Publications

Abstract : Modeling and simulation techniques have been used extensively to study the complexities of brain circuits. Simulations of bio-realistic networks consisting of large number of neurons require massive computational power when they are designed to provide real-time responses in millisecond scale. A network model of cerebellar granular layer was developed and simulated here on Graphic Processing Units (GPU) which delivered a high compute capacity at low cost. We used a mathematical model namely, Adaptive Exponential leaky integrate-and-fire (AdEx) equations to model the different types of neurons in the cerebellum. The hypothesis relating spatiotemporal information processing in the input layer of the cerebellum and its relations to sparse activation of cell clusters was evaluated. The main goal of this paper was to understand the computational efficiency and scalability issues while implementing a large-scale microcircuit consisting of millions of neurons and synapses. The results suggest efficient scale-up based on pleasantly parallel modes of operations allows simulations of large-scale spiking network models for cerebellum-like network circuits.