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Course Detail

Course Name Drug Delivery System
Course Code 24AIM441
Program B.Tech. Artificial Intelligence (AI) and Data Science (Medical Engineering)
Semester VII
Credits 3
Campus Coimbatore

Syllabus

Unit 1

Overview, dosage form-tablet, capsule, parenteral etc. classification of drug delivery system, chemically controlled system, diffusion-controlled system, controlled release mechanism-Membrane reservoir system, Matrix system, swelling controlled release system, biodegradable controlled release system.

Unit 2

Fundamental Aspects of Drug Delivery Introduction of pharmacokinetics and pharmacodynamics, diffusive transport, diffusion in heterogeneous system, passage of drug through membrane drug release kinetics from different biopolymer matrices

Unit 3

Pharmacokinetics Common routes of systemic drug administration, drug absorption, bio-availability, determinants of bio-availability disintegration, dissolution, drug distribution, drug elimination.

Unit 4

Matrix Based Drug Delivery System Delivery materials, polymer-based matrices; hydrogels- drug carriers, transdermal and trans-mucosal drug delivery system, measuring in vitro diffusions, measuring controlled release kinetics, drug targeting approaches, biocompatibility aspects of matrices Immunity and immunological preparations: immunity, types, immunological preparations; bacterial vaccines, vaccines containing living viruses, vaccines containing toxoids Fundamentals of vaccine delivery.

Course Objectives and Outcomes

Course Objectives:

  • To understand the basics about Drug Delivery system.
  • To understand the various ways of drug delivery
  • To know about pharmacokinetics and pharmacodynamics.
  • To understand the various aspects of Matrix based drug delivery system.

Course Outcomes:
After completing this course, students should be able to

  1. CO1: Understand the fundamental principles of drug delivery systems
  2. CO2: Classify different drug delivery systems
  3. CO3: Analyze the design and characteristics of membrane reservoir systems.
  4. CO4: Gain insights into the pharmacokinetics and pharmacodynamics of drug delivery

CPO-PO mapping

PO/P

SO

 PO 1 PO2 PO3 PO4 PO5 PO 6 PO7 PO8 PO 9 PO 10 PO 11 PO 12 PSO 1 PSO2 PSO3
CO
CO1 – – 1 1 – – – – 2 2 – 2 3 1 2
CO2 – – – 1 – – – – 2 2 – 2 3 1 2
CO3 – 2 – 1 – – – – 2 2 – 2 3 1 2
CO4 – – – 1 – – – – 2 2 – 2 3 1 2

Textbooks / References

  1. Drug Delivery: Fundamentals and Applications, Second Edition. (2016). United States: CRC Press.
  2. Drug Delivery: Principles and Applications. (2016). Germany: Wiley.
  3. Shargel, L., Yu, A. B. (2016). Applied Biopharmaceutics & Pharmacokinetics, Seventh Edition. Singapore: McGraw-Hill Education.
  4. Basic Pharmacokinetics and Pharmacodynamics: An Integrated Textbook and Computer Simulations. (2016). United Kingdom: Wiley

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