Publication

Abstract : Summary Nanobioconjugates are hybrid components that deal with the intellectual properties of nanomaterials and biomolecules. However, these interesting properties strongly depend on the surface chemistry of nanoparticles, which changes the physical dimensions of the particulate in the biological system. Such changes have emerged as researchers explore nanobioconjugates for their potential applications in biology and medicine. In particular, noble metal nanoparticles, quantum dots, silica nanoparticles, metal oxides, and carbon nanomaterials are gaining much interest owing to their unique properties, which lead to undergoing conjugation with biomolecules like enzymes, proteins, antibodies, and genetic materials to develop the nano–bio interface. Such hybrid interfaces of nanomaterials with biomolecules are either by physical adsorption or by covalent linkage toward tunable biological functions, which are used for biosensing, biochips, bioimaging, and biomedical applications. This chapter mainly covers the methods developed for the fabrication of nanobioconjugated systems and the unique studies on bioelectrochemical applications.