Role of Reactive Oxygen Species and Antioxidants on Pathophysiology of Male Reproduction

Cite this Research Publication : M. Maneesh and Jayalekshmi H., “Role of Reactive Oxygen Species and Antioxidants on Pathophysiology of Male Reproduction”, Indian Journal of Clinical Biochemistry, vol. 21, pp. 80–89, 2006.

Publisher : Indian Journal of Clinical Biochemistry

Year : 2006

Impaired Hypothalamic-Pituitary-Gonadal Axis Function In Men With Diabetes Mellitus

Cite this Research Publication : M. Maneesh, Jayalekshmi H., Singh, T. A., and Chakrabarti, A., “Impaired Hypothalamic-Pituitary-Gonadal Axis Function In Men With Diabetes Mellitus”, Indian journal of clinical biochemistry, vol. 21, pp. 165–168, 2006.

Publisher : Indian journal of clinical biochemistry

Year : 2006

Antioxidants as Therapeutical Agents for Male Infertility.

Cite this Research Publication : M. Maneesh and Jayalekshmi H., “Antioxidants as Therapeutical Agents for Male Infertility. ”, Journal International Medical Sciences Academy , 2006.

Publisher : Journal International Medical Sciences Academy

Year : 2005

Role of Oxidative Stress in Ethanol Induced Germ Cell Apoptosis—an Experimental Study in Rats

Cite this Research Publication : M. Maneesh, Jayalekshmi H., Dutta, S., Chakrabarti, A., and Dr. Damodaran Vasudevan, “Role of Oxidative Stress in Ethanol Induced Germ Cell Apoptosis—an Experimental Study in Rats”, Indian Journal of Clinical Biochemistry, vol. 20, pp. 62–67, 2005.

Publisher : Indian Journal of Clinical Biochemistry, Springer

Year : 2005

Evidence for Oxidative Stress in Osteoarthritis

Cite this Research Publication : M. Maneesh, Jayalekshmi H., Suma, T., Chatterjee, S., Chakrabarti, A., and Singh, T. A., “Evidence for Oxidative Stress in Osteoarthritis”, Indian journal of clinical Biochemistry, vol. 20, pp. 129–130, 2005.

Publisher : Springer

Year : 2005

Effect of Chronic Ethanol Administration on Testicular Antioxidant System and Steroidogenic Enzyme Activity in Ratsc

Cite this Research Publication : M. Maneesh, Jayalekshmi H., Dutta, S., Chakrabarti, A., and Dr. Damodaran Vasudevan, “Effect of Chronic Ethanol Administration on Testicular Antioxidant System and Steroidogenic Enzyme Activity in Ratsc”, Indian J Exp Biol, vol. 43, pp. 445–449, 2005.


Publisher : Indian J Exp Biol,

Year : 2005

Effect of Ascorbic Acid, Alpha-Tocopherol, Lecithin and L-ornithine-L-aspartate on Ethanol Induced Hypoproteinemia and Hyperlipidemia in Rats

Cite this Research Publication : M. Maneesh and Jayalekshmi H., “Effect of Ascorbic Acid, Alpha-Tocopherol, Lecithin and L-ornithine-L-aspartate on Ethanol Induced Hypoproteinemia and Hyperlipidemia in Rats”, Indian journal of physiology and pharmacology, vol. 49, p. 422, 2005.

Publisher : Indian Journal of Physiology and Pharmacology

Conference Proceedings

Year : 2020

Essential oils modulate antibiotic mediated persister cell formation of P. aeruginosa

Cite this Research Publication : Jayalekshmi H., “Essential oils modulate antibiotic mediated persister cell formation of P. aeruginosa”, International Webinar on Phytochemistry 2020’ organized by Kerala Academy of Sciences. 2020.

Publisher : Kerala Academy of Sciences

Year : 2019

Combinatorial effect of garlic essential oil and Tetracycline against P. aeruginosa biofilm

Cite this Research Publication : Jayalekshmi H., “Combinatorial effect of garlic essential oil and Tetracycline against P. aeruginosa biofilm”, Proceedings of Biospectrum -2019; International Conference on Advances in Food and Industrial Biotechnology. 2019.

