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A new synthetic approach to 7-hydroxynitidine

Publication Type : Journal Article

Publisher : Tetrahedron Letters

Source : Tetrahedron Letters, Volume 49, Number 36, p.5262 - 5264 (2008)

Url : http://www.sciencedirect.com/science/article/pii/S0040403908012306

Keywords : Radical cyclization

Campus : Coimbatore

School : School of Engineering

Department : Sciences

Year : 2008

Abstract : pBenzo[c]phenanthridine alkaloid, 7-hydroxynitidine, was synthesized from readily available 2-benzyloxy-6-bromo-3,4-dimethoxybenzaldehyde 5 and napthylamine 6 using reductive amination followed by radical cyclization in eight steps. This method is highly efficient and better way to synthesize fully aromatized benzo[c]phenanthridine compounds./p

Cite this Research Publication : Dr. Prasanna Ramani and Fontana, G., “A new synthetic approach to 7-hydroxynitidine”, Tetrahedron Letters, vol. 49, pp. 5262 - 5264, 2008.

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