Publication Type : Journal Article
Publisher : Wiley
Source : Early Intervention in Psychiatry
Url : https://doi.org/10.1111/eip.12117
Keywords : drug naïve; metabolic syndrome; schizophrenia
Campus : Faridabad
School : School of Medicine
Department : Psychiatry
Year : 2014
Abstract : AimThis study aimed to assess the prevalence of metabolic syndrome (MS) and subthreshold MS in antipsychotic naïve patients with schizophrenia by pooling the data from three different centres in India.MethodsOne hundred thirty‐seven antipsychotic naïve patients with schizophrenia were evaluated for MS using common criteria for clinical diagnosis.ResultsTwenty‐six patients (19%) met consensus criteria. Additionally, 56 patients (40.9%) fulfilled one criterion and 32 patients (23.3%) fulfilled two criteria of MS out of five criteria.ConclusionOne‐fifth of antipsychotic naïve patients with schizophrenia had MS and another two‐third had at least one metabolic abnormality. Awareness of such a high risk is vitally important for rational selection of antipsychotic medications as well as effective implementation of preventive measures.
Cite this Research Publication : Sandeep Grover, Naresh Nebhinani, Ramachandran Padmavati, Rakesh K Chadda, Srinivasan Tirupati, Abhishek Pallava, Metabolic syndrome in antipsychotic naïve patients with schizophrenia: pooled analysis of data from three