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Dr. S. Sathianarayanan

Asst. Professor

Dr.  S. Sathianarayanan currently serves as Assistant Professor at the Department of Pharmaceutical Chemistry & Analysis, School of Pharmacy, Health Science Campus, Kochi.

Qualification: M. Pharm., Ph.D
sathyanarayanans@aims.amrita.edu
Research Interest: Phytochemical & Pharmacological Investigation of Herbs

Bio

Dr. Sathianarayanan joined as lecturer in the Department of Pharmaceutical Chemistry at Amrita in February 2007. He completed his B. Pharm. and M. Pharm. from Dr. M G R Medical University, Chennai. He received his Ph. D. in Pharmacy from Karpagam University, Coimbatore.

Dr. Sathianarayanan’s interests broadly include Semi-synthetic, Synthetic and Phytochemical Analysis. He has a strong academic background and extensive research experience with specialization in isolation and characterization of biologically active compounds. He has knowledge in docking studies, experimental pharmacology and handling of animals like rat, mice and rabbit to screen various pharmacological action.

Currently, he is involved in the Study of Isolation and Characterization of Bioactive Compounds from Herbs and Marine Organisms and Derivatization of Phytoconstituents, including the design, synthesis and development of bioactive heterocyclic compounds for the treatment of infectious diseases, cancer and immune related disorders. It is hoped that this novel approach will help a newer drug development with safety and efficacy.

He received a major funded project from Ministry of Earth Sciences of Rs 75.60 lakhs for the study titled High Through Put Screening of Biological Activity of Extracts from Deep Sea Marine Organisms. The Kerala State Council For Science, Technology and Environment has also funded for the Study – Synthesis of some Novel Scaffold for Anti-Prostate Cancer.

A text book titled Pharmaceutical Analytical Chemistry authored by Dr. Sathianarayanan was published by Birla Publications Pvt. Ltd, New Delhi. The book mainly focuses on the needs of undergraduate and postgraduate pharmacy students. It explains the science and application of modern and traditional techniques for the analysis of pharmaceutical products.

In his capacity as guide, he is mentoring B. Pharm. and M. Pharm. Thesis Projects some of which include:

  1. Phytochemical investigation and various pharmacological evaluation of Andrographis paniculata and Swertia chirayita.
  2. Phytochemical investigation and pharmacological screening of Ventilago madraspatana as an immunomodulator.
  3. Insilico design and synthesis of some novel Isatin and Quinazoline derivatives against mammary carcinoma.
  4. Design, synthesis and biological evaluation of anti-prostate cancer agents.
  5. Phytochemical and pharmacological screening of Wrightia tinctoria.
  6. Anthelmintic, antioxidant and immunomodulatory activity of methanolic extracts of Wrightia tinctoria leaves.
  7. Phytochemical screening and anticancer activity of Indigofera tinctoria.
  8. Synthesis, anticancer activity and QSAR analysis of substituted derivatives containing Indole moiety.
  9. In-vitro cytotoxic and antimicrobial activity of microwave assisted synthesized Isatin derivative.
  10. Insilico design and molecular docking studies of PDE-4 inhibitors for the treatment of psoriasis using some new Andrographolide, Isatin and Emodin derivatives.
  11. Priliminary phytochemical investigation and invitro anti-inflammatory activity of Sargassum wightii (Greville).
  12. Insilico design and synthesis of novel anti-inflammatory agents.
  13. Anti oxidant and cytotoxic activity of deep sea marine organism Hetractic magnifica.
Publications

Journal Article

Anticancer activity of chloroform extract of Helisteres isora

Authors : Dr. S. Sathianarayanan, Vargheese, E., Gopal, R. Vijaya, Nair, A., Chittethu, A. B

Publisher : IJPT

Preliminary Phytochemical Screening and cytotoxic activity of Ethenolic Extract of Ventilago Madraspatana

Authors : Dr. S. Sathianarayanan, Chittethu, A. B., .Sathianarayanan, S., Nair, A., Varghese, E., and Gopal, R. Vijaya

Publisher : Int. J. Pharmacol. Bio.Sci.

