‘Pharmaceutical Organic Chemistry II – Practical’ is a course offered in the third semester of B. Pharm program at School of Pharmacy, Health Sciences campus, Amrita Vishwa Vidyapeetham.

Course Duration: 4 Hours/Week

1. Determination of radiation constant of brass, iron, unpainted and painted glass.
2. Steam distillation – To calculate the efficiency of steam distillation.
3. To determine the overall heat transfer coefficient by heat exchanger.
4. Construction of drying curves (for calcium carbonate and starch).
5. Determination of moisture content and loss on drying.
6. Determination of humidity of air – i) From wet and dry bulb temperatures –use of Dew point method.
7. Description of Construction working and application of Pharmaceutical Machinery such as rotary tablet machine, fluidized bed coater, fluid energy mill, de humidifier.
8. Size analysis by sieving – To evaluate size distribution of tablet granulations – Construction of vari- ous size frequency curves including arithmetic and logarithmic probability plots.
9. Size reduction: To verify the laws of size reduction using ball mill and determining Kicks, Ritting- er’s, Bond’s coefficients, power requirement and critical speed of Ball Mill.
10. Demonstration of colloid mill, planetary mixer, fluidized bed dryer, freeze dryer and such other major equipment.
11. Factors affecting Rate of Filtration and Evaporation (Surface area, Concentration and Thickness/ viscosity
12. To study the effect of time on the Rate of Crystallization.
13. To calculate the uniformity Index for given sample by using Double Cone Blender.