Publisher : International Journal of Pharmacy and Pharmaceutical Sciences
Campus : Kochi
School : School of Pharmacy
Department : Pharmacy Practice
Verified : Yes
Year : 2017
Abstract : Takayasu’s arteritis (TA) is a rare large-vessel vasculitis that affects large arteries, mainly the aorta and its branches. It is also called a pulselessdisease because of diminished or absent pulses in the upper extremities of the patient. The coronary, pulmonary and renal arteries are also affectedin the progression of the disease. The prevalence of the disease is more in Asian countries and it has unknown etiopathogenesis. Here we discuss acase of TA in a 15 y old girl who was admitted with moderate LV dysfunction. The diagnosis was carried out from the results of CT aortogram whichshowed stenosis of right common carotid, left subclavian, left vertebral artery, right renal artery and lower lobe pulmonary arteries and otherclinical examinations. Treatment was initiated with methylprednisolone and cyclophosphamide along with symptomatic treatment. But the diseaseprogressed with the development of complications like peripheral leg ulcers. The patient was initiated palliative care in view of altered sensoriumand severe LV dysfunction, but the patient succumbed to a sudden cardiac arrest. Early identification and initiation of aggressive treatment can helpin symptom-free survival.