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Course Detail

Course Name Biophysics
Course Code 25PHY335
Program B. Sc. in Physics, Mathematics & Computer Science (with Minor in Artificial Intelligence and Data Science)
Semester Electives : Physics
Campus Mysuru

Syllabus

Unit I

Introduction: Laws of Physics and Chemistry, introduction to crystallography, Introduction to chromatography, electrophoresis Physico-Chemical Techniques to studyBiomolecules: hydration of macromolecules, diffusion of osmosis, sedimentation, ultracentrifuge, rotational dissuasion, light scattering, small angle X-ray scattering, Mass spectrometry.

Unit II

Spectroscopy: UV spectroscopy, circular dichroism, Fluorescence spectroscopy, IR, Raman and Electron spin spectroscopy, NMR spectroscopy.

Unit III

Molecular Modeling & Macromolecular Structure: building the structure of H2O2, , nucleic-acid structure, monomers, polymers, double helical structure of DNA, Polymorphism and nanostructure of DNA, structure of RNA, protein structure: amino acids, virus structure

Unit IV

Energy Pathways in Biology: free energy, couple reactions, group transfer potential, Pyridinenucleotides, photosynthesis, energy conversion pathways, membrane transport. Biomechanics: strained muscles, mechanical properties of muscles, cardiovascular-system.

 

Unit V

Neurobiophysics: nervous system, physics of membrane potentials, sensory mechanisms. Origin and evolution of life: prebiotic earth, theories of origin and evolution of life, laboratory experiments on formation of small molecules.

 

Objectives and Outcomes

OBJECTIVE: To enable students to study the selected biological phenomena using physical principles.

 

Course outcomes:

  1. Ability to explain the basics laws in physics and chemistry, various techniques to study biomolecules.
  2. Be able to apply various spectroscopic methods to study biomolecules.
  3. Ability to explain fundamentals of molecular modelling and macromolecular structure.
  4. Be able to apply the neuro science as application in biophysics.

 

CO – PO Mapping

  PO1 PO2 PO3 PO4 PO5 PO6 PO7 PO8 PO9 PO10 PSO1 PSO2 PSO3 PSO4
CO1 3 1 3 3 3 1 1       3 2 3  
CO2 3 1 3 3 3 1 1       3 2 3  
CO3 3 1 3 3 3 1 1       3 2 3  
CO4 3 1 3 3 3 1 1       3 2 3  

 

Text Books / References

Neurobiophysics: nervous system, physics of membrane potentials, sensory mechanisms. Origin and evolution of life: prebiotic earth, theories of origin and evolution of life, laboratory experiments on formation of small molecules.

 

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