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Impact of width and spacing of interdigitated electrode on impedance-based living cell monitoring studied by computer simulation

Publication Type : Conference Proceedings, Journal Article

Publisher : IOP Science

Source : Japanese Journal of Applied Physics, Volume 59, Number SD

Url : https://iopscience.iop.org/article/10.7567/1347-4065/ab4eb0

Campus : Bengaluru

School : School of Engineering

Department : Electronics and Communication

Year : 2019

Abstract : The 3D computer simulation based on the finite element method was performed to obtain the impedance in the presence/absence of adherent living cells. The sensitivity of the inter-digitated electrode was investigated by varying the width (W) and spacing (S) for different number of electrode fingers N. It was found that the peak sensitivity corresponding to W/S < 1 and W/S > 1 exhibited higher sensitivity than W/S = 1. However, the sensitivity was relatively large when W/S < 1. Furthermore, the slope of the peak sensitivity curve decreased with the increase in N, emphasizing the fact that it has greater impact on sensitivity than W/S. It is important to note that the peak sensitivity due to smaller electrode width results in higher sensitivity. Hence, the experimentalists are recommended to choose the smaller electrode geometry with smaller electrode width in order to realize better sensitivity in the presence of adherent cell.

Cite this Research Publication : Pooja Kenchetty, Taiki Miura, Shigeyasu Uno, "Impact of width and spacing of interdigitated electrode on impedance-based living cell monitoring studied by computer simulation", 2020 Japanese Journal of Applied Physics, 59, SDDE02

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