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Publication Type : Journal Article
Publisher : International Journal of Pharmaceutical and Clinical Research
Source : International Journal of Pharmaceutical and Clinical Research , vol. 9, no. 1, pp. 96-99, 2017
Url : http://impactfactor.org/PDF/IJPCR/9/IJPCR,Vol9,Issue1,Article18.pdf
Campus : Kochi
School : School of Pharmacy
Department : Pharmacy Practice
Verified : Yes
Year : 2017
Abstract : The well-established indications for anticoagulant therapy include atrial fibrillation, venous thromboembolism (VTE) and mechanical heart valves. Vitamin K antagonists are the most common anticoagulants used in the outpatient setting. Two new classes of anticoagulants (direct thrombin and factor Xa inhibitors) have shown promise as alternatives to the vitamin K antagonists. Specifically, dabigatran, rivaroxaban and apixaban have been studied in comparison to warfarin for their use in preventing systemic stroke/embolism in patients with atrial fibrillation and for managing the recurrence of VTE. This article will review the literature on the efficacy of these agents, as well as the benefits and disadvantages of their use.
Cite this Research Publication : R. Krishna, Kumar, B. Santhosh, Krishnan, S., Anila K. N., and Lakshmi R., “A Review of Novel Anticoagulants”, International Journal of Pharmaceutical and Clinical Research , vol. 9, no. 1, pp. 96-99, 2017