COURSE LEARNING OUTCOMES:
Upon successful completion of the course, the student shall be able to get,
KNOWLEDGE
K1 Discuss the principles of drug delivery carriers by controlling the composition/ processing conditions.
K2Describe the methods of preparation and evaluation of various drug carriers constructs like alginate beads, gelatin/albumin microspheres, liposomes, niosomes and spherules.
K3 Apply principles of pharmacokinetic data analysis of drugs administered by various routes.
K4 Plan the dissolution characteristics of dosage forms and protein binding affinity of drugs .
K5Prepare the clinical data collection manual.
K6Design of creams, shampoo and toothpaste by incorporation of herbal/synthetic constituents.
SKILL
S1 Optimize the drug delivery carriers by controlling the composition and processing conditions.
S2Develop various drug carrier constructs like alginate beads, gelatin/albumin microspheres, liposomes and niosomes, spherules.
S3 Determine the dissolution characteristics of marketed formulations
S4 Perform pharmacokinetic data analysis, permeability study, in vitro/ in silico techniques.
S5Design the formulation by Quality by Design (QBD) approach
S6Develop creams, shampoo, toothpaste, incorporation of herbal constituents.
ATTITUDE
A1Appreciate efforts taken meticulous attention to details. A2Embrace the quality control principles of product development. A3Cultivate the ability to think critically..
A4Foster group learning discussions.
A5 Participate effectively in team to achieve goals.
A6 Develop problem-solving ability.
PRACTICALS
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S.No.
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Experiments
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1.
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Effect of polymer concentration on formation of aspirin-loaded microspheres.
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2.
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Study the effect of polymer concentration in drug release of aspirin loaded microspheres.
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3.
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Effect of cholesterol concentration on formation of drug-loaded niosomes.
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4.
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Study the effect of cholesterol concentration on formation of niosomes/liposomes.
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5.
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Study the effect of cholesterol concentration on drug release of drug-loaded niosomes/liposomes.
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6.
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Stability studies of tablets.
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7.
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Comparison of dissolution of two marketed products/brands.
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8
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Protein binding studies of highly protein bound and poorly protein bound drugs.
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8.
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Analysis of pharmacokinetic data for one compartment model.
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9.
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Determination of PK parameters of drug from urinary elimination data.
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10
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Determination of steady state drug concentration after IV infusion.
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10.
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Determination of absorption rate constant by method of residuals.
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11.
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Perform in vitro permeability studies by open end tube.
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12
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Optimization of formulation by DOE.
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12.
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Apply QbD for the given drug product/process.
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13.
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ADME determination using Swiss-ADME software.
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14.
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Develop a clinical data collection manual.
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15.
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Preparation and evaluation of turmeric herbal cold cream/tomato extract vanishing cream.
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16.
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Preparation and evaluation of charcoal/fluoride gel tooth paste.
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17.
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Formulation and evaluation of polyherbal anti-aging face cream of rose and coriander extract.
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