Publication Type : Journal Article
Publisher : Tropical Doctor
Source : Tropical Doctor, 2017 Apr;47(2):136-141. doi: 10.1177/0049475517691878. Epub 2017 Feb 6.
Url : https://pubmed.ncbi.nlm.nih.gov/28166687/
Keywords : Dengue; hepatitis; mortality in dengue; severe dengue; thrombocytopenia; transaminase levels.
Campus : Kochi
School : School of Medicine
Department : General Medicine
Year : 2017
Abstract : Dengue fever is of great concern to public health in India as it contributes significantly to the burden of healthcare. The aim of our study was to measure mortality in dengue and its association with hepatitis and thrombocytopenia. Our study was performed in a tertiary care setting in the state of Kerala in southern India. Adult patients admitted in the year 2013 were included. Among 1308 confirmed dengue patients, the mortality rate was 1.76%. Hepatitis and thrombocytopenia were present in over 80% of all patients, but severe hepatitis was seen in 11.4% and severe thrombocytopenia in 9.3%. These were markers of fatal outcome. Other factors significantly associated with mortality were age >60 years, male sex, diabetes and the presence of any co-morbidity.
Cite this Research Publication : Smitha Krishnamoorthy, Arun N Bhatt, Celine Thalappillil Mathew, Abraham M Ittyachen, "Hepatitis and thrombocytopenia: markers of dengue mortality", Tropical Doctor, 2017 Apr;47(2):136-141. doi: 10.1177/0049475517691878. Epub 2017 Feb 6.