Publication Type : Journal Article
Publisher : Journal of Cancer Research and Therapeutics
Source : Journal of Cancer Research and Therapeutics, Medknow Publications, Volume 13, Number 2, p.276-278 (2017)
Campus : Kochi
School : School of Pharmacy
Department : Pharmacognosy
Year : 2017
Abstract : Background: Curative intent treatments for malignancies using radiation therapy while achieving longer disease-free survivals, may also lead to solid second malignancies, a dreaded late complication. Both in-field as well as out-field second malignancies are encountered and lead to diagnostic dilemma, and delay in treatment. Materials and Methods: Details of a case of rare, in-field, radiation induced leiomyosarcoma, a rare soft tissue sarcoma, in a treated case of high risk carcinoma of prostate, who presented to our tertiary care centre was retrieved and analysed. Conclusion: Increasingly sophisticated radiotherapy techniques, while providing state of the art treatment options, does increase the potential risk of radiation-induced second-malignancies. Respecting integral-dose carries priority, until further studies elucidates mechanism of tumorigenesis. © 2017 Indian Journal of Ophthalmology | Published by Wolters Kluwer - Medknow.
Cite this Research Publication : C. G. Prameela and Ravind, R., “Leiomyosarcoma of scrotum: A rare in-field second malignancy in a previously irradiated carcinoma of prostate and review of literature”, Journal of Cancer Research and Therapeutics, vol. 13, pp. 276-278, 2017.