Pharmacoeconomics:Need for Introduction in Indian Healthcare

Authors : Dr. S. Sathianarayanan, K.Shankar, B., Abraham, S., George, R. Mary, and Jose, A

Publisher : Indian Journal of Hospital Pharmacy

Evaluation of Protective Effect of Luffa acutangula Extract against Bilateral Carotid artery occlusion (BCAO) induced strock in rats

Authors : Dr. S. Sathianarayanan, Jose, A., Rajasekharan, A., George, R. Mary, and Chittethu, A. B

Publisher : Indian Journal of Pharmaceutical Science and Research,

In-silico docking studies of coumarin derivatives as capsase * and PDE4 Antagonist.

Authors : Dr. S. Sathianarayanan, Prasad, N., Josna, K. Joy, S, S. Nair, Ashokan, A. Asha

Publisher : Research Journal of Pharmacy and Technology

A Computational approach for identification of Phytochemicals for targeting and optimizing the inhibitors of Heat shock proteins

Authors : Saranya T. S., Dr. S. Sathianarayanan, Revathy S Kumar, V, S., Menon, S. V., Mohan, S., Asha Asokan Manakadan, and Suja, S

Publisher : Research Journal of Pharmacy and Technology.

Immunomodulatory Activity of ethanolic extract of Wrightia tinctoria Leaves

Authors : Dr. S. Sathianarayanan, Rajasekharan, A

Publisher : International Journal of Pharmacy and Pharmaceutical Sciences.

Immunomodulatory Activity of methanolic extract of Wrightia tinctoria Leaves

Authors : Dr. S. Sathianarayanan, Jose, A

Publisher : International Journal of Advanced Pharmacology and Toxicology

Diuretic activity of aqueous and alcoholic extracts of Wrightia tinctoria

Authors : Dr. S. Sathianarayanan, Jose, A., ,, George, R. Mary, P, A., Chittethu

Publisher : International Journal of Phytopharmacology

Phytochemical Screening and Antimicrobial investigation of Typha angustifolia linn.

Authors : Dr. S. Sathianarayanan, Varghese, A., Gavani, U., Abraham, S., and Parambi, D. Grace Thom

Publisher : International Journal of Chemical Science

Aticancer activity of chloroform extract of Helicteres ISORA

Authors : Dr. S. Sathianarayanan, E. Varghese, Gopal, R. V., Nair, A., Chittethu, A. B., and Anson, T. A.

Publisher : International Journal of Pharmacy and Technology

Quality Pharmaceutical Education in India-Need of the Hour

Authors : Dr. S. Sathianarayanan, Abraham, S

Publisher : The Indian Journal of Technical Education

Prophylaxis in migraine management

Authors : Dr. Aneesh T. P., Dr. S. Sathianarayanan, S. M Sekhar, JinyVarghese, K., Vasudevan, D., and Revikumar, K

Publisher : Journal of Young Pharmacists

Preliminary phytochemical screening and study of antiviral activity and cytotoxicity of Wrightia tinctoria.

Authors : Dr. S. Sathianarayanan, Selvam, P., Jose, A., George, R. Mary, and .G.Ravikumar, K

Publisher : International Journal of Chemical Science

A Modern Tool For Pharmacology.

Authors : Dr. S. Sathianarayanan, Baby, J. C. T

Publisher : The Internet Journal of Medical Simulation

Holistic way to green life

Authors : Dr. S. Sathianarayanan, N.Fasmi

Publisher : The Internet Journal of Alternative Medicine

Effect of Ampicillin Soduium on Immune Response.

Authors : Dr. S. Sathianarayanan, Abraham, S

Publisher : Journal of Pharmacy Research

Diuretic activity of aqueous and alcoholic extracts of Justicia tranqurbariensis

Authors : Dr. S. Sathianarayanan, Jose, A., Abraham, S., and Thomas, D. Grace

Publisher : International Journal of Advanced Pharmacology and Biological Sciences

Antimicrobial activity of various extracts of Justicia tranqurbariensis

Authors : Dr. S. Sathianarayanan, Saravanakumar, A., Baby, L. Trisa, and Abraham, S.

Publisher : International Journal of Advanced Pharmacology and Toxicology

Absorption and Metabolism Of Xenobiotics: An Overview

Authors : Dr. S. Sathianarayanan, Abraham, S., and Varghese, A

Publisher : The Internet Journal of Nutrition and Wellness.

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