Publisher : Proceedings of Biospectrum -2019; International Conference on Advances in Food and Industrial Biotechnology

Year : 2017

Quorum Sensing Inhibitors Modulate Persister Cell Formation of Pseudomonas Aeruginosa

Cite this Research Publication : Jayalekshmi H., “Quorum Sensing Inhibitors Modulate Persister Cell Formation of Pseudomonas Aeruginosa”, Proceedings of 27th Swadeshi Science Congress. 2017. 2017.

Publisher : Proceedings of 27th Swadeshi Science Congress. 2017

Year : 2016

Preparation and Characterisation of Clove Bud Essential Oil Nanoemulsion : Investigation of its Antibiofilm Activity

Cite this Research Publication : Jayalekshmi H., “Preparation and Characterisation of Clove Bud Essential Oil Nanoemulsion : Investigation of its Antibiofilm Activity”, NextGen Genomics, Biology, Bioinformatics and Technologies (NGBT) Conference. 2016.

Publisher : NextGen Genomics, Biology, Bioinformatics and Technologies (NGBT) Conference

Year : 2015

Combinatorial Effect of D-amino Acids and Tetracycline Against P. Aeruginosa Biofilm

Cite this Research Publication : Jayalekshmi H., “Combinatorial Effect of D-amino Acids and Tetracycline Against P. Aeruginosa Biofilm”, Kerala Science congress . 2015. 2015.

Publisher : Kerala Science congress . 2015

Year : 2015

Antibiofilm Activity of Biosurfactants from Bacterial Strains Isolated from Oil Contaminated Soil and Sewage.

Cite this Research Publication : Jayalekshmi H., Geeta Kumar, and Dr. Bipin G. Nair, “Antibiofilm Activity of Biosurfactants from Bacterial Strains Isolated from Oil Contaminated Soil and Sewage.”, International conference-NHBT 2015. 2015

Publisher : International conference-NHBT 2015

Year : 2013

Effect of Mangroves Extracts on Quorum Sensing and Biofilm Formation in S.aureus and P.aeruginosa.

Cite this Research Publication : Jayalekshmi H., “Effect of Mangroves Extracts on Quorum Sensing and Biofilm Formation in S.aureus and P.aeruginosa.”, Amrita Bioquest. Kollam,Kerala, 2013.

Publisher : Amrita Bioquest

Year : 2011

Screening of Dietary Substances: New Blockade Strategy on Quorum Sensing.

Cite this Research Publication : M. Dhaneesha, D. Pai, A., and Jayalekshmi H., “Screening of Dietary Substances: New Blockade Strategy on Quorum Sensing. ”, 98th Indian Science Congress . SRM University, Chennai, 2011.

Publisher : SRM University

Year : 2011

Effect of Plant Essential Oils on Biofilm Formation and Adherence of Multidrug Resistant Staphylococcus aureus.

Cite this Research Publication : Jayalekshmi H., Sree, P. D., and Nair, B. G., “Effect of Plant Essential Oils on Biofilm Formation and Adherence of Multidrug Resistant Staphylococcus aureus.”, Proceedings of International Conference on New Horizons in Biotechnology (NHBT-2011). SRM University, Chennai , 2011.

Publisher : Proceedings of International Conference on New Horizons in Biotechnology (NHBT-2011)

Year : 2011

Effect of Clove Bud Essential Oil on Quorum Sensing Virulence Factors of P.aeruginosa.

Cite this Research Publication : Jayalekshmi H., “Effect of Clove Bud Essential Oil on Quorum Sensing Virulence Factors of P.aeruginosa. ”, BG.International Conference on New Horizons in Biotechnology, . Thiruvananthapuram,Kerala, 2011.

