Publication Type : Journal Article
Thematic Areas : Biotech
Publisher : Sensors and Actuators B: Chemical
Source : Sensors and Actuators B: Chemical, Volume 243, p.589 - 595 (2017)
Url : http://www.sciencedirect.com/science/article/pii/S0925400516319530
Keywords : Pseudoperoxidase activity
Campus : Amritapuri, Coimbatore
School : School of Biotechnology, School of Engineering
Center : Biosensor Research Lab, Biotechnology
Department : Sciences, biotechnology
Year : 2017
Abstract : Abstract A disposable non-enzymatic sensor for creatinine was developed by electrodepositing copper on screen printed carbon electrodes. The sensor was characterized using electrochemical and microscopic techniques. Electrochemical detection of creatinine was carried out in phosphate buffer solution of pH 7.4. The estimation was based on the formation of soluble copper-creatinine complex. The formation of copper-creatinine complex was established using the pseudoperoxidase activity of copper-creatinine complex. The sensor showed a detection limit of 0.0746 μM with a linear range of 6–378 μΜ. The sensor exhibited a stable response to creatinine and found to be free from interference from molecules like urea, glucose, ascorbic acid and dopamine. Real sample analysis was carried out with blood serum.
Cite this Research Publication : J. Raveendran, Resmi P. E., Dr. Ramachandran T., Dr. Bipin G. Nair, and Dr. Satheesh Babu T. G., “Fabrication of a disposable non-enzymatic electrochemical creatinine sensor”, Sensors and Actuators B: Chemical, vol. 243, pp. 589 - 595, 2017
