| Course Name | Organ Systems Physiology |
| Course Code | 24MM634 |
| Program | M. Tech. in Molecular Medicine(MLM) |
| Semester | 1 |
| Credits | 3 |
| Campus | Kochi |
This course builds on basic physiology and delves into individual organ systems and its cellular make up, their design, structure, and function. Each organ system will be discussed from a perspective of its function and how tissue and cellular hierarchies, in terms of their architecture and processes, contribute to organ system homeostasis. Current progress in terms of biomedical advancement in each organ system will also be explored.
Introduction, body water and distribution, regulation of water within extracellular, transcellular, and intracellular compartments, determination of compartmental fluid volumes, electrolyte distribution and their role in cell membrane potential
Blood the tissue and its components, serum, plasma, the coagulation process and dyscrasias, advancement in blood substitutes and their principle, and the lymphatic system
Cardiovascular system and the vascular tree, cardiac electrophysiology, arrythmias, pressure and volume changes in the ventricular chambers, cardiac cycle, valve kinetics, cardiac muscle physiology and calcium regulation, and cardiac biomedical technology
Pulmonary system, mechanics of ventilation, bronchial and alveolar cell functions geared to exchange gases, pulmonary function tests and assisted respiration technology
Hepatobiliary system, pancreas and the gut, hepatocyte architecture and function, blood-bile dynamics, pancreatic acini function, advancement in artificial liver and pancreas development, and gut physiology
Renal physiology, function of nephron, process of urine formation, pressures across the Bowmans membrane, and developments in body fluid dialysis
Nerve function, introductory neurophysiology, synapse physiology, neural circuits, signal processing in the special sense organs, cognition, and brain machine interface
Reproductive and endocrine system, hormonal axis, and regulation in various endocrine glands
Pre-requisites: Undergraduate level basic biology
Total number of classes: 45
Programme Outcomes (PO)(As given by NBA and ABET)
PO1: Bioscience Knowledge
PO2: Problem Analysis
PO3: Design/Development of Solutions
PO4: Conduct Investigations of complex problems
PO5: Modern tools usage
PO6: Bioscientist and Society
PO7: Environment and Sustainability
PO8: Ethics
PO9: Individual & Team work
PO10: Communication
PO11: Project management & Finance
PO12: Lifelong learning
| PO1 | PO2 | PO3 | PO4 | PO5 | PO6 | PO7 | PO8 | PO9 | PO10 | PO11 | PO12 | |
| CO1 | 3 | 1 | 1 | – | 1 | – | – | – | 3 | 2 | – | 1 |
| CO2 | 3 | 3 | 1 | – | 1 | – | – | – | 3 | 2 | – | 1 |
| CO3 | 3 | 3 | 3 | – | 1 | – | – | – | 3 | 2 | – | 1 |
| CO4 | 3 | 2 | 1 | – | 1 | – | – | – | 3 | 2 | – | 1 |
| CO5 | 2 | 1 | 3 | 2 | 1 | 3 | – | 2 | 3 | 2 | – | 1 |
Program Specific Outcomes. (PSO)
PSO 1 – Biochemical organization and cellular complexity in function
PSO 2 – Biomolecules in Medicine
PSO 3 – Molecular dysregulation in diseases
PSO 4 – Molecular technology in diagnosis and therapy
PSO 5 – Cell based approaches in diagnosis and therapy
PSO 6 – Microorganisms in Medicine
PSO 7 – Nanoscale entities and its significance in Medicine
PSO 8 – Tissue architecture engineering in Medicine
PSO 9 – Compounds as drugs and its efficacy
PSO 10 – Bioinformatics and biological data use
| PSO1 | PSO2 | PSO3 | PSO4 | PSO5 | PSO6 | PSO7 | PSO8 | PSO9 | PSO10 | |
| CO1 | 3 | 2 | – | – | – | – | – | – | – | – |
| CO2 | 3 | 3 | – | – | 2 | – | – | – | – | – |
| CO3 | 3 | 3 | 3 | 3 | 2 | – | – | – | – | – |
| CO4 | 3 | 2 | – | 2 | – | – | – | – | – | – |
| CO5 | 3 | 1 | 2 | 2 | 2 | – | 1 | 2 | – | – |
| Internal Assessment – 50% | ||
| Periodical 1 | Exam | 20% |
| Periodical 2 | Exam | 20% |
| Continuous Assessment | Assignment/Test/Quiz | 10% |
| 50% | ||
| End Semester Examination- 50% | ||
| Theory Exam | 50% | |
| 50% | ||
| Total | 100% |
John E. Hall, “Guyton and Hall Textbook of Medical Physiology”, 13e Elsevier, 2015
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