Publisher : BG.International Conference on New Horizons in Biotechnology,

Year : 2008

Effect of Chronic Ethanol Administration on Testicular Antioxidant System and Steriodegic Enzyme Activity in Rats and its Reversal with Ascorbic Acid

Cite this Research Publication : Jayalekshmi H., S, D., A, C., M, M., and DM, V., “Effect of Chronic Ethanol Administration on Testicular Antioxidant System and Steriodegic Enzyme Activity in Rats and its Reversal with Ascorbic Acid”, National conference of the Association of Physiologists & Pharmacologists of India. Kasturba Medical College, Mangalore, 2008.

Publisher : National conference of the Association of Physiologists Pharmacologists of India

Education
  • Ph. D., Amrita Vishwa Vidyapeetham
  • M. Phil. (Microbiology), Bharathidasan University, Tamil Nadu.
  • M. Sc. (Medical Microbiology), Kasturba Medical College, Manipal University, Karnataka
  • B. Sc. (Zoology), Kerala University, Kerala

Professional Work Experience
  • Senior Lecturer in Amrita School of Biotechnology
  • Lecturer in Amrita School of Biotechnology
  • Senior Research Fellow (CSIR funded project) in Sikkim Manipal Institute of Medical Sciences, Sikkim Manipal University, Gangtok, Sikkim.
  • Senior Research Fellow (ICAR funded project), Kerala Veterinary and Animal Science University, Thrissur, Kerala.
  • Microbiologist, Amrita Institute of Medical Sciences, Kochi, Kerala.
Teaching
  • MIC411/Bacterial and Viral Pathogenesis/4 Credits/ M. Sc Microbiology/Semester 2
  • MIC310/ Medical Bacteriology / 3 Credits /B.Sc. Microbiology Semester 5
  • MIC384/ Medical Bacteriology Lab / 2 Credits / B.Sc. Microbiology Semester 5
  • MIC510/ Parasitology and Mycology / 3 Credits / M.Sc. Microbiology Semester 3
  • MIC503/ Food Microbiology / 2 Credits /M.Sc. Microbiology Semester  3
  • MIC581/ Food Microbiology Lab / 2 Credits /M.Sc. Microbiology Semester  3
  • BIO201 / Human Physiology / 3 Credits / B.Sc. Biotechnology Semester 4
  • MIC111 / Parasitology / 3 Credits / B.Sc. Microbiolofgy Semester 6
  • BIO399 / Project / 7 Credits / B.Sc. Biotechnology Semester 6
Participation in Conferences and Workshops
i plant workshop,Amrita School of Biotechnology,Amritapuri,Kollam,Kerala. August 2014
Workshop on Introduction to research methodology-conducted by IIT Bombay -Amrita School of Engineering,Amritapuri,Kerala June 2012
Workshop on Basic Concepts in Modern Biology ,Amrita School of Biotechnology,Amritapuri,Kerala December 2006
Training workshop on AIDS,Kasturba Medical College,Manipal,Manipal University,Karnataka December 1998
XXII National congress of Indian association of Medical Microbiologists.Kasturba Medical College,Manipal,Manipal University,Karnataka. November 1998
Workshop on Rapid diagnostic techniques in Clinical microbiology with special emphasis to HIV and Tuberculosis,Kasturba Medical College,Manipal,Manipal University,Karnataka. November 1998
Awards and Recognitions

1. Essential oils modulate antibiotic mediated persister cell formation of P. aeruginosa. ‘International Webinar on Phytochemistry 2020’ organized by Kerala Academy of Sciences-Best paper presentation award
2. Modulation of Quorum Sensing and biofilm formation by furfural derivatives- International Conference on “Emerging Strategies in Antimicrobial Agents and Bio-Innovations” organized by RK University, Rajkot, Gujarat (India) in association with Microbiologist Society, India, and GSBTM.(2020-18th-20th Dec)-Best presentation award
3. Modulation of quorum sensing and biofilm formation by butyl Isothiocanate. Symbiot’21.National Biotechnology Symposium 16th October 2021 , MIT, Manipal-Best Paper presentation award.
4. Modulation of microbial virulence by activated furan compounds. 34th Kerala Sceince congress 2022, 10-12 February 2022. Best Poster presentation award.

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