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Publication Type : Journal Article
Source : J OrthopTraumatol. 2018 Jul 18;19(1):5
Url : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123315/
Campus : Faridabad
Year : 2018
Abstract : Background Proprioception is a specialized sensory modality encompassing the movement of the joint and its position in space. Reconstruction of the anterior cruciate ligament (ACL) does not always yield expected outcome, suggesting that successful reconstruction depends on not only the ultimate strength of the graft but also recovery of proprioception. Treatment delay is a significant concern in developing countries, e.g., in Asia. Thus, presence of mechanoreceptors is one of the factors having paramount importance for successful outcome. We conducted this study to identify mechanoreceptors via immunohistochemical staining and correlate their presence with duration of injury. Materials and methods A total of 38 injured native ACL stumps were harvested from patients undergoing ACL reconstruction and stained with neurofilament protein stain to detect functional mechanoreceptors. Results Of the specimens, 44.7% stained positive for monoclonal antibody. No association was found between duration of injury and presence of mechanoreceptors (p = 0.897). No correlation was seen between age and side. Conclusions No correlation was found between duration of injury and presence of viable mechanoreceptors, hence it is beneficial to preserve the native ACL stump irrespective of the time interval between injury and surgery.
Cite this Research Publication : Nayak M, Nag HL, Gaba S, Nag TC, Sharma S. Quantitative comparison of mechanoreceptors in the tibial remnants of the ruptured human anterior cruciate ligament with duration of injury and its significance: An Immunohistochemistry based observational study. J OrthopTraumatol. 2018 Jul 18;19(1):5. doi: 10.1186/s10195-018-0498-7.