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Development of activated carbon-ceria nanocomposite materials for prostate cancer therapy

Publication Type : Journal Article

Thematic Areas : Nanosciences and Molecular Medicine

Publisher : Advanced Science, Engineering and Medicine

Source : Advanced Science, Engineering and Medicine (2013)

Campus : Kochi

School : Center for Nanosciences

Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences

Department : Nanosciences

Verified : Yes

Year : 2013

Abstract : Using electrophoretic co-deposition (EPD), nanocomposite of ball-milled activated carbon and cerium (IV) oxide (CeO2) (or) ceria was prepared as a thin film. Nanocomposite preparation was done and deposited on aluminium foil. Phase analyses were carried out using X-ray diffraction analysis (XRD) showing the uniform compositional profile of the composite. The elemental analysis of ceria, oxygen and carbon was carried out using X-ray photoelectron spectroscopy (XPS). Detailed scanning electron microscopy analysis showed that ball-milled activated carbon, ceria and carbon-ceria composite were formed on the nanoscale and uniformly distributed. The toxicity of activated carbon ceria nanocomposite towards the prostate cancer cell line was evaluated and found to be toxic towards prostate cancer cell lines (PC-3) as analyzed by MTT assay.

Cite this Research Publication : , K.V., S., G., R., Shantikumar V Nair, K.R.V, S., and V.-K., L., “Development of activated carbon-ceria nanocomposite materials for prostate cancer therapy”, Advanced Science, Engineering and Medicine, 2013.

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