This symposium will present the current evidence from neuroscience, cognitive psychology, and social sciences to help understand how a healthy prefrontal system enables individuals to readjust behaviors, reappraise emotional reactivity and rethink social connections to achieve our goals and produce favorable results that benefit others as well as the future-self. Participants will discover that while the brain’s CEO is responsible for impulse control, sustained focus, long-term planning, gratification postponement, and emotional regulation, it does not arrive on the scene as a highly skilled and ready-to go entity; rather, it requires training, coaching, and guidance to master self-management skills. Lastly, every individual (student, faculty, or leader) needs strong Executive Function to activate motivation, predict performance challenges, and handle setbacks to reach their highest potential using ideas and strategies discovered by the progress neuroscience has made in the last 30 years.