Publication Type : Journal Article
Publisher : Springer
Source : Annals of hematology
Url : https://link.springer.com/article/10.1007/s00277-005-1044-2
Campus : Faridabad
School : School of Medicine
Year : 2005
Abstract : Hb S and Hb E are globally common hemoglobinopathies. However, Hb SE double heterozygous state is uncommon, with only 25 cases reported so far in literature. We present two more cases. One presented with gallstones, and the other was asymptomatic. This type of disorder was previously described as a relatively asymptomatic condition compared to HbSS. A review of the 25 reported cases in literature shows that 40.7% (11/27) of these cases are symptomatic. Gender, hematological parameters and levels of Hb S, E or F do not predict clinical severity.
Cite this Research Publication : Mishra, Pravas, H. P. Pati, Tathagat Chatterjee, Ashish Dixit, Dharma R. Choudhary, M. Upendra Srinivas, Manoranjan Mahapatra, and V. P. Choudhry. "Hb SE disease: a clinico-hematological profile." Annals of hematology 84 (2005): 667-670.