Publication

Abstract : Quality of a product is very important, especially in the Pharmaceutical industry. To establish quality, every product requires certain analytical standards or parameters. These are more essential and mandatory, particularly in case of drugs and formulations. Present work is a comparative study on Yashada pushpa and Yashada bhasma with different analytical parameters. For preparing Yashada pushpa, Yashada was purified in general and specific purification methods. Then intense heat was given to the purified Yashada in a musha. Yashada bhasma taken for the study was procured from a GMP certified pharmacy. Both the samples were tested with modern and Ayurvedic parameters to know the physical and chemical characteristics of the products. Organoleptic characters gave an idea about the physical properties of the samples. The pH values showed that both the products were basic in nature. Loss on drying values or the moisture contents of both the samples were less. Ash values of the products showed that the organic matter present in both the samples was less. The XRD identified both the products as Zinc oxide. The Atomic absorption spectroscopy showed the presence of Zinc as major portion along with the other elements like Fe, Pb, Cu, Sn, Mg, Mn in the final product in both the samples. Scanning electron microscopy revealed that Pushpa had crystalline and polyhedral particles in it and bhasma had amorphous structure. Also Yashada bhasma had comparatively smaller particle size than Yashada pushpa. So Yashada bhasma may be better than pushpa in internal administration. Since the pharmaceutical processing of pushpa is comparatively easier and less time consuming than bhasma, Yashada pushpa can be used instead of bhasma where ever ZnO is used as external medicine.