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Natural Products and Lead Discovery

About

The rapid advancements in modern biology have underscored the immense biotechnical potential of natural products. Plants, often regarded as genetically controlled natural chemical factories, have served as sources of valuable products for centuries. Despite the advent of modern techniques such as molecular modeling, combinatorial chemistry, and synthetic methods, natural products—particularly medicinal plants—continue to be a crucial source of new drugs or drug leads. The success of discovering naturally occurring therapeutic agents hinges on bioassay-guided fractionation and purification processes. To address the resource demands of an ever-growing population, it is imperative to revitalize the exploration of natural products to expand our resource base.

People

Dr. Chinchu Bose

Principal Investigators

Ms. Amabale Maniyanga

Research Scholars

Collaborations

  1. Prof.  Sanjit Dey, Head,  Department of Physiology, UCSTA, University of Calcutta,  Kolkata , for radiation protection
  2. Dr. J. Dinakara Adiga, Director, ICAR-Directorate of Cashew Research, Post Darbe, Puttur, D.K., Karnataka, India.
  3. Dr. Sushen Pradhan, Research Associate, Sikkim State Council of Science and Technology, Department of Science and Technology. Sikkim.India.
  4. Mr. Kashif Shariff, CEO and Director Mercuri Biotechnologies Bengaluru, Karnataka, India.
  5. Dr. Sreejit. C.M. Controller of Examinations, Mahatma Gandhi University, Kottayam Professor, Research Department of Botany, S.N.M. College,Maliankara, Kerala Ernakulam Dist, Kerala, India.
  6. Dr. M.G. Sanilkumar, Assistant Professor and Head of the Department, Research Department of Botany, S.N.M. College, Maliankara, Kerala Ernakulam Dist, Kerala, India

Projects

Biomimetic Elephant Deterrent System: Mitigating Human-Elephant Conflict in an Ecofriendly Manner

The studyaims to develop and evaluate a novel, deterrence system to minimize human-elephant conflict in India. This system will leverage the power of natural deterrents delivered in a specific sequence to effectively deter elephants without causing harm.

Therapeutic Potential of Desmodium Gangeticum Against Cardiac Hypertrophy

The objective of the study includes extraction and characterization of bioactive phytochemicals from Desmodiumgangeticum roots and evaluating its anti hypertrophic potential of the roots.

Screening of Phytochemicals for Antifungal Activity Against Soft Rot Disease Caused by Fusarium Oxysporum

Thestudy aims to evaluate the antifungal activity of phytochemicals against F.oxysporum which is the major cause for soft rot disease in ginger (Zingiber officinale.). India is the largest producer and exporter of ginger; it accounts for more than 70% of world’s production.

Herbal Thirst Buster Practice in Kerala: A Scientific Analysis

Kerala is renowned for its diverse range of herbal decoctions, prominently featuring ‘Dahashamani,’ a traditional infusion ubiquitous in local kitchens. The study explores the synbiotic relationship between traditionally used as Dahashamani and their health benefits with a special focus on gut microbiota

Contact us

Natural Products and Lead Discovery

Amrita Vishwa Vidyapeetham,
School of Biotechnology,
Amritapuri

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