Publication

Abstract : pObjective: Arthritis have emerged to be a very common disorder affecting statistically one third of the population. The present study aims to investigate the effectiveness of Balapunarnavadi choornam, a polyherbal formulation in treating the disorder arthritis. The formulation is typically used in the treatment of anorexia and for improving digestion. Methodology: The anti-arthritic activity was investigated in-vitro by protein denaturation method. The aqueous extract of the choornam at different concentration was incubated with bovine serum albumin for complete denaturation and the result was assessed spectrophotometrically at 660nm against the standard diclofenac sodium. Result: The result revealed that the formulation possessed significant anti-arthritic activity and protein denaturation was inhibited by the extract at 200µg/ml - 1000µg/ml in comparison with diclofenac sodium, the standard drug used. Conclusion: The study concluded that the formulation is an effective inhibitor of protein denaturation and showed potent anti-arthritic activity. © 2017, Pharmainfo Publications. All rights reserved./p