Publication Type : Conference Paper
Publisher : 2017 International Conference on Technological Advancements in Power and Energy (TAP Energy)
Source : International Conference on Technological Advancements in Power and Energy (TAP Energy), IEEE, Kollam, India (2017)
Url : https://ieeexplore.ieee.org/abstract/document/8397256
Campus : Amritapuri
School : School of Arts and Sciences
Center : Computational Chemistry, Research & Projects
Department : Chemistry
Verified : Yes
Year : 2017
Abstract : Fabrication of the PVC membrane sensor incorporating clopidogrel-tetraido mercurate as an electro active material for the determination of clopidogrel bisulphate is demonstrated. Sensor matrix having a composition of PVC 32%, ion association 2.5% and Di-n-butyl phthalate 56.5 % showed best nernstian behavior in the concentration range 1×10 -2 -1×10 -7 M with a lower detection limit of 2.9 × 10 -8 M. Working pH range and response time was found to be 1.8-4.0 and 5s respectively. The sensor was fruitfully utilized for the quantification of clopidogrel from Clopilet tablets. Comparative studies on the various parameters that depend on the performance characteristics of the present sensor with that of the literature reports were also included.
Cite this Research Publication : Dr. Beena S., A Santhy, R Vidya, P Uma Sankar, and Rejithamol, R., “Clopidogrel-tetralodo mercurate ion association immobilized PVC membrane sensor for the determination of clopidogrel in pharmaceutical formulations”, in 2017 International Conference on Technological Advancements in Power and Energy (TAP Energy), Kollam, India, 